Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 20 de 37
Filter
Add more filters

Country/Region as subject
Affiliation country
Publication year range
1.
Support Care Cancer ; 28(7): 3165-3170, 2020 Jul.
Article in English | MEDLINE | ID: mdl-31707501

ABSTRACT

BACKGROUND: It is important to assess the prevalence of hypogonadism and to identify the correlation between hypogonadism and cancer treatment with quality of life (QoL) in germ cell tumor (GCT) survivors. METHODS: This is a single-center, non-randomized, prospective observational study in GCT survivors 18-50Ā years of age previously treated with surgery and chemotherapy (S+C) or surgery alone (S). Patients completed a validated QoL questionnaire at baseline, 3, and 6Ā months. Patients received supplemental testosterone as clinically indicated. Mean QoL scores were compared between two treatment groups (S+C vs. S) and within each group between survivors with hypogonadism (serum testosterone level < 300Ā ng/dL) versus without. A two-sided independent-groups t test was used to compare means. RESULTS: We evaluated 199 GCT survivors. At baseline, the prevalence of biochemical hypogonadism was 48% overall, 51% in S+C group, and 45% in S group (p = .4). Overall, there was no statistically significant difference in QoL scores between S+C and C groups, except the S+C group exhibited greater modified Aging Male Symptoms (AMS) at baseline and 6Ā months. Patients with hypogonadism reported more fatigue, poor sleep quality, and worse general health at baseline. There were no statistical differences in mean QOL scores between patients with testosterone < 300Ā ng/dL who received testosterone supplementation and who did not. CONCLUSION: A significant proportion of GCT survivors have low testosterone levels after platinum-based chemotherapy and surgery as well as with just surgery alone. GCT survivors treated with platinum-based chemotherapy exhibited more symptoms related to male aging compared with survivors treated with surgery alone.


Subject(s)
Hypogonadism/epidemiology , Neoplasms, Germ Cell and Embryonal/epidemiology , Testicular Neoplasms/epidemiology , Adult , Antineoplastic Combined Chemotherapy Protocols/therapeutic use , Cancer Survivors/statistics & numerical data , Humans , Hypogonadism/blood , Male , Middle Aged , Neoplasms, Germ Cell and Embryonal/blood , Neoplasms, Germ Cell and Embryonal/drug therapy , Neoplasms, Germ Cell and Embryonal/surgery , Organoplatinum Compounds/administration & dosage , Prevalence , Prospective Studies , Quality of Life , Surveys and Questionnaires , Testicular Neoplasms/blood , Testicular Neoplasms/drug therapy , Testicular Neoplasms/surgery , Testosterone/administration & dosage , Testosterone/blood , Young Adult
2.
Child Care Health Dev ; 39(5): 695-702, 2013 Sep.
Article in English | MEDLINE | ID: mdl-22380684

ABSTRACT

PURPOSE: Parent-adolescent shared responsibility for diabetes care is advocated by experts to achieve beneficial diabetes and psychosocial outcomes for adolescents with type 1 diabetes. Parental autonomy support may be a way to facilitate this sharing. In this dyadic study, we examined parental diabetes-specific autonomy support experienced by adolescents with type 1 diabetes and their parents (n = 89 dyads), and its association with their experience of shared diabetes care responsibility. METHODS: Path analysis was used to test an Actor-Partner Interdependence Model for parental autonomy support effects on shared responsibility. This was a secondary analysis of data from 89 parent-early/mid-adolescent dyads. RESULTS: Actor effects were identified. Parents' and adolescents' perceptions of parental autonomy support were associated with their respective reports of shared diabetes care responsibility. One partner effect was identified. Adolescents' reports of parental autonomy support were associated with parents' reports of shared responsibility. Parents and adolescents held similar views of autonomy support but discrepant views of shared responsibility. Older adolescents perceived less parental autonomy support. CONCLUSION: Increasing parental autonomy support may facilitate parent-adolescent sharing of diabetes care responsibility. Adolescent and parent perceptions influence each other and need to be considered when working with them to strengthen parental autonomy support.


Subject(s)
Diabetes Mellitus, Type 1/psychology , Parent-Child Relations , Personal Autonomy , Self Care/psychology , Adolescent , Age Factors , Child , Diabetes Mellitus, Type 1/therapy , Female , Humans , Male , Parents/psychology
3.
Child Care Health Dev ; 39(1): 61-8, 2013 Jan.
Article in English | MEDLINE | ID: mdl-22017460

