ABSTRACT
INTRODUCTION: Congenital atrioventricular block is diagnosed in uterine life, at birth, or early in life. Atrioventricular blocks can be life threatening immediately at birth so urgent pacemaker implantation techniques are requested. Reasons can be cardiac or non-cardiac, but regardless of the reason, operations are challenging. We aimed to present technical procedure and operative results of pacemaker implantation in neonates. MATERIALS AND METHODS: Between June 2014 and February 2021, 10 neonates who had congenital atrioventricular block underwent surgical operation to implant permanent epicardial pacemaker by using minimally invasive technique. Six of the patients were female and four of them were male. Mean age was 4.3 days (0-11), while three of them were operated on the day of birth. Mean weight was 2533 g (1200-3300). RESULTS: Operations were achieved through subxiphoidal minimally skin incision. Epicardial 25 mm length dual leads were implanted on right ventricular surface and generators were fixed on the right (seven patients) or left (three patients) diaphragmatic surface by incising pleura. There were no complication, morbidity, and mortality related to surgery. CONCLUSION: Few studies have characterised the surgical outcomes following epicardial permanent pacemaker implantation in neonates. The surgical approach is attractive and compelling among professionals so we aimed to present the techniques and results in patients who required permanent pacemaker implantation in the first month of life.
Subject(s)
Atrioventricular Block , Cardiac Surgical Procedures , Pacemaker, Artificial , Atrioventricular Block/etiology , Cardiac Pacing, Artificial/methods , Cardiac Surgical Procedures/adverse effects , Child, Preschool , Delivery Rooms , Female , Humans , Infant, Newborn , Male , Pacemaker, Artificial/adverse effects , PregnancyABSTRACT
Congenital Long QT Syndrome (LQTS) is a dangerous arrhythmic disorder that can be diagnosed in children with bradycardia. It is characterised by a prolonged QT interval and torsades de pointes that may cause sudden death. Long QT syndrome is an ion channelopathy with complex molecular and physiological infrastructure. Unlike the acquired type, congenital LQTS has a genetic inheritance and it may be diagnosed by syncope, stress in activity, cardiac dysfunction, sudden death or sometimes incidentally. Permanent pacemaker implantation is required for LQTS with resistant bradycardia even in children to resolve symptoms and avoid sudden death.
Subject(s)
Long QT Syndrome , Pacemaker, Artificial , Torsades de Pointes , Child , Death, Sudden, Cardiac , Electrocardiography , Humans , Long QT Syndrome/genetics , Long QT Syndrome/therapyABSTRACT
OBJECTIVE: Apheresis is performed for treatment of numerous diseases by removing auto-antibodies, antigen-antibody complexes, allo-antibodies, paraproteins, non-Ig proteins, toxins, exogenous poisons. In current study, we present our experience of using therapeutic plasma exchange (TPE) in patients with different types of clinical scenarios. METHODS: Between January 2013 and May 2016, we retrospectively presented the results of 64 patients in whom postoperative TPE was performed in ICU setting after cardiac surgery. Patients were grouped into four as; 1-sepsis (n = 26), 2-hepatorenal syndrome(n = 24), 3-antibody mediated rejection(AMR) following heart transplantation(n = 4) and 4-right heart failure(RHF) after left ventricular asist device(LVAD)(n = 10). Hemodynamic parameters were monitored constantly, pre- and post-procedure peripheral blood tests including renal and liver functions and daily complete blood count (CBC), sedimentation, C-reactive protein and procalcitonin (ng/ml) levels were studied. RESULTS: The mean age was 61 ± 17.67 years old and 56.25% (n = 36) were male. Mean Pre TPE left ventricular ejection fraction (LVEF) (%), central venous pressure (CVP)(mmHg) pulmonary capillary wedge pressure (PCWP)(mmHg) and pulmonary arterial pressure (PAP)(mmHg) were measured as 41.8 ± 8.1, 15.5 ± 4.4, 17.3 ± 3.24 and 39.9 ± 5.4, respectively. Procalcitonin (ng/ml) level of patients undergoing TPE due to sepsis was significantly reduced from 873 ± 401 ng/ml to 248 ± 132 ng/ml. Seventeen (26.5%) patients died in hospital during treatment, mean length of intensive care unit (ICU) stay(days) was 13.2 ± 5.1. CONCLUSION: This study shows that TEP is a safe and feasible treatment modality in patients with different types of complications after cardiac surgery and hopefully this study will lead to new utilization areas.
