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1.
Brain Res ; 538(1): 152-6, 1991 Jan 04.
Article in English | MEDLINE | ID: mdl-2018927

ABSTRACT

Physiological stimuli which increase postural extensor tone also increase excitability of the crossed extension reflex (CER). We report here that such stimuli increase excitability of the CER recorded from rectus femoris (RF) more than that of vastus medialis (VM). The difference might reflect an important role of the biarticular actions of RF, which is also a weak hip flexor, in stabilizing the hip as well as extending the knee during maintenance of posture.


Subject(s)
Muscles/innervation , Posture , Reflex , Sciatic Nerve/physiology , Tibial Nerve/physiology , Animals , Cats , Decerebrate State , Electric Stimulation , Hindlimb/innervation , Isometric Contraction , Joints/physiology
3.
Clin Transplant ; 15 Suppl 6: 11-5, 2001.
Article in English | MEDLINE | ID: mdl-11903380

ABSTRACT

This study was undertaken to examine the presentation and outcomes relative to solid organ donation in patients with fatal cerebral gunshot wounds at a level I trauma center over a 7-year period. A retrospective chart review of patients with such wounds over the years 1993-99 was completed. Eighty (80) patients were considered potential solid organ donors. Of these, 28 (35%) became organ donors, yielding 97 transplantable organs. Ninety-six percent presented with a GCS of less than 6. Mean SBP on presentation was 130, ranging from 48 to 225. Median time from presentation to death was 18 hours. Intravenous fluids given over the first 6 hours averaged 4.3 liters. Pressors were required in 68% of cases, blood products in 34%. Consent rate for donation was 32% when requested by a physician and 59% when requested by an organ procurement organization (OPO) co-ordinator. No request was made in 15 cases. Patients with fatal cerebral gunshot wounds, but with solid organ donor potential, have a characteristic presentation. Those with hemodynamic stability and those whose hypotension responds promptly to treatment can be expected to have a donor potential despite their devastating brain injury. Minimal time and resources are required to support such patients. Additional organs may have been obtained if the request for donation was consistently separated from the families' notification of brain death, and if the request was initiated by an OPO coordinator rather than a physician. Further, all patients admitted with cerebral gunshot wounds and poor neurologic function should have local OPO referral, potential survival notwithstanding.


Subject(s)
Brain Injuries/mortality , Tissue Donors/statistics & numerical data , Tissue and Organ Procurement/methods , Wounds, Gunshot/mortality , Adolescent , Adult , Aged , Child , Female , Glasgow Coma Scale , Humans , Male , Middle Aged , Retrospective Studies , Tissue and Organ Procurement/statistics & numerical data , Trauma Centers , Treatment Outcome
4.
Ann Surg ; 227(5): 618-24; discussion 624-6, 1998 May.
Article in English | MEDLINE | ID: mdl-9605653

ABSTRACT

OBJECTIVE: The success of elective minimally invasive surgery suggested that this concept could be adapted to the intensive care unit. We hypothesized that minimally invasive surgery could be done safely and cost-effectively at the bedside in critically injured patients. SUMMARY BACKGROUND DATA: This case series, conducted between October 1991 and June 1997 at a Level I trauma center, examined bedside dilatational tracheostomy (BDT), percutaneous endoscopic gastrostomy (PEG), and inferior vena cava (IVC) filter placement. All procedures had been performed in the operating room (OR) before initiation of this study. METHODS: All BDTs and PEGs were performed with intravenous general anesthesia (fentanyl, diazepam, and pancuronium) administered by the surgical team. IVC filters were placed using local anesthesia and conscious sedation. BDTs were done using a Ciaglia set, PEGs were done using a 20 Fr Flexiflow Inverta-PEG kit, and IVC filters were placed percutaneously under ultrasound guidance. Cost difference (delta cost) was defined as the difference in hospital cost and physician charges incurred in the OR as compared to the bedside. RESULTS: Of 16,417 trauma admissions, 379 patients (2%) underwent 472 minimally invasive procedures (272 BDTs, 129 PEGs, 71 IVC filters). There were four major complications (0.8%). Two patients had loss of airway requiring reintubation. Two patients had an intraperitoneal leak from the gastrostomy requiring operative repair. No patient had a major complication after IVC filter placement. Total delta cost was $611,994. When examined independently, the cost was $324,224 for BDT, $164,088 for PEG, and $123,682 for IVC filter. OR use was reduced by 506 hours. CONCLUSIONS: These bedside procedures have minimal complications, eliminate the risk associated with patient transport, reduce cost, improve OR utilization, and should be considered for routine use in the general surgery population.


Subject(s)
Critical Illness , Elective Surgical Procedures , Minimally Invasive Surgical Procedures , Wounds and Injuries/surgery , Adult , Cost-Benefit Analysis , Elective Surgical Procedures/economics , Gastrostomy/methods , Hospital Charges , Hospital Costs , Humans , Minimally Invasive Surgical Procedures/economics , Point-of-Care Systems , Tracheostomy/methods , United States , Vena Cava Filters
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