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1.

PK-M2 Makes Cells Sweeter on HIF1.

Tennant, Daniel A.

Cell ; 145(5): 647-9, 2011 May 27.

Article in English | MEDLINE | ID: mdl-21620132

2.

Interplay of p53 and XIAP protein dynamics orchestrates cell fate in response to chemotherapy.

Abukwaik, Roba; Vera-Siguenza, Elias; Tennant, Daniel A; Spill, Fabian.

J Theor Biol ; 572: 111562, 2023 09 07.

Article in English | MEDLINE | ID: mdl-37348784

3.

1,25-Dihydroxyvitamin D3 suppresses CD4⁺ T-cell effector functionality by inhibition of glycolysis.

Bishop, Emma L; Gudgeon, Nancy H; Mackie, Gillian M; Chauss, Daniel; Roberts, Jennie; Tennant, Daniel A; Maslowski, Kendle M; Afzali, Behdad; Hewison, Martin; Dimeloe, Sarah.

Immunology ; 166(3): 299-309, 2022 07.

Article in English | MEDLINE | ID: mdl-35322416

4.

Succinate dehydrogenase deficiency in a chromaffin cell model retains metabolic fitness through the maintenance of mitochondrial NADH oxidoreductase function.

Klucková, Katarína; Thakker, Alpesh; Vettore, Lisa; Escribano-Gonzalez, Cristina; Hindshaw, Rebecca L; Tearle, Jacqueline L E; Goncalves, Judith; Kaul, Baksho; Lavery, Gareth G; Favier, Judith; Tennant, Daniel A.

FASEB J ; 34(1): 303-315, 2020 01.

Article in English | MEDLINE | ID: mdl-31914648

5.

Proline metabolism and redox; maintaining a balance in health and disease.

Vettore, Lisa A; Westbrook, Rebecca L; Tennant, Daniel A.

Amino Acids ; 53(12): 1779-1788, 2021 Dec.

Article in English | MEDLINE | ID: mdl-34291343

6.

New aspects of amino acid metabolism in cancer.

Vettore, Lisa; Westbrook, Rebecca L; Tennant, Daniel A.

Br J Cancer ; 122(2): 150-156, 2020 01.

Article in English | MEDLINE | ID: mdl-31819187

7.

Metabolic implications of hypoxia and pseudohypoxia in pheochromocytoma and paraganglioma.

Kluckova, Katarina; Tennant, Daniel A.

Cell Tissue Res ; 372(2): 367-378, 2018 05.

Article in English | MEDLINE | ID: mdl-29450727

8.

Metabolic differences between cold stored and machine perfused porcine kidneys: A ¹H NMR based study.

Nath, Jay; Smith, Tom B; Patel, Kamlesh; Ebbs, Sam R; Hollis, Alex; Tennant, Daniel A; Ludwig, Christian; Ready, Andrew R.

Cryobiology ; 74: 115-120, 2017 02.

Article in English | MEDLINE | ID: mdl-27919740

9.

Combined Analysis of NMR and MS Spectra (CANMS).

Chong, Mei; Jayaraman, Anusha; Marin, Silvia; Selivanov, Vitaly; de Atauri Carulla, Pedro R; Tennant, Daniel A; Cascante, Marta; Günther, Ulrich L; Ludwig, Christian.

Angew Chem Int Ed Engl ; 56(15): 4140-4144, 2017 04 03.

Article in English | MEDLINE | ID: mdl-28272839

10.

Isocitrate dehydrogenase (IDH), succinate dehydrogenase (SDH), fumarate hydratase (FH): three players for one phenotype in cancer?

Laurenti, Giulio; Tennant, Daniel A.

Biochem Soc Trans ; 44(4): 1111-6, 2016 08 15.

Article in English | MEDLINE | ID: mdl-27528759

11.

Probing Cancer Cell Metabolism Using NMR Spectroscopy.

Hollinshead, Kate E R; Williams, Debbie S; Tennant, Daniel A; Ludwig, Christian.

Adv Exp Med Biol ; 899: 89-111, 2016.

Article in English | MEDLINE | ID: mdl-27325263

12.

Hypoxia inducible factors in liver disease and hepatocellular carcinoma: current understanding and future directions.

Wilson, Garrick K; Tennant, Daniel A; McKeating, Jane A.

J Hepatol ; 61(6): 1397-406, 2014 Dec.

Article in English | MEDLINE | ID: mdl-25157983

13.

TNF-α signals through ITK-Akt-mTOR to drive CD4⁺ T cell metabolic reprogramming, which is dysregulated in rheumatoid arthritis.

Bishop, Emma L; Gudgeon, Nancy; Fulton-Ward, Taylor; Stavrou, Victoria; Roberts, Jennie; Boufersaoui, Adam; Tennant, Daniel A; Hewison, Martin; Raza, Karim; Dimeloe, Sarah.

Sci Signal ; 17(833): eadg5678, 2024 Apr 23.

Article in English | MEDLINE | ID: mdl-38652761

14.

Residual Complex I activity and amphidirectional Complex II operation support glutamate catabolism through mtSLP in anoxia.

