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Experientia
; 39(1): 119-21, 1983 Jan 15.
Article
in English
| MEDLINE
| ID: mdl-6825773
ABSTRACT
We have studied the elimination kinetics of iopamidol employing radioactivation and radiochemical separation. This method offers the advantage of guaranteeing absolutely no interference by radiation with tissue distribution or elimination kinetics of the analyzed compound. Our results show that iopamidol does not cross the blood-brain barrier, has no effect on thyroid iodine uptake and does not accumulate in the liver.
Subject(s)
Iothalamic Acid/analogs & derivatives , Animals , Brain/metabolism , Contrast Media , Iodine/blood , Iodine/metabolism , Iopamidol , Iothalamic Acid/metabolism , Kidney/metabolism , Kinetics , Liver/metabolism , Radiochemistry , Rats , Rats, Inbred Strains , Solubility , Thyroid Gland/metabolism , Water
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J Clin Psychopharmacol
; 14(6): 424-5, 1994 Dec.
Article
in English
| MEDLINE
| ID: mdl-7884024
Subject(s)
Cyproheptadine/therapeutic use , Depressive Disorder/drug therapy , Fluoxetine/therapeutic use , Schizophrenia/drug therapy , Schizophrenic Psychology , Adult , Aged , Antipsychotic Agents/adverse effects , Antipsychotic Agents/therapeutic use , Chronic Disease , Cyproheptadine/adverse effects , Depressive Disorder/psychology , Drug Therapy, Combination , Fluoxetine/adverse effects , Humans , Male , Middle Aged , Psychiatric Status Rating Scales
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