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1.

Inhibition of Dihydroorotate Dehydrogenase Overcomes Differentiation Blockade in Acute Myeloid Leukemia.

Sykes, David B; Kfoury, Youmna S; Mercier, François E; Wawer, Mathias J; Law, Jason M; Haynes, Mark K; Lewis, Timothy A; Schajnovitz, Amir; Jain, Esha; Lee, Dongjun; Meyer, Hanna; Pierce, Kerry A; Tolliday, Nicola J; Waller, Anna; Ferrara, Steven J; Eheim, Ashley L; Stoeckigt, Detlef; Maxcy, Katrina L; Cobert, Julien M; Bachand, Jacqueline; Szekely, Brian A; Mukherjee, Siddhartha; Sklar, Larry A; Kotz, Joanne D; Clish, Clary B; Sadreyev, Ruslan I; Clemons, Paul A; Janzer, Andreas; Schreiber, Stuart L; Scadden, David T.

Cell ; 167(1): 171-186.e15, 2016 Sep 22.

Article in English | MEDLINE | ID: mdl-27641501

2.

Health Consequences of Thymus Removal in Adults.

Kooshesh, Kameron A; Foy, Brody H; Sykes, David B; Gustafsson, Karin; Scadden, David T.

N Engl J Med ; 389(5): 406-417, 2023 Aug 03.

Article in English | MEDLINE | ID: mdl-37530823

3.

Image-seq: spatially resolved single-cell sequencing guided by in situ and in vivo imaging.

Haase, Christa; Gustafsson, Karin; Mei, Shenglin; Yeh, Shu-Chi; Richter, Dmitry; Milosevic, Jelena; Turcotte, Raphaël; Kharchenko, Peter V; Sykes, David B; Scadden, David T; Lin, Charles P.

Nat Methods ; 19(12): 1622-1633, 2022 12.

Article in English | MEDLINE | ID: mdl-36424441

4.

Limited plasticity of monocyte fate and function associated with epigenetic scripting at the level of progenitors.

Rhee, Catherine; Scadden, Elizabeth W; Wong, Lai Ping; Schiroli, Giulia; Mazzola, Michael C; Chea, Phillip L; Kato, Hiroki; Hoyer, Friedrich F; Mistry, Meeta; Lee, Bum-Kyu; Kim, Jonghwan; Nahrendorf, Matthias; Mansour, Michael K; Sykes, David B; Sadreyev, Ruslan I; Scadden, David T.

Blood ; 142(7): 658-674, 2023 08 17.

Article in English | MEDLINE | ID: mdl-37267513

5.

Disruption of dNTP homeostasis by ribonucleotide reductase hyperactivation overcomes AML differentiation blockade.

Wang, Hanying; He, Xin; Zhang, Lei; Dong, Haojie; Huang, Feiteng; Xian, Jie; Li, Min; Chen, Wei; Lu, Xiyuan; Pathak, Khyatiben V; Huang, Wenfeng; Li, Zheng; Zhang, Lianjun; Nguyen, Le Xuan Truong; Yang, Lu; Feng, Lifeng; Gordon, David J; Zhang, Jing; Pirrotte, Patrick; Chen, Chun-Wei; Salhotra, Amandeep; Kuo, Ya-Huei; Horne, David; Marcucci, Guido; Sykes, David B; Tiziani, Stefano; Jin, Hongchuan; Wang, Xian; Li, Ling.

Blood ; 139(26): 3752-3770, 2022 06 30.

Article in English | MEDLINE | ID: mdl-35439288

6.

TLR Signaling Rescues Fungicidal Activity in Syk-Deficient Neutrophils.

Viens, Adam L; Timmer, Kyle D; Alexander, Natalie J; Barghout, Rana; Milosevic, Jelena; Hopke, Alex; Atallah, Natalie J; Scherer, Allison K; Sykes, David B; Irimia, Daniel; Mansour, Michael K.

J Immunol ; 208(7): 1664-1674, 2022 04 01.

Article in English | MEDLINE | ID: mdl-35277418

7.

The TEMPI syndrome.

Sykes, David B; O'Connell, Casey; Schroyens, Wilfried.

Blood ; 135(15): 1199-1203, 2020 04 09.

Article in English | MEDLINE | ID: mdl-32108223

8.

Aldehyde dehydrogenase 3a2 protects AML cells from oxidative death and the synthetic lethality of ferroptosis inducers.

Yusuf, Rushdia Zareen; Saez, Borja; Sharda, Azeem; van Gastel, Nick; Yu, Vionnie W C; Baryawno, Ninib; Scadden, Elizabeth W; Acharya, Sanket; Chattophadhyay, Shrikanta; Huang, Cherrie; Viswanathan, Vasanthi; S'aulis, Dana; Cobert, Julien; Sykes, David B; Keibler, Mark A; Das, Sudeshna; Hutchinson, John N; Churchill, Michael; Mukherjee, Siddhartha; Lee, Dongjun; Mercier, Francois; Doench, John; Bullinger, Lars; Logan, David J; Schreiber, Stuart; Stephanopoulos, Gregory; Rizzo, William B; Scadden, David T.

