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1.
Inhibition of Dihydroorotate Dehydrogenase Overcomes Differentiation Blockade in Acute Myeloid Leukemia.
Cell
; 167(1): 171-186.e15, 2016 Sep 22.
Article
in English
| MEDLINE | ID: mdl-27641501
2.
Advancing Biological Understanding and Therapeutics Discovery with Small-Molecule Probes.
Cell
; 161(6): 1252-65, 2015 Jun 04.
Article
in English
| MEDLINE | ID: mdl-26046436
3.
Diversity-oriented synthesis yields novel multistage antimalarial inhibitors.
Nature
; 538(7625): 344-349, 2016 Oct 20.
Article
in English
| MEDLINE | ID: mdl-27602946
4.
DNA Barcoding a Complete Matrix of Stereoisomeric Small Molecules.
J Am Chem Soc
; 141(26): 10225-10235, 2019 07 03.
Article
in English
| MEDLINE | ID: mdl-31184885
5.
Synergistic Effects of Stereochemistry and Appendages on the Performance Diversity of a Collection of Synthetic Compounds.
J Am Chem Soc
; 140(37): 11784-11790, 2018 09 19.
Article
in English
| MEDLINE | ID: mdl-30133283
6.
Toward performance-diverse small-molecule libraries for cell-based phenotypic screening using multiplexed high-dimensional profiling.
Proc Natl Acad Sci U S A
; 111(30): 10911-6, 2014 Jul 29.
Article
in English
| MEDLINE | ID: mdl-25024206
7.
Real-Time Biological Annotation of Synthetic Compounds.
J Am Chem Soc
; 138(28): 8920-7, 2016 07 20.
Article
in English
| MEDLINE | ID: mdl-27398798
8.
Validation of ferroptosis in canine cancer cells to enable comparative oncology and translational medicine.
bioRxiv
; 2024 Apr 30.
Article
in English
| MEDLINE | ID: mdl-38746359
9.
Mapping the landscape of genetic dependencies in chordoma.
Nat Commun
; 14(1): 1933, 2023 04 06.
Article
in English
| MEDLINE | ID: mdl-37024492
10.
Reference compounds for characterizing cellular injury in high-content cellular morphology assays.
Nat Commun
; 14(1): 1364, 2023 03 13.
Article
in English
| MEDLINE | ID: mdl-36914634
11.
Application of MCAT questions as a testing tool and evaluation metric for knowledge graph-based reasoning systems.
Clin Transl Sci
; 14(5): 1719-1724, 2021 09.
Article
in English
| MEDLINE | ID: mdl-33742785
12.
Targeted brachyury degradation disrupts a highly specific autoregulatory program controlling chordoma cell identity.
Cell Rep Med
; 2(1): 100188, 2021 01 19.
Article
in English
| MEDLINE | ID: mdl-33521702
13.
Small-molecule targeting of brachyury transcription factor addiction in chordoma.
Nat Med
; 25(2): 292-300, 2019 02.
Article
in English
| MEDLINE | ID: mdl-30664779
14.
Genome-scale analysis identifies paralog lethality as a vulnerability of chromosome 1p loss in cancer.
Nat Genet
; 50(7): 937-943, 2018 07.
Article
in English
| MEDLINE | ID: mdl-29955178
15.
A dataset of images and morphological profiles of 30 000 small-molecule treatments using the Cell Painting assay.
Gigascience
; 6(12): 1-5, 2017 12 01.
Article
in English
| MEDLINE | ID: mdl-28327978
16.
Divergent Synthesis and Real-Time Biological Annotation of Optically Active Tetrahydrocyclopenta[c]pyranone Derivatives.
Org Lett
; 18(24): 6280-6283, 2016 12 16.
Article
in English
| MEDLINE | ID: mdl-27978655
17.
Harnessing Connectivity in a Large-Scale Small-Molecule Sensitivity Dataset.
Cancer Discov
; 5(11): 1210-23, 2015 Nov.
Article
in English
| MEDLINE | ID: mdl-26482930
18.
Automated Structure-Activity Relationship Mining: Connecting Chemical Structure to Biological Profiles.
J Biomol Screen
; 19(5): 738-48, 2014 Jun.
Article
in English
| MEDLINE | ID: mdl-24710340
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