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1.
Neuronal Ndst1 depletion accelerates prion protein clearance and slows neurodegeneration in prion infection.
PLoS Pathog
; 19(9): e1011487, 2023 09.
Article
in English
| MEDLINE | ID: mdl-37747931
2.
Diminished Neuronal ESCRT-0 Function Exacerbates AMPA Receptor Derangement and Accelerates Prion-Induced Neurodegeneration.
J Neurosci
; 43(21): 3970-3984, 2023 05 24.
Article
in English
| MEDLINE | ID: mdl-37019623
3.
A Soluble PrPC Derivative and Membrane-Anchored PrPC in Extracellular Vesicles Attenuate Innate Immunity by Engaging the NMDA-R/LRP1 Receptor Complex.
J Immunol
; 208(1): 85-96, 2022 01 01.
Article
in English
| MEDLINE | ID: mdl-34810220
4.
Cellular prion protein in human plasma-derived extracellular vesicles promotes neurite outgrowth via the NMDA receptor-LRP1 receptor system.
J Biol Chem
; 298(3): 101642, 2022 03.
Article
in English
| MEDLINE | ID: mdl-35090893
5.
Distinct conformers of amyloid beta accumulate in the neocortex of patients with rapidly progressive Alzheimer's disease.
J Biol Chem
; 297(5): 101267, 2021 11.
Article
in English
| MEDLINE | ID: mdl-34599965
6.
Prions induce an early Arc response and a subsequent reduction in mGluR5 in the hippocampus.
Neurobiol Dis
; 172: 105834, 2022 10 01.
Article
in English
| MEDLINE | ID: mdl-35905927
7.
Minimal change prion retinopathy: Morphometric comparison of retinal and brain prion deposits in Creutzfeldt-Jakob disease.
Exp Eye Res
; 222: 109172, 2022 09.
Article
in English
| MEDLINE | ID: mdl-35803332
8.
A soluble derivative of PrPC activates cell-signaling and regulates cell physiology through LRP1 and the NMDA receptor.
J Biol Chem
; 295(41): 14178-14188, 2020 10 09.
Article
in English
| MEDLINE | ID: mdl-32788217
9.
Prion protein post-translational modifications modulate heparan sulfate binding and limit aggregate size in prion disease.
Neurobiol Dis
; 142: 104955, 2020 08.
Article
in English
| MEDLINE | ID: mdl-32454127
10.
Shortening heparan sulfate chains prolongs survival and reduces parenchymal plaques in prion disease caused by mobile, ADAM10-cleaved prions.
Acta Neuropathol
; 139(3): 527-546, 2020 03.
Article
in English
| MEDLINE | ID: mdl-31673874
11.
Seeding selectivity and ultrasensitive detection of tau aggregate conformers of Alzheimer disease.
Acta Neuropathol
; 137(4): 585-598, 2019 04.
Article
in English
| MEDLINE | ID: mdl-30570675
12.
Asparagine and glutamine ladders promote cross-species prion conversion.
J Biol Chem
; 292(46): 19076-19086, 2017 11 17.
Article
in English
| MEDLINE | ID: mdl-28931606
13.
Short and sweet: How glycans impact prion conversion, cofactor interactions, and cross-species transmission.
PLoS Pathog
; 17(1): e1009123, 2021 01.
Article
in English
| MEDLINE | ID: mdl-33444414
14.
Lymphotoxin-dependent prion replication in inflammatory stromal cells of granulomas.
Immunity
; 29(6): 998-1008, 2008 Dec 19.
Article
in English
| MEDLINE | ID: mdl-19100703
15.
Multiple Mechanisms of Unfolded Protein Response-Induced Cell Death.
Am J Pathol
; 185(7): 1800-8, 2015 Jul.
Article
in English
| MEDLINE | ID: mdl-25956028
16.
Protein profiling of isolated uterine AA amyloidosis causing fetal death in goats.
FASEB J
; 29(3): 911-9, 2015 Mar.
Article
in English
| MEDLINE | ID: mdl-25422367
17.
Polymorphism of Amyloid Fibrils In Vivo.
Angew Chem Int Ed Engl
; 55(15): 4822-5, 2016 Apr 04.
Article
in English
| MEDLINE | ID: mdl-26954430
18.
Prion transmission prevented by modifying the ß2-α2 loop structure of host PrPC.
J Neurosci
; 34(3): 1022-7, 2014 Jan 15.
Article
in English
| MEDLINE | ID: mdl-24431459
19.
A proposed mechanism for the promotion of prion conversion involving a strictly conserved tyrosine residue in the ß2-α2 loop of PrPC.
J Biol Chem
; 289(15): 10660-10667, 2014 Apr 11.
Article
in English
| MEDLINE | ID: mdl-24596090
20.
De novo prion aggregates trigger autophagy in skeletal muscle.
J Virol
; 88(4): 2071-82, 2014 Feb.
Article
in English
| MEDLINE | ID: mdl-24307586