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1.

Long-term hematopoietic transfer of the anti-cancer and lifespan-extending capabilities of a genetically engineered blood system by transplantation of bone marrow mononuclear cells.

Wang, Jing-Ping; Hung, Chun-Hao; Liou, Yae-Huei; Liu, Ching-Chen; Yeh, Kun-Hai; Wang, Keh-Yang; Lai, Zheng-Sheng; Chatterjee, Biswanath; Hsu, Tzu-Chi; Lee, Tung-Liang; Shyu, Yu-Chiau; Hsiao, Pei-Wen; Chen, Liuh-Yow; Chuang, Trees-Juen; Yu, Chen-Hsin Albert; Liao, Nan-Shih; Shen, C-K James.

Elife ; 122024 May 16.

Article in English | MEDLINE | ID: mdl-38752723

2.

Targeted depletion of TDP-43 expression in the spinal cord motor neurons leads to the development of amyotrophic lateral sclerosis-like phenotypes in mice.

Wu, Lien-Szu; Cheng, Wei-Cheng; Shen, C-K James.

J Biol Chem ; 287(33): 27335-44, 2012 Aug 10.

Article in English | MEDLINE | ID: mdl-22718760

3.

Regulation of autophagy by neuropathological protein TDP-43.

Bose, Jayarama Krishnan; Huang, Chi-Chen; Shen, C-K James.

J Biol Chem ; 286(52): 44441-8, 2011 Dec 30.

Article in English | MEDLINE | ID: mdl-22052911

4.

Developmental silencing of human zeta-globin gene expression is mediated by the transcriptional repressor RREB1.

Chen, Ruei-Lin; Chou, Yu-Chi; Lan, Yii-Jenq; Huang, Ting-Shuo; Shen, C-K James.

J Biol Chem ; 285(14): 10189-97, 2010 Apr 02.

Article in English | MEDLINE | ID: mdl-20133935

5.

TDP-43, a neuro-pathosignature factor, is essential for early mouse embryogenesis.

Wu, Lien-Szu; Cheng, Wei-Cheng; Hou, Shin-Chen; Yan, Yu-Ting; Jiang, Si-Tse; Shen, C-K James.

Genesis ; 48(1): 56-62, 2010 Jan.

Article in English | MEDLINE | ID: mdl-20014337

6.

Rate of evolution in brain-expressed genes in humans and other primates.

Wang, Hurng-Yi; Chien, Huan-Chieh; Osada, Naoki; Hashimoto, Katsuyuki; Sugano, Sumio; Gojobori, Takashi; Chou, Chen-Kung; Tsai, Shih-Feng; Wu, Chung-I; Shen, C-K James.

PLoS Biol ; 5(2): e13, 2007 Feb.

Article in English | MEDLINE | ID: mdl-17194215

7.

Cytosolic calcium regulates cytoplasmic accumulation of TDP-43 through Calpain-A and Importin α3.

Park, Jeong Hyang; Chung, Chang Geon; Park, Sung Soon; Lee, Davin; Kim, Kyung Min; Jeong, Yeonjin; Kim, Eun Seon; Cho, Jae Ho; Jeon, Yu-Mi; Shen, C-K James; Kim, Hyung-Jun; Hwang, Daehee; Lee, Sung Bae.

Elife ; 92020 12 11.

Article in English | MEDLINE | ID: mdl-33305734

8.

TDP-43: an emerging new player in neurodegenerative diseases.

Wang, I-Fan; Wu, Lien-Szu; Shen, C-K James.

Trends Mol Med ; 14(11): 479-85, 2008 Nov.

Article in English | MEDLINE | ID: mdl-18929508

9.

Transcriptomopathies of pre- and post-symptomatic frontotemporal dementia-like mice with TDP-43 depletion in forebrain neurons.

Wu, Lien-Szu; Cheng, Wei-Cheng; Chen, Chia-Ying; Wu, Ming-Che; Wang, Yi-Chi; Tseng, Yu-Hsiang; Chuang, Trees-Juen; Shen, C-K James.

Acta Neuropathol Commun ; 7(1): 50, 2019 03 29.

Article in English | MEDLINE | ID: mdl-30922385

10.

TDP-43, the signature protein of FTLD-U, is a neuronal activity-responsive factor.

Wang, I-Fan; Wu, Lien-Szn; Chang, Hsiang-Yu; Shen, C-K James.

J Neurochem ; 105(3): 797-806, 2008 May.