ABSTRACT

BACKGROUND: Emerging adults with diabetes are assuming diabetes care responsibility, graduating from high school and leaving their parental homes. We examined: (1) how diabetes care responsibility changed in relation to time (high school to post high school) and living situation (living independently or not of parents) and (2) the association of diabetes self-efficacy, worry about hypoglycaemia, gender and glycaemic control with these changes in responsibility among emerging adults with type 1 diabetes. METHODS: During the last 6 months in high school (T1), 113 participants completed diabetes care responsibility (total, daily and non-daily), diabetes self-efficacy and worry about hypoglycaemia scales. Participants again completed the responsibility scales post high school graduation (T2). We used a linear mixed-effects model with diabetes self-efficacy, worry about hypoglycaemia, time since graduation, living situation, gender and glycaemic control as independent variables; and diabetes care responsibility (total, daily and non-daily) as dependent variables. Moderation involving diabetes self-efficacy, worry about hypoglycaemia, gender and glycaemic control was also tested. FINDINGS: Diabetes care responsibility increased over time for total (P < 0.001), daily (P= 0.002) and non-daily (P < 0.001), but the associations of self-efficacy and gender with diabetes care responsibility were moderated by living situation. Self-efficacy was negatively related to total (P= 0.006), daily (P= 0.010) and non-daily (P= 0.030) responsibility for those not living independently while positively related only to total responsibility (P= 0.028) for those living independently. Being female was positively related to total (P= 0.007) and non-daily (P= 0.001) responsibility for those living independently. CONCLUSION: Diabetes care responsibility increased from high school to post high school among these emerging adults with diabetes. There is a complex relationship between self-efficacy, gender and responsibility related to living independently of parents for these youth.


Subject(s)
Diabetes Mellitus, Type 1/psychology , Self Care/psychology , Transition to Adult Care , Adolescent , Anxiety , Blood Glucose Self-Monitoring/psychology , Diabetes Mellitus, Type 1/blood , Diabetes Mellitus, Type 1/therapy , Female , Glycated Hemoglobin/metabolism , Humans , Hypoglycemia/psychology , Indiana , Longitudinal Studies , Male , Psychometrics , Residence Characteristics , Self Efficacy , Sex Factors , Socioeconomic Factors , Young Adult
4.
Qual Saf Health Care ; 14(2): 99-106, 2005 Apr.
Article in English | MEDLINE | ID: mdl-15805454

ABSTRACT

OBJECTIVE: Electronic medical records seldom integrate performance indicators into daily operations. Assessing quality indicators traditionally requires resource intensive chart reviews of small samples. We sought to use an electronic medical record to assess use of beta-adrenergic antagonist medications (beta-blockers) following myocardial infarction, to compare a standardized manual assessment with assessment using electronic medical records, and to discuss potential for future integration of performance indicators into electronic records. DESIGN: Cross-sectional data analysis. SETTING: An urban academic medical center. PARTICIPANTS: US Medicare beneficiaries 65 years of age or older, admitted to hospital with myocardial infarction between 1995 and 1999. MEASUREMENTS AND MAIN RESULTS: Manual chart review was compared with a computer driven assessment of electronic records. Administration of beta-blockers and cases excluded from use of beta-blockers were measured, based on Medicare criteria. Among 4490 older adults, 391 (4%) of 9018 hospital admissions contained codes for myocardial infarction. In 323 (83%) of the 391 hospital admissions, criteria for excluding beta-blockers were met; 235 (60%) were excluded due to heart failure. Of 68 hospital admissions for myocardial infarction that did not meet exclusion criteria, physicians prescribed beta-blockers in 49 (72%) on admission and 42 (62%) at discharge. Compared with manual chart review, electronic review had a sensitivity of 83-100% and led to fewer false negative findings. CONCLUSIONS: An electronic medical records system can be used instead of chart review to measure use of beta-blockers after myocardial infarction. This should lead to integration of real time automated performance measurement into electronic medical records.


Subject(s)
Adrenergic beta-Antagonists/therapeutic use , Drug Utilization Review/methods , Medical Audit , Medical Records Systems, Computerized , Myocardial Infarction/drug therapy , Systems Integration , Academic Medical Centers , Aged , Cross-Sectional Studies , Hospitals, Urban , Humans , Indiana , Medicare/standards , Quality Indicators, Health Care
5.
Am J Med ; 95(5): 456-65, 1993 Nov.
Article in English | MEDLINE | ID: mdl-8238061

ABSTRACT

CASE REPORTS: Dental surgical procedures occasionally result in intrathoracic complications that may subsequently be encountered by clinicians. We report four patients with such complications, including pneumomediastinum, fatal descending necrotizing mediastinitis, and Lemierre's syndrome. In each of these patients, the commonly used dental handpiece with exhausted air directed to the working drill point was an important, but unrecognized, predisposition to their intrathoracic complication. CONCLUSION: Clinicians should be aware of the spectrum of these problems and, in particular, of the potential hazards of pressurized nonsterile air blown into open surgical sites by the dental drill.


