Search | VHL Search Portal

1.

BRD4 inhibition sensitizes diffuse large B-cell lymphoma cells to ferroptosis.

Schmitt, Anja; Grimm, Melanie; Kreienkamp, Nina; Junge, Hannah; Labisch, Jan; Schuhknecht, Laurentz; Schönfeld, Caroline; Görsch, Elsa; Tibello, Alessia; Menck, Kerstin; Bleckmann, Annalen; Lengerke, Claudia; Rosenbauer, Frank; Grau, Michael; Zampieri, Mattia; Schulze-Osthoff, Klaus; Klener, Pavel; Dolnikova, Alexandra; Lenz, Georg; Hailfinger, Stephan.

Blood ; 142(13): 1143-1155, 2023 09 28.

Article in English | MEDLINE | ID: mdl-37294920

2.

Acidosis-mediated increase in IFN-Î³-induced PD-L1 expression on cancer cells as an immune escape mechanism in solid tumors.

Knopf, Philipp; Stowbur, Dimitri; Hoffmann, Sabrina H L; Hermann, Natalie; Maurer, Andreas; Bucher, Valentina; Poxleitner, Marilena; Tako, Bredi; Sonanini, Dominik; Krishnamachary, Balaji; Sinharay, Sanhita; Fehrenbacher, Birgit; Gonzalez-Menendez, Irene; Reckmann, Felix; Bomze, David; Flatz, Lukas; Kramer, Daniela; Schaller, Martin; Forchhammer, Stephan; Bhujwalla, Zaver M; Quintanilla-Martinez, Leticia; Schulze-Osthoff, Klaus; Pagel, Mark D; Fransen, Marieke F; Röcken, Martin; Martins, André F; Pichler, Bernd J; Ghoreschi, Kamran; Kneilling, Manfred.

Mol Cancer ; 22(1): 207, 2023 12 15.

Article in English | MEDLINE | ID: mdl-38102680

3.

Dimethyl fumarate induces ferroptosis and impairs NF-κB/STAT3 signaling in DLBCL.

Schmitt, Anja; Xu, Wendan; Bucher, Philip; Grimm, Melanie; Konantz, Martina; Horn, Heike; Zapukhlyak, Myroslav; Berning, Philipp; Brändle, Marc; Jarboui, Mohamed-Ali; Schönfeld, Caroline; Boldt, Karsten; Rosenwald, Andreas; Ott, German; Grau, Michael; Klener, Pavel; Vockova, Petra; Lengerke, Claudia; Lenz, Georg; Schulze-Osthoff, Klaus; Hailfinger, Stephan.

Blood ; 138(10): 871-884, 2021 09 09.

Article in English | MEDLINE | ID: mdl-33876201

4.

Hepatokine-based identification of fibrotic NASH and improved risk stratification in a multicentre cohort of NAFLD patients.

Franck, Martin; John, Katharina; Al Aoua, Sherin; Rau, Monika; Geier, Andreas; Schattenberg, Jörn M; Wedemeyer, Heiner; Schulze-Osthoff, Klaus; Bantel, Heike.

Liver Int ; 43(12): 2668-2679, 2023 12.

Article in English | MEDLINE | ID: mdl-37534777

5.

Profile of the multicenter cohort of the German Cancer Consortium's Clinical Communication Platform.

Maier, Daniel; Vehreschild, Jörg Janne; Uhl, Barbara; Meyer, Sandra; Berger-Thürmel, Karin; Boerries, Melanie; Braren, Rickmer; Grünwald, Viktor; Hadaschik, Boris; Palm, Stefan; Singer, Susanne; Stuschke, Martin; Juárez, David; Delpy, Pierre; Lambarki, Mohamed; Hummel, Michael; Engels, Cäcilia; Andreas, Stefanie; Gökbuget, Nicola; Ihrig, Kristina; Burock, Susen; Keune, Dietmar; Eggert, Angelika; Keilholz, Ulrich; Schulz, Hagen; Büttner, Daniel; Löck, Steffen; Krause, Mechthild; Esins, Mirko; Ressing, Frank; Schuler, Martin; Brandts, Christian; Brucker, Daniel P; Husmann, Gabriele; Oellerich, Thomas; Metzger, Patrick; Voigt, Frederik; Illert, Anna L; Theobald, Matthias; Kindler, Thomas; Sudhof, Ursula; Reckmann, Achim; Schwinghammer, Felix; Nasseh, Daniel; Weichert, Wilko; von Bergwelt-Baildon, Michael; Bitzer, Michael; Malek, Nisar; Öner, Öznur; Schulze-Osthoff, Klaus.

Eur J Epidemiol ; 38(5): 573-586, 2023 May.

