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1.
Two-dimensional IR spectroscopy of the anti-HIV agent KP1212 reveals protonated and neutral tautomers that influence pH-dependent mutagenicity.
Proc Natl Acad Sci U S A
; 112(11): 3229-34, 2015 Mar 17.
Article
in English
| MEDLINE | ID: mdl-25733867
2.
Intrinsic mutagenic properties of 5-chlorocytosine: A mechanistic connection between chronic inflammation and cancer.
Proc Natl Acad Sci U S A
; 112(33): E4571-80, 2015 Aug 18.
Article
in English
| MEDLINE | ID: mdl-26243878
3.
Role of tautomerism in RNA biochemistry.
RNA
; 21(1): 1-13, 2015 Jan.
Article
in English
| MEDLINE | ID: mdl-25516996
4.
Oncometabolites d- and l-2-Hydroxyglutarate Inhibit the AlkB Family DNA Repair Enzymes under Physiological Conditions.
Chem Res Toxicol
; 30(4): 1102-1110, 2017 04 17.
Article
in English
| MEDLINE | ID: mdl-28269980
5.
A two-step chemical mechanism for ribosome-catalysed peptide bond formation.
Nature
; 476(7359): 236-9, 2011 Jul 17.
Article
in English
| MEDLINE | ID: mdl-21765427
6.
Next-generation sequencing reveals the biological significance of the N(2),3-ethenoguanine lesion in vivo.
Nucleic Acids Res
; 43(11): 5489-500, 2015 Jun 23.
Article
in English
| MEDLINE | ID: mdl-25837992
7.
Tautomerism provides a molecular explanation for the mutagenic properties of the anti-HIV nucleoside 5-aza-5,6-dihydro-2'-deoxycytidine.
Proc Natl Acad Sci U S A
; 111(32): E3252-9, 2014 Aug 12.
Article
in English
| MEDLINE | ID: mdl-25071207
8.
The AlkB Family of Fe(II)/α-Ketoglutarate-dependent Dioxygenases: Repairing Nucleic Acid Alkylation Damage and Beyond.
J Biol Chem
; 290(34): 20734-20742, 2015 Aug 21.
Article
in English
| MEDLINE | ID: mdl-26152727
9.
Mechanism of repair of acrolein- and malondialdehyde-derived exocyclic guanine adducts by the α-ketoglutarate/Fe(II) dioxygenase AlkB.
Chem Res Toxicol
; 27(9): 1619-31, 2014 Sep 15.
Article
in English
| MEDLINE | ID: mdl-25157679
10.
Structural Insights Into Tautomeric Dynamics in Nucleic Acids and in Antiviral Nucleoside Analogs.
Front Mol Biosci
; 8: 823253, 2021.
Article
in English
| MEDLINE | ID: mdl-35145998
11.
Transition states of uncatalyzed hydrolysis and aminolysis reactions of a ribosomal P-site substrate determined by kinetic isotope effects.
Biochemistry
; 49(18): 3868-78, 2010 May 11.
Article
in English
| MEDLINE | ID: mdl-20359191
12.
Second generation transition state analogue inhibitors of human 5'-methylthioadenosine phosphorylase.
J Med Chem
; 48(14): 4679-89, 2005 Jul 14.
Article
in English
| MEDLINE | ID: mdl-16000004
13.
Lewis Acid Catalyzed Annulation of Nitrones with Oxiranes, Aziridines, and Thiiranes.
Org Lett
; 17(18): 4506-9, 2015 Sep 18.
Article
in English
| MEDLINE | ID: mdl-26332095
14.
Targeting the polyamine pathway with transition-state analogue inhibitors of 5'-methylthioadenosine phosphorylase.
J Med Chem
; 47(12): 3275-81, 2004 Jun 03.
Article
in English
| MEDLINE | ID: mdl-15163207
15.
Direct observation of multiple tautomers of oxythiamine and their recognition by the thiamine pyrophosphate riboswitch.
ACS Chem Biol
; 9(1): 227-36, 2014 Jan 17.
Article
in English
| MEDLINE | ID: mdl-24252063
16.
Synthesis of 1,3,5-trisubstituted pyrazolines via Zn(II)-catalyzed double hydroamination of enynes with aryl hydrazines.
Chem Commun (Camb)
; 47(39): 11116-8, 2011 Oct 21.
Article
in English
| MEDLINE | ID: mdl-21909551
17.
Transition-state analysis of S. pneumoniae 5'-methylthioadenosine nucleosidase.
J Am Chem Soc
; 129(10): 2783-95, 2007 Mar 14.
Article
in English
| MEDLINE | ID: mdl-17298059
18.
Transition-state variation in human, bovine, and Plasmodium falciparum adenosine deaminases.
J Am Chem Soc
; 129(25): 8008-17, 2007 Jun 27.
Article
in English
| MEDLINE | ID: mdl-17536804
19.
Picomolar inhibitors as transition-state probes of 5'-methylthioadenosine nucleosidases.
ACS Chem Biol
; 2(11): 725-34, 2007 Nov 20.
Article
in English
| MEDLINE | ID: mdl-18030989
20.
Transition-state structure of human 5'-methylthioadenosine phosphorylase.
J Am Chem Soc
; 128(45): 14691-6, 2006 Nov 15.
Article
in English
| MEDLINE | ID: mdl-17090056