Physiological Effects of Handling in Moderate to Late Preterm Infants Receiving Neonatal Intensive Care.

BACKGROUND: Of all preterm births, approximately 82% are moderate to late preterm. Moderate to late preterm infants are often treated like full-term infants despite their physiological and metabolic immaturity, increasing their risk for mortality and morbidity. PURPOSE: To describe the relationship between routine caregiving methods and physiological markers of stress and hypoxemia in infants born between 32 and 36 6/7 weeks' gestation. METHODS: This descriptive study used a prospective observational design to examine the relationship between routine caregiving patterns (single procedure vs clustered care) and physiological markers of stress and hypoxemia such as regional oxygen saturation, quantified as renal and cerebral regional oxygen saturation (StO 2 ), systemic oxygen saturation (Sp o2 ), and heart rate (HR) in moderate to late preterm infants. Renal and cerebral StO 2 was measured using near-infrared spectroscopy during a 6-hour study period. Sp o2 and HR were measured using pulse oximetry. RESULTS: A total of 231 procedures were captured in 37 participants. We found greater alterations in cerebral StO 2 , renal StO 2 , Sp o2 , and HR when routine procedures were performed consecutively in clusters than when procedures were performed singly or separately. IMPLICATIONS FOR PRACTICE AND RESEARCH: Our results suggest that the oxygen saturation and HR of moderate to late preterm infants were significantly altered when exposed to routine procedures that were performed consecutively, in clusters, compared with when exposed to procedures that were performed singly or separately. Adequately powered randomized controlled trials are needed to determine the type of caregiving patterns that will optimize the health outcomes of this vulnerable population.

Twice weekly prophylaxis with trimethoprim/sulfamethoxazole for Pneumocystis jirovecii pneumonia in pediatric oncology patients.

Current recommendations for prophylaxis of Pneumocystis jirovecii pneumonia in oncology patients include administration of trimethoprim/sulfamethoxazole (TMP/SMX) three times weekly or the same total weekly dose given daily. The primary objective of this study was to evaluate the efficacy of two consecutive days per week of TMP/SMX for prevention of Pneumocystis jirovecii pneumonia (PJP) in pediatric oncology patients. A retrospective cohort, single-center analysis was conducted in oncology patients 21 years and younger who received TMP/SMX for PJP prophylaxis between February 1, 2013 and July 31, 2017. Changes to the prophylaxis regimen were documented and analyzed. A total of 322 patients received TMP/SMX on two consecutive days per week for PJP prevention, of whom four had confirmed PJP (1.3%). Neutropenia was the most common reason for switching to alternative prophylaxis therapy (11.5%). Two consecutive prophylaxis days with TMP/SMX may be insufficient to prevent PJP in children with hematologic malignancies. Neutropenia remains a barrier for TMP/SMX use for PJP prophylaxis. Further studies to compare PJP incidence in children receiving alternative prophylaxis regimens should be considered.

Comparison of Protonics™ Knee Brace With Sport Cord on Knee Pain and Function in Patients With Patellofemoral Pain Syndrome: A Randomized Controlled Trial.

CONTEXT: Protonics™ knee brace has been suggested as an intervention for patients with patellofemoral pain syndrome. However, the effectiveness of this knee brace compared with traditional conservative methods knee rehabilitation is lacking. OBJECTIVE: To compare the effect of Protonics™ knee brace versus sport cord on knee pain and function in patients with patellofemoral pain syndrome. DESIGN: Randomized controlled trial. SETTING: Loma Linda University. PARTICIPANTS: There were 41 subjects with patellofemoral pain with a mean age of 28.8 (5.0) years and body mass index of 25.6 (4.7) kg/m2 participated in the study. INTERVENTION: Subjects were randomized to 1 of 2 treatment groups, the Protonics™ knee brace (n = 21) or the sport cord (n = 20) to complete a series of resistance exercises over the course of 4 weeks. MAIN OUTCOME MEASURES: Both groups were evaluated according to the following clinical outcomes: anterior pelvic tilt, hip internal/external rotation, and iliotibial band flexibility. The following functional outcomes were also assessed: Global Rating of Change Scale, the Kujala score, the Numeric Pain Rating Scale, and the lateral step-down test. RESULTS: Both groups showed significant improvement in the outcome measures. However, the Protonics™ knee brace was more effective than the sport cord for the Global Rating of Change Scale over time (immediate 1.0 [2.1] vs post 2 wk 3.0 [2.2] vs 4 wk 4.6 [2.3] in the Protonics™ brace compared with 0.0 [2.1] vs 1.3 [2.2] vs 3.0 [2.3] in the sport cord, P < .01), suggesting greater satisfaction. CONCLUSIONS: Both study groups had significant improvements in the clinical and functional symptoms of patellofemoral pain. The Protonics™ knee brace group was significantly more satisfied with their outcome. However, the sport cord may be a more feasible and cost-effective method that yields similar results in patients with patellofemoral pain syndrome.