Subject(s)
Dental Instruments/adverse effects , Root Canal Therapy/adverse effects , Thoracic Diseases/etiology , Tooth Extraction/adverse effects , Adolescent , Adult , Fatal Outcome , Female , Humans , Male , Middle Aged , Risk Factors , Root Canal Therapy/instrumentation , Tooth Extraction/instrumentation
6.
J Clin Epidemiol ; 54(9): 928-34, 2001 Sep.
Article in English | MEDLINE | ID: mdl-11520653

ABSTRACT

UNLABELLED: To estimate age group differences in the prevalence and outcomes of three common and often comorbid metabolic conditions (i.e., obesity, hypertension, and diabetes) and heart disease. DESIGN: Nationally representative prospective cohort study. SETTING: PARTICIPANTS' homes. PARTICIPANTS: 9825 adults aged 51 to 61 years (middle-age) in 1992, and 7370 adults aged 70 years and over (older-age) in 1993. MEASUREMENTS: Two-year dichotomous outcomes included: doctor visits, hospitalization, mobility difficulty, activity of daily living limitation, poor perceived health, and mortality. Odds ratios (OR) were adjusted for sociodemographic characteristics and history of cancer or lung disease. RESULTS: Those with one condition represented 80% and 70% of the middle- and older-age groups, respectively, while just 1-2% of each age group reported all three metabolic conditions. Thirteen percent and 32%, respectively, reported heart disease with or without metabolic conditions. Diabetes comorbid with other metabolic conditions, and particularly with heart disease, substantially elevated the risk of adverse outcomes such as health-related quality of life deficits, health services use, and mortality in both middle- and older-age adults. In the middle-age group, the OR was 6.81 for mortality in patients with a combination of obesity and diabetes and 6.10 in those with a combination of heart disease and diabetes. There also were significant ORs for mortality in middle-aged patients with heart disease (OR = 2.40), diabetes (OR = 2.63) and for those with a combination of obesity, hypertension, and diabetes (OR = 3.26). CONCLUSION: The impact of these often comorbid conditions underscores the importance of targeted and aggressive prevention, particularly among middle-age adults.


Subject(s)
Cardiovascular Diseases/mortality , Health Services for the Aged/statistics & numerical data , Outcome Assessment, Health Care , Quality of Life , Age Distribution , Aged , Aged, 80 and over , Cardiovascular Diseases/complications , Cohort Studies , Diabetes Complications , Diabetes Mellitus/mortality , Female , Humans , Hypertension/complications , Hypertension/mortality , Male , Middle Aged , Obesity/complications , Obesity/mortality , Odds Ratio , Prevalence , Prospective Studies , United States/epidemiology
7.
J Am Geriatr Soc ; 49(11): 1525-9, 2001 Nov.
Article in English | MEDLINE | ID: mdl-11890593

ABSTRACT

OBJECTIVES: The effectiveness of percutaneous endoscopic gastrostomy (PEG) in older adults remains controversial. Although prior studies have examined the safety of PEG and its impact on nutrition, there are limited data on the economic costs. The purpose of this study is to describe the healthcare costs associated with PEG tube feeding over 1 year. DESIGN: Prospective cohort study. SETTING: Small community of approximately 60,000 residents served by two hospital systems. PARTICIPANTS: One hundred five (70%) of 150 patients age 60 and older receiving PEG over a 24-month period in the targeted community who permitted access to their medical records. MEASUREMENTS: Patients were interviewed at baseline and every 2 months for 1 year to obtain information on use of enteral formula, complication rates, and health services use. We obtained inpatient charge data for all hospitalizations and PEG procedures for 1 year. RESULTS: Censoring patients at death or 1 year post-PEG, the mean number of days of PEG tube feeding was 180 (range 5-365). The average cost for PEG tube feeding for this cohort of patients was $7,488 (median $3,691) in 1997 and 1998. The average daily cost of PEG tube feeding was $87.21 (median $33.50). The estimated cost of providing 1 year of feeding via PEG is $31,832 (median $12,227). The main components of this cost include the initial PEG procedure (29.4%), enteral formula (24.9%), and hospital charges for major complications (33.4%). CONCLUSIONS: Direct charges associated with PEG tube feeding over 1 year are conservatively estimated at $31,832; there was considerable variation in charges because of the cost of rare but costly major complications. Also, feeding patients via PEG resulted in cost shifts in terms of the primary payor. The economic cost of PEG tube feeding is another consideration in decision making for long-term enteral feeding among older adults.


