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1.

Mural cell-derived chemokines provide a protective niche to safeguard vascular macrophages and limit chronic inflammation.

Pekayvaz, Kami; Gold, Christoph; Hoseinpour, Parandis; Engel, Anouk; Martinez-Navarro, Alejandro; Eivers, Luke; Coletti, Raffaele; Joppich, Markus; Dionísio, Flávio; Kaiser, Rainer; Tomas, Lukas; Janjic, Aleksandar; Knott, Maximilian; Mehari, Fitsumbirhan; Polewka, Vivien; Kirschner, Megan; Boda, Annegret; Nicolai, Leo; Schulz, Heiko; Titova, Anna; Kilani, Badr; Lorenz, Michael; Fingerle-Rowson, Günter; Bucala, Richard; Enard, Wolfgang; Zimmer, Ralf; Weber, Christian; Libby, Peter; Schulz, Christian; Massberg, Steffen; Stark, Konstantin.

Immunity ; 56(10): 2325-2341.e15, 2023 Oct 10.

Article in English | MEDLINE | ID: mdl-37652021

2.

Migrating Platelets Are Mechano-scavengers that Collect and Bundle Bacteria.

Gaertner, Florian; Ahmad, Zerkah; Rosenberger, Gerhild; Fan, Shuxia; Nicolai, Leo; Busch, Benjamin; Yavuz, Gökce; Luckner, Manja; Ishikawa-Ankerhold, Hellen; Hennel, Roman; Benechet, Alexandre; Lorenz, Michael; Chandraratne, Sue; Schubert, Irene; Helmer, Sebastian; Striednig, Bianca; Stark, Konstantin; Janko, Marek; Böttcher, Ralph T; Verschoor, Admar; Leon, Catherine; Gachet, Christian; Gudermann, Thomas; Mederos Y Schnitzler, Michael; Pincus, Zachary; Iannacone, Matteo; Haas, Rainer; Wanner, Gerhard; Lauber, Kirsten; Sixt, Michael; Massberg, Steffen.

Cell ; 171(6): 1368-1382.e23, 2017 Nov 30.

Article in English | MEDLINE | ID: mdl-29195076

3.

Neutrophil "plucking" on megakaryocytes drives platelet production and boosts cardiovascular disease.

Petzold, Tobias; Zhang, Zhe; Ballesteros, Iván; Saleh, Inas; Polzin, Amin; Thienel, Manuela; Liu, Lulu; Ul Ain, Qurrat; Ehreiser, Vincent; Weber, Christian; Kilani, Badr; Mertsch, Pontus; Götschke, Jeremias; Cremer, Sophie; Fu, Wenwen; Lorenz, Michael; Ishikawa-Ankerhold, Hellen; Raatz, Elisabeth; El-Nemr, Shaza; Görlach, Agnes; Marhuenda, Esther; Stark, Konstantin; Pircher, Joachim; Stegner, David; Gieger, Christian; Schmidt-Supprian, Marc; Gaertner, Florian; Almendros, Isaac; Kelm, Malte; Schulz, Christian; Hidalgo, Andrés; Massberg, Steffen.

Immunity ; 55(12): 2285-2299.e7, 2022 12 13.

Article in English | MEDLINE | ID: mdl-36272416

4.

Capillary and arteriolar pericytes attract innate leukocytes exiting through venules and 'instruct' them with pattern-recognition and motility programs.

Stark, Konstantin; Eckart, Annekathrin; Haidari, Selgai; Tirniceriu, Anca; Lorenz, Michael; von Brühl, Marie-Luise; Gärtner, Florian; Khandoga, Alexander Georg; Legate, Kyle R; Pless, Robert; Hepper, Ingrid; Lauber, Kirsten; Walzog, Barbara; Massberg, Steffen.

Nat Immunol ; 14(1): 41-51, 2013 Jan.

Article in English | MEDLINE | ID: mdl-23179077

5.

