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1.

Microbiotas from Humans with Inflammatory Bowel Disease Alter the Balance of Gut Th17 and RORÎ³t⁺ Regulatory T Cells and Exacerbate Colitis in Mice.

Britton, Graham J; Contijoch, Eduardo J; Mogno, Ilaria; Vennaro, Olivia H; Llewellyn, Sean R; Ng, Ruby; Li, Zhihua; Mortha, Arthur; Merad, Miriam; Das, Anuk; Gevers, Dirk; McGovern, Dermot P B; Singh, Namita; Braun, Jonathan; Jacobs, Jonathan P; Clemente, Jose C; Grinspan, Ari; Sands, Bruce E; Colombel, Jean-Frederic; Dubinsky, Marla C; Faith, Jeremiah J.

Immunity ; 50(1): 212-224.e4, 2019 01 15.

Article in English | MEDLINE | ID: mdl-30650377

2.

Mirikizumab as Induction and Maintenance Therapy for Ulcerative Colitis.

D'Haens, Geert; Dubinsky, Marla; Kobayashi, Taku; Irving, Peter M; Howaldt, Stefanie; Pokrotnieks, Juris; Krueger, Kathryn; Laskowski, Janelle; Li, Xingyuan; Lissoos, Trevor; Milata, Joe; Morris, Nathan; Arora, Vipin; Milch, Catherine; Sandborn, William; Sands, Bruce E.

N Engl J Med ; 388(26): 2444-2455, 2023 Jun 29.

Article in English | MEDLINE | ID: mdl-37379135

3.

Subcutaneous Infliximab (CT-P13 SC) as Maintenance Therapy for Inflammatory Bowel Disease: Two Randomized Phase 3 Trials.

Hanauer, Stephen B; Sands, Bruce E; Schreiber, Stefan; Danese, Silvio; Klopocka, Maria; Kierkus, Jaroslaw; Kulynych, Roman; Gonciarz, Maciej; Soltysiak, Artur; Smolinski, Patryk; Sreckovic, Slobodan; Valuyskikh, Ekaterina; Lahat, Adi; Horynski, Marek; Gasbarrini, Antonio; Osipenko, Marina; Borzan, Vladimir; Kowalski, Maciej; Saenko, Daria; Sardinov, Ruslan; Lee, Sang Joon; Kim, Sunghyun; Bae, Yunju; Lee, Sunhee; Lee, Seulgi; Lee, Joon Ho; Yang, Siyoung; Lee, Jimin; Lee, Juhyun; Kim, Jong Min; Park, Gahee; Sandborn, William J; Colombel, Jean-Frederic.

Gastroenterology ; 2024 May 22.

Article in English | MEDLINE | ID: mdl-38788861

4.

Etrasimod as induction and maintenance therapy for ulcerative colitis (ELEVATE): two randomised, double-blind, placebo-controlled, phase 3 studies.

Sandborn, William J; Vermeire, Séverine; Peyrin-Biroulet, Laurent; Dubinsky, Marla C; Panes, Julian; Yarur, Andres; Ritter, Timothy; Baert, Filip; Schreiber, Stefan; Sloan, Sheldon; Cataldi, Fabio; Shan, Kevin; Rabbat, Christopher J; Chiorean, Michael; Wolf, Douglas C; Sands, Bruce E; D'Haens, Geert; Danese, Silvio; Goetsch, Martina; Feagan, Brian G.

Lancet ; 401(10383): 1159-1171, 2023 04 08.

Article in English | MEDLINE | ID: mdl-36871574

5.

Washout Periods in Inflammatory Bowel Disease Trials: A Systematic Literature Review and Proposed Solutions.

Wils, Pauline; Jairath, Vipul; Sands, Bruce E; Reinisch, Walter; Danese, Silvio; Peyrin-Biroulet, Laurent.

Clin Gastroenterol Hepatol ; 22(4): 896-898.e13, 2024 Apr.

Article in English | MEDLINE | ID: mdl-37743039

6.

Evolution of Symptoms After Ustekinumab Induction Therapy in Patients With Crohn's Disease.

Colombel, Jean-Frédéric; Sands, Bruce E; Gasink, Christopher; Yeager, Benjamin; Adedokun, Omoniyi J; Izanec, James; Ma, Tony; Gao, Long-Long; Lee, Scott D; Targan, Stephan R; Ghosh, Subrata; Hanauer, Stephen B; Sandborn, William J.

Clin Gastroenterol Hepatol ; 22(1): 144-153.e2, 2024 01.

Article in English | MEDLINE | ID: mdl-37391056

7.

Ozanimod in Patients With Moderate to Severe Ulcerative Colitis Naive to Advanced Therapies.