Subject(s)
Enteral Nutrition/economics , Gastroscopy/economics , Gastrostomy/economics , Health Care Costs/statistics & numerical data , Aged , Aged, 80 and over , Female , Humans , Indiana , Long-Term Care/economics , Male , Middle Aged
8.
J Am Geriatr Soc ; 49(7): 934-40, 2001 Jul.
Article in English | MEDLINE | ID: mdl-11527485

ABSTRACT

OBJECTIVE: To assess the impact of cognitive impairment on mortality in older primary care patients after controlling for confounding effects of demographic and comorbid chronic conditions. DESIGN: Prospective cohort study. SETTING: Academic primary care group practice. PARTICIPANTS: Three thousand nine hundred and fifty-seven patients age 60 and older who completed the Short Portable Mental Status Questionnaire (SPMSQ) during routine office visits. MEASUREMENTS: Cognitive impairment measured at baseline using the SPMSQ, demographics, problem drinking, history of smoking, clinical data (including weight, cholesterol level, and serum albumin), and comorbid chronic conditions collected at baseline; survival time measured during the 5 to 7 years after baseline. RESULTS: Eight hundred and eighty-six patients (22.4%) died during the 5 to 7 years of follow-up. Cognitive impairment was categorized as having no impairment (84.3%), mild impairment (10.5%), and moderate-to-severe impairment (5.2%) based on SPMSQ score. Chi-square tests revealed that patients with moderate-to-severe impairment were significantly more likely to die compared with patients with mild impairment (40.8% vs 21.5%) and those with no impairment (40.8% vs 21.4%). No significant difference in crude mortality was found between patients with no impairment and those with mild impairment. After analyzing time to death using the Kaplan-Meier method, patients with moderate-to-severe cognitive impairment were at increased risk of death compared with those with no or mild impairment (Log-rank chi(2) = 55.5; P <.0001). Even in multivariable analyses using Cox proportional hazards to control for confounding factors, compared with those with no impairment, moderately-to-severely impaired patients had an increased risk of death, with a hazard ratio (HR) of 1.70. Increased risk of death was also associated with older age (HR = 1.03 for each year), a history of smoking (HR = 1.48), having a serum albumin level <3.5 g/L (HR = 1.29), and weighing less than 90% of the ideal body weight (HR = 1.98). Outpatient diagnoses associated with increased mortality risk were diabetes mellitus, coronary artery disease, congestive heart failure, cerebrovascular disease, cancer, anemia, and chronic obstructive pulmonary disease (HR range 1.36-1.67). Factors protective of mortality risk included female gender (HR = 0.67) and black race (HR = 0.73). CONCLUSIONS: Moderate-to-severe cognitive impairment is associated with an increased risk of mortality, even after controlling for confounding effects of demographic and clinical characteristics. Mild cognitive impairment is not associated with mortality risk, but a longer follow-up period may be necessary to identify this risk if it exists.


Subject(s)
Aged/statistics & numerical data , Cognition Disorders/complications , Cognition Disorders/mortality , Family Practice/statistics & numerical data , Group Practice/statistics & numerical data , Primary Health Care/statistics & numerical data , Academic Medical Centers , Cognition Disorders/classification , Cognition Disorders/diagnosis , Comorbidity , Confounding Factors, Epidemiologic , Female , Geriatric Assessment , Humans , Indiana/epidemiology , Male , Mass Screening , Mental Status Schedule , Multivariate Analysis , Proportional Hazards Models , Prospective Studies , Risk Factors , Severity of Illness Index , Surveys and Questionnaires , Survival Analysis
9.
J Am Geriatr Soc ; 45(5): 558-63, 1997 May.
Article in English | MEDLINE | ID: mdl-9158575

ABSTRACT

OBJECTIVES: To estimate the independent effect of hospitalization for congestive heart failure (CHF) on subsequent mortality, readmission for CHF, rehospitalization for any reason, and change in functional status. DESIGN: Secondary analysis of the nationally representative Longitudinal Study on Aging, Baseline (1984) interview data are linked to Medicare hospitalization and death records for 1984-1991 and to functional status reports at three biennial follow-ups. SETTING: In-home and telephone interviews. PARTICIPANTS: a total of 7527 noninstitutionalized older adults aged 70 years or older at baseline. MEASUREMENTS: Hospitalization for CHF was defined as having one or more episodes with primary or secondary discharge ICD9-CM codes of 428. Multivariable proportional hazards, logistic and linear regression, as well as multiple classification analysis, were used to estimate the independent effects of having been hospitalized for CHF. RESULTS: The adjusted risk ratios for having a primary or secondary hospital discharge diagnosis of CHF on mortality (compared with not having any CHF hospital discharge diagnoses) were 1.58 (CI95% = 1.40 to 1.78) and 1.29 (CI95% = 1.15 to 1.45), respectively (P < .001). CHF readmission and rehospitalization rates were substantial, ranging from 16.0 to 47.5% at 1 year, depending on the criteria employed. The adjusted odds ratios for having any subsequent hospitalizations associated with having a primary or secondary hospital discharge diagnosis of CHF (compared with not having any CHF hospital discharge diagnoses) were 7.70 (CI95% = 6.20 to 9.57) and 2.99 (CI95% = 2.51 to 3.56), respectively (P < .001). The percent increases in the number of hospital episodes, total charges, and total length of stay attributable to having been hospitalized for CHF were significant (P < .001) and ranged from 15.5 to 66.7%. Having been hospitalized for CHF was also related significantly to greater increases in the mean number of functional limitations at follow-up. CONCLUSION: Hospitalization for CHF among older adults increases substantially the risk of subsequent mortality, readmission for CHF, rehospitalization for any reason, and greater functional decline. Therefore, greater attention to the prevention and management of CHF is needed.