Targeting platelet-derived CXCL12 impedes arterial thrombosis.

Leberzammer, Julian; Agten, Stijn M; Blanchet, Xavier; Duan, Rundan; Ippel, Hans; Megens, Remco T A; Schulz, Christian; Aslani, Maria; Duchene, Johan; Döring, Yvonne; Jooss, Natalie J; Zhang, Pengyu; Brandl, Richard; Stark, Konstantin; Siess, Wolfgang; Jurk, Kerstin; Heemskerk, Johan W M; Hackeng, Tilman M; Mayo, Kevin H; Weber, Christian; von Hundelshausen, Philipp.

Blood ; 139(17): 2691-2705, 2022 04 28.

Article in English | MEDLINE | ID: mdl-35313337

6.

Procoagulant platelet sentinels prevent inflammatory bleeding through GPIIBIIIA and GPVI.

Kaiser, Rainer; Escaig, Raphael; Kranich, Jan; Hoffknecht, Marie-Louise; Anjum, Afra; Polewka, Vivien; Mader, Magdalena; Hu, Wenbo; Belz, Larissa; Gold, Christoph; Titova, Anna; Lorenz, Michael; Pekayvaz, Kami; Kääb, Stefan; Gaertner, Florian; Stark, Konstantin; Brocker, Thomas; Massberg, Steffen; Nicolai, Leo.

Blood ; 140(2): 121-139, 2022 07 14.

Article in English | MEDLINE | ID: mdl-35472164

7.

Thrombocytopenia and splenic platelet-directed immune responses after IV ChAdOx1 nCov-19 administration.

Nicolai, Leo; Leunig, Alexander; Pekayvaz, Kami; Esefeld, Max; Anjum, Afra; Rath, Justina; Riedlinger, Eva; Ehreiser, Vincent; Mader, Magdalena; Eivers, Luke; Hoffknecht, Marie-Louise; Zhang, Zhe; Kugelmann, Daniela; Rossaro, Dario; Escaig, Raphael; Kaiser, Rainer; Polewka, Vivien; Titova, Anna; Petzold, Tobias; Spiekermann, Karsten; Iannacone, Matteo; Thiele, Thomas; Greinacher, Andreas; Stark, Konstantin; Massberg, Steffen.

Blood ; 140(5): 478-490, 2022 08 04.

Article in English | MEDLINE | ID: mdl-35486845

8.

Impaired function and delayed regeneration of dendritic cells in COVID-19.

Winheim, Elena; Rinke, Linus; Lutz, Konstantin; Reischer, Anna; Leutbecher, Alexandra; Wolfram, Lina; Rausch, Lisa; Kranich, Jan; Wratil, Paul R; Huber, Johanna E; Baumjohann, Dirk; Rothenfusser, Simon; Schubert, Benjamin; Hilgendorff, Anne; Hellmuth, Johannes C; Scherer, Clemens; Muenchhoff, Maximilian; von Bergwelt-Baildon, Michael; Stark, Konstantin; Straub, Tobias; Brocker, Thomas; Keppler, Oliver T; Subklewe, Marion; Krug, Anne B.

PLoS Pathog ; 17(10): e1009742, 2021 10.

Article in English | MEDLINE | ID: mdl-34614036

9.

Manual Compression versus Suture-Mediated Closure Device Technique for VA-ECMO Decannulation.

Scherer, Clemens; Stremmel, Christopher; Lüsebrink, Enzo; Stocker, Thomas J; Stark, Konstantin; Schönegger, Carmen; Kellnar, Antonia; Kleeberger, Jan; Hanuna, Maja; Petzold, Tobias; Peterss, Sven; Braun, Daniel; Hausleiter, Jörg; Hagl, Christian; Massberg, Steffen; Orban, Martin.

J Interv Cardiol ; 2022: 9915247, 2022.

Article in English | MEDLINE | ID: mdl-35360094

10.

