Search | VHL Search Portal

1.

Pkd2 Deficiency in Embryonic Aqp2 + Progenitor Cells Is Sufficient to Cause Severe Polycystic Kidney Disease.

Tsilosani, Akaki; Gao, Chao; Chen, Enuo; Lightle, Andrea R; Shehzad, Sana; Sharma, Madhulika; Tran, Pamela V; Bates, Carlton M; Wallace, Darren P; Zhang, Wenzheng.

J Am Soc Nephrol ; 35(4): 398-409, 2024 Apr 01.

Article in English | MEDLINE | ID: mdl-38254271

2.

Metabolomic profiling to identify early urinary biomarkers and metabolic pathway alterations in autosomal dominant polycystic kidney disease.

Houske, Eden A; Glimm, Matthew G; Bergstrom, Annika R; Slipher, Sally K; Welhaven, Hope D; Greenwood, Mark C; Linse, Greta M; June, Ronald K; Yu, Alan S L; Wallace, Darren P; Hahn, Alyssa K.

Am J Physiol Renal Physiol ; 324(6): F590-F602, 2023 06 01.

Article in English | MEDLINE | ID: mdl-37141147

3.

Accuracy and processing time of kidney volume measurement methods in rodents polycystic kidney disease models: superiority of semiautomated kidney segmentation.

Doss, Mary Claire; Mullen, Sean; Roye, Ronald; Zhou, Juling; Chumley, Phillip; Mrug, Elias; Wallace, Darren P; Qian, Feng; Harris, Peter C; Yoder, Bradley K; Kim, Harrison; Mrug, Michal.

Am J Physiol Renal Physiol ; 324(4): F423-F430, 2023 04 01.

Article in English | MEDLINE | ID: mdl-36794756

4.

The lonidamine derivative H2-gamendazole reduces cyst formation in polycystic kidney disease.

Sundar, Shirin V; Zhou, Julie Xia; Magenheimer, Brenda S; Reif, Gail A; Wallace, Darren P; Georg, Gunda I; Jakkaraj, Sudhakar R; Tash, Joseph S; Yu, Alan S L; Li, Xiaogang; Calvet, James P.

Am J Physiol Renal Physiol ; 323(4): F492-F506, 2022 10 01.

Article in English | MEDLINE | ID: mdl-35979967

5.

Expression of active B-Raf proto-oncogene in kidney collecting ducts induces cyst formation in normal mice and accelerates cyst growth in mice with polycystic kidney disease.

Parnell, Stephen C; Raman, Archana; Zhang, Yan; Daniel, Emily A; Dai, Yuqiao; Khanna, Aditi; Reif, Gail A; Vivian, Jay L; Fields, Timothy A; Wallace, Darren P.

Kidney Int ; 102(5): 1103-1114, 2022 11.

Article in English | MEDLINE | ID: mdl-35760151

6.

Ttc21b deficiency attenuates autosomal dominant polycystic kidney disease in a kidney tubular- and maturation-dependent manner.

Wang, Wei; Silva, Luciane M; Wang, Henry H; Kavanaugh, Matthew A; Pottorf, Tana S; Allard, Bailey A; Jacobs, Damon T; Dong, Rouchen; Cornelius, Joseph T; Chaturvedi, Aakriti; Swenson-Fields, Katherine I; Fields, Timothy A; Pritchard, Michele T; Sharma, Madhulika; Slawson, Chad; Wallace, Darren P; Calvet, James P; Tran, Pamela V.

Kidney Int ; 102(3): 577-591, 2022 09.

Article in English | MEDLINE | ID: mdl-35644283

7.

Quinomycin A reduces cyst progression in polycystic kidney disease.

Radadiya, Priyanka S; Thornton, Mackenzie M; Daniel, Emily A; Idowu, Jessica Y; Wang, Wei; Magenheimer, Brenda; Subramaniam, Dharmalingam; Tran, Pamela V; Calvet, James P; Wallace, Darren P; Sharma, Madhulika.

FASEB J ; 35(5): e21533, 2021 05.

Article in English | MEDLINE | ID: mdl-33826787

8.

Epithelial Vasopressin Type-2 Receptors Regulate Myofibroblasts by a YAP-CCN2-Dependent Mechanism in Polycystic Kidney Disease.

Dwivedi, Nidhi; Tao, Shixin; Jamadar, Abeda; Sinha, Sonali; Howard, Christianna; Wallace, Darren P; Fields, Timothy A; Leask, Andrew; Calvet, James P; Rao, Reena.