Article in English | MEDLINE | ID: mdl-18088371

11.

Sumoylation of p45/NF-E2: nuclear positioning and transcriptional activation of the mammalian beta-like globin gene locus.

Shyu, Yu-Chiau; Lee, Tung-Liang; Ting, Chun-Yuan; Wen, Shau-Ching; Hsieh, Lie-Jiau; Li, Yueh-Chun; Hwang, Jau-Lang; Lin, Chyi-Chyang; Shen, C-K James.

Mol Cell Biol ; 25(23): 10365-78, 2005 Dec.

Article in English | MEDLINE | ID: mdl-16287851

12.

H3K9 histone methyltransferase, KMT1E/SETDB1, cooperates with the SMAD2/3 pathway to suppress lung cancer metastasis.

Wu, Pei-Chun; Lu, Jeng-Wei; Yang, Jer-Yen; Lin, I-Hsuan; Ou, Da-Liang; Lin, Yu-Hsiang; Chou, Kuan-Hsien; Huang, Wen-Feng; Wang, Wan-Ping; Huang, Yih-Leh; Hsu, Chiun; Lin, Liang-In; Lin, Yueh-Min; Shen, C-K James; Tzeng, Tsai-Yu.

Cancer Res ; 74(24): 7333-43, 2014 Dec 15.

Article in English | MEDLINE | ID: mdl-25477335

13.

Neuronal function and dysfunction of Drosophila dTDP.

Lin, Meng-Jau; Cheng, Ching-Wei; Shen, C-K James.

PLoS One ; 6(6): e20371, 2011.

Article in English | MEDLINE | ID: mdl-21673800

14.

Ankrd17, an ubiquitously expressed ankyrin factor, is essential for the vascular integrity during embryogenesis.

Hou, Shin-Chen; Chan, Li-Wei; Chou, Yu-Chi; Su, Ching-Yuan; Chen, Xin; Shih, Yen-Ling; Tsai, Pei-Chun; Shen, C-K James; Yan, Yu-Ting.

FEBS Lett ; 583(17): 2765-71, 2009 Sep 03.

Article in English | MEDLINE | ID: mdl-19619540

15.

TDP-43 overexpression enhances exon 7 inclusion during the survival of motor neuron pre-mRNA splicing.

Bose, Jayarama Krishnan; Wang, I-Fan; Hung, Li; Tarn, Woan-Yuh; Shen, C-K James.

J Biol Chem ; 283(43): 28852-9, 2008 Oct 24.

Article in English | MEDLINE | ID: mdl-18703504

16.

Epigenetic regulation of the Drosophila chromosome 4 by the histone H3K9 methyltransferase dSETDB1.

Tzeng, Tsai-Yu; Lee, Chi-Hua; Chan, Li-Wei; Shen, C-K James.

Proc Natl Acad Sci U S A ; 104(31): 12691-6, 2007 Jul 31.

Article in English | MEDLINE | ID: mdl-17652514

17.

Actin-based modeling of a transcriptionally competent nuclear substructure induced by transcription inhibition.

Wang, I-Fan; Chang, Hsiang-Yu; Shen, C-K James.

Exp Cell Res ; 312(19): 3796-807, 2006 Nov 15.

Article in English | MEDLINE | ID: mdl-17022973

18.

DNA methyltransferase gene dDnmt2 and longevity of Drosophila.

Lin, Meng-Jau; Tang, Lin-Ya; Reddy, M Narsa; Shen, C-K James.

J Biol Chem ; 280(2): 861-4, 2005 Jan 14.

Article in English | MEDLINE | ID: mdl-15533947

19.

Substitution rate and structural divergence of 5'UTR evolution: comparative analysis between human and cynomolgus monkey cDNAs.

Osada, Naoki; Hirata, Makoto; Tanuma, Reiko; Kusuda, Jun; Hida, Munetomo; Suzuki, Yutaka; Sugano, Sumio; Gojobori, Takashi; Shen, C-K James; Wu, Chung-I; Hashimoto, Katsuyuki.

Mol Biol Evol ; 22(10): 1976-82, 2005 Oct.

Article in English | MEDLINE | ID: mdl-15944441

20.

Erythroid gene suppression by NF-kappa B.

Liu, Jan-Jan; Hou, Shin-Chen; Shen, C-K James.

J Biol Chem ; 278(21): 19534-40, 2003 May 23.

Article in English | MEDLINE | ID: mdl-12642582

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