The influence of bone loss on the three adult age markers of the innominate.

To evaluate the influence of bone loss on the three adult age markers of the innominate, 30 males and 30 females aged between 16 and 80 years coming from the British Coventry collection were analyzed. The pubic symphysis, auricular surface, and acetabulum age variables were evaluated following the descriptions of Schmitt, Buckberry-Chamberlain, and Rissech, respectively. The second metacarpal cortical index was used to evaluate bone loss. Possible sexual differences in metrical variables were explored by a Student t-test taking into account the entire sample. The possible relationships between the cortical index and the three age methods' stages were assessed by the Kruskall-Wallis test and Spearman's correlation coefficient. There were no sexual differences in the cortical index. In general, we observed no significant differences between the cortical index in the different stages of the pubic symphysis, auricular surface, or acetabulum variables in men and women. Most correlation coefficients are negatives, and their absolute values are between 0.001 and 0.44, indicating an extremely low influence of bone loss on the analyzed variables. Our findings suggest little influence of bone loss in the three ageing methods. However, further research on this topic is necessary. This is the first study to analyze the influence of bone loss in the ageing changes undergone by the variables of the three adult age indicators of the innominate taking into account both sexes.

Perimortem trauma in King Richard III: a skeletal analysis.

BACKGROUND: Richard III was the last king of England to die in battle, but how he died is unknown. On Sept 4, 2012, a skeleton was excavated in Leicester that was identified as Richard. We investigated the trauma to the skeleton with modern forensic techniques, such as conventional CT and micro-CT scanning, to characterise the injuries and establish the probable cause of death. METHODS: We assessed age and sex through direct analysis of the skeleton and from CT images. All bones were examined under direct light and multi-spectral illumination. We then scanned the skeleton with whole-body post-mortem CT. We subsequently examined bones with identified injuries with micro-CT. We deemed that trauma was perimortem when we recorded no evidence of healing and when breakage characteristics were typical of fresh bone. We used previous data to identify the weapons responsible for the recorded injuries. FINDINGS: The skeleton was that of an adult man with a gracile build and severe scoliosis of the thoracic spine. Standard anthropological age estimation techniques based on dry bone analysis gave an age range between 20s and 30s. Standard post-mortem CT methods were used to assess rib end morphology, auricular surfaces, pubic symphyseal face, and cranial sutures, to produce a multifactorial narrower age range estimation of 30-34 years. We identified nine perimortem injuries to the skull and two to the postcranial skeleton. We identified no healed injuries. The injuries were consistent with those created by weapons from the later medieval period. We could not identify the specific order of the injuries, because they were all distinct, with no overlapping wounds. Three of the injuries-two to the inferior cranium and one to the pelvis-could have been fatal. INTERPRETATION: The wounds to the skull suggest that Richard was not wearing a helmet, although the absence of defensive wounds on his arms and hands suggests he was still otherwise armoured. Therefore, the potentially fatal pelvis injury was probably received post mortem, meaning that the most likely injuries to have caused his death are the two to the inferior cranium. FUNDING: The University of Leicester.

Ageing and disease risk factors: A new paleoepidemiological methodology for understanding disease in the past.

OBJECTIVES: To outline a methodology that enables the reconstruction of age-related disease risk in past societies. MATERIALS: Modern epidemiological evidence considering risk factors for age-related disease is combined with contextual information about an archaeological society of interest. METHODS: Data gathered is used to create a qualitative population-specific risk model for the disease of interest. To provide a case study, a risk model is constructed for Chronic Obstructive Pulmonary Disease (COPD) in the Eastern English Bronze Age. RESULTS: This enables the first rigorous approach to reconstructing age-related disease risk in the past. A risk model shows a high degree of COPD risk in the Eastern English Bronze Age, with a major contribution from indoor airborne pollution and agricultural practices. SIGNIFICANCE: This represents a significant new approach in human paleopathology, facilitating understanding of the occurrence of a wide variety of diseases in the past, without the need for well-preserved skeletons of identified elderly individuals. LIMITATIONS: The risk models generated are, of necessity, qualitative rather than quantitative, since we are unable to calculate the size of risk factors in the past with certainty. SUGGESTIONS FOR FURTHER RESEARCH: The methodology could be applied to a wide variety of diseases and for many past societies.

Increasing confidence in paleopathological diagnosis - Application of the Istanbul terminological framework.

Paleopathological reporting is hampered by a lack of precision in the confidence levels of diagnosis. In this article, we recommend the application of a slightly modified system of nomenclature ratified by the UN and widely used in forensic medicine for the identification of torture. The application of this terminological framework within paleopathology would encourage consistency between practitioners and enhance the reliability of comparisons between cases.

Identification of the remains of King Richard III.

In 2012, a skeleton was excavated at the presumed site of the Grey Friars friary in Leicester, the last-known resting place of King Richard III. Archaeological, osteological and radiocarbon dating data were consistent with these being his remains. Here we report DNA analyses of both the skeletal remains and living relatives of Richard III. We find a perfect mitochondrial DNA match between the sequence obtained from the remains and one living relative, and a single-base substitution when compared with a second relative. Y-chromosome haplotypes from male-line relatives and the remains do not match, which could be attributed to a false-paternity event occurring in any of the intervening generations. DNA-predicted hair and eye colour are consistent with Richard's appearance in an early portrait. We calculate likelihood ratios for the non-genetic and genetic data separately, and combined, and conclude that the evidence for the remains being those of Richard III is overwhelming.