Safety of Peripheral Line Administration of 3% Hypertonic Saline and Mannitol in the Emergency Department.

BACKGROUND: Hypertonic saline (HTS) and mannitol are frequently utilized in the emergency department (ED) to manage elevations in intracranial pressure (ICP). OBJECTIVE: The objective of this study was to compare the incidence of extravasation injury when HTS or mannitol was administered via peripheral i.v. line (PIV). METHODS: This retrospective cohort study evaluated adult and pediatric patients given either 3% HTS or mannitol via PIV while in the ED. The primary outcome was extravasation incidence. RESULTS: One hundred and ninety-two patients were included, of which 85 (44%) received HTS and 107 (56%) received mannitol. Patients who received HTS were younger (27.5 ± 24.3 years vs. 53.9 ± 22.3 years; p < 0.001); 55.3% of patients given HTS received it for traumatic brain injury (TBI) versus 38.3% of patients given mannitol (p = 0.021); and 44.9% of patients given mannitol received it for intracerebral hemorrhage versus 21.2% of patients given HTS (p = 0.001). There was no incidence of extravasation in either group. Patients who received HTS had lower ICP measurement 24 h post admission (2.107 ± 5.5 mm Hg vs. 4.236 ± 8.1 mm Hg; p = 0.047) and higher Glasgow Coma Scale (GCS) score upon discharge (GCS 14; interquartile range [IQR] 3-15 vs. GCS 3; IQR 3-14.2; p = 0.004). In-hospital mortality was higher in the mannitol group (54.7% vs. 32.9%; p = 0.003). Duration of mechanical ventilation was shorter in those patients who received HTS (1 day; IQR 0-56 days vs. 2 days; IQR 0-56 days; p = 0.023). CONCLUSIONS: There were no incidences of extravasation among patients given 3% HTS or mannitol. Clinicians should reconsider recommendations to restrict HTS or mannitol to central lines.

Spiritual Care at the Bedside: Are We Practicing What We Preach?

Little is known about how nurses' personal spirituality and religious (S/R) beliefs impact their spiritual care of patients. An online survey was used to collect data from 445 nurses, assessing facets of religiosity, their opinions about introducing S/R during patient care, demographic, and work-related variables. Findings indicated that even in a sample of Christian nurses who scored high on religiousness measures, spiritual care is infrequent. Nurses' opinions about whether it was appropriate to initiate S/R conversation, self-disclosure, and prayer were associated with aspects of nurse religiosity. Nurses working in a faith-based organization were more likely to believe they could initiate S/R conversation and offer prayer.

Nurse opinions about initiating spiritual conversation and prayer in patient care.