Ravasz, Dora; Bui, David; Nazarian, Sara; Pallag, Gergely; Karnok, Noemi; Roberts, Jennie; Marzullo, Bryan P; Tennant, Daniel A; Greenwood, Bennett; Kitayev, Alex; Hill, Collin; Komlódi, Timea; Doerrier, Carolina; Cunatova, Kristyna; Fernandez-Vizarra, Erika; Gnaiger, Erich; Kiebish, Michael A; Raska, Alexandra; Kolev, Krasimir; Czumbel, Bence; Narain, Niven R; Seyfried, Thomas N; Chinopoulos, Christos.

Sci Rep ; 14(1): 1729, 2024 01 19.

Article in English | MEDLINE | ID: mdl-38242919

15.

LDHB contributes to the regulation of lactate levels and basal insulin secretion in human pancreatic ß cells.

Cuozzo, Federica; Viloria, Katrina; Shilleh, Ali H; Nasteska, Daniela; Frazer-Morris, Charlotte; Tong, Jason; Jiao, Zicong; Boufersaoui, Adam; Marzullo, Bryan; Rosoff, Daniel B; Smith, Hannah R; Bonner, Caroline; Kerr-Conte, Julie; Pattou, Francois; Nano, Rita; Piemonti, Lorenzo; Johnson, Paul R V; Spiers, Rebecca; Roberts, Jennie; Lavery, Gareth G; Clark, Anne; Ceresa, Carlo D L; Ray, David W; Hodson, Leanne; Davies, Amy P; Rutter, Guy A; Oshima, Masaya; Scharfmann, Raphaël; Merrins, Matthew J; Akerman, Ildem; Tennant, Daniel A; Ludwig, Christian; Hodson, David J.

Cell Rep ; 43(4): 114047, 2024 Apr 23.

Article in English | MEDLINE | ID: mdl-38607916

16.

VHL-deficiency leads to reductive stress in renal cells.

Vellama, Hans; Eskla, Kattri-Liis; Eichelmann, Hillar; Hüva, Andria; Tennant, Daniel A; Thakker, Alpesh; Roberts, Jennie; Jagomäe, Toomas; Porosk, Rando; Laisk, Agu; Oja, Vello; Rämma, Heikko; Volke, Vallo; Vasar, Eero; Luuk, Hendrik.

Free Radic Biol Med ; 208: 1-12, 2023 11 01.

Article in English | MEDLINE | ID: mdl-37506952

17.

The glucocorticoid dexamethasone inhibits HIF-1α stabilization and metabolic reprogramming in lipopolysaccharide-stimulated primary macrophages.

Clayton, Sally A; Lockwood, Chloe; O'Neil, John D; Daley, Kalbinder K; Hain, Sofia; Abdelmottaleb, Dina; Bolimowska, Oliwia O; Tennant, Daniel A; Clark, Andrew R.

Discov Immunol ; 2(1): kyad027, 2023.

Article in English | MEDLINE | ID: mdl-38567068

18.

Uptake of long-chain fatty acids from the bone marrow suppresses CD8+ T-cell metabolism and function in multiple myeloma.

Gudgeon, Nancy; Giles, Hannah; Bishop, Emma L; Fulton-Ward, Taylor; Escribano-Gonzalez, Cristina; Munford, Haydn; James-Bott, Anna; Foster, Kane; Karim, Farheen; Jayawardana, Dedunu; Mahmood, Ansar; Cribbs, Adam P; Tennant, Daniel A; Basu, Supratik; Pratt, Guy; Dimeloe, Sarah.

Blood Adv ; 7(20): 6035-6047, 2023 10 24.

Article in English | MEDLINE | ID: mdl-37276076

19.

NAD depletion mediates cytotoxicity in human neurons with autophagy deficiency.

Sun, Congxin; Seranova, Elena; Cohen, Malkiel A; Chipara, Miruna; Roberts, Jennie; Astuti, Dewi; Palhegyi, Adina M; Acharjee, Animesh; Sedlackova, Lucia; Kataura, Tetsushi; Otten, Elsje G; Panda, Prashanta K; Lara-Reyna, Samuel; Korsgen, Miriam E; Kauffman, Kevin J; Huerta-Uribe, Alejandro; Zatyka, Malgorzata; Silva, Luiz F S E; Torresi, Jorge; Zhang, Shupei; Hughes, Georgina W; Ward, Carl; Kuechler, Erich R; Cartwright, David; Trushin, Sergey; Trushina, Eugenia; Sahay, Gaurav; Buganim, Yosef; Lavery, Gareth G; Gsponer, Joerg; Anderson, Daniel G; Frickel, Eva-Maria; Rosenstock, Tatiana R; Barrett, Timothy; Maddocks, Oliver D K; Tennant, Daniel A; Wang, Haoyi; Jaenisch, Rudolf; Korolchuk, Viktor I; Sarkar, Sovan.

Cell Rep ; 42(5): 112372, 2023 05 30.

Article in English | MEDLINE | ID: mdl-37086404

20.

Succinate uptake by T cells suppresses their effector function via inhibition of mitochondrial glucose oxidation.

Gudgeon, Nancy; Munford, Haydn; Bishop, Emma L; Hill, James; Fulton-Ward, Taylor; Bending, David; Roberts, Jennie; Tennant, Daniel A; Dimeloe, Sarah.

Cell Rep ; 40(7): 111193, 2022 08 16.

Article in English | MEDLINE | ID: mdl-35977513

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