Complexity and Cognitive Engagement in the Rorschach Task: An fMRI Study.

Recently, an eye-tracking study found that Complexity and other R-PAS variables located in the Engagement and Cognitive Processing domain correlated with a proxy marker for cognitive effort and engagement. The goal of the current study was to test the robustness and validity of those eye-tracking findings by inspecting fMRI data. We hypothesized that the greater the level of engagement and cognitive effort put in place by a Rorschach test-taker, the greater the engagement of his/her cortical areas reflecting ongoing top-down attentional processes should be. We re-analyzed archival fMRI data from 26 healthy participants exposed to the Rorschach inkblots with the instruction to think of what they might be. The association of various Engagement and Cognitive Processing R-PAS scores to increased BOLD signals in the Dorsal Attention Network of the brain was examined. As expected, Complexity showed the strongest effect size across all R-PAS variables under investigation (d = 0.43), followed by Synthesis (d = 0.32) and Human Movement (d = 0.21). Noteworthy, the correlation between the effect sizes found in the current fMRI study and those found in the previously published eye-tracking study consists of an impressive r = .80.

Introducing the concept of neurobiological foundation of Rorschach responses using the example of Oral Dependent Language.

We introduce the concept of "neurobiological foundation" of Rorschach interpretations as an extension of the concept of behavioral representation as a foundation for interpretation of R-PAS variables. Here, we propose that if there is a parallelism between the mental, verbal and perceptual behaviors occurring within the microcosm of the Rorschach task and those occurring in the external environment [behavioral foundation], then the same brain regions engaged by the test-taker when producing of a given code, should be engaged also when reproducing, in the external environment, the same psychological processes underlying that specific Rorschach code [neurobiological foundation]. To investigate this concept, we used archival, fMRI data and tested whether producing Oral Dependency Language (ODL) responses would associate with increased activation in brain regions associated with dependency-related, psychological processes. Results from a sample of 21 non-clinical volunteers partially confirmed our hypothesis, providing some support to the neurobiological foundation of the ODL code.

Affective Neuroscience Personality Scale (ANPS) and clinical implications: A systematic review.

BACKGROUND: Affective neuroscience (AN) theory assumes the existence of seven basic emotional systems (i.e., SEEKING, ANGER, FEAR, CARE, LUST, SADNESS, PLAY) that are common to all mammals and evolutionarily determined to be tools for survival and, in general, for fitness. Based on the AN approach, the Affective Neuroscience Personality Scales (ANPS) questionnaire was developed to examine individual differences in the defined basic emotional systems. The current systematic review aims to examine the use of ANPS in clinical contexts attempting to define those behavioral elements associated with underlying stable personality traits. METHODS: The systematic review was conducted following the PRISMA statements. PubMed and PsycInfo were used for research literature from March 2003 to November 2021. RESULTS: Forty-four studies including ANPS were identified from 1763 studies reviewed. Sixteen studies met the inclusion criteria. LIMITATIONS: The review comprised some papers with incomplete psychological assessments (e.g., lack of other measures in addition to the ANPS) and missing information (e.g., on the [sub]samples), which may affect the generalizability of findings. CONCLUSION: Specific endophenotypes and/or patterns of emotional/motivational systems were found for several mental disorders. Specifically, endophenotypes emerged for the Depressive and Autism Spectrum Disorders, Borderline and Avoidant Personality Disorders, type I and II Bipolar Disorders, and the Obsessive-Compulsive Disorder. The endophenotypes can provide useful reflective elements for both psychodiagnosis and intervention. Overall, the current study may represent an attempt to contribute to the understanding of the basic emotional systems involved in the psychopathological manifestations identified by AN.

Markers of emotion regulation processes: A neuroimaging and behavioral study of reappraising abilities.

Emotion regulation (ER) is a core element for individual well-being, and dysregulated emotional states are prominent in several mental disorders. Moreover, dispositional use of adaptive ER strategies, such as cognitive reappraisal, is usually associated to better psychological outcomes and less emotional problems. Thus, identifying markers of emotion dysregulation could serve as a key point for developing treatments against risks of psychopathological outcomes. Neuroimaging techniques could represent a useful tool within these aims, focusing on neurobiological markers of psychopathological illness. Given the well known gender differences in using ER strategies, we examined behavioral and neuroimaging patterns associated with dispositional use of reappraisal among a non-clinical female sample. We found that the individual predisposition to use cognitive reappraisal as an emotion regulation strategy was associated with decreased levels of dysregulation. From a neurobiological perspective, difficulties in using reappraisal were associated with decreased resting-state functional connectivity (rs-FC) between the Middle Temporal Gyrus and occipito-parietal regions. Moreover, rs-FC between prefrontal and occipito-parietal brain regions was negatively associated with emotion dysregulation levels. Microstructural anomalies across white matter tracts connecting temporal, parietal, and occipital brain regions were associated to difficulties in using reappraisal. Our findings suggest that specific behavioral and neurobiological substrates are linked to reappraising abilities. Furthermore, the ability to implement adaptive ER strategies could serve as protective factor against developing emotion dysregulation.

White matter and schizophrenia: A meta-analysis of voxel-based morphometry and diffusion tensor imaging studies.

Voxel-based morphometry (VBM) and diffusion tensor imaging (DTI) are the most implemented methodologies to detect alterations of both gray and white matter (WM). However, the role of WM in mental disorders is still not well defined. We aimed at clarifying the role of WM disruption in schizophrenia and at identifying the most frequently involved brain networks. A systematic literature search was conducted to identify VBM and DTI studies focusing on WM alterations in patients with schizophrenia compared to control subjects. We selected studies reporting the coordinates of WM reductions and we performed the anatomical likelihood estimation (ALE). Moreover, we labeled the WM bundles with an anatomical atlas and compared VBM and DTI ALE-scores of each significant WM tract. A total of 59 studies were eligible for the meta-analysis. WM alterations were reported in 31 and 34 foci with VBM and DTI methods, respectively. The most occurred WM bundles in both VBM and DTI studies and largely involved in schizophrenia were long projection fibers, callosal and commissural fibers, part of motor descending fibers, and fronto-temporal-limbic pathways. The meta-analysis showed a widespread WM disruption in schizophrenia involving specific cerebral circuits instead of well-defined regions.