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1.

CRISPR screens in cancer spheroids identify 3D growth-specific vulnerabilities.

Han, Kyuho; Pierce, Sarah E; Li, Amy; Spees, Kaitlyn; Anderson, Gray R; Seoane, Jose A; Lo, Yuan-Hung; Dubreuil, Michael; Olivas, Micah; Kamber, Roarke A; Wainberg, Michael; Kostyrko, Kaja; Kelly, Marcus R; Yousefi, Maryam; Simpkins, Scott W; Yao, David; Lee, Keonil; Kuo, Calvin J; Jackson, Peter K; Sweet-Cordero, Alejandro; Kundaje, Anshul; Gentles, Andrew J; Curtis, Christina; Winslow, Monte M; Bassik, Michael C.

Nature ; 580(7801): 136-141, 2020 04.

Article in English | MEDLINE | ID: mdl-32238925

2.

Twist1 suppresses senescence programs and thereby accelerates and maintains mutant Kras-induced lung tumorigenesis.

Tran, Phuoc T; Shroff, Emelyn H; Burns, Timothy F; Thiyagarajan, Saravanan; Das, Sandhya T; Zabuawala, Tahera; Chen, Joy; Cho, Yoon-Jae; Luong, Richard; Tamayo, Pablo; Salih, Tarek; Aziz, Khaled; Adam, Stacey J; Vicent, Silvestre; Nielsen, Carsten H; Withofs, Nadia; Sweet-Cordero, Alejandro; Gambhir, Sanjiv S; Rudin, Charles M; Felsher, Dean W.

PLoS Genet ; 8(5): e1002650, 2012.

Article in English | MEDLINE | ID: mdl-22654667

3.

An oncogenic KRAS2 expression signature identified by cross-species gene-expression analysis.

Sweet-Cordero, Alejandro; Mukherjee, Sayan; Subramanian, Aravind; You, Han; Roix, Jeffrey J; Ladd-Acosta, Christine; Mesirov, Jill; Golub, Todd R; Jacks, Tyler.

Nat Genet ; 37(1): 48-55, 2005 Jan.

Article in English | MEDLINE | ID: mdl-15608639

4.

HIF-2alpha deletion promotes Kras-driven lung tumor development.

Mazumdar, Jolly; Hickey, Michele M; Pant, Dhruv K; Durham, Amy C; Sweet-Cordero, Alejandro; Vachani, Anil; Jacks, Tyler; Chodosh, Lewis A; Kissil, Joseph L; Simon, M Celeste; Keith, Brian.

Proc Natl Acad Sci U S A ; 107(32): 14182-7, 2010 Aug 10.

Article in English | MEDLINE | ID: mdl-20660313

5.

Detection of a GLIS3 fusion in an infant with AML refractory to chemotherapy.

Smith, Stephen M; Lee, Alex; Tong, Schuyler; Leung, Stanley; Hongo, Henry; Rivera, Jose; Sweet-Cordero, Alejandro; Michlitsch, Jennifer; Stieglitz, Elliot.

Cold Spring Harb Mol Case Stud ; 2022 Aug 04.

Article in English | MEDLINE | ID: mdl-35927023

6.

APOBEC Mutational Signature and Tumor Mutational Burden as Predictors of Clinical Outcomes and Treatment Response in Patients With Advanced Urothelial Cancer.

Natesan, Divya; Zhang, Li; Martell, Henry J; Jindal, Tanya; Devine, Patrick; Stohr, Bradley; Espinosa-Mendez, Carlos; Grenert, James; Van Ziffle, Jessica; Joseph, Nancy; Umetsu, Sarah; Onodera, Courtney; Turski, Michelle; Chan, Emily; Desai, Arpita; Aggarwal, Rahul; Wong, Anthony; Porten, Sima; Chou, Jonathan; Friedlander, Terence; Fong, Lawrence; Small, Eric J; Sweet-Cordero, Alejandro; Koshkin, Vadim S.

Front Oncol ; 12: 816706, 2022.

Article in English | MEDLINE | ID: mdl-35321431

7.

MicroRNA expression profiles classify human cancers.

Lu, Jun; Getz, Gad; Miska, Eric A; Alvarez-Saavedra, Ezequiel; Lamb, Justin; Peck, David; Sweet-Cordero, Alejandro; Ebert, Benjamin L; Mak, Raymond H; Ferrando, Adolfo A; Downing, James R; Jacks, Tyler; Horvitz, H Robert; Golub, Todd R.

Nature ; 435(7043): 834-8, 2005 Jun 09.

Article in English | MEDLINE | ID: mdl-15944708

8.

Requirement for Rac1 in a K-ras induced lung cancer in the mouse.

Kissil, Joseph L; Walmsley, Marita J; Hanlon, Linda; Haigis, Kevin M; Bender Kim, Carla F; Sweet-Cordero, Alejandro; Eckman, Matthew S; Tuveson, David A; Capobianco, Anthony J; Tybulewicz, Victor L J; Jacks, Tyler.

Cancer Res ; 67(17): 8089-94, 2007 Sep 01.

Article in English | MEDLINE | ID: mdl-17804720

9.

The present and the future of the RAS pathway: From function and genomics to inhibition.

Gil-Bazo, Ignacio; Sweet-Cordero, Alejandro; Vicent, Silvestre.

Cancer Biol Ther ; 17(7): 719-22, 2016 07 02.

Article in English | MEDLINE | ID: mdl-27212457

10.

