Search details
1.
Regulation of ferroptotic cancer cell death by GPX4.
Cell
; 156(1-2): 317-331, 2014 Jan 16.
Article
in English
| MEDLINE | ID: mdl-24439385
2.
Drug-tolerant persister cancer cells are vulnerable to GPX4 inhibition.
Nature
; 551(7679): 247-250, 2017 11 09.
Article
in English
| MEDLINE | ID: mdl-29088702
3.
Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway.
Nature
; 547(7664): 453-457, 2017 07 27.
Article
in English
| MEDLINE | ID: mdl-28678785
4.
Selective covalent targeting of GPX4 using masked nitrile-oxide electrophiles.
Nat Chem Biol
; 16(5): 497-506, 2020 05.
Article
in English
| MEDLINE | ID: mdl-32231343
5.
Structure-activity relationships of GPX4 inhibitor warheads.
Bioorg Med Chem Lett
; 30(23): 127538, 2020 12 01.
Article
in English
| MEDLINE | ID: mdl-32920142
6.
Diacylfuroxans Are Masked Nitrile Oxides That Inhibit GPX4 Covalently.
J Am Chem Soc
; 141(51): 20407-20415, 2019 12 26.
Article
in English
| MEDLINE | ID: mdl-31841309
7.
Validation of ferroptosis in canine cancer cells to enable comparative oncology and translational medicine.
bioRxiv
; 2024 Apr 30.
Article
in English
| MEDLINE | ID: mdl-38746359
8.
ROS Induction Targets Persister Cancer Cells with Low Metabolic Activity in NRAS-Mutated Melanoma.
Cancer Res
; 83(7): 1128-1146, 2023 04 04.
Article
in English
| MEDLINE | ID: mdl-36946761
9.
Crystal structures of the selenoprotein glutathione peroxidase 4 in its apo form and in complex with the covalently bound inhibitor ML162.
Acta Crystallogr D Struct Biol
; 77(Pt 2): 237-248, 2021 Feb 01.
Article
in English
| MEDLINE | ID: mdl-33559612
10.
A GPX4-dependent cancer cell state underlies the clear-cell morphology and confers sensitivity to ferroptosis.
Nat Commun
; 10(1): 1617, 2019 04 08.
Article
in English
| MEDLINE | ID: mdl-30962421
11.
Inhibition of Zinc-Dependent Histone Deacetylases with a Chemically Triggered Electrophile.
ACS Chem Biol
; 11(7): 1844-51, 2016 07 15.
Article
in English
| MEDLINE | ID: mdl-27064299
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