Subject(s)
Heart Failure/mortality , Hospitalization , Patient Readmission/statistics & numerical data , Activities of Daily Living , Aged , Catchment Area, Health , Data Collection , Female , Heart Failure/therapy , Humans , Length of Stay , Longitudinal Studies , Male
10.
J Am Geriatr Soc ; 46(11): 1371-7, 1998 Nov.
Article in English | MEDLINE | ID: mdl-9809758

ABSTRACT

BACKGROUND: Urban academic medical centers provide care for large populations of vulnerable older adults. These patients often suffer a disproportionate share of chronic illnesses, disabilities, and social stressors that may increase health care costs. OBJECTIVE: To describe the distribution and content of total healthcare costs accrued over a 4-year period by a community of older adults cared for in an urban academic healthcare system and to describe high-cost patients and utilization patterns. DESIGN: A cohort study. SETTING: A tax-supported public healthcare system consisting of a 450-bed hospital and seven community-based ambulatory care centers. PATIENTS: 12,581 patients aged 60 years and older who had at least two ambulatory visits and/or one hospitalization within the healthcare system from 1993 through 1995. MEASUREMENTS: Patient demographic and clinical characteristics, hospital and ambulatory utilization rates, and all healthcare costs accrued from 1993 through 1996 were determined. Costs were estimated from the perspective of the healthcare system using cost to charge ratios. MAIN RESULTS: The mean patient age was 70 years, 60% were women, 44% were Black, and 83% were covered by Medicare and/or Medicaid. Nearly 25% of patients were obese, 15.8% had a history of smoking, and 15.5% had evidence of malnutrition. The mean number of ambulatory visits per year was 4.3 (+/-7.2), and 38.1% of patients had been hospitalized one or more times. Within the 4-year window, 24.1% of patients had missed five or more appointments with their primary care physicians, 32.7% of patients had five or more unscheduled clinic visits, and 12.5% had five or more emergency room visits. Total health care costs for 4 years for this cohort of older adults was $125.2 million dollars, with per capita annual mean costs of $3893. Expenditures associated with hospitalizations accounted for 63.6% of healthcare costs. Total inpatient and outpatient costs for the 38% of patients hospitalized at least once accounted for 85.3% of all health care expenditures. Patients who died in the hospital did not accrue significantly greater costs than patients who died out of the hospital. Simulations of a random 5% adverse selection of high-cost patients among two capitated systems resulted in cost shifts of $11.1 million. Recorded smoking history, obesity, and low serum albumin were significantly associated with excess costs. CONCLUSIONS: Healthcare costs are concentrated in a significant minority of older adults. Costs accrued in conjunction with hospital stays dominate healthcare expenditures for this cohort of older adults. However, most older adults (83%) have one or fewer hospital episodes in a 4-year period. Although patients who died accrued greater healthcare costs, these costs were not higher when the death occurred in the hospital. Self-care behaviors are an important target for interventions to reduce costs.


Subject(s)
Academic Medical Centers/economics , Health Care Costs/statistics & numerical data , Health Services for the Aged/economics , Urban Health Services/economics , Academic Medical Centers/statistics & numerical data , Academic Medical Centers/trends , Aged , Cohort Studies , Community Health Centers/economics , Community Health Centers/statistics & numerical data , Community Health Centers/trends , Female , Health Care Costs/trends , Health Services for the Aged/statistics & numerical data , Health Services for the Aged/trends , Hospital Costs/statistics & numerical data , Hospital Costs/trends , Humans , Indiana , Male , Middle Aged , Regression Analysis , Urban Health Services/statistics & numerical data , Urban Health Services/trends
11.
J Am Geriatr Soc ; 48(7): 760-8, 2000 Jul.
Article in English | MEDLINE | ID: mdl-10894314