ADP-induced platelet reactivity and bleeding events in patients with acute myocardial infarction complicated by cardiogenic shock.

Scherer, Clemens; Lüsebrink, Enzo; Kupka, Danny; Stocker, Thomas J; Stark, Konstantin; Kleeberger, Jan; Orban, Mathias; Kellnar, Antonia; Petzold, Tobias; Deseive, Simon; Krieg, Kathrin; Würbel, Sara; Kika, Sara; Istrefi, Mario; Brunner, Stefan; Braun, Daniel; Hagl, Christian; Hausleiter, Jörg; Massberg, Steffen; Sibbing, Dirk; Orban, Martin.

Platelets ; 33(3): 371-380, 2022 Apr 03.

Article in English | MEDLINE | ID: mdl-33941008

11.

Immunothrombotic Dysregulation in COVID-19 Pneumonia Is Associated With Respiratory Failure and Coagulopathy.

Nicolai, Leo; Leunig, Alexander; Brambs, Sophia; Kaiser, Rainer; Weinberger, Tobias; Weigand, Michael; Muenchhoff, Maximilian; Hellmuth, Johannes C; Ledderose, Stephan; Schulz, Heiko; Scherer, Clemens; Rudelius, Martina; Zoller, Michael; Höchter, Dominik; Keppler, Oliver; Teupser, Daniel; Zwißler, Bernhard; von Bergwelt-Baildon, Michael; Kääb, Stefan; Massberg, Steffen; Pekayvaz, Kami; Stark, Konstantin.

Circulation ; 142(12): 1176-1189, 2020 09 22.

Article in English | MEDLINE | ID: mdl-32755393

12.

LNKing eosinophilia and atherothrombosis.

Kaiser, Rainer; Stark, Konstantin.

Blood ; 143(17): 1684-1686, 2024 Apr 25.

Article in English | MEDLINE | ID: mdl-38662388

13.

Eosinophil-platelet interactions promote atherosclerosis and stabilize thrombosis with eosinophil extracellular traps.

Marx, Charlotte; Novotny, Julia; Salbeck, Danby; Zellner, Katie R; Nicolai, Leo; Pekayvaz, Kami; Kilani, Badr; Stockhausen, Sven; Bürgener, Niklas; Kupka, Danny; Stocker, Thomas J; Weckbach, Ludwig T; Pircher, Joachim; Moser, Markus; Joner, Michael; Desmet, Walter; Adriaenssens, Tom; Neumann, Franz-Josef; Gerschlick, Anthony H; Ten Berg, Jurrien M; Lorenz, Michael; Stark, Konstantin.

Blood ; 134(21): 1859-1872, 2019 11 21.

Article in English | MEDLINE | ID: mdl-31481482

14.

CD36-triggered cell invasion and persistent tissue colonization by tumor microvesicles during metastasis.

Pfeiler, Susanne; Thakur, Manovriti; Grünauer, Petra; Megens, Remco T A; Joshi, Urjita; Coletti, Raffaele; Samara, Verena; Müller-Stoy, Geraldine; Ishikawa-Ankerhold, Hellen; Stark, Konstantin; Klingl, Andreas; Fröhlich, Thomas; Arnold, Georg J; Wörmann, Sonja; Bruns, Christiane J; Algül, Hana; Weber, Christian; Massberg, Steffen; Engelmann, Bernd.

FASEB J ; 33(2): 1860-1872, 2019 02.

Article in English | MEDLINE | ID: mdl-30207797

15.

A Fundamental Role of Myh9 for Neutrophil Migration in Innate Immunity.

Zehrer, Annette; Pick, Robert; Salvermoser, Melanie; Boda, Annegret; Miller, Meike; Stark, Konstantin; Weckbach, Ludwig T; Walzog, Barbara; Begandt, Daniela.

J Immunol ; 201(6): 1748-1764, 2018 09 15.

Article in English | MEDLINE | ID: mdl-30068598

16.

