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1.

RNA Repair: Hiding in Plain Sight.

Shuman, Stewart.

Annu Rev Genet ; 57: 461-489, 2023 11 27.

Article in English | MEDLINE | ID: mdl-37722686

2.

Structure-function analysis of STING activation by c[G(2',5')pA(3',5')p] and targeting by antiviral DMXAA.

Gao, Pu; Ascano, Manuel; Zillinger, Thomas; Wang, Weiyi; Dai, Peihong; Serganov, Artem A; Gaffney, Barbara L; Shuman, Stewart; Jones, Roger A; Deng, Liang; Hartmann, Gunther; Barchet, Winfried; Tuschl, Thomas; Patel, Dinshaw J.

Cell ; 154(4): 748-62, 2013 Aug 15.

Article in English | MEDLINE | ID: mdl-23910378

3.

Characterization of tRNA splicing enzymes RNA ligase and tRNA 2'-phosphotransferase from the pathogenic fungi Mucorales.

Ghosh, Shreya; Dantuluri, Swathi; Jacewicz, Agata; Sanchez, Ana M; Abdullahu, Leonora; Damha, Masad J; Schwer, Beate; Shuman, Stewart.

RNA ; 30(4): 367-380, 2024 Mar 18.

Article in English | MEDLINE | ID: mdl-38238085

4.

Structural basis for Tpt1-catalyzed 2'-PO₄ transfer from RNA and NADP(H) to NAD.

Jacewicz, Agata; Dantuluri, Swathi; Shuman, Stewart.

Proc Natl Acad Sci U S A ; 120(44): e2312999120, 2023 Oct 31.

Article in English | MEDLINE | ID: mdl-37883434

5.

Factors governing the transcriptome changes and chronological lifespan of fission yeast during phosphate starvation.

Garg, Angad; Sanchez, Ana M; Schwer, Beate; Shuman, Stewart.

J Biol Chem ; 300(3): 105718, 2024 Mar.

Article in English | MEDLINE | ID: mdl-38311173

6.

Fission yeast poly(A) polymerase active site mutation Y86D alleviates the rad24Δ asp1-H397A synthetic growth defect and up-regulates mRNAs targeted by MTREC and Mmi1.

Garg, Angad; Schwer, Beate; Shuman, Stewart.

RNA ; 29(11): 1738-1753, 2023 11.

Article in English | MEDLINE | ID: mdl-37586723

7.

Duf89 abets lncRNA control of fission yeast phosphate homeostasis via its antagonism of precocious lncRNA transcription termination.

Sanchez, Ana M; Garg, Angad; Schwer, Beate; Shuman, Stewart.

RNA ; 29(6): 808-825, 2023 06.

Article in English | MEDLINE | ID: mdl-36882296

8.

Cellular strategies for regulating DNA supercoiling: a single-molecule perspective.

Koster, Daniel A; Crut, Aurélien; Shuman, Stewart; Bjornsti, Mary-Ann; Dekker, Nynke H.

Cell ; 142(4): 519-30, 2010 Aug 20.

Article in English | MEDLINE | ID: mdl-20723754

9.

Mycobacterial helicase Lhr abets resistance to DNA crosslinking agents mitomycin C and cisplatin.

Warren, Garrett M; Ejaz, Anam; Fay, Allison; Glickman, Michael S; Shuman, Stewart.

Nucleic Acids Res ; 51(1): 218-235, 2023 01 11.

Article in English | MEDLINE | ID: mdl-36610794

10.

Cellular responses to long-term phosphate starvation of fission yeast: Maf1 determines fate choice between quiescence and death associated with aberrant tRNA biogenesis.

Garg, Angad; Sanchez, Ana M; Miele, Matthew; Schwer, Beate; Shuman, Stewart.

Nucleic Acids Res ; 51(7): 3094-3115, 2023 04 24.

Article in English | MEDLINE | ID: mdl-36794724

11.

Structures of RNA ligase RtcB in complexes with divalent cations and GTP.

Jacewicz, Agata; Dantuluri, Swathi; Shuman, Stewart.

RNA ; 28(11): 1509-1518, 2022 11.

Article in English | MEDLINE | ID: mdl-36130078

12.

Genetic screen for suppression of transcriptional interference reveals fission yeast 14-3-3 protein Rad24 as an antagonist of precocious Pol2 transcription termination.

Garg, Angad; Shuman, Stewart; Schwer, Beate.

Nucleic Acids Res ; 50(2): 803-819, 2022 01 25.

Article in English | MEDLINE | ID: mdl-34967420

13.

Structure-activity relationships at a nucleobase-stacking tryptophan required for chemomechanical coupling in the DNA resecting motor-nuclease AdnAB.

Warren, Garrett M; Meir, Aviv; Wang, Juncheng; Patel, Dinshaw J; Greene, Eric C; Shuman, Stewart.

Nucleic Acids Res ; 50(2): 952-961, 2022 01 25.

Article in English | MEDLINE | ID: mdl-34967418

14.

Genetic screen for suppression of transcriptional interference identifies a gain-of-function mutation in Pol2 termination factor Seb1.

Schwer, Beate; Garg, Angad; Jacewicz, Agata; Shuman, Stewart.

Proc Natl Acad Sci U S A ; 118(33)2021 08 17.

Article in English | MEDLINE | ID: mdl-34389684

15.

Structure-function analysis of fission yeast cleavage and polyadenylation factor (CPF) subunit Ppn1 and its interactions with Dis2 and Swd22.

Benjamin, Bradley; Sanchez, Ana M; Garg, Angad; Schwer, Beate; Shuman, Stewart.

PLoS Genet ; 17(3): e1009452, 2021 03.

Article in English | MEDLINE | ID: mdl-33711009

16.

Clutch mechanism of chemomechanical coupling in a DNA resecting motor nuclease.

Unciuleac, Mihaela-Carmen; Meir, Aviv; Xue, Chaoyou; Warren, Garrett M; Greene, Eric C; Shuman, Stewart.

Proc Natl Acad Sci U S A ; 118(11)2021 03 16.

Article in English | MEDLINE | ID: mdl-33836607

17.

Fission yeast Duf89 and Duf8901 are cobalt/nickel-dependent phosphatase-pyrophosphatases that act via a covalent aspartyl-phosphate intermediate.

Sanchez, Ana M; Jacewicz, Agata; Shuman, Stewart.

J Biol Chem ; 298(5): 101851, 2022 05.

Article in English | MEDLINE | ID: mdl-35314193

18.

Structure of 3'-PO₄/5'-OH RNA ligase RtcB in complex with a 5'-OH oligonucleotide.

Banerjee, Ankan; Goldgur, Yehuda; Shuman, Stewart.

RNA ; 2021 Feb 22.

Article in English | MEDLINE | ID: mdl-33619169

19.

Activity and substrate specificity of Candida, Aspergillus, and Coccidioides Tpt1: essential tRNA splicing enzymes and potential anti-fungal targets.

Dantuluri, Swathi; Schwer, Beate; Abdullahu, Leonora; Damha, Masad J; Shuman, Stewart.

RNA ; 2021 Jan 28.

Article in English | MEDLINE | ID: mdl-33509912

20.

Transcriptional profiling of fission yeast RNA polymerase II CTD mutants.