Article in English | MEDLINE | ID: mdl-37017830

6.

Targeting chronic NFAT activation with calcineurin inhibitors in diffuse large B-cell lymphoma.

Bucher, Philip; Erdmann, Tabea; Grondona, Paula; Xu, Wendan; Schmitt, Anja; Schürch, Christoph; Zapukhlyak, Myroslav; Schönfeld, Caroline; Serfling, Edgar; Kramer, Daniela; Grau, Michael; Klener, Pavel; Lengerke, Claudia; Schulze-Osthoff, Klaus; Lenz, Georg; Hailfinger, Stephan.

Blood ; 135(2): 121-132, 2020 01 09.

Article in English | MEDLINE | ID: mdl-31794606

7.

Human invariant natural killer T cells promote tolerance by preferential apoptosis induction of conventional dendritic cells.

Schmid, Hannes; Ribeiro, Emmanuelle M; Secker, Kathy-Ann; Duerr-Stoerzer, Silke; Keppeler, Hildegard; Dong, Ruoyun; Munz, Timo; Schulze-Osthoff, Klaus; Hailfinger, Stephan; Schneidawind, Corina; Schneidawind, Dominik.

Haematologica ; 107(2): 427-436, 2022 02 01.

Article in English | MEDLINE | ID: mdl-33440919

8.

Bcl-x_L as prognostic marker and potential therapeutic target in cholangiocarcinoma.

Hoffmeister-Wittmann, Paula; Mock, Andreas; Nichetti, Federico; Korell, Felix; Heilig, Christoph E; Scherr, Anna-Lena; Günther, Michael; Albrecht, Thomas; Kelmendi, Eblina; Xu, Kaiyu; Nader, Luisa; Kessler, Annika; Schmitt, Nathalie; Fritzsche, Sarah; Weiler, Sofia; Sobol, Benjamin; Stenzinger, Albrecht; Boeck, Stefan; Westphalen, Christoph B; Schulze-Osthoff, Klaus; Trojan, Jörg; Kindler, Thomas; Weichert, Wilko; Spiekermann, Karsten; Bitzer, Michael; Folprecht, Gunnar; Illert, Anna L; Boerries, Melanie; Klauschen, Frederick; Ochsenreither, Sebastian; Siveke, Jens; Bauer, Sebastian; Glimm, Hanno; Brors, Benedikt; Hüllein, Jennifer; Hübschmann, Daniel; Uhrig, Sebastian; Horak, Peter; Kreutzfeldt, Simon; Banales, Jesus M; Springfeld, Christoph; Jäger, Dirk; Schirmacher, Peter; Roessler, Stephanie; Ormanns, Steffen; Goeppert, Benjamin; Fröhling, Stefan; Köhler, Bruno C.

Liver Int ; 42(12): 2855-2870, 2022 12.

Article in English | MEDLINE | ID: mdl-35983950

9.

The paracaspase MALT1 in psoriasis.

Hailfinger, Stephan; Schulze-Osthoff, Klaus.

Biol Chem ; 402(12): 1583-1589, 2021 11 25.

Article in English | MEDLINE | ID: mdl-34192836

10.

IκB(NS) protein mediates regulatory T cell development via induction of the Foxp3 transcription factor.

Schuster, Marc; Glauben, Rainer; Plaza-Sirvent, Carlos; Schreiber, Lisa; Annemann, Michaela; Floess, Stefan; Kühl, Anja A; Clayton, Linda K; Sparwasser, Tim; Schulze-Osthoff, Klaus; Pfeffer, Klaus; Huehn, Jochen; Siegmund, Britta; Schmitz, Ingo.

Immunity ; 37(6): 998-1008, 2012 Dec 14.

Article in English | MEDLINE | ID: mdl-23200824

11.

IkBÎ¶ is a Key Regulator of Tumour Necrosis Factor-a and Interleukin-17A-mediated Induction of Interleukin-36g in Human Keratinocytes.

Ovesen, Sofie Kaas; Schulze-Osthoff, Klaus; Iversen, Lars; Johansen, Claus.

Acta Derm Venereol ; 101(2): adv00386, 2021 Feb 09.

Article in English | MEDLINE | ID: mdl-33491092

12.

IκBÎ¶ is a key transcriptional regulator of IL-36-driven psoriasis-related gene expression in keratinocytes.

Müller, Anne; Hennig, André; Lorscheid, Sebastian; Grondona, Paula; Schulze-Osthoff, Klaus; Hailfinger, Stephan; Kramer, Daniela.

Proc Natl Acad Sci U S A ; 115(40): 10088-10093, 2018 10 02.