The second European interdisciplinary Ewing sarcoma research summit--A joint effort to deconstructing the multiple layers of a complex disease.

Kovar, Heinrich; Amatruda, James; Brunet, Erika; Burdach, Stefan; Cidre-Aranaz, Florencia; de Alava, Enrique; Dirksen, Uta; van der Ent, Wietske; Grohar, Patrick; Grünewald, Thomas G P; Helman, Lee; Houghton, Peter; Iljin, Kristiina; Korsching, Eberhard; Ladanyi, Marc; Lawlor, Elizabeth; Lessnick, Stephen; Ludwig, Joseph; Meltzer, Paul; Metzler, Markus; Mora, Jaume; Moriggl, Richard; Nakamura, Takuro; Papamarkou, Theodore; Radic Sarikas, Branka; Rédini, Francoise; Richter, Guenther H S; Rossig, Claudia; Schadler, Keri; Schäfer, Beat W; Scotlandi, Katia; Sheffield, Nathan C; Shelat, Anang; Snaar-Jagalska, Ewa; Sorensen, Poul; Stegmaier, Kimberly; Stewart, Elizabeth; Sweet-Cordero, Alejandro; Szuhai, Karoly; Tirado, Oscar M; Tirode, Franck; Toretsky, Jeffrey; Tsafou, Kalliopi; Üren, Aykut; Zinovyev, Andrei; Delattre, Olivier.

Oncotarget ; 7(8): 8613-24, 2016 Feb 23.

Article in English | MEDLINE | ID: mdl-26802024

11.

Preclinical Models Provide Scientific Justification and Translational Relevance for Moving Novel Therapeutics into Clinical Trials for Pediatric Cancer.

Langenau, David M; Sweet-Cordero, Alejandro; Wechsler-Reya, Robert; Dyer, Michael A.

Cancer Res ; 75(24): 5176-5186, 2015 Dec 15.

Article in English | MEDLINE | ID: mdl-26627009

12.

MEK1/2 inhibition elicits regression of autochthonous lung tumors induced by KRASG12D or BRAFV600E.

Trejo, Christy L; Juan, Joseph; Vicent, Silvestre; Sweet-Cordero, Alejandro; McMahon, Martin.

Cancer Res ; 72(12): 3048-59, 2012 Jun 15.

Article in English | MEDLINE | ID: mdl-22511580

13.

New insights into oncogenic stress.

Haigis, Kevin M; Sweet-Cordero, Alejandro.

Nat Genet ; 43(3): 177-8, 2011 Mar.

Article in English | MEDLINE | ID: mdl-21350495

14.

Discovery and preclinical validation of drug indications using compendia of public gene expression data.

Sirota, Marina; Dudley, Joel T; Kim, Jeewon; Chiang, Annie P; Morgan, Alex A; Sweet-Cordero, Alejandro; Sage, Julien; Butte, Atul J.

Sci Transl Med ; 3(96): 96ra77, 2011 Aug 17.

Article in English | MEDLINE | ID: mdl-21849665

15.

Expression and silencing of the microtubule-associated protein Tau in breast cancer cells.

Spicakova, Tatiana; O'Brien, Maureen M; Duran, George E; Sweet-Cordero, Alejandro; Sikic, Branimir I.

Mol Cancer Ther ; 9(11): 2970-81, 2010 Nov.

Article in English | MEDLINE | ID: mdl-21062914

16.

Hypoxia in models of lung cancer: implications for targeted therapeutics.

Graves, Edward E; Vilalta, Marta; Cecic, Ivana K; Erler, Janine T; Tran, Phuoc T; Felsher, Dean; Sayles, Leanne; Sweet-Cordero, Alejandro; Le, Quynh-Thu; Giaccia, Amato J.

Clin Cancer Res ; 16(19): 4843-52, 2010 Oct 01.

Article in English | MEDLINE | ID: mdl-20858837

17.

New insights into tumor suppressors.

Marques, Michelle; Sweet-Cordero, Alejandro.

Genome Biol ; 9(9): 320, 2008.

Article in English | MEDLINE | ID: mdl-18828882

18.

Differential effects of oncogenic K-Ras and N-Ras on proliferation, differentiation and tumor progression in the colon.

Haigis, Kevin M; Kendall, Krystle R; Wang, Yufang; Cheung, Ann; Haigis, Marcia C; Glickman, Jonathan N; Niwa-Kawakita, Michiko; Sweet-Cordero, Alejandro; Sebolt-Leopold, Judith; Shannon, Kevin M; Settleman, Jeffrey; Giovannini, Marco; Jacks, Tyler.

Nat Genet ; 40(5): 600-8, 2008 May.

Article in English | MEDLINE | ID: mdl-18372904

19.

Comparison of gene expression and DNA copy number changes in a murine model of lung cancer.

Sweet-Cordero, Alejandro; Tseng, George C; You, Han; Douglass, Margaret; Huey, Bing; Albertson, Donna; Jacks, Tyler.

Genes Chromosomes Cancer ; 45(4): 338-48, 2006 Apr.

Article in English | MEDLINE | ID: mdl-16323170

20.

Avances en el diagnóstico molecular de las enfermedades infecciosas y parasitarias / Advances in the molecular diagnosis of infectious and parasitic diseases

Sweet Cordero, Alejandro; Santos Preciado, José Ignacio.

Gac. méd. Méx ; 133(supl.1): 111-24, 1997. ilus

Article in Spanish | LILACS | ID: lil-226987

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