ABSTRACT
The prevalence of child and adolescent growth and mental-behavior related diseases are increasing,and the pathogcnesis are complex.Twins are excellent natural resources for complex chronic diseases research as they share the maternal intrauterine environment,born at the same time and share the same family environment in early years,which could benefit the adjust ment of confounding factors,such as age,genetic factors and early family environmental factors.Birth cohort with twin families involved could be more effective in exploring the genetic and environmental factors for complex chronic diseases at the very beginning of life.This paper summarizes the objective,content,progress,strengths and potential problems of Wuhan Twin Birth Cohort,with emphasis on the overall design and progress of the study.
ABSTRACT
The prevalence of child and adolescent growth and mental-behavior related diseases are increasing, and the pathogenesis are complex. Twins are excellent natural resources for complex chronic diseases research as they share the maternal intrauterine environment, born at the same time and share the same family environment in early years, which could benefit the adjust ment of confounding factors, such as age, genetic factors and early family environmental factors. Birth cohort with twin families involved could be more effective in exploring the genetic and environmental factors for complex chronic diseases at the very beginning of life. This paper summarizes the objective, content, progress, strengths and potential problems of Wuhan Twin Birth Cohort, with emphasis on the overall design and progress of the study.
Subject(s)
Adolescent , Child , Female , Humans , Male , Asian People , Birth Weight , China , Cohort Studies , Diseases in Twins/genetics , Epidemiological Monitoring , Twin Studies as Topic , TwinsABSTRACT
<p><b>OBJECTIVE</b>To study the mathematical model of optimum fertilizer application to Pinellia by field experiments.</p><p><b>METHOD</b>Three factors and 5 levels quadratic rotational combination design was applied to study the effects of N, P and K.</p><p><b>RESULT AND CONCLUSION</b>N, P and K combination application can achieve the maximum yield of 29,921.4 kg x hm(-2), the amount of N, P2O5, K2O were 413.79, 224.79, 164.01 kg x hm(-2), respectively. The effects of the 3 factors were in following orders: P > N > K.</p>