J Am Soc Nephrol ; 31(8): 1697-1710, 2020 08.

Article in English | MEDLINE | ID: mdl-32554753

9.

Overexpression of TGF-ß1 induces renal fibrosis and accelerates the decline in kidney function in polycystic kidney disease.

Zhang, Yan; Dai, Yuqiao; Raman, Archana; Daniel, Emily; Metcalf, July; Reif, Gail; Pierucci-Alves, Fernando; Wallace, Darren P.

Am J Physiol Renal Physiol ; 319(6): F1135-F1148, 2020 12 01.

Article in English | MEDLINE | ID: mdl-33166182

10.

MCP-1 promotes detrimental cardiac physiology, pulmonary edema, and death in the cpk model of polycystic kidney disease.

Salah, Sally M; Meisenheimer, James D; Rao, Reena; Peda, Jacqueline D; Wallace, Darren P; Foster, Dawson; Li, Xiaogang; Li, Xiaoyan; Zhou, Xia; Vallejo, Julian A; Wacker, Michael J; Fields, Timothy A; Swenson-Fields, Katherine I.

Am J Physiol Renal Physiol ; 317(2): F343-F360, 2019 08 01.

Article in English | MEDLINE | ID: mdl-31091126

11.

Deficient transient receptor potential vanilloid type 4 function contributes to compromised [Ca²⁺]_i homeostasis in human autosomal-dominant polycystic kidney disease cells.

Tomilin, Viktor; Reif, Gail A; Zaika, Oleg; Wallace, Darren P; Pochynyuk, Oleh.

FASEB J ; 32(8): 4612-4623, 2018 08.

Article in English | MEDLINE | ID: mdl-29553832

12.

Periostin in the Kidney.

Wallace, Darren P.

Adv Exp Med Biol ; 1132: 99-112, 2019.

Article in English | MEDLINE | ID: mdl-31037629

13.

Human-Specific Abnormal Alternative Splicing of Wild-Type PKD1 Induces Premature Termination of Polycystin-1.

Lea, Wendy A; Parnell, Stephen C; Wallace, Darren P; Calvet, James P; Zelenchuk, Lesya V; Alvarez, Nehemiah S; Ward, Christopher J.

J Am Soc Nephrol ; 29(10): 2482-2492, 2018 10.

Article in English | MEDLINE | ID: mdl-30185468

14.

Periostin overexpression in collecting ducts accelerates renal cyst growth and fibrosis in polycystic kidney disease.

Raman, Archana; Parnell, Stephen C; Zhang, Yan; Reif, Gail A; Dai, Yuqiao; Khanna, Aditi; Daniel, Emily; White, Corey; Vivian, Jay L; Wallace, Darren P.

Am J Physiol Renal Physiol ; 315(6): F1695-F1707, 2018 12 01.

Article in English | MEDLINE | ID: mdl-30332313

15.

Corrigendum to "Ttc21b deficiency attenuates autosomal dominant polycystic kidney disease in a kidney tubular- and maturation-dependent manner." Kidney Int. 2022;102:577-591.

Wang, Wei; Silva, Luciane M; Wang, Henry H; Kavanaugh, Matthew A; Pottorf, Tana S; Allard, Bailey A; Jacobs, Damon T; Dong, Ruochen; Cornelius, Joseph T; Chaturvedi, Aakriti; Swenson-Fields, Katherine I; Fields, Timothy A; Pritchard, Michele T; Sharma, Madhulika; Slawson, Chad; Wallace, Darren P; Calvet, James P; Tran, Pamela V.

Kidney Int ; 103(6): 1202, 2023 Jun.

Article in English | MEDLINE | ID: mdl-37210199

16.

Corrigendum to "Ttc21b deficiency attenuates autosomal dominant polycystic kidney disease in a kidney tubular- and maturation-dependent manner." Kidney Int. 2022;102:577-591.

Wang, Wei; Silva, Luciane M; Wang, Henry H; Kavanaugh, Matthew A; Pottorf, Tana S; Allard, Bailey A; Jacobs, Damon T; Dong, Rouchen; Cornelius, Joseph T; Chaturvedi, Aakriti; Swenson-Fields, Katherine I; Fields, Timothy A; Pritchard, Michele T; Sharma, Madhulika; Slawson, Chad; Wallace, Darren P; Calvet, James P; Tran, Pamela V.

Kidney Int ; 103(2): 429, 2023 Feb.

Article in English | MEDLINE | ID: mdl-36681463

17.

Ouabain promotes partial epithelial to mesenchymal transition (EMT) changes in human autosomal dominant polycystic kidney disease (ADPKD) cells.