ABSTRACT

OBJECTIVES: The amount of medication dispensed to older adults for the treatment of chronic disease must be balanced carefully. Insufficient medication supplies lead to inadequate treatment of chronic disease, whereas excessive supplies represent wasted resources and the potential for toxicity. We used an electronic medical record system to determine the distribution of medications supplied to older urban adults and to examine the correlations of these distributions with healthcare costs and use. DESIGN: A cross-sectional study using data acquired over 3 years (1994-1996). SETTING: A tax-supported urban public healthcare system consisting of a 300-bed hospital, an emergency department, and a network of community-based ambulatory care centers. PATIENTS: Patients were >60 years of age and had at least one prescription refill and at least two ambulatory visits or one hospitalization during the 3-year period. MEASUREMENTS: Focusing on 12 major categories of drugs used to treat chronic diseases, we determined the amounts and direct costs of these medications dispensed to older adult patients. Amounts of medications that were needed by patients to medicate themselves adequately were compared with the medication supply actually dispensed considering all sources of care (primary, emergency, and inpatient). We calculated the excess drug costs attributable to oversupply of medication (>120% of the amount needed) and the drug cost reduction caused by undersupply of medication (<80% of the amount needed). We also compared total healthcare use and costs for patients who had an oversupply, an undersupply, or an appropriate supply of their medications. RESULTS: The cohort comprised 4164 patients with a mean age of 71 +/- 7 (SD) who received a mean of 3 +/- 2 (SD) drugs for chronic conditions. There were 668 patients (16%) who received <80% of the supply needed, 1556 patients (37%) who received between 80 and 120% of the supply needed, and 1940 patients (47%) who received >120% of the supply needed. The total direct cost of targeted medications for 3 years was $1.96 million or, on average, $654,000 annually. During the 3-year period, patients receiving >120% of their needed medications had excess direct medication costs of $279,084 or $144 per patient, whereas patients receiving <80% of drugs needed had reduced medication costs of $423,438 or $634 per patient. Multivariable analyses revealed that both under- and over-supplies of medication were associated with a greater likelihood of emergency department visits and hospital admissions. CONCLUSIONS: More than one-half of the older adults in our study have under- or over-supplies of medications for the treatment of their chronic diseases. Such inappropriate supplies of medications are associated with healthcare utilization and costs.


Subject(s)
Chronic Disease/economics , Drug Costs/statistics & numerical data , Health Services for the Aged/economics , Pharmaceutical Preparations/supply & distribution , Urban Health , Adult , Aged , Chronic Disease/drug therapy , Cost-Benefit Analysis , Cross-Sectional Studies , Female , Health Care Costs , Humans , Indiana , Male , Middle Aged , Patient Admission/economics , Uncompensated Care/economics
12.
J Am Geriatr Soc ; 48(9): 1048-54, 2000 Sep.
Article in English | MEDLINE | ID: mdl-10983903

ABSTRACT

OBJECTIVE: Percutaneous endoscopic gastrostomy (PEG) has become the preferred method to provide enteral tube feeding to older adults who have difficulty eating, but the impact of PEG on patient outcomes is poorly understood. The objective of this study was to describe changes in nutrition, functional status, and health-related quality of life among older adults receiving PEG. DESIGN: A prospective cohort study. SETTING: A small community of approximately 60,000 residents served by two hospital systems. PARTICIPANTS: One hundred fifty patients aged 60 and older receiving PEG from one of the four gastroenterologists practicing in the targeted community. MEASUREMENTS: Patients were assessed at baseline and every 2 months for 1 year to obtain clinical characteristics, process of care data, physical and cognitive function, subjective health status, nutritional status, complications, and mortality. RESULTS: Over a 14-month period, 150 patients received PEG tubes in the targeted community; the mean age was 78.9. The most frequent indications for the PEG were stroke (40.7%), neurodegenerative disorders (34.7%), and cancer (13.3%). All measures of functional status, cognitive status, severity of illness, comorbidity, and quality of life demonstrated profound and life-threatening impairment; 30-day mortality was 22% and 1-year mortality was 50%. Among patients surviving 60 days or more, at least 70% had no significant improvement in functional, nutritional, or subjective health status. Serious complications were rare, but most patients experienced symptomatic problems that they attributed to the enteral tube feeding. CONCLUSIONS: PEG tube feeding in severely and chronically ill older adults can be accomplished safely. However, there are important patient burdens associated with the PEG and there was limited evidence that the procedure improves functional, nutritional, or subjective health status in this cohort of older adults. The issues raised in this descriptive study provide impetus for a randomized trial of PEG tube feeding compared with alternative methods of patient care for older adults with difficulty eating.


Subject(s)
Activities of Daily Living , Gastroscopy , Gastrostomy , Nutritional Status , Quality of Life , Age Factors , Aged , Aged, 80 and over , Attitude to Health , Enteral Nutrition/adverse effects , Enteral Nutrition/mortality , Enteral Nutrition/psychology , Female , Gastroscopy/adverse effects , Gastroscopy/mortality , Gastroscopy/psychology , Gastrostomy/adverse effects , Gastrostomy/mortality , Gastrostomy/psychology , Geriatric Assessment , Humans , Male , Middle Aged , Outcome and Process Assessment, Health Care , Prospective Studies , Survival Analysis , Treatment Outcome
13.
J Gerontol A Biol Sci Med Sci ; 52(2): M97-105, 1997 Mar.
Article in English | MEDLINE | ID: mdl-9060977

