Subject(s)
Analgesics, Opioid , Anti-Inflammatory Agents, Non-Steroidal , Clonidine , Diclofenac , Low Back Pain , Tramadol , Humans , Clonidine/therapeutic use , Clonidine/analogs & derivatives , Tramadol/therapeutic use , Tramadol/adverse effects , Low Back Pain/drug therapy , Diclofenac/therapeutic use , Diclofenac/administration & dosage , Anti-Inflammatory Agents, Non-Steroidal/therapeutic use , Anti-Inflammatory Agents, Non-Steroidal/administration & dosage , Analgesics, Opioid/therapeutic use , Analgesics, Opioid/administration & dosage , Drug Therapy, Combination , Acute Pain/drug therapy , Male , FemaleABSTRACT
Brain abscesses are uncommon in children. We report a 3-year-old, previously healthy and immunocompetent boy, with an Absidia brain abscess. He presented with decreased sensorium and status epilepticus. The brain abscess was detected using cranial computed tomography and magnetic resonance imaging, and the diagnosis was confirmed with pus and brain tissue cultures. The patient responded to surgical drainage with concomitant intravenous and intraventricular amphotericin B.
Subject(s)
Amphotericin B/therapeutic use , Brain Abscess/therapy , Mucormycosis/drug therapy , Absidia/isolation & purification , Amphotericin B/administration & dosage , Antifungal Agents/administration & dosage , Antifungal Agents/therapeutic use , Brain Abscess/diagnosis , Brain Abscess/microbiology , Child, Preschool , Drainage/methods , Humans , Immunocompetence , Injections, Intraventricular , Male , Mucormycosis/microbiologyABSTRACT
Spinal injury often affects young adults and results in debilitating neurological status, which in turn places a significant burden on society. This review article describes the current practice and controversies surrounding the management of spinal injury. General principles of pre-hospital management, resuscitation, medical treatment, surgical intervention and future advancement are reviewed.
Subject(s)
Spinal Injuries/therapy , Emergency Medical Services/methods , Extremities/blood supply , Extremities/pathology , Humans , Pulmonary Embolism/etiology , Pulmonary Embolism/prevention & control , Spinal Injuries/complications , Spinal Injuries/diagnosis , Spinal Injuries/drug therapy , Spinal Injuries/surgery , Venous Thrombosis/etiology , Venous Thrombosis/prevention & controlABSTRACT
The purpose of this paper is to study the efficacy of applying stereotactic navigation guidance to nasopharyngectomy via a minimally invasive transnasal approach as compared with the conventional open transfacial approaches. The nasopharynx is the centre of the anterior skull base, which is remote from the surface of the facial skeleton. It is well known that there are several surgical approaches for access to resect tumours from the nasopharynx. However, the open techniques have been associated with much morbidity and only provide access to, and identification of, the ipsilateral internal carotid artery that forms the lateral boundary and resection limit of the nasopharynx. The coupling of stereotactic navigation guidance and a minimally invasive transnasal approach for nasopharyngectomy allows the surgeon to identify and protect the internal carotid artery bilaterally at the nasopharynx. This technique reduces operating time and morbidity to a minimum and yet is oncologically sound for resecting nasopharyngeal lesions. We compare 15 patients who underwent the stereotactic navigation guidance approach with 20 patients who received a conventional open transfacial approach.