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1.

The bone microenvironment invigorates metastatic seeds for further dissemination.

Zhang, Weijie; Bado, Igor L; Hu, Jingyuan; Wan, Ying-Wooi; Wu, Ling; Wang, Hai; Gao, Yang; Jeong, Hyun-Hwan; Xu, Zhan; Hao, Xiaoxin; Lege, Bree M; Al-Ouran, Rami; Li, Lucian; Li, Jiasong; Yu, Liqun; Singh, Swarnima; Lo, Hin Ching; Niu, Muchun; Liu, Jun; Jiang, Weiyu; Li, Yi; Wong, Stephen T C; Cheng, Chonghui; Liu, Zhandong; Zhang, Xiang H-F.

Cell ; 184(9): 2471-2486.e20, 2021 04 29.

Article in English | MEDLINE | ID: mdl-33878291

2.

Spliceosome-targeted therapies trigger an antiviral immune response in triple-negative breast cancer.

Bowling, Elizabeth A; Wang, Jarey H; Gong, Fade; Wu, William; Neill, Nicholas J; Kim, Ik Sun; Tyagi, Siddhartha; Orellana, Mayra; Kurley, Sarah J; Dominguez-Vidaña, Rocio; Chung, Hsiang-Ching; Hsu, Tiffany Y-T; Dubrulle, Julien; Saltzman, Alexander B; Li, Heyuan; Meena, Jitendra K; Canlas, Gino M; Chamakuri, Srinivas; Singh, Swarnima; Simon, Lukas M; Olson, Calla M; Dobrolecki, Lacey E; Lewis, Michael T; Zhang, Bing; Golding, Ido; Rosen, Jeffrey M; Young, Damian W; Malovannaya, Anna; Stossi, Fabio; Miles, George; Ellis, Matthew J; Yu, Lihua; Buonamici, Silvia; Lin, Charles Y; Karlin, Kristen L; Zhang, Xiang H-F; Westbrook, Thomas F.

Cell ; 184(2): 384-403.e21, 2021 01 21.

Article in English | MEDLINE | ID: mdl-33450205

3.

Lung mesenchymal cells elicit lipid storage in neutrophils that fuel breast cancer lung metastasis.

Li, Peishan; Lu, Ming; Shi, Jiayuan; Gong, Zheng; Hua, Li; Li, Qing; Lim, Bora; Zhang, Xiang H-F; Chen, Xiaowen; Li, Sheng; Shultz, Leonard D; Ren, Guangwen.

Nat Immunol ; 21(11): 1444-1455, 2020 11.

Article in English | MEDLINE | ID: mdl-32958928

4.

Serpins promote cancer cell survival and vascular co-option in brain metastasis.

Valiente, Manuel; Obenauf, Anna C; Jin, Xin; Chen, Qing; Zhang, Xiang H-F; Lee, Derek J; Chaft, Jamie E; Kris, Mark G; Huse, Jason T; Brogi, Edi; Massagué, Joan.

Cell ; 156(5): 1002-16, 2014 Feb 27.

Article in English | MEDLINE | ID: mdl-24581498

5.

Selection of bone metastasis seeds by mesenchymal signals in the primary tumor stroma.

Zhang, Xiang H-F; Jin, Xin; Malladi, Srinivas; Zou, Yilong; Wen, Yong H; Brogi, Edi; Smid, Marcel; Foekens, John A; Massagué, Joan.

Cell ; 154(5): 1060-1073, 2013 Aug 29.

Article in English | MEDLINE | ID: mdl-23993096

6.

A poised chromatin platform for TGF-ß access to master regulators.

Xi, Qiaoran; Wang, Zhanxin; Zaromytidou, Alexia-Ileana; Zhang, Xiang H-F; Chow-Tsang, Lai-Fong; Liu, Jing X; Kim, Hyesoo; Barlas, Afsar; Manova-Todorova, Katia; Kaartinen, Vesa; Studer, Lorenz; Mark, Willie; Patel, Dinshaw J; Massagué, Joan.

Cell ; 147(7): 1511-24, 2011 Dec 23.

Article in English | MEDLINE | ID: mdl-22196728

7.

Engineering small-molecule and protein drugs for targeting bone tumors.

Wang, Yixian; Wang, Chenhang; Xia, Meng; Tian, Zeru; Zhou, Joseph; Berger, Julian Meyer; Zhang, Xiang H-F; Xiao, Han.

Mol Ther ; 32(5): 1219-1237, 2024 May 01.

Article in English | MEDLINE | ID: mdl-38449313

8.

Unravelling spatial gene associations with SEAGAL: a Python package for spatial transcriptomics data analysis and visualization.

Wang, Linhua; Liu, Chaozhong; Gao, Yang; Zhang, Xiang H-F; Liu, Zhandong.

Bioinformatics ; 39(7)2023 07 01.

Article in English | MEDLINE | ID: mdl-37436699

9.

Bone Endosteal Mimics Regulates Breast Cancer Development and Phenotype.

Ben Ghedalia Peled, Noa; Hoffman, Dane K; Barsky, Livnat; Zer, Noy S; Amar, Katya; Rapaport, Hanna; Gheber, Levi A; Zhang, Xiang H-F; Vago, Razi.

Biomacromolecules ; 25(4): 2338-2347, 2024 Apr 08.

Article in English | MEDLINE | ID: mdl-38499995

10.

Tumor self-seeding by circulating cancer cells.

Kim, Mi-Young; Oskarsson, Thordur; Acharyya, Swarnali; Nguyen, Don X; Zhang, Xiang H-F; Norton, Larry; Massagué, Joan.