Sands, Bruce E; D'Haens, Geert; Panaccione, Remo; Regueiro, Miguel; Ghosh, Subrata; Hudesman, David; Ahmad, Harris A; Mehra, Dimpy; Wu, Hsiuanlin; Jain, Anjali; Petersen, AnnKatrin; Osterman, Mark T; Afzali, Anita; Danese, Silvio.

Clin Gastroenterol Hepatol ; 2024 May 07.

Article in English | MEDLINE | ID: mdl-38723981

8.

Guselkumab in Patients With Moderately to Severely Active Ulcerative Colitis: QUASAR Phase 2b Induction Study.

Peyrin-Biroulet, Laurent; Allegretti, Jessica R; Rubin, David T; Bressler, Brian; Germinaro, Matthew; Huang, Kuan-Hsiang Gary; Shipitofsky, Nicole; Zhang, Hongyan; Wilson, Rebbecca; Han, Chenglong; Feagan, Brian G; Sandborn, William J; Panés, Julian; Hisamatsu, Tadakazu; Lichtenstein, Gary R; Sands, Bruce E; Dignass, Axel.

Gastroenterology ; 165(6): 1443-1457, 2023 Dec.

Article in English | MEDLINE | ID: mdl-37659673

9.

Anti-Integrin αvß6 Autoantibodies Are a Novel Biomarker That Antedate Ulcerative Colitis.

Livanos, Alexandra E; Dunn, Alexandra; Fischer, Jeremy; Ungaro, Ryan C; Turpin, Williams; Lee, Sun-Ho; Rui, Shumin; Del Valle, Diane Marie; Jougon, Julia J; Martinez-Delgado, Gustavo; Riddle, Mark S; Murray, Joseph A; Laird, Renee M; Torres, Joana; Agrawal, Manasi; Magee, Jared S; Dervieux, Thierry; Gnjatic, Sacha; Sheppard, Dean; Sands, Bruce E; Porter, Chad K; Croitoru, Kenneth; Petralia, Francesca; Colombel, Jean-Frederic; Mehandru, Saurabh.

Gastroenterology ; 164(4): 619-629, 2023 04.

Article in English | MEDLINE | ID: mdl-36634824

10.

Efficacy and Safety of Ustekinumab for Ulcerative Colitis Through 4 Years: Final Results of the UNIFI Long-Term Maintenance Study.

Afif, Waqqas; Arasaradnam, Ramesh P; Abreu, Maria T; Danese, Silvio; Sandborn, William J; Miao, Ye; Zhang, Hongyan; Panaccione, Remo; Hisamatsu, Tadakazu; Scherl, Ellen J; Leong, Rupert W; Rowbotham, David S; Peyrin-Biroulet, Laurent; Sands, Bruce E; Marano, Colleen.

Am J Gastroenterol ; 2024 Jan 26.

Article in English | MEDLINE | ID: mdl-38095692

11.

Baseline Clinical Factors Are Associated With Risk of Complications in Crohn's Disease: Appraisal of the American Gastroenterological Association Clinical Care Pathway.

Santiago, Priscila; Coelho-Prabhu, Nayantara; Lennon, Ryan; Rui, Shumin; Rajauria, Palak; Friton, Jessica; Raffals, Laura E; Deepali, Fnu; Daoud, Nader; Farraye, Francis A; Tuck, Jaclyn; Malik, Talha; Leleiko, Neal S; Shapiro, Jason; Shah, Samir A; Sands, Bruce E; Ungaro, Ryan C.

Am J Gastroenterol ; 119(1): 147-154, 2024 Jan 01.

Article in English | MEDLINE | ID: mdl-37713528

12.

Impact of Biologics and Small-Molecule Agents on Postoperative Complications in IBD: A Systematic Review.

Lee, Kate E; Sizemore, J Alexander; Kim, Grace; Shen, Bo; Sands, Bruce E.

Dis Colon Rectum ; 67(S1): S11-S25, 2024 Jun 01.

Article in English | MEDLINE | ID: mdl-38294838

13.

Biopsy and blood-based molecular biomarker of inflammation in IBD.

Argmann, Carmen; Hou, Ruixue; Ungaro, Ryan C; Irizar, Haritz; Al-Taie, Zainab; Huang, Ruiqi; Kosoy, Roman; Venkat, Swati; Song, Won-Min; Di'Narzo, Antonio F; Losic, Bojan; Hao, Ke; Peters, Lauren; Comella, Phillip H; Wei, Gabrielle; Atreja, Ashish; Mahajan, Milind; Iuga, Alina; Desai, Prerak T; Branigan, Patrick; Stojmirovic, Aleksandar; Perrigoue, Jacqueline; Brodmerkel, Carrie; Curran, Mark; Friedman, Joshua R; Hart, Amy; Lamousé-Smith, Esi; Wehkamp, Jan; Mehandru, Saurabh; Schadt, Eric E; Sands, Bruce E; Dubinsky, Marla C; Colombel, Jean-Frederic; Kasarskis, Andrew; Suárez-Fariñas, Mayte.