AIM: The aim of this study was to understand nurses' opinions about initiating spiritual or religious conversation during patient care and to measure how these perspectives are associated with demographic, religious and work-related characteristics. BACKGROUND: Nurses are expected to provide spiritual care and do so in diverse ways. Little is known about how nurses think about initiating spiritual or religious discourse. DESIGN: Cross-sectional, quantitative. METHODS: Online survey methods allowed data collection from 445 nurses. The survey, accessed from the homepage of the Journal of Christian Nursing for 6 months beginning June 2015, included scales measuring various facets of religiosity, and items assessing nurse opinions about introducing spirituality or religion during patient care and demographic and work-related variables. Variables showing significant associations with Nurse Opinion items in bivariate analyses were examined using binary logistic regression. RESULTS: About 90% of participants believed it appropriate to initiate conversation about spirituality/religion and nearly three-quarters thought it appropriate to self-disclose spirituality/religion or offer prayer under certain circumstances or anytime. All personal religiosity indicators except tentativeness of belief were found to be associated with responses to Nurse Opinion items. That is, higher religiosity was associated with opinion one could initiate such conversations, whereas lower religiosity was associated with waiting for patients to initiate. Nurses working in a faith-based organization were 276% more likely to believe they could initiate such conversation and 153% more likely to think they could initiate an offer of prayer. CONCLUSION: Nurse religiosity and work environment were associated with nurse opinions about initiating spiritual/religious discourse with patients.

An in vitro evaluation of the maxillary occlusal plane orientation obtained with an electronic application: A preliminary investigation.

STATEMENT OF PROBLEM: In the evaluation and fabrication of dental prostheses, maxillary occlusal plane orientation in the sagittal and coronal planes may affect functional and esthetic outcomes. The accuracy of a recently developed electronic application in transferring this orientation to a semiadjustable articulator has not been evaluated. PURPOSE: The purpose of this in vitro study was to evaluate the coronal and sagittal orientation of the occlusal plane on maxillary casts mounted with an electronic application facebow system onto a corresponding semiadjustable arcon articulator. MATERIAL AND METHODS: A maxillary typodont was placed into a phantom head (control) oriented with the Frankfort horizontal plane parallel to the horizon. A digital protractor was used to measure the angle between the occlusal plane of the maxillary arch of the phantom head and the Frankfort horizontal plane along the sagittal and coronal planes. The commercial system (test group) was used to make 15 facebow records of the maxillary typodont within the phantom head. The system records were used to mount diagnostic casts of the maxillary typodont onto a semiadjustable arcon articulator. The same measurements were made on the mounted diagnostic casts and were compared with the control. Statistical differences between the occlusal plane of the control and the occlusal plane of the mounted maxillary casts were determined using the 1-sample t test (α=.05). RESULTS: The coronal orientation of the occlusal plane was significantly different (P<.001) between test group and control. No significant differences (P>.05) were found in the sagittal orientation of the occlusal plane. CONCLUSIONS: Within the limitations of this study, variations in the coronal plane orientation were observed with the system. Variations in this plane may lead to adverse evaluation and clinical outcomes.

A Meta-analysis of Outcomes Using Acellular Dermal Matrix in Breast and Abdominal Wall Reconstructions: Event Rates and Risk Factors Predictive of Complications.

BACKGROUND: The use of acellular dermal matrix (ADM) has gained acceptance in breast and abdominal wall reconstructions. Despite its extensive use, there is currently a wide variation of reported outcomes in the literature. This study definitively elucidates the outcome rates associated with ADM use in breast and abdominal wall surgeries and identifies risk factors predisposing to the development of complications. METHODS: A literature search was conducted using the Medline database (PubMed, US National Library of Medicine) and the Cochrane Library. A total of 464 articles were identified, of which 53 were eligible for meta-analysis. The endpoints of interest were the incidences of seroma, cellulitis, infection, wound dehiscence, implant failure, and hernia. The effects of various risk factors such as smoking, radiation, chemotherapy, and diabetes on the development of complications were also evaluated. RESULTS: A majority of the studies were retrospective (68.6%) with a mean follow-up of 16.8 months (SD ± 10.1 months) in the breast group and 14.2 months (SD ± 7.8 months) in the abdominal wall reconstructive group. The overall risks and complications were as follows: cellulitis, 5.1%; implant failure, 5.9%; seroma formation, 8%; wound dehiscence, 8.1%; wound infection, 16.1%; hernia, 27.6%; and abdominal bulging, 28.1%. Complication rates were further stratified separately for the breast and abdominal cohorts, and the data were reported. This provides additional information on the associated abdominal wall morbidity in patients undergoing autologous breast reconstruction in which mesh reinforcement was considered as closure of the abdominal wall donor site. Radiation resulted in a significant increase in the rates of cellulitis (P = 0.021), and chemotherapy was associated with a higher incidence of seroma (P = 0.014). CONCLUSION: This study evaluates the overall complication rates associated with ADM use by conducting a meta-analysis of published data. This will offer physicians a single comprehensive source of information during informed consent discussions as well as an awareness of the risk factors predictive of complications.