Blood ; 136(11): 1303-1316, 2020 09 10.

Article in English | MEDLINE | ID: mdl-32458004

9.

Case 34-2023: A 49-Year-Old Woman with Loss of Consciousness and Thrombocytopenia.

Zachrison, Kori S; Kamalian, Shahmir; Sykes, David B; Brunker, Patricia A R.

N Engl J Med ; 389(19): 1804-1811, 2023 Nov 09.

Article in English | MEDLINE | ID: mdl-37937781

10.

Severe autoimmune hemolytic anemia following receipt of SARS-CoV-2 mRNA vaccine.

Gadi, Sanjay R V; Brunker, Patricia A R; Al-Samkari, Hanny; Sykes, David B; Saff, Rebecca R; Lo, Janet; Bendapudi, Pavan; Leaf, David E; Leaf, Rebecca Karp.

Transfusion ; 61(11): 3267-3271, 2021 11.

Article in English | MEDLINE | ID: mdl-34549821

11.

An unappreciated role for neutrophil-DC hybrids in immunity to invasive fungal infections.

Fites, J Scott; Gui, Michael; Kernien, John F; Negoro, Paige; Dagher, Zeina; Sykes, David B; Nett, Jeniel E; Mansour, Michael K; Klein, Bruce S.

PLoS Pathog ; 14(5): e1007073, 2018 05.

Article in English | MEDLINE | ID: mdl-29782541

12.

Case 10-2020: An 83-Year-Old Man with Pancytopenia and Acute Renal Failure.

Sykes, David B; Zhang, Eric W; Karp Leaf, Rebecca S; Nardi, Valentina; Turbett, Sarah E.

N Engl J Med ; 382(13): 1258-1266, 2020 03 26.

Article in English | MEDLINE | ID: mdl-32212524

13.

Host defense against fungal pathogens: Adaptable neutrophil responses and the promise of therapeutic opportunities?

Scherer, Allison K; Hopke, Alex; Sykes, David B; Irimia, Daniel; Mansour, Michael K.

PLoS Pathog ; 17(7): e1009691, 2021 07.

Article in English | MEDLINE | ID: mdl-34324592

14.

The Successful Use of Apixaban in Dialysis Patients with Calciphylaxis Who Require Anticoagulation: A Retrospective Analysis.

Garza-Mayers, Anna C; Shah, Radhika; Sykes, David B; Nigwekar, Sagar U; Kroshinsky, Daniela.

Am J Nephrol ; 48(3): 168-171, 2018.

Article in English | MEDLINE | ID: mdl-30176675

15.

Complete Responses in the TEMPI Syndrome after Treatment with Daratumumab.

Sykes, David B; Schroyens, Wilfried.

N Engl J Med ; 378(23): 2240-2242, 2018 06 07.

Article in English | MEDLINE | ID: mdl-29874534

16.

A case of antisynthetase syndrome with thrombotic thrombocytopenic purpura.

Goreshnik, Ashley; Serling-Boyd, Naomi; Theodore, Miranda; Champion, Samantha; Stemmer-Rachamimov, Anat; Sykes, David B.

Rheumatology (Oxford) ; 60(4): e143-e145, 2021 04 06.

Article in English | MEDLINE | ID: mdl-33221867

17.

The Art of Oncology: COVID-19 Era.

Reynolds, Kerry L; Klempner, Samuel J; Parikh, Aparna; Hochberg, Ephraim P; Michaelson, M Dror; Mooradian, Meghan J; Lee, Richard J; Soumerai, Tara E; Hobbs, Gabriela; Piotrowska, Zofia; Sykes, David B; Farago, Anna F; Bardia, Aditya; Rosovsky, Rachel P; Ryan, David P.

Oncologist ; 25(11): 997-1000g, 2020 11.

Article in English | MEDLINE | ID: mdl-32697887

18.

Case 40-2017. A 32-Year-Old Woman with Headache, Abdominal Pain, Anemia, and Thrombocytopenia.

Sykes, David B; Rosovsky, Rachel P; Singhal, Aneesh B; Gonzalez, R Gilberto; Moy, Andrea P.

N Engl J Med ; 377(26): 2581-2590, 2017 12 28.

Article in English | MEDLINE | ID: mdl-29281575

19.

Bone marrow findings of the newly described TEMPI syndrome: when erythrocytosis and plasma cell dyscrasia coexist.

Rosado, Flavia G; Oliveira, Jennifer L; Sohani, Aliya R; Schroyens, Wilfried; Sykes, David B; Kenderian, Saad S; Lacy, Martha Q; Kyle, Robert A; Hoyer, James D.

Mod Pathol ; 28(3): 367-72, 2015 Mar.

Article in English | MEDLINE | ID: mdl-25216227

20.

Hormones and the bone marrow: panhypopituitarism and pancytopenia in a man with a pituitary adenoma.

Lang, Dianna; Mead, Jennifer S; Sykes, David B.

J Gen Intern Med ; 30(5): 692-6, 2015 May.

Article in English | MEDLINE | ID: mdl-25583570

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