Venugopal, Jessica; McDermott, Jeffrey; Sanchez, Gladis; Sharma, Madhulika; Barbosa, Leandro; Reif, Gail A; Wallace, Darren P; Blanco, Gustavo.

Exp Cell Res ; 355(2): 142-152, 2017 06 15.

Article in English | MEDLINE | ID: mdl-28385574

18.

Integrin-Linked Kinase Signaling Promotes Cyst Growth and Fibrosis in Polycystic Kidney Disease.

Raman, Archana; Reif, Gail A; Dai, Yuqiao; Khanna, Aditi; Li, Xiaogang; Astleford, Lindsay; Parnell, Stephen C; Calvet, James P; Wallace, Darren P.

J Am Soc Nephrol ; 28(9): 2708-2719, 2017 Sep.

Article in English | MEDLINE | ID: mdl-28522687

19.

Insights into cellular and molecular basis for urinary tract infection in autosomal-dominant polycystic kidney disease.

Gao, Chao; Zhang, Long; Zhang, Ye; Wallace, Darren P; Lopez-Soler, Reynold I; Higgins, Paul J; Zhang, Wenzheng.

Am J Physiol Renal Physiol ; 313(5): F1077-F1083, 2017 Nov 01.

Article in English | MEDLINE | ID: mdl-28794066

20.

Increased YAP Activation Is Associated With Hepatic Cyst Epithelial Cell Proliferation in ARPKD/CHF.

Jiang, Lu; Sun, Lina; Edwards, Genea; Manley, Michael; Wallace, Darren P; Septer, Seth; Manohar, Chirag; Pritchard, Michele T; Apte, Udayan.

Gene Expr ; 17(4): 313-326, 2017 11 27.

Article in English | MEDLINE | ID: mdl-28915934

VHL Search Portal

Information and Knowledge for Health

Config filters

Your selection (0)

Export format:

Export:

Pkd2 Deficiency in Embryonic Aqp2 + Progenitor Cells Is Sufficient to Cause Severe Polycystic Kidney Disease.

Metabolomic profiling to identify early urinary biomarkers and metabolic pathway alterations in autosomal dominant polycystic kidney disease.

Accuracy and processing time of kidney volume measurement methods in rodents polycystic kidney disease models: superiority of semiautomated kidney segmentation.

The lonidamine derivative H2-gamendazole reduces cyst formation in polycystic kidney disease.

Expression of active B-Raf proto-oncogene in kidney collecting ducts induces cyst formation in normal mice and accelerates cyst growth in mice with polycystic kidney disease.

Ttc21b deficiency attenuates autosomal dominant polycystic kidney disease in a kidney tubular- and maturation-dependent manner.

Quinomycin A reduces cyst progression in polycystic kidney disease.

Epithelial Vasopressin Type-2 Receptors Regulate Myofibroblasts by a YAP-CCN2-Dependent Mechanism in Polycystic Kidney Disease.

Overexpression of TGF-ß1 induces renal fibrosis and accelerates the decline in kidney function in polycystic kidney disease.

MCP-1 promotes detrimental cardiac physiology, pulmonary edema, and death in the cpk model of polycystic kidney disease.

Deficient transient receptor potential vanilloid type 4 function contributes to compromised [Ca²⁺]_i homeostasis in human autosomal-dominant polycystic kidney disease cells.

Periostin in the Kidney.

Human-Specific Abnormal Alternative Splicing of Wild-Type PKD1 Induces Premature Termination of Polycystin-1.

Periostin overexpression in collecting ducts accelerates renal cyst growth and fibrosis in polycystic kidney disease.

Corrigendum to "Ttc21b deficiency attenuates autosomal dominant polycystic kidney disease in a kidney tubular- and maturation-dependent manner." Kidney Int. 2022;102:577-591.

Corrigendum to "Ttc21b deficiency attenuates autosomal dominant polycystic kidney disease in a kidney tubular- and maturation-dependent manner." Kidney Int. 2022;102:577-591.

Ouabain promotes partial epithelial to mesenchymal transition (EMT) changes in human autosomal dominant polycystic kidney disease (ADPKD) cells.

Integrin-Linked Kinase Signaling Promotes Cyst Growth and Fibrosis in Polycystic Kidney Disease.

Insights into cellular and molecular basis for urinary tract infection in autosomal-dominant polycystic kidney disease.

Increased YAP Activation Is Associated With Hepatic Cyst Epithelial Cell Proliferation in ARPKD/CHF.