ABSTRACT

BACKGROUND: The purpose of the study was to estimate the prevalence of sociodemographic, health behavior, chronic disease, and impairment factors and their impact on difficulty in lower body function among two age-cohorts (51-61 and 71-81 years) of Mexican Americans, African Americans, and Whites. METHODS: Reports from 8,727 and 4,510 self-respondents of the 1992 baseline Health and Retirement Survey and the 1993 baseline Assets and Health Dynamics Study, respectively, were used to estimate prevalence. Multiple linear regression of the 4-item lower body difficulty scale (alpha = .80) was used to estimate the direct effects of the risk factors within the age-cohort and ethnicity groups. RESULTS: Overall, the risk factors are more prevalent among both minority groups and the older age-cohort. Lower body deficits are particularly high among Mexican Americans and the younger age-cohort of African Americans. The impact of risk factors does not vary much by ethnicity or age-cohort. Female gender, pain, arthritis, and heart and lung disease are the major risk factors, and they account for about one-third of the variance in lower body difficulty for each group. CONCLUSIONS: Efforts to prevent or reduce lower body difficulty should pay particular attention to pain, arthritis, and heart and lung disease. The central role of sociodemographic and behavioral factors in chronic disease argues for their continued inclusion in disability modeling and prevention.


Subject(s)
Black or African American , Mexican Americans , White People , Aged , Aged, 80 and over , Chronic Disease , Cohort Studies , Disabled Persons , Disease , Female , Health Behavior , Humans , Male , Memory Disorders , Middle Aged , Prevalence , Risk Factors , Socioeconomic Factors
14.
Gerontologist ; 35(2): 150-61, 1995 Apr.
Article in English | MEDLINE | ID: mdl-7750771

ABSTRACT

Mortality risks over an 8-year period are assessed among the 7,527 older adults interviewed as part of the Longitudinal Study on Aging. Using a modified version of the behavioral model, hierarchical methods are used to sequentially introduce the predisposing and enabling characteristics, disease history, disabilities and functional limitations, perceived health, and health services utilization both at and after baseline. Based on their partial r statistics (shown in parentheses), the proportional hazard analyses identify the mean annual number of hospital episodes after baseline (.13), age (.07), female gender (-.05), non-kin social supports (-.03), body mass (-.03), and having a history of diabetes (.03) as the six most salient predictors. These six variables account for 80% of the overall model fit.


Subject(s)
Models, Statistical , Mortality , Activities of Daily Living , Aged , Female , Health Services/statistics & numerical data , Health Status , Humans , Longitudinal Studies , Odds Ratio , Proportional Hazards Models , Risk Factors , United States/epidemiology
15.
Gerontologist ; 35(4): 451-62, 1995 Aug.
Article in English | MEDLINE | ID: mdl-7557515

ABSTRACT

The antecedents and consequences of four markers of physical activity and exercise are examined for the 6,780 baseline self-respondents to the Longitudinal Study on Aging. These dichotomous markers reflect having a level of physical activity greater than one's peers (45.8%), getting as much exercise as needed (58.9%), having a regular exercise routine (28.4%), and walking a mile or more at least once a week (29.9%). The major factors associated with engaging in these behaviors are having fewer lower body limitations, better perceived health, more non-kin social supports, not worrying about one's health, and having a sense of control over one's health. When added to traditional models predicting subsequent (over the next 6 to 8 years) mortality, nursing home placement, hospital resource consumption, and changes in functional status, the four markers of physical activity and exercise have numerous statistically and substantively significant associations, all of which involve better health outcomes.


Subject(s)
Exercise , Health Status , Aged , Exercise/psychology , Female , Humans , Male , Models, Psychological , Multivariate Analysis , Odds Ratio , United States
16.
J Gerontol B Psychol Sci Soc Sci ; 51(4): S217-20, 1996 Jul.
Article in English | MEDLINE | ID: mdl-8673651

ABSTRACT

Older adults are expected and frequently found to report less control than younger adults. In this study, we decompose this negative relationship between age and sense of control using nested multivariable linear regression models that serially introduce sociodemographic characteristics, socioeconomic factors, health status, and subjective religiosity and religious beliefs in a sample of 1,051 older adults attending the general medicine clinics of a major medical center. The results indicate that the effect of age is suppressed in the bivariable model. In the final multivariable model, educational attainment has the largest relative effect (i.e., beta; .253), followed by age (-.210), mental health (.174), subjective religiosity (.113), being an African American (-.100), perceived health (.082), and being Catholic (.068). Future research should focus on the inflection point in the relationship between age and the sense of control that apparently occurs at about 50 years of age.


