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J Am Chem Soc ; 136(50): 17394-7, 2014 Dec 17.
Article in English | MEDLINE | ID: mdl-25487127

ABSTRACT

Gold-silver core-shell nanoparticles stabilized with a common sweetener, aspartame (AuNP@Ag@Asm), combine the antimicrobial properties of silver with the photoinduced plasmon-mediated photothermal effects of gold. The particles were tested with several bacterial strains, while biocompatibility was verified with human dermal fibroblasts.


Subject(s)
Anti-Bacterial Agents/pharmacology , Aspartame/chemistry , Gold/chemistry , Metal Nanoparticles/chemistry , Silver/chemistry , Staphylococcus aureus/drug effects , Anti-Bacterial Agents/chemistry , Aspartame/pharmacology , Drug Stability , Fibroblasts/drug effects , Humans , Microbial Sensitivity Tests , Microscopy, Electron, Transmission , Molecular Structure , Time Factors
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