Gut ; 72(7): 1271-1287, 2023 07.

Article in English | MEDLINE | ID: mdl-36109152

14.

New Therapeutics for Ulcerative Colitis.

Hirten, Robert P; Sands, Bruce E.

Annu Rev Med ; 72: 199-213, 2021 01 27.

Article in English | MEDLINE | ID: mdl-33502898

15.

Ustekinumab versus adalimumab for induction and maintenance therapy in biologic-naive patients with moderately to severely active Crohn's disease: a multicentre, randomised, double-blind, parallel-group, phase 3b trial.

Sands, Bruce E; Irving, Peter M; Hoops, Timothy; Izanec, James L; Gao, Long-Long; Gasink, Christopher; Greenspan, Andrew; Allez, Matthieu; Danese, Silvio; Hanauer, Stephen B; Jairath, Vipul; Kuehbacher, Tanja; Lewis, James D; Loftus, Edward V; Mihaly, Emese; Panaccione, Remo; Scherl, Ellen; Shchukina, Oksana B; Sandborn, William J.

Lancet ; 399(10342): 2200-2211, 2022 06 11.

Article in English | MEDLINE | ID: mdl-35691323

16.

Prognostic Value of Fecal Calprotectin to Inform Treat-to-Target Monitoring in Ulcerative Colitis.

Dulai, Parambir S; Feagan, Brian G; Sands, Bruce E; Chen, Jingjing; Lasch, Karen; Lirio, Richard A.

Clin Gastroenterol Hepatol ; 21(2): 456-466.e7, 2023 02.

Article in English | MEDLINE | ID: mdl-35934286

17.

Vedolizumab, Adalimumab, and Methotrexate Combination Therapy in Crohn's Disease (EXPLORER).

Colombel, Jean-Frederic; Ungaro, Ryan C; Sands, Bruce E; Siegel, Corey A; Wolf, Douglas C; Valentine, John F; Feagan, Brian G; Neustifter, Blue; Kadali, Harisha; Nazarey, Pradeep; James, Alexandra; Jairath, Vipul; Qasim Khan, Rana M.

Clin Gastroenterol Hepatol ; 2023 Sep 22.

Article in English | MEDLINE | ID: mdl-37743037

18.

Efficacy and Safety of Mirikizumab in a Randomized Phase 2 Study of Patients With Crohn's Disease.

Sands, Bruce E; Peyrin-Biroulet, Laurent; Kierkus, Jaroslaw; Higgins, Peter D R; Fischer, Monika; Jairath, Vipul; Hirai, Fumihito; D'Haens, Geert; Belin, Ruth M; Miller, Debra; Gomez-Valderas, Elisa; Naegeli, April N; Tuttle, Jay L; Pollack, Paul F; Sandborn, William J.

Gastroenterology ; 162(2): 495-508, 2022 02.

Article in English | MEDLINE | ID: mdl-34748774

19.

Reliability and Responsiveness of Histologic Indices for the Assessment of Crohn's Disease Activity.

Solitano, Virginia; Schaeffer, David F; Hogan, Malcolm; Vande Casteele, Niels; Pai, Rish K; Zou, Guangyong; Pai, Reetesh K; Parker, Claire E; Rémillard, Julie; Christensen, Britt; Danese, Silvio; Peyrin-Biroulet, Laurent; Panaccione, Remo; Sands, Bruce E; D'Haens, Geert; Feagan, Brian G; Ma, Christopher; Jairath, Vipul.

Clin Gastroenterol Hepatol ; 2023 Dec 04.

Article in English | MEDLINE | ID: mdl-38056798

20.

Prospective Cohort Study to Investigate the Safety of Preoperative Tumor Necrosis Factor Inhibitor Exposure in Patients With Inflammatory Bowel Disease Undergoing Intra-abdominal Surgery.

Cohen, Benjamin L; Fleshner, Phillip; Kane, Sunanda V; Herfarth, Hans H; Palekar, Nicole; Farraye, Francis A; Leighton, Jonathan A; Katz, Jeffry A; Cohen, Russell D; Gerich, Mark E; Cross, Raymond K; Higgins, Peter D R; Tinsley, Andrew; Glover, Sarah; Siegel, Corey A; Bohl, Jaime L; Iskandar, Heba; Ji, Jiayi; Hu, Liangyuan; Sands, Bruce E.

Gastroenterology ; 163(1): 204-221, 2022 07.

Article in English | MEDLINE | ID: mdl-35413359

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