Article in English | MEDLINE | ID: mdl-30224457

13.

Distinct immune evasion in APOBEC-enriched, HPV-negative HNSCC.

Messerschmidt, Clemens; Obermayer, Benedikt; Klinghammer, Konrad; Ochsenreither, Sebastian; Treue, Denise; Stenzinger, Albrecht; Glimm, Hanno; Fröhling, Stefan; Kindler, Thomas; Brandts, Christian H; Schulze-Osthoff, Klaus; Weichert, Wilko; Tinhofer, Ingeborg; Klauschen, Frederick; Keilholz, Ulrich; Beule, Dieter; Rieke, Damian T.

Int J Cancer ; 147(8): 2293-2302, 2020 10 15.

Article in English | MEDLINE | ID: mdl-32468570

14.

Autophagy alleviates amiodarone-induced hepatotoxicity.

Wandrer, Franziska; Frangez, Ziva; Liebig, Stephanie; John, Katharina; Vondran, Florian; Wedemeyer, Heiner; Veltmann, Christian; Pfeffer, Tobias J; Shibolet, Oren; Schulze-Osthoff, Klaus; Simon, Hans-Uwe; Bantel, Heike.

Arch Toxicol ; 94(10): 3527-3539, 2020 10.

Article in English | MEDLINE | ID: mdl-32651653

15.

T-helper-1-cell cytokines drive cancer into senescence.

Braumüller, Heidi; Wieder, Thomas; Brenner, Ellen; Aßmann, Sonja; Hahn, Matthias; Alkhaled, Mohammed; Schilbach, Karin; Essmann, Frank; Kneilling, Manfred; Griessinger, Christoph; Ranta, Felicia; Ullrich, Susanne; Mocikat, Ralph; Braungart, Kilian; Mehra, Tarun; Fehrenbacher, Birgit; Berdel, Julia; Niessner, Heike; Meier, Friedegund; van den Broek, Maries; Häring, Hans-Ulrich; Handgretinger, Rupert; Quintanilla-Martinez, Leticia; Fend, Falko; Pesic, Marina; Bauer, Jürgen; Zender, Lars; Schaller, Martin; Schulze-Osthoff, Klaus; Röcken, Martin.

Nature ; 494(7437): 361-5, 2013 Feb 21.

Article in English | MEDLINE | ID: mdl-23376950

16.

Bax/Bak-independent mitochondrial depolarization and reactive oxygen species induction by sorafenib overcome resistance to apoptosis in renal cell carcinoma.

Gillissen, Bernhard; Richter, Anja; Richter, Antje; Preissner, Robert; Schulze-Osthoff, Klaus; Essmann, Frank; Daniel, Peter T.

J Biol Chem ; 292(16): 6478-6492, 2017 04 21.

Article in English | MEDLINE | ID: mdl-28154184

17.

Non-invasive tests for evaluating treatment response in NAFLD.

Bantel, Heike; Schulze-Osthoff, Klaus.

J Hepatol ; 78(3): e101-e102, 2023 03.

Article in English | MEDLINE | ID: mdl-36007707

18.

Bok is a genuine multi-BH-domain protein that triggers apoptosis in the absence of Bax and Bak.

Einsele-Scholz, Stephanie; Malmsheimer, Silke; Bertram, Katrin; Stehle, Daniel; Johänning, Janina; Manz, Marianne; Daniel, Peter T; Gillissen, Bernhard F; Schulze-Osthoff, Klaus; Essmann, Frank.

J Cell Sci ; 129(11): 2213-23, 2016 06 01.

Article in English | MEDLINE | ID: mdl-27076518

19.

IκBÎ¶ is a key driver in the development of psoriasis.

Johansen, Claus; Mose, Maike; Ommen, Pernille; Bertelsen, Trine; Vinter, Hanne; Hailfinger, Stephan; Lorscheid, Sebastian; Schulze-Osthoff, Klaus; Iversen, Lars.

Proc Natl Acad Sci U S A ; 112(43): E5825-33, 2015 Oct 27.

Article in English | MEDLINE | ID: mdl-26460049

20.

The Atypical Inhibitor of NF-κB, IκBÎ¶, Controls Macrophage Interleukin-10 Expression.

Hörber, Sebastian; Hildebrand, Dominic G; Lieb, Wolfgang S; Lorscheid, Sebastian; Hailfinger, Stephan; Schulze-Osthoff, Klaus; Essmann, Frank.

J Biol Chem ; 291(24): 12851-12861, 2016 Jun 10.

Article in English | MEDLINE | ID: mdl-27129283

VHL Search Portal

Information and Knowledge for Health

Config filters

Your selection (0)

Export format:

Export: