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1.
Rebound growth of BRAF mutant pediatric glioma cells after MAPKi withdrawal is associated with MAPK reactivation and secretion of microglia-recruiting cytokines.
J Neurooncol
; 2024 Apr 17.
Article
in English
| MEDLINE | ID: mdl-38630384
2.
DNA methylation-based classification of central nervous system tumours.
Nature
; 555(7697): 469-474, 2018 03 22.
Article
in English
| MEDLINE | ID: mdl-29539639
3.
Integrative multi-omics reveals two biologically distinct groups of pilocytic astrocytoma.
Acta Neuropathol
; 146(4): 551-564, 2023 10.
Article
in English
| MEDLINE | ID: mdl-37656187
4.
Identification of low and very high-risk patients with non-WNT/non-SHH medulloblastoma by improved clinico-molecular stratification of the HIT2000 and I-HIT-MED cohorts.
Acta Neuropathol
; 145(1): 97-112, 2023 01.
Article
in English
| MEDLINE | ID: mdl-36459208
5.
Amplification of the PLAG-family genes-PLAGL1 and PLAGL2-is a key feature of the novel tumor type CNS embryonal tumor with PLAGL amplification.
Acta Neuropathol
; 145(1): 49-69, 2023 01.
Article
in English
| MEDLINE | ID: mdl-36437415
6.
Glioneuronal tumor with ATRX alteration, kinase fusion and anaplastic features (GTAKA): a molecularly distinct brain tumor type with recurrent NTRK gene fusions.
Acta Neuropathol
; 145(5): 667-680, 2023 05.
Article
in English
| MEDLINE | ID: mdl-36933012
7.
Generation of patient-derived pediatric pilocytic astrocytoma in-vitro models using SV40 large T: evaluation of a modeling workflow.
J Neurooncol
; 165(3): 467-478, 2023 Dec.
Article
in English
| MEDLINE | ID: mdl-37999877
8.
Class I HDAC inhibitor entinostat synergizes with PLK1 inhibitors in MYC-amplified medulloblastoma cells.
J Neurooncol
; 163(1): 143-158, 2023 May.
Article
in English
| MEDLINE | ID: mdl-37183219
9.
Accurate calling of KIAA1549-BRAF fusions from DNA of human brain tumours using methylation array-based copy number and gene panel sequencing data.
Neuropathol Appl Neurobiol
; 47(3): 406-414, 2021 04.
Article
in English
| MEDLINE | ID: mdl-33336421
10.
Response to trametinib treatment in progressive pediatric low-grade glioma patients.
J Neurooncol
; 149(3): 499-510, 2020 Sep.
Article
in English
| MEDLINE | ID: mdl-33026636
11.
Correction to: Amplification of the PLAG-family genes-PLAGL1 and PLAGL2-is a key feature of the novel tumor type CNS embryonal tumor with PLAGL amplification.
Acta Neuropathol
; 145(4): 511-514, 2023 Apr.
Article
in English
| MEDLINE | ID: mdl-36786841
12.
Response in a child with a BRAF V600E mutated desmoplastic infantile astrocytoma upon retreatment with vemurafenib.
Pediatr Blood Cancer
; 65(3)2018 03.
Article
in English
| MEDLINE | ID: mdl-29230924
13.
Molecular Diagnostics in Pediatric Brain Tumors: Impact on Diagnosis and Clinical Decision-Making - A Selected Case Series.
Klin Padiatr
; 230(6): 305-313, 2018 Oct.
Article
in English
| MEDLINE | ID: mdl-29996150
14.
Next-generation sequencing in routine brain tumor diagnostics enables an integrated diagnosis and identifies actionable targets.
Acta Neuropathol
; 131(6): 903-10, 2016 06.
Article
in English
| MEDLINE | ID: mdl-26671409
15.
GOPC:ROS1 and other ROS1 fusions represent a rare but recurrent drug target in a variety of glioma types.
Acta Neuropathol
; 142(6): 1065-1069, 2021 12.
Article
in English
| MEDLINE | ID: mdl-34536122
16.
Molecular diagnostics enables detection of actionable targets: the Pediatric Targeted Therapy 2.0 registry.
Eur J Cancer
; 180: 71-84, 2023 02.
Article
in English
| MEDLINE | ID: mdl-36542877
17.
The first-in-class ERK inhibitor ulixertinib shows promising activity in mitogen-activated protein kinase (MAPK)-driven pediatric low-grade glioma models.
Neuro Oncol
; 25(3): 566-579, 2023 03 14.
Article
in English
| MEDLINE | ID: mdl-35882450
18.
BH3 mimetics targeting BCL-XL impact the senescent compartment of pilocytic astrocytoma.
Neuro Oncol
; 25(4): 735-747, 2023 04 06.
Article
in English
| MEDLINE | ID: mdl-35977048
19.
MAPK inhibitor sensitivity scores predict sensitivity driven by the immune infiltration in pediatric low-grade gliomas.
Nat Commun
; 14(1): 4533, 2023 07 27.
Article
in English
| MEDLINE | ID: mdl-37500667
20.
Clinical outcome of pediatric medulloblastoma patients with Li-Fraumeni syndrome.
Neuro Oncol
; 25(12): 2273-2286, 2023 12 08.
Article
in English
| MEDLINE | ID: mdl-37379234