ABSTRACT
Polycystic ovary syndrome (PCOS) is a common endocrinopathy that has been associated with impaired fertility. This chapter reviews the underlying pathophysiology of PCOS and the associated fertility barriers of the condition. Psychologic concerns, hypothalamic-pituitary, ovarian, and mitochondria dysfunction, obesity, and the role of vitamin D in PCOS are considered with respect to fertility. Lastly, pregnancy risk factors associated with PCOS are also reviewed.
Subject(s)
Polycystic Ovary Syndrome , Female , Fertility , Humans , Obesity/complications , Polycystic Ovary Syndrome/complications , Pregnancy , Vitamin DABSTRACT
Introduction The number of female patients with CF able to consider pregnancy has increased with improved therapies. This study explored attitudes and decision making regarding pregnancy among young women with CF. Methods Twenty-two women with CF ages 18-30 years completed semi-structured, in-person interviews exploring experiences with preconception counseling and reproductive care in the CF setting. Interviews were audio-recorded, transcribed, and coded using a thematic analysis approach. Results Participants indicated CF is a major factor in pregnancy decision making. Although women acknowledged that CF influences attitudes toward pregnancy, many expressed confusion about how CF can affect fertility/pregnancy. Many perceived disapproval from CF providers regarding pregnancy and were dissatisfied with reproductive care in the CF setting. Discussion Young female patients with CF reported poor understanding of the effect of CF on fertility and pregnancy and limited preconception counseling in CF care. Improvements in female sexual and reproductive health care in CF are warranted.
Subject(s)
Cystic Fibrosis , Health Knowledge, Attitudes, Practice , Pregnancy/psychology , Reproductive Health , Sexual Behavior/psychology , Adolescent , Adult , Decision Making , Female , Humans , Women's Health , Young AdultABSTRACT
INTRODUCTION: Endometriosis is increasingly recognized as a challenging problem of both diagnosis and management in adolescent gynecology. Areas covered: This special report summarizes the current practices in the evaluation and management of endometriosis in adolescent patients. Expert commentary: We recommend prompt recognition and treatment of endometriosis whenever possible. Management should begin with empiric treatment with NSAIDS and hormonal therapy if complaints of pain interfering with daily activities are elicited. If a patient fails medical therapy after three to six months, surgical intervention is warranted by a clinician experienced in operating in this age range and familiar with the appearance of endometriosis in this age range.