Search details
1.
Advancing Biological Understanding and Therapeutics Discovery with Small-Molecule Probes.
Cell
; 161(6): 1252-65, 2015 Jun 04.
Article
in English
| MEDLINE | ID: mdl-26046436
2.
The reversible inhibitor SR-4835 binds Cdk12/cyclin K in a noncanonical G-loop conformation.
J Biol Chem
; 300(1): 105501, 2024 Jan.
Article
in English
| MEDLINE | ID: mdl-38016516
3.
Sculpting a Uniquely Reactive Cysteine Residue for Site-Specific Antibody Conjugation.
Bioconjug Chem
; 33(6): 1192-1200, 2022 06 15.
Article
in English
| MEDLINE | ID: mdl-35584359
4.
Development of a putative Zn2+-chelating but highly selective MMP-13 inhibitor.
Bioorg Med Chem Lett
; 76: 129014, 2022 11 15.
Article
in English
| MEDLINE | ID: mdl-36202189
5.
An Engineered Arginine Residue of Unusual pH-Sensitive Reactivity Facilitates Site-Selective Antibody Conjugation.
Biochemistry
; 60(14): 1080-1087, 2021 04 13.
Article
in English
| MEDLINE | ID: mdl-33754696
6.
Development of matrix metalloproteinase-13 inhibitors - A structure-activity/structure-property relationship study.
Bioorg Med Chem
; 26(18): 4984-4995, 2018 10 01.
Article
in English
| MEDLINE | ID: mdl-30249495
7.
Identification of cysteine protease inhibitors as new drug leads against Naegleria fowleri.
Exp Parasitol
; 188: 36-41, 2018 May.
Article
in English
| MEDLINE | ID: mdl-29551628
8.
Chemically Programmed Bispecific Antibodies in Diabody Format.
J Biol Chem
; 291(37): 19661-73, 2016 09 09.
Article
in English
| MEDLINE | ID: mdl-27445334
9.
Stolonidiol: Synthesis, Target Identification, and Mechanism for Choline Acetyltransferase Activation.
J Am Chem Soc
; 139(16): 5865-5869, 2017 04 26.
Article
in English
| MEDLINE | ID: mdl-28414442
10.
Novel Pharmacological Probes Reveal ABHD5 as a Locus of Lipolysis Control in White and Brown Adipocytes.
J Pharmacol Exp Ther
; 363(3): 367-376, 2017 12.
Article
in English
| MEDLINE | ID: mdl-28928121
11.
Suppression of TH17 differentiation and autoimmunity by a synthetic ROR ligand.
Nature
; 472(7344): 491-4, 2011 Apr 28.
Article
in English
| MEDLINE | ID: mdl-21499262
12.
Human Serum Albumin Domain I Fusion Protein for Antibody Conjugation.
Bioconjug Chem
; 27(10): 2271-2275, 2016 10 19.
Article
in English
| MEDLINE | ID: mdl-27666414
13.
Assessment of reagents for selenocysteine conjugation and the stability of selenocysteine adducts.
Org Biomol Chem
; 14(22): 5141-7, 2016 Jun 14.
Article
in English
| MEDLINE | ID: mdl-27184239
14.
Antiproliferation activity of a small molecule repressor of liver receptor homolog 1.
Mol Pharmacol
; 87(2): 296-304, 2015 Feb.
Article
in English
| MEDLINE | ID: mdl-25473120
15.
Casein kinase 1δ-dependent Wee1 protein degradation.
J Biol Chem
; 289(27): 18893-903, 2014 Jul 04.
Article
in English
| MEDLINE | ID: mdl-24817118
16.
Site-Specific Dual Antibody Conjugation via Engineered Cysteine and Selenocysteine Residues.
Bioconjug Chem
; 26(11): 2243-8, 2015 Nov 18.
Article
in English
| MEDLINE | ID: mdl-26161903
17.
Expanding the binding envelope of CYP51 inhibitors targeting Trypanosoma cruzi with 4-aminopyridyl-based sulfonamide derivatives.
Chembiochem
; 15(8): 1111-20, 2014 May 26.
Article
in English
| MEDLINE | ID: mdl-24771705
18.
Enantio- and diastereoselective synthesis of N-acetyl dihydrotetrafibricin methyl ester.
J Am Chem Soc
; 135(14): 5340-3, 2013 Apr 10.
Article
in English
| MEDLINE | ID: mdl-23530855
19.
Enantioselective synthesis of (Z)- and (E)-2-methyl-1,5-anti-pentenediols via an allene hydroboration-double-allylboration reaction sequence.
J Am Chem Soc
; 135(25): 9512-7, 2013 Jun 26.
Article
in English
| MEDLINE | ID: mdl-23758559
20.
Crotylboron-based synthesis of the polypropionate units of chaxamycins A/D, salinisporamycin, and rifamycin S.
J Org Chem
; 78(1): 3-8, 2013 Jan 04.
Article
in English
| MEDLINE | ID: mdl-22703288