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1.

The Lineage-Defining Transcription Factors SOX2 and NKX2-1 Determine Lung Cancer Cell Fate and Shape the Tumor Immune Microenvironment.

Mollaoglu, Gurkan; Jones, Alex; Wait, Sarah J; Mukhopadhyay, Anandaroop; Jeong, Sangmin; Arya, Rahul; Camolotto, Soledad A; Mosbruger, Timothy L; Stubben, Chris J; Conley, Christopher J; Bhutkar, Arjun; Vahrenkamp, Jeffery M; Berrett, Kristofer C; Cessna, Melissa H; Lane, Thomas E; Witt, Benjamin L; Salama, Mohamed E; Gertz, Jason; Jones, Kevin B; Snyder, Eric L; Oliver, Trudy G.

Immunity ; 49(4): 764-779.e9, 2018 10 16.

Article in English | MEDLINE | ID: mdl-30332632

2.

Transcriptional Circuitry of NKX2-1 and SOX1 Defines an Unrecognized Lineage Subtype of Small-Cell Lung Cancer.

Kong, Ranran; Patel, Ayushi S; Sato, Takashi; Jiang, Feng; Yoo, Seungyeul; Bao, Li; Sinha, Abhilasha; Tian, Yang; Fridrikh, Maya; Liu, Shuhui; Feng, Jie; He, Xijing; Jiang, Jiantao; Ma, Yuefeng; Grullon, Karina; Yang, Dawei; Powell, Charles A; Beasley, Mary Beth; Zhu, Jun; Snyder, Eric L; Li, Shaomin; Watanabe, Hideo.

Am J Respir Crit Care Med ; 206(12): 1480-1494, 2022 12 15.

Article in English | MEDLINE | ID: mdl-35848993

3.

Foxa2 and Cdx2 cooperate with Nkx2-1 to inhibit lung adenocarcinoma metastasis.

Li, Carman Man-Chung; Gocheva, Vasilena; Oudin, Madeleine J; Bhutkar, Arjun; Wang, Shi Yun; Date, Saya R; Ng, Sheng Rong; Whittaker, Charles A; Bronson, Roderick T; Snyder, Eric L; Gertler, Frank B; Jacks, Tyler.

Genes Dev ; 29(17): 1850-62, 2015 Sep 01.

Article in English | MEDLINE | ID: mdl-26341558

4.

SnapShot: Lung cancer models.

Farago, Anna F; Snyder, Eric L; Jacks, Tyler.

Cell ; 149(1): 246-246.e1, 2012 Mar 30.

Article in English | MEDLINE | ID: mdl-22464334

5.

Reciprocal regulation of pancreatic ductal adenocarcinoma growth and molecular subtype by HNF4α and SIX1/4.

Camolotto, Soledad A; Belova, Veronika K; Torre-Healy, Luke; Vahrenkamp, Jeffery M; Berrett, Kristofer C; Conway, Hannah; Shea, Jill; Stubben, Chris; Moffitt, Richard; Gertz, Jason; Snyder, Eric L.

Gut ; 70(5): 900-914, 2021 05.

Article in English | MEDLINE | ID: mdl-32826305

6.

Nkx2-1 represses a latent gastric differentiation program in lung adenocarcinoma.

Snyder, Eric L; Watanabe, Hideo; Magendantz, Margaret; Hoersch, Sebastian; Chen, Tiffany A; Wang, Diana G; Crowley, Denise; Whittaker, Charles A; Meyerson, Matthew; Kimura, Shioko; Jacks, Tyler.

Mol Cell ; 50(2): 185-99, 2013 Apr 25.

Article in English | MEDLINE | ID: mdl-23523371

7.

Integrated cistromic and expression analysis of amplified NKX2-1 in lung adenocarcinoma identifies LMO3 as a functional transcriptional target.

Watanabe, Hideo; Francis, Joshua M; Woo, Michele S; Etemad, Banafsheh; Lin, Wenchu; Fries, Daniel F; Peng, Shouyong; Snyder, Eric L; Tata, Purushothama Rao; Izzo, Francesca; Schinzel, Anna C; Cho, Jeonghee; Hammerman, Peter S; Verhaak, Roel G; Hahn, William C; Rajagopal, Jayaraj; Jacks, Tyler; Meyerson, Matthew.