Cell ; 139(7): 1315-26, 2009 Dec 24.

Article in English | MEDLINE | ID: mdl-20064377

11.

WNT/TCF signaling through LEF1 and HOXB9 mediates lung adenocarcinoma metastasis.

Nguyen, Don X; Chiang, Anne C; Zhang, Xiang H-F; Kim, Juliet Y; Kris, Mark G; Ladanyi, Marc; Gerald, William L; Massagué, Joan.

Cell ; 138(1): 51-62, 2009 Jul 10.

Article in English | MEDLINE | ID: mdl-19576624

12.

Metabolic enzyme PFKFB4 activates transcriptional coactivator SRC-3 to drive breast cancer.

Dasgupta, Subhamoy; Rajapakshe, Kimal; Zhu, Bokai; Nikolai, Bryan C; Yi, Ping; Putluri, Nagireddy; Choi, Jong Min; Jung, Sung Y; Coarfa, Cristian; Westbrook, Thomas F; Zhang, Xiang H-F; Foulds, Charles E; Tsai, Sophia Y; Tsai, Ming-Jer; O'Malley, Bert W.

Nature ; 556(7700): 249-254, 2018 04.

Article in English | MEDLINE | ID: mdl-29615789

13.

The tumor-immune ecosystem in shaping metastasis.

Gao, Yang; Rosen, Jeffrey M; Zhang, Xiang H-F.

Am J Physiol Cell Physiol ; 324(3): C707-C717, 2023 03 01.

Article in English | MEDLINE | ID: mdl-36717100

14.

TGFbeta primes breast tumors for lung metastasis seeding through angiopoietin-like 4.

Padua, David; Zhang, Xiang H-F; Wang, Qiongqing; Nadal, Cristina; Gerald, William L; Gomis, Roger R; Massagué, Joan.

Cell ; 133(1): 66-77, 2008 Apr 04.

Article in English | MEDLINE | ID: mdl-18394990

15.

Dynamic regulation of alternative splicing by silencers that modulate 5' splice site competition.

Yu, Yang; Maroney, Patricia A; Denker, John A; Zhang, Xiang H-F; Dybkov, Olexandr; Lührmann, Reinhard; Jankowsky, Eckhard; Chasin, Lawrence A; Nilsen, Timothy W.

Cell ; 135(7): 1224-36, 2008 Dec 26.

Article in English | MEDLINE | ID: mdl-19109894

16.

Mutual regulation of tumour vessel normalization and immunostimulatory reprogramming.

Tian, Lin; Goldstein, Amit; Wang, Hai; Ching Lo, Hin; Sun Kim, Ik; Welte, Thomas; Sheng, Kuanwei; Dobrolecki, Lacey E; Zhang, Xiaomei; Putluri, Nagireddy; Phung, Thuy L; Mani, Sendurai A; Stossi, Fabio; Sreekumar, Arun; Mancini, Michael A; Decker, William K; Zong, Chenghang; Lewis, Michael T; Zhang, Xiang H-F.

Nature ; 544(7649): 250-254, 2017 04 13.

Article in English | MEDLINE | ID: mdl-28371798

17.

Elevated NRAS expression during DCIS is a potential driver for progression to basal-like properties and local invasiveness.

Zheng, Ze-Yi; Elsarraj, Hanan; Lei, Jonathan T; Hong, Yan; Anurag, Meenakshi; Feng, Long; Kennedy, Hilda; Shen, Yichao; Lo, Flora; Zhao, Zifan; Zhang, Bing; Zhang, Xiang H-F; Tawfik, Ossama W; Behbod, Fariba; Chang, Eric C.

Breast Cancer Res ; 24(1): 68, 2022 10 18.

Article in English | MEDLINE | ID: mdl-36258226

18.

Multi-omic molecular profiling reveals potentially targetable abnormalities shared across multiple histologies of brain metastasis.

Fukumura, Kazutaka; Malgulwar, Prit Benny; Fischer, Grant M; Hu, Xiaoding; Mao, Xizeng; Song, Xingzhi; Hernandez, Sharia D; Zhang, Xiang H-F; Zhang, Jianhua; Parra, Edwin Roger; Yu, Dihua; Debeb, Bisrat G; Davies, Michael A; Huse, Jason T.

Acta Neuropathol ; 141(2): 303-321, 2021 02.

Article in English | MEDLINE | ID: mdl-33394124

19.

Molecules in the blood of older people promote cancer spread.

Wang, Hai; Zhang, Xiang H-F.

Nature ; 585(7824): 187-188, 2020 09.

Article in English | MEDLINE | ID: mdl-32814911

20.

The spliceosome is a therapeutic vulnerability in MYC-driven cancer.

Hsu, Tiffany Y-T; Simon, Lukas M; Neill, Nicholas J; Marcotte, Richard; Sayad, Azin; Bland, Christopher S; Echeverria, Gloria V; Sun, Tingting; Kurley, Sarah J; Tyagi, Siddhartha; Karlin, Kristen L; Dominguez-Vidaña, Rocio; Hartman, Jessica D; Renwick, Alexander; Scorsone, Kathleen; Bernardi, Ronald J; Skinner, Samuel O; Jain, Antrix; Orellana, Mayra; Lagisetti, Chandraiah; Golding, Ido; Jung, Sung Y; Neilson, Joel R; Zhang, Xiang H-F; Cooper, Thomas A; Webb, Thomas R; Neel, Benjamin G; Shaw, Chad A; Westbrook, Thomas F.

Nature ; 525(7569): 384-8, 2015 Sep 17.

Article in English | MEDLINE | ID: mdl-26331541

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