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1.
Bridging the Gap between Food Effects under Clinical Trial Conditions and Real Life: Modeling Delayed Gastric Emptying of Drug Substances and Gastric Content Volume Based on Meal Characteristics.
Mol Pharm
; 20(2): 1039-1049, 2023 02 06.
Article
in English
| MEDLINE | ID: mdl-36548544
2.
Application of the GastroDuo as an in Vitro Dissolution Tool To Simulate the Gastric Emptying of the Postprandial Stomach.
Mol Pharm
; 16(11): 4651-4660, 2019 11 04.
Article
in English
| MEDLINE | ID: mdl-31593480
3.
Predicting gastric emptying of drug substances taken under postprandial conditions by combination of biorelevant dissolution and mechanistic in silico modeling.
Eur J Pharm Sci
; 198: 106788, 2024 Jul 01.
Article
in English
| MEDLINE | ID: mdl-38705421
4.
Investigation of real-life drug intake behaviour in older adults and geriatric patients in Northern Germany - A biopharmaceutical perspective.
Eur J Pharm Sci
; 200: 106814, 2024 May 28.
Article
in English
| MEDLINE | ID: mdl-38815699
5.
Prolongation of the gastric residence time of caffeine after administration in fed state: Comparison of effervescent granules with an extended release tablet.
Eur J Pharm Biopharm
; 199: 114313, 2024 Jun.
Article
in English
| MEDLINE | ID: mdl-38718842
6.
Influence of Different Diets on the Degradation of Sulfasalazine by Colon Bacteria Determined Using MimiCol3.
Pharmaceuticals (Basel)
; 16(8)2023 Aug 10.
Article
in English
| MEDLINE | ID: mdl-37631043
7.
High-Dose Spermidine Supplementation Does Not Increase Spermidine Levels in Blood Plasma and Saliva of Healthy Adults: A Randomized Placebo-Controlled Pharmacokinetic and Metabolomic Study.
Nutrients
; 15(8)2023 Apr 12.
Article
in English
| MEDLINE | ID: mdl-37111071
8.
Intragastric Carbon Dioxide Release Prolongs the Gastric Residence Time of Postprandially Administered Caffeine.
Pharmaceutics
; 15(3)2023 Mar 22.
Article
in English
| MEDLINE | ID: mdl-36986872
9.
Determination of Gastric Water Emptying in Fasted and Fed State Conditions Using a Compression-Coated Tablet and Salivary Caffeine Kinetics.
Pharmaceutics
; 15(11)2023 Nov 04.
Article
in English
| MEDLINE | ID: mdl-38004563
10.
An Advanced Bioreactor Simulating Dynamic Physiological Conditions in the Human Ascending Colon: MimiCol3.
Pharmaceutics
; 14(5)2022 May 13.
Article
in English
| MEDLINE | ID: mdl-35631635
11.
Application of In Vivo Imaging Techniques and Diagnostic Tools in Oral Drug Delivery Research.
Pharmaceutics
; 14(4)2022 Apr 06.
Article
in English
| MEDLINE | ID: mdl-35456635
12.
Integration of advanced methods and models to study drug absorption and related processes: An UNGAP perspective.
Eur J Pharm Sci
; 172: 106100, 2022 May 01.
Article
in English
| MEDLINE | ID: mdl-34936937
13.
Mimicking the dynamic Colonic microbiota in vitro to gain a better understanding on the in vivo metabolism of xenobiotics: Degradation of sulfasalazine.
Int J Pharm
; 603: 120704, 2021 Jun 15.
Article
in English
| MEDLINE | ID: mdl-33991596
14.
Design and Optimization of a Novel Strategy for the Local Treatment of Helicobacter pylori Infections.
J Pharm Sci
; 110(3): 1302-1309, 2021 03.
Article
in English
| MEDLINE | ID: mdl-33253724
15.
Application of the GastroDuo to study the interplay of drug release and gastric emptying in case of immediate release Aspirin formulations.
Eur J Pharm Biopharm
; 151: 9-17, 2020 Jun.
Article
in English
| MEDLINE | ID: mdl-32268191
16.
Comparison of In Vitro and In Vivo Results Using the GastroDuo and the Salivary Tracer Technique: Immediate Release Dosage Forms under Fasting Conditions.
Pharmaceutics
; 11(12)2019 Dec 07.
Article
in English
| MEDLINE | ID: mdl-31817867
17.
In vivo characterization of enTRinsic™ drug delivery technology capsule after intake in fed state: A cross-validation approach using salivary tracer technique in comparison to MRI.
J Control Release
; 313: 24-32, 2019 11 10.
Article
in English
| MEDLINE | ID: mdl-31626859
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