Subject(s)
Aging , Aged , Educational Status , Female , Humans , Life Change Events , Male , Middle Aged
17.
J Gerontol B Psychol Sci Soc Sci ; 50(1): S45-S58, 1995 Jan.
Article in English | MEDLINE | ID: mdl-7757830

ABSTRACT

Although much is known from cross-sectional studies about the use of physician services among older adults, little is known about the consistency of or changes in that utilization over time. Hierarchical multivariable regression analysis of data on the 2,430 older adults who were enrolled in the LSOA and successfully reinterviewed in 1986, 1988, and 1990 is used to model changes in the number of physician visits between 1984 and 1990 based on the predisposing, enabling, and need (including functional status) characteristics measured in 1984, and subsequent changes in functional status. Overall, 19 percent of the variance in physician utilization is explained, with 8 percent coming from the introduction of the need characteristics, 4.7 percent from the subsequent introduction of the number of physician visits at baseline, and 4.9 percent from the subsequent introduction of changes in functional status. Declines in each of the functional status measures are significantly associated with increases in physician utilization, although improvements are fundamentally unrelated.


Subject(s)
Physicians/statistics & numerical data , Activities of Daily Living , Aged , Ambulatory Care/statistics & numerical data , Ambulatory Care/trends , Female , Health Status , Humans , Longitudinal Studies , Male , Models, Psychological , Multivariate Analysis , Office Visits/statistics & numerical data , Office Visits/trends , Regression Analysis
18.
J Gerontol B Psychol Sci Soc Sci ; 50(2): S88-100, 1995 Mar.
Article in English | MEDLINE | ID: mdl-7757844

ABSTRACT

Medicare claims data are used to model hospital utilization patterns for the 4,660 survivors and 2,867 decedents of the Longitudinal Study on Aging (LSOA). When the volume of hospital utilization was collapsed into four categories based on the mean annual number of hospital episodes and consistency was defined as a maximum absolute deviation from that mean of 1.5 or less, 42.6 percent of the LSOA respondents were found not to have any hospital admissions, and another 24.7 percent were found to be consistently low users. Only 4.8 percent were consistently high users, with an additional 6.8 percent being inconsistently high users. Multiple regression identified prior physician and hospital utilization, as well as poor perceived health, as the most important predictors of the volume and consistency of hospital utilization among survivors, as well as of the volume of hospital utilization among decedents. Among decedents, consistency was primarily related to geographic region and prior physician utilization.


Subject(s)
Hospitalization/statistics & numerical data , Hospitals/statistics & numerical data , Activities of Daily Living , Aged , Episode of Care , Female , Health Status , Humans , Longitudinal Studies , Male , Models, Psychological , Multivariate Analysis , Physicians/statistics & numerical data , Regression Analysis , Survivors/statistics & numerical data , United States/epidemiology
19.
J Gerontol B Psychol Sci Soc Sci ; 52 Spec No: 49-60, 1997 May.
Article in English | MEDLINE | ID: mdl-9215357

ABSTRACT

Activities of daily living (ADLs), instrumental ADLs, and disability markers have traditionally been the most common indicators of functional status. The study on Asset and Health Dynamics Among the Oldest Old (AHEAD) is used to replicate a five-dimensional measurement model composed of these observable indicators among the older adult self-respondents. The items available to measure upper body disability were found wanting, but the lower body disability, and the basic, household, and advanced ADL constructs were confirmed. Analyses of the measurement model separately among subgroups of women, men, Hispanics, Mexican Americans, African Americans, and Whites found no meaningful differences. Two structural models linking the lower body disability, and the basic, household, and advanced ADL constructs to perceived health and depression were also replicated among the older adult self-respondents, as well as separately among African Americans and among Whites. These models reaffirmed the dominant role of lower body disability on the everyday activities of older adults, and on their perceived health and depression.


Subject(s)
Activities of Daily Living , Aged , Black or African American , Health Status , Hispanic or Latino , White People , Aged, 80 and over , Female , Geriatric Assessment , Humans , Male , Models, Theoretical , Socioeconomic Factors , United States
20.
J Aging Health ; 9(1): 28-42, 1997 Feb.
Article in English | MEDLINE | ID: mdl-10182409

ABSTRACT

Activity of daily living (ADL) and instrumental ADL (IADL) data from the 1989 National Long-Term Care Survey (NLTCS) are used to replicate two domains of functional status with a total of five dimensions among them. LISREL analysis of the 14,415 Black and White older adults obtained from the 1989 NLTCS screen replicates three ADL disability dimensions (basic, household, and advanced) with few modifications, except among Black males. Similarly, analysis of the 4,297 Black and White disabled older adults replicates five functional status dimensions (3 ADL disability dimensions plus lower- and upper-body functional limitation dimensions) with few modifications, except among Black males. These results suggest that improved understanding of functional status will occur from studies that take into consideration the differences between functional limitation and ADL disability. The results also indicate that further research on the validity of functional reports among Black males is needed.


Subject(s)
Black or African American , Disability Evaluation , White People , Activities of Daily Living , Aged , Female , Health Status Indicators , Humans , Male , Models, Theoretical , Sex Factors , United States
SELECTION OF CITATIONS
SEARCH DETAIL