Autophagy is required for endothelial cell alignment and atheroprotection under physiological blood flow.

Vion, Anne-Clemence; Kheloufi, Marouane; Hammoutene, Adel; Poisson, Johanne; Lasselin, Juliette; Devue, Cecile; Pic, Isabelle; Dupont, Nicolas; Busse, Johanna; Stark, Konstantin; Lafaurie-Janvore, Julie; Barakat, Abdul I; Loyer, Xavier; Souyri, Michele; Viollet, Benoit; Julia, Pierre; Tedgui, Alain; Codogno, Patrice; Boulanger, Chantal M; Rautou, Pierre-Emmanuel.

Proc Natl Acad Sci U S A ; 114(41): E8675-E8684, 2017 10 10.

Article in English | MEDLINE | ID: mdl-28973855

17.

Distinct Pathogenesis of Pancreatic Cancer Microvesicle-Associated Venous Thrombosis Identifies New Antithrombotic Targets In Vivo.

Stark, Konstantin; Schubert, Irene; Joshi, Urjita; Kilani, Badr; Hoseinpour, Parandis; Thakur, Manovriti; Grünauer, Petra; Pfeiler, Susanne; Schmidergall, Tobias; Stockhausen, Sven; Bäumer, Markus; Chandraratne, Sue; von Brühl, Marie-Luise; Lorenz, Michael; Coletti, Raffaele; Reese, Sven; Laitinen, Iina; Wörmann, Sonja Maria; Algül, Hana; Bruns, Christiane J; Ware, Jerry; Mackman, Nigel; Engelmann, Bernd; Massberg, Steffen.

Arterioscler Thromb Vasc Biol ; 38(4): 772-786, 2018 04.

Article in English | MEDLINE | ID: mdl-29419408

18.

Disulfide HMGB1 derived from platelets coordinates venous thrombosis in mice.

Stark, Konstantin; Philippi, Vanessa; Stockhausen, Sven; Busse, Johanna; Antonelli, Antonella; Miller, Meike; Schubert, Irene; Hoseinpour, Parandis; Chandraratne, Sue; von Brühl, Marie-Luise; Gaertner, Florian; Lorenz, Michael; Agresti, Alessandra; Coletti, Raffaele; Antoine, Daniel J; Heermann, Ralf; Jung, Kirsten; Reese, Sven; Laitinen, Iina; Schwaiger, Markus; Walch, Axel; Sperandio, Markus; Nawroth, Peter P; Reinhardt, Christoph; Jäckel, Sven; Bianchi, Marco E; Massberg, Steffen.

Blood ; 128(20): 2435-2449, 2016 11 17.

Article in English | MEDLINE | ID: mdl-27574188

19.

Propagation of thrombosis by neutrophils and extracellular nucleosome networks.

Pfeiler, Susanne; Stark, Konstantin; Massberg, Steffen; Engelmann, Bernd.

Haematologica ; 102(2): 206-213, 2017 02.

Article in English | MEDLINE | ID: mdl-27927771

20.

Critical role of platelet glycoprotein ibα in arterial remodeling.

Chandraratne, Sue; von Bruehl, Marie-Luise; Pagel, Judith-Irina; Stark, Konstantin; Kleinert, Eike; Konrad, Ildiko; Farschtschi, Said; Coletti, Raffaele; Gärtner, Florian; Chillo, Omari; Legate, Kyle R; Lorenz, Michael; Rutkowski, Simon; Caballero-Martinez, Amelia; Starke, Richard; Tirniceriu, Anca; Pauleikhoff, Laurenz; Fischer, Silvia; Assmann, Gerald; Mueller-Hoecker, Josef; Ware, Jerry; Nieswandt, Bernhard; Schaper, Wolfgang; Schulz, Christian; Deindl, Elisabeth; Massberg, Steffen.

Arterioscler Thromb Vasc Biol ; 35(3): 589-97, 2015 Mar.

Article in English | MEDLINE | ID: mdl-25550202

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