Search details
1.
A phase 1 study to assess the safety, tolerability, and pharmacokinetics of CXD101 in patients with advanced cancer.
Cancer
; 125(1): 99-108, 2019 01 01.
Article
in English
| MEDLINE | ID: mdl-30332497
2.
A first-in-human phase I study to determine the maximum tolerated dose of the oral Src/ABL inhibitor AZD0424.
Br J Cancer
; 118(6): 770-776, 2018 03 20.
Article
in English
| MEDLINE | ID: mdl-29438361
3.
Break-induced ATR and Ddb1-Cul4(Cdt)² ubiquitin ligase-dependent nucleotide synthesis promotes homologous recombination repair in fission yeast.
Genes Dev
; 24(23): 2705-16, 2010 Dec 01.
Article
in English
| MEDLINE | ID: mdl-21123655
4.
Oxidative calcium release from catechol.
Bioorg Med Chem Lett
; 25(7): 1453-4, 2015 Apr 01.
Article
in English
| MEDLINE | ID: mdl-25740160
5.
Mechanistic studies of the inactivation of tyrosinase by resorcinol.
Bioorg Med Chem
; 21(5): 1166-73, 2013 Mar 01.
Article
in English
| MEDLINE | ID: mdl-23352755
6.
The influence of hydroquinone on tyrosinase kinetics.
Bioorg Med Chem
; 20(14): 4364-70, 2012 Jul 15.
Article
in English
| MEDLINE | ID: mdl-22698780
7.
Rapid halogen substitution and dibenzodioxin formation during tyrosinase-catalyzed oxidation of 4-halocatechols.
Chem Res Toxicol
; 24(3): 350-6, 2011 Mar 21.
Article
in English
| MEDLINE | ID: mdl-21306115
8.
The influence of catechol structure on the suicide-inactivation of tyrosinase.
Org Biomol Chem
; 7(17): 3388-90, 2009 Sep 07.
Article
in English
| MEDLINE | ID: mdl-19675891
9.
Enhanced fluorescence detection of cis-combretastatins by post-column photolysis.
J Chromatogr A
; 1181(1-2): 162-5, 2008 Feb 15.
Article
in English
| MEDLINE | ID: mdl-18199444
10.
Evidence consistent with the requirement of cresolase activity for suicide inactivation of tyrosinase.
Tohoku J Exp Med
; 216(3): 231-8, 2008 Nov.
Article
in English
| MEDLINE | ID: mdl-18987457
11.
Radiosensitization In Vivo by Histone Deacetylase Inhibition with No Increase in Early Normal Tissue Radiation Toxicity.
Mol Cancer Ther
; 17(2): 381-392, 2018 02.
Article
in English
| MEDLINE | ID: mdl-28839000
12.
Synthesis and biological properties of bioreductively targeted nitrothienyl prodrugs of combretastatin A-4.
Mol Cancer Ther
; 5(11): 2886-94, 2006 Nov.
Article
in English
| MEDLINE | ID: mdl-17121936
13.
ZD6126: a novel vascular-targeting agent that causes selective destruction of tumor vasculature.
Cancer Res
; 62(24): 7247-53, 2002 Dec 15.
Article
in English
| MEDLINE | ID: mdl-12499266
14.
The radiosensitizing effects of Nelfinavir on pancreatic cancer with and without pancreatic stellate cells.
Radiother Oncol
; 119(2): 300-5, 2016 05.
Article
in English
| MEDLINE | ID: mdl-27247056
15.
Design, synthesis and evaluation of molecularly targeted hypoxia-activated prodrugs.
Nat Protoc
; 11(4): 781-94, 2016 Apr.
Article
in English
| MEDLINE | ID: mdl-27010756
16.
Dual-action combination therapy enhances angiogenesis while reducing tumor growth and spread.
Cancer Cell
; 27(1): 123-37, 2015 Jan 12.
Article
in English
| MEDLINE | ID: mdl-25584895
17.
Oxidation of tetrahydrobiopterin by biological radicals and scavenging of the trihydrobiopterin radical by ascorbate.
Free Radic Biol Med
; 32(3): 203-11, 2002 Feb 01.
Article
in English
| MEDLINE | ID: mdl-11827745
18.
Pharmacology and toxicity of nicotinamide combined with domperidone during fractionated radiotherapy.
Radiother Oncol
; 63(3): 285-91, 2002 Jun.
Article
in English
| MEDLINE | ID: mdl-12142092
19.
5-Fluoroindole-3-acetic acid: a prodrug activated by a peroxidase with potential for use in targeted cancer therapy.
Biochem Pharmacol
; 63(2): 265-72, 2002 Jan 15.
Article
in English
| MEDLINE | ID: mdl-11841802
20.
Modifying rates of reductive elimination of leaving groups from indolequinone prodrugs: a key factor in controlling hypoxia-selective drug release.
Biochem Pharmacol
; 63(9): 1629-39, 2002 May 01.
Article
in English
| MEDLINE | ID: mdl-12007566