Genes Dev ; 27(2): 197-210, 2013 Jan 15.

Article in English | MEDLINE | ID: mdl-23322301

8.

Nuclear factor I/B is an oncogene in small cell lung cancer.

Dooley, Alison L; Winslow, Monte M; Chiang, Derek Y; Banerji, Shantanu; Stransky, Nicolas; Dayton, Talya L; Snyder, Eric L; Senna, Stephanie; Whittaker, Charles A; Bronson, Roderick T; Crowley, Denise; Barretina, Jordi; Garraway, Levi; Meyerson, Matthew; Jacks, Tyler.

Genes Dev ; 25(14): 1470-5, 2011 Jul 15.

Article in English | MEDLINE | ID: mdl-21764851

9.

Suppression of lung adenocarcinoma progression by Nkx2-1.

Winslow, Monte M; Dayton, Talya L; Verhaak, Roel G W; Kim-Kiselak, Caroline; Snyder, Eric L; Feldser, David M; Hubbard, Diana D; DuPage, Michel J; Whittaker, Charles A; Hoersch, Sebastian; Yoon, Stephanie; Crowley, Denise; Bronson, Roderick T; Chiang, Derek Y; Meyerson, Matthew; Jacks, Tyler.

Nature ; 473(7345): 101-4, 2011 May 05.

Article in English | MEDLINE | ID: mdl-21471965

10.

c-Jun promotes cell migration and drives expression of the motility factor ENPP2 in soft tissue sarcomas.

Sioletic, Stefano; Czaplinski, Jeffrey; Hu, Lan; Fletcher, Jonathan A; Fletcher, Christopher D M; Wagner, Andrew J; Loda, Massimo; Demetri, George D; Sicinska, Ewa T; Snyder, Eric L.

J Pathol ; 234(2): 190-202, 2014 Oct.

Article in English | MEDLINE | ID: mdl-24852265

11.

Aberrant AKT activation drives well-differentiated liposarcoma.

Gutierrez, Alejandro; Snyder, Eric L; Marino-Enriquez, Adrian; Zhang, Yi-Xiang; Sioletic, Stefano; Kozakewich, Elena; Grebliunaite, Ruta; Ou, Wen-Bin; Sicinska, Ewa; Raut, Chandrajit P; Demetri, George D; Perez-Atayde, Antonio R; Wagner, Andrew J; Fletcher, Jonathan A; Fletcher, Christopher D M; Look, A Thomas.

Proc Natl Acad Sci U S A ; 108(39): 16386-91, 2011 Sep 27.

Article in English | MEDLINE | ID: mdl-21930930

12.

Inhibition of ULK1/2 and KRAS ^G12C controls tumor growth in preclinical models of lung cancer.

Ghazi, Phaedra C; O'Toole, Kayla T; Srinivas Boggaram, Sanjana; Scherzer, Michael T; Silvis, Mark R; Zhang, Yun; Bogdan, Madhumita; Smith, Bryan D; Lozano, Guillermina; Flynn, Daniel L; Snyder, Eric L; Kinsey, Conan G; McMahon, Martin.

bioRxiv ; 2024 Feb 08.

Article in English | MEDLINE | ID: mdl-38370808

13.

FoxA1/2-dependent epigenomic reprogramming drives lineage switching in lung adenocarcinoma.

Gillis, Katherine; Orellana, Walter A; Wilson, Emily; Parnell, Timothy J; Fort, Gabriela; Dadzie, Headtlove Essel; Zhang, Xiaoyang; Snyder, Eric L.

bioRxiv ; 2023 Nov 02.

Article in English | MEDLINE | ID: mdl-37961260

14.

NKX2-1 controls lung cancer progression by inducing DUSP6 to dampen ERK activity.

Ingram, Kelley; Samson, Shiela C; Zewdu, Rediet; Zitnay, Rebecca G; Snyder, Eric L; Mendoza, Michelle C.

