ABSTRACT
The prevalence of amyloidosis has been increasing, driven by a combination of improved awareness, evolution of diagnostic pathways, and effective treatment options for both transthyretin and light chain amyloidosis. Due to the complexity of amyloidosis, centralised expert providers with experience in delineating the nuances of confirmatory diagnosis and management may be beneficial. There are many potential benefits of a centre of excellence designation for the treatment of amyloidosis including recognition of institutions that have been leading the way for the optimal treatment of this condition, establishing the expectations for any centre who is engaging in the treatment of amyloidosis and developing cooperative groups to allow more effective research in this disease space. Standardising the expectations and criteria for these centres is essential for ensuring the highest quality of clinical care and community education. In order to define what components are necessary for an effective centre of excellence for the treatment of amyloidosis, we prepared a survey in cooperation with a multidisciplinary panel of amyloidosis experts representing an international consortium. The purpose of this position statement is to identify the essential elements necessary for highly effective clinical care and to develop a general standard with which practices or institutions could be recognised as a centre of excellence.
Subject(s)
Amyloidosis , Humans , Amyloidosis/therapy , Amyloidosis/diagnosis , Cardiomyopathies/therapy , Cardiomyopathies/diagnosis , Cardiology/standards , Societies, Medical , Medical Oncology/standards , Cardio-OncologyABSTRACT
A cardiomiopatia hipertrófica (CMH) é uma doença genética cardíaca, caracterizada por hipertrofia ventricular esquerda. É assimétrica na maioria das vezes. O método diagnóstico considerado padrão para detecção de CMH é o ecocardiograma bidimensional. Os casos de CMH que passam despercebidos por esse método são poucos, e para eles há a necessidade de um outro exame de imagem que melhor visualize o tipo morfológico da doença apresentada: a ressonância magnética cardíaca (RMC). Este relato descreve um paciente com alterações eletrocardiográficas de base e que foi diagnosticado com CMH apical unicamente pela RMC, sem apresentar anormalidade significativa à ecocardiografia convencional.