Effects of probiotic yogurt consumption on lipid profile in type 2 diabetic patients: A randomized controlled clinical trial.

BACKGROUND: Alteration in plasma lipid and lipoprotein profile has been documented in diabetic patients. The purpose of this study was to compare the effect of probiotic and conventional yogurt on lipid profile in type 2 diabetes mellitus patients. MATERIALS AND METHODS: A total of 44 patients with type 2 diabetes aged 30-60 years old who had low density lipoprotein cholesterol (LDL-c) ≥100 mg/dl enrolled in this randomized, double - blind controlled trial and were assigned to two intervention and control groups. The subjects in the intervention group consumed 300 g/d probiotic yogurt containing Lactobacillus acidophilus La-5 and Bifidobacterium lactis Bb-12 and subjects in the control group consumed 300 g/d conventional yogurt for 8 weeks. Anthropometric indices, dietary intake, and serum lipid profile were evaluated at the beginning and end of the intervention. Independent-sample t-test, paired sample t-test, ANCOVA, and repeated measures were used for statistical analysis. RESULTS: The consumption of probiotic yogurt caused significant decrease in LDL-c/high density lipoprotein cholesterol (HDL-c) ratio (3.13 ± 1.00-2.07 ± 0.71, P = 0.016). The levels of HDL-c were increased significantly (43.66 ± 6.80-50.42 ± 6.64, P = 0.023) in the intervention group postintervention. However, there were no significant differences in triglyceride and total cholesterol levels between two groups postintervention (P < 0.05). CONCLUSION: It is suggested that probiotic yogurt consumption may be used as an alternative prevention approach and treatment method to improve dyslipidemia in patients with type 2 diabetes.

The effect of soy nut on serum total antioxidant, endothelial function and cardiovascular risk factors in patients with type 2 diabetes.

BACKGROUND: Type 2 diabetes has a high spread and growing process. Using appropriate food diets is among therapeutic approaches has been applied for diabetic patients. Soya utilization has shown effective results in controlling metabolic abnormalities of these patients. The aim of this study is to investigate the effects of soy nut on glycemic conditions, blood pressure, lipid profile, antioxidant effects and vascular endothelial function of these patients. METHODS: 70 patients with type 2 diabetes were randomly divided into two groups of the test (35 people) and control (35 people). The patients in the intervention group were subjected to 60 g soy nut diet as a part of daily protein for 8 weeks and the control group under the usual diet of diabetes. The fasting glucose, blood pressure, lipid profile, brachial blood flow, the level of serum E-Selectin and total antioxidant capacity in control and test group were assessed before and after diet. RESULTS: Consuming 60 g soy nut for 8 weeks significantly decreased the fasting blood glucose (P = 0.03), total serum cholesterol (P < 0.01), LDL-c (P = 0.01), and E-Selectin (P < 0.01) and increased the capacity of serum total antioxidants (P < 0.01), brachial blood flow (P < 0.01) but didn't have any significant effect on systolic/diastolic blood pressure, HDL-c, and TG. CONCLUSION: Soy nut utilization in the patients with type-2 diabetes can significantly improve the glycemic condition, increase brachial blood flow, decrease E-selectin (improvement of endothelial function), increase serum total antioxidants and lipid profile but has no significant effect on blood pressure and HDL-c.

Association of dietary patterns with body mass index, waist circumference, and blood pressure in an adult population in Ahvaz, Iran.

OBJECTIVES: To assess the association between dietary patterns, central obesity, and blood pressure (BP). METHODS: In this cross-sectional study, we evaluated anthropometric measurements, BP, and usual dietary intakes of 243 men, aged 30-50 years old, working at the Education and Culture Systems in Ahvaz, Iran, between October 2011 and March 2012 using the Food Frequency Questionnaire (FFQ). RESULTS: Using the factor analysis, we extracted 3 major dietary patterns: "prudent", "high protein" and "high fat". After controlling for confounders (energy and physical activity), "prudent" pattern scores were negatively associated with body mass index, waist circumference, waist-to-hip ratio, systolic and diastolic BP (p<0.05). Scores of "high protein" and "high fat" patterns were positively related to obesity and hypertension indices (p<0.05). CONCLUSION: A dietary pattern characterized by high consumption of vegetables, fruits, poultry, fish, low-fat dairy products, whole grains, nuts, and olives are associated with lower risk of central obesity and hypertension, while dietary patterns with high amounts of red meat, egg, butter, high fat dairy products, hydrogenated fats, pizza, and soft drinks are associated with increased risk of these conditions in Ahvaz, Iran.