Subject(s)
Cardiovascular Surgical Procedures , Plasmapheresis , Procedures and Techniques Utilization , Aged , Female , Graft Rejection/pathology , Heart Failure/complications , Heart Transplantation , Heart-Assist Devices , Hepatorenal Syndrome/complications , Humans , Male , Middle Aged , Probability , Prosthesis Implantation , Sepsis/complications , Sepsis/pathology , Survival Analysis , Systemic Inflammatory Response Syndrome/complications , Systemic Inflammatory Response Syndrome/pathologyABSTRACT
Interrupted aortic arch (IAA) is a very rare pathology characterized by luminal discontinuity between ascending and descending aorta. IAA is commonly treated in pediatric ages, but the surgery is rarely used for adult patients. In this case report, we aimed to present a successful surgery in a young woman in whom IAA was diagnosed during pregnancy.
Subject(s)
Aorta, Thoracic/surgery , Blood Vessel Prosthesis Implantation , Pregnancy Complications, Cardiovascular/surgery , Vascular Malformations/surgery , Adult , Aorta, Thoracic/abnormalities , Aorta, Thoracic/diagnostic imaging , Aortography/methods , Blood Vessel Prosthesis , Blood Vessel Prosthesis Implantation/instrumentation , Female , Humans , Hypertension/diagnosis , Hypertension/etiology , Live Birth , Postnatal Care , Pregnancy , Pregnancy Complications, Cardiovascular/diagnosis , Prosthesis Design , Tomography, X-Ray Computed , Treatment Outcome , Vascular Malformations/complications , Vascular Malformations/diagnosisABSTRACT
BACKGROUND CONTEXT: The North American Spine Society (NASS) publishes clinical guidelines that are taken into consideration worldwide by clinicians who have a special interest in spinal surgery. The Appraisal of Guidelines for Research and Evaluation (AGREE) II is the second version of the original AGREE instrument to assess the quality of guidelines in terms of development process. This appraisal aims to evaluate each individual NASS guideline using AGREE II tool to demonstrate its methodologic robust and weakness. PURPOSE: To evaluate the quality of the clinical practice guidelines published by the NASS. STUDY DESIGN: Four appraisers used the AGREE II guideline evaluation instrument to evaluate the NASS guidelines. METHODS: All six guidelines available on the NASS web site as of July 1, 2014 were evaluated. Four reviewers independently assessed these guidelines using the AGREE II instrument. The instrument standardizes the quantitative assessment of quality for a guideline's development process across six domains that include: scope and purpose, stakeholder involvement, rigor of development, clarity and presentation, applicability, and editorial independence. Additionally, each reviewer rated the overall quality of the guidelines. RESULTS: Overall results for the AGREE II domains across all six guidelines were: scope and purpose (median score, 94.4%), stakeholder involvement (median score, 56.9%), rigor of development (median score, 91.7%), clarity of presentation (median score, 94.4%), applicability (median score, 60.9%), and editorial independence (median score, 71.9%). CONCLUSIONS: Our study showed that the quality of the NASS guidelines needs some improvement. There is a critical need for broader stakeholder involvement including patient representatives and health economists. Consideration of resource implications and monitoring process and standardization of how recommendations are implemented need to be improved. Studies analyzing facilitators and barriers would be helpful for future NASS guidelines.
Subject(s)
Orthopedic Procedures/standards , Practice Guidelines as Topic/standards , Societies, Medical/standards , Humans , Research Design/standards , Spine/surgery , United StatesABSTRACT
The use of percutaneous devices is commonplace for the treatment of many congenital heart defects. However, there are some situations where procedure-related complications are encountered and surgical help is required to ameliorate this issue. Vascular injury due to transcatheter intervention is a significant and challenging complication and occasionally requires surgical approach. In this case report, we aimed to present successful surgical management of vascular injuries associated with percutaneous interventions in children.