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1.
Discovery of DS-3801b, a non-macrolide GPR38 agonist with N-methylanilide structure.
Bioorg Med Chem Lett
; 59: 128554, 2022 03 01.
Article
in English
| MEDLINE | ID: mdl-35051575
2.
Optimization of 3-aryl-3-ethoxypropanoic acids and discovery of the potent GPR40 agonist DS-1558.
Bioorg Med Chem
; 23(17): 5546-65, 2015 Sep 01.
Article
in English
| MEDLINE | ID: mdl-26234904
3.
Discovery of 3-aryl-3-ethoxypropanoic acids as orally active GPR40 agonists.
Bioorg Med Chem Lett
; 24(13): 2949-53, 2014 Jul 01.
Article
in English
| MEDLINE | ID: mdl-24835985
4.
A chemically programmed antibody is a long-lasting and potent inhibitor of influenza neuraminidase.
Chembiochem
; 13(15): 2191-5, 2012 Oct 15.
Article
in English
| MEDLINE | ID: mdl-22965667
5.
Organocatalytic amidation and esterification of aldehydes with activating reagents by a cross-coupling strategy.
Angew Chem Int Ed Engl
; 51(50): 12538-41, 2012 Dec 07.
Article
in English
| MEDLINE | ID: mdl-23135813
6.
Development of an efficient therapeutic agent for Alzheimer's disease: design and synthesis of dual inhibitors of acetylcholinesterase and serotonin transporter.
Chem Pharm Bull (Tokyo)
; 58(3): 273-87, 2010 Mar.
Article
in English
| MEDLINE | ID: mdl-20190429
7.
Rapid, stable, chemoselective labeling of thiols with Julia-Kocienski-like reagents: a serum-stable alternative to maleimide-based protein conjugation.
Angew Chem Int Ed Engl
; 52(48): 12592-6, 2013 Nov 25.
Article
in English
| MEDLINE | ID: mdl-24123851
8.
Discovery of DS-1558: A Potent and Orally Bioavailable GPR40 Agonist.
ACS Med Chem Lett
; 6(3): 266-70, 2015 Mar 12.
Article
in English
| MEDLINE | ID: mdl-25815144
9.
Total synthesis of (+)-benzastatin E via diastereoselective Grignard addition to 2-acylindoline.
Org Lett
; 5(3): 269-71, 2003 Feb 06.
Article
in English
| MEDLINE | ID: mdl-12556169
10.
Design and synthesis of dual inhibitors of acetylcholinesterase and serotonin transporter targeting potential agents for Alzheimer's disease.
Org Lett
; 4(20): 3359-62, 2002 Oct 03.
Article
in English
| MEDLINE | ID: mdl-12323018
11.
Potentiation of insulin secretion and improvement of glucose intolerance by combining a novel G protein-coupled receptor 40 agonist DS-1558 with glucagon-like peptide-1 receptor agonists.
Eur J Pharmacol
; 737: 194-201, 2014 Aug 15.
Article
in English
| MEDLINE | ID: mdl-24858371
12.
Potent and Orally Bioavailable GPR142 Agonists as Novel Insulin Secretagogues for the Treatment of Type 2 Diabetes.
ACS Med Chem Lett
; 4(8): 790-4, 2013 Aug 08.
Article
in English
| MEDLINE | ID: mdl-24900747
13.
Stereospecific construction of contiguous quaternary and tertiary stereocenters by rearrangement from indoline-2-methanol to 2,2,3-trisubstituted tetrahydroquinoline: application to an efficient total synthesis of natural virantmycin.
Angew Chem Int Ed Engl
; 42(22): 2540-3, 2003 Jun 06.
Article
in English
| MEDLINE | ID: mdl-12800182
14.
Transition-metal-catalyzed sequential cross-coupling of bis(iodozincio)methane and -ethane with two different organic halides.
Chemistry
; 12(3): 721-6, 2006 Jan 11.
Article
in English
| MEDLINE | ID: mdl-16224768
15.
Design, synthesis and structure-activity relationships of dual inhibitors of acetylcholinesterase and serotonin transporter as potential agents for Alzheimer's disease.
Bioorg Med Chem
; 11(9): 1935-55, 2003 May 01.
Article
in English
| MEDLINE | ID: mdl-12670645
16.
Pharmacological characterization of RS-1259, an orally active dual inhibitor of acetylcholinesterase and serotonin transporter, in rodents: possible treatment of Alzheimer's disease.
J Pharmacol Sci
; 93(1): 95-105, 2003 Sep.
Article
in English
| MEDLINE | ID: mdl-14501158
17.
A conformational restriction approach to the development of dual inhibitors of acetylcholinesterase and serotonin transporter as potential agents for Alzheimer's disease.
Bioorg Med Chem
; 11(20): 4389-415, 2003 Oct 01.
Article
in English
| MEDLINE | ID: mdl-13129577
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