Oncogene ; 41(2): 293-300, 2022 01.

Article in English | MEDLINE | ID: mdl-34689179

15.

FoxA1 and FoxA2 control growth and cellular identity in NKX2-1-positive lung adenocarcinoma.

Orstad, Grace; Fort, Gabriela; Parnell, Timothy J; Jones, Alex; Stubben, Chris; Lohman, Brian; Gillis, Katherine L; Orellana, Walter; Tariq, Rushmeen; Klingbeil, Olaf; Kaestner, Klaus; Vakoc, Christopher R; Spike, Benjamin T; Snyder, Eric L.

Dev Cell ; 57(15): 1866-1882.e10, 2022 08 08.

Article in English | MEDLINE | ID: mdl-35835117

16.

Cell type-specific DNA methylation patterns in the human breast.

Bloushtain-Qimron, Noga; Yao, Jun; Snyder, Eric L; Shipitsin, Michail; Campbell, Lauren L; Mani, Sendurai A; Hu, Min; Chen, Haiyan; Ustyansky, Vadim; Antosiewicz, Jessica E; Argani, Pedram; Halushka, Marc K; Thomson, James A; Pharoah, Paul; Porgador, Angel; Sukumar, Saraswati; Parsons, Ramon; Richardson, Andrea L; Stampfer, Martha R; Gelman, Rebecca S; Nikolskaya, Tatiana; Nikolsky, Yuri; Polyak, Kornelia.

Proc Natl Acad Sci U S A ; 105(37): 14076-81, 2008 Sep 16.

Article in English | MEDLINE | ID: mdl-18780791

17.

An NKX2-1/ERK/WNT feedback loop modulates gastric identity and response to targeted therapy in lung adenocarcinoma.

Zewdu, Rediet; Mehrabad, Elnaz Mirzaei; Ingram, Kelley; Fang, Pengshu; Gillis, Katherine L; Camolotto, Soledad A; Orstad, Grace; Jones, Alex; Mendoza, Michelle C; Spike, Benjamin T; Snyder, Eric L.

Elife ; 102021 04 06.

Article in English | MEDLINE | ID: mdl-33821796

18.

c-Jun amplification and overexpression are oncogenic in liposarcoma but not always sufficient to inhibit the adipocytic differentiation programme.

Snyder, Eric L; Sandstrom, Deborah J; Law, Kenneth; Fiore, Christopher; Sicinska, Ewa; Brito, Joseph; Bailey, Dyane; Fletcher, Jonathan A; Loda, Massimo; Rodig, Scott J; Dal Cin, Paola; Fletcher, Christopher D M.

J Pathol ; 218(3): 292-300, 2009 Jul.

Article in English | MEDLINE | ID: mdl-19449367

19.

Identification of CD44v6(+)/CD24- breast carcinoma cells in primary human tumors by quantum dot-conjugated antibodies.

Snyder, Eric L; Bailey, Dyane; Shipitsin, Michail; Polyak, Kornelia; Loda, Massimo.

Lab Invest ; 89(8): 857-66, 2009 Aug.

Article in English | MEDLINE | ID: mdl-19488035

20.

Publisher Correction: Protective autophagy elicited by RAFâMEKâERK inhibition suggests a treatment strategy for RAS-driven cancers.

Kinsey, Conan G; Camolotto, Soledad A; Boespflug, Amelie M; Guillen, Katrin P; Foth, Mona; Truong, Amanda; Schuman, Sophia S; Shea, Jill E; Seipp, Michael T; Yap, Jeffrey T; Burrell, Lance D; Lum, David H; Whisenant, Jonathan R; Gilcrease, G Weldon; Cavalieri, Courtney C; Rehbein, Kaitrin M; Cutler, Stephanie L; Affolter, Kajsa E; Welm, Alana L; Welm, Bryan E; Scaife, Courtney L; Snyder, Eric L; McMahon, Martin.

Nat Med ; 25(5): 861, 2019 May.

Article in English | MEDLINE | ID: mdl-30918364

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