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1.
Design and synthesis of novel selective anaplastic lymphoma kinase inhibitors.
Bioorg Med Chem Lett
; 26(3): 1090-1096, 2016 Feb 01.
Article
in English
| MEDLINE | ID: mdl-26750252
2.
Targeting Wnt-driven cancer through the inhibition of Porcupine by LGK974.
Proc Natl Acad Sci U S A
; 110(50): 20224-9, 2013 Dec 10.
Article
in English
| MEDLINE | ID: mdl-24277854
3.
Discovery of Pyridinyl Acetamide Derivatives as Potent, Selective, and Orally Bioavailable Porcupine Inhibitors.
ACS Med Chem Lett
; 7(7): 676-80, 2016 Jul 14.
Article
in English
| MEDLINE | ID: mdl-27437076
4.
(R)-2-Phenylpyrrolidine Substituted Imidazopyridazines: A New Class of Potent and Selective Pan-TRK Inhibitors.
ACS Med Chem Lett
; 6(5): 562-7, 2015 May 14.
Article
in English
| MEDLINE | ID: mdl-26005534
5.
Synthesis, structure-activity relationships, and in vivo efficacy of the novel potent and selective anaplastic lymphoma kinase (ALK) inhibitor 5-chloro-N2-(2-isopropoxy-5-methyl-4-(piperidin-4-yl)phenyl)-N4-(2-(isopropylsulfonyl)phenyl)pyrimidine-2,4-diamine (LDK378) currently in phase 1 and phase 2 clinical trials.
J Med Chem
; 56(14): 5675-90, 2013 Jul 25.
Article
in English
| MEDLINE | ID: mdl-23742252
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