In vitro comparison of the maxillary occlusal plane orientation obtained with five facebow systems.

STATEMENT OF PROBLEM: The sagittal and coronal orientation of the maxillary occlusal plane plays an important role in the esthetic and functional outcome of dental prostheses. The accuracy of contemporary facebow transfer systems in transferring this orientation to semiadjustable articulators has not been quantified. PURPOSE: The purpose of this in vitro investigation was to analyze the sagittal and coronal orientation of the occlusal plane with 5 different facebow transfer systems. MATERIAL AND METHODS: A phantom head containing a maxillary typodont (control) was oriented so that the Frankfort horizontal plane was horizontal. The angle between the occlusal plane of the maxillary arch of the phantom head and the Frankfort horizontal plane was measured along the sagittal and coronal planes with a digital protractor. Fifteen facebow records using each of 5 facebow transfer systems (test groups) were made on the phantom head containing the maxillary typodont. Diagnostic casts of the maxillary typodont were mounted on semi-adjustable arcon articulators from the facebow records. The same angles measured on the control were measured on the test groups. These angles were compared with the same angle measured on the maxillary arch of the phantom head (control). All measurements were made by 2 operators. RESULTS: Significant differences in the sagittal and coronal orientation of the occlusal plane were noted. Compared with the control, the Denar system had the least significant difference in the coronal orientation of the occlusal plane, while the Pana-Mount system had the least significant difference in the sagittal orientation of the occlusal plane. An intergroup comparison of the test groups showed significant differences among the groups. The Kois system showed the greatest difference in the coronal plane orientation, while the Denar system showed the greatest difference in the sagittal plane orientation. CONCLUSIONS: None of the tested facebow systems exactly replicated the sagittal and coronal orientation of the maxillary occlusal plane. Significant differences in the sagittal and coronal orientation of the occlusal plane were observed between the test groups and the control. Intergroup comparisons revealed significant differences in the sagittal and coronal orientation of the occlusal plane.

The inter-rater reliability of clinical tests that best predict the subclassification of lumbar segmental instability: structural, functional and combined instability.

OBJECTIVES: This study investigated the inter-rater reliability of three structural end range lumbar segmental instability tests with the highest positive likelihood ratio (+ LR) against flexion-extension radiographs, and three functional mid-range clinical tests that predict the success of lumbar stabilisation exercises in patients with recurrent or chronic low-back pain (R/CLBP). The study also investigated the reliability of lumbar segmental instability, subclassification as: functional, structural and combined instability. METHOD: Forty adults with R/CLBP (30 men and 10 women), aged 21-71 years, underwent repeated measurements of specific clinical tests for structural or functional lumbar segmental instability. RESULTS: All functional-instability tests: the prone instability test (PIT), the aberrant motion test and the average passive straight-leg raise (PSLR>91°) test showed a high percentage agreement (90, 97·5 and 95%, respectively) and a high kappa coefficient (0·71, 0·79 and 0·77, respectively). In addition, two structural tests: the lumbar flexion range of motion (ROM) >53° and the passive lumbar extension test (PLET) showed a high percentage agreement (82 and 73%, respectively), and a moderate kappa coefficient (0·48 and 0·46, respectively). The lack of hypomobility with the posteroanterior (PA) glide test was found to be unreliable (agreement = 25%; k = - 0·02). Locating the pain-provoking segment, as the first portion of PIT, was found to be moderately reliable (k = 0·41). The subclassification categories of lumbar segmental instability (functional, structural and combined) were found to be significantly reliable (PABAK) 0·90, 0·70 and 0·95, respectively). DISCUSSION: All investigated tests (except the lack of hypomobility with the PA glide test), in addition to subclassifying the categories of lumbar segmental instability, were significantly reliable in the assessment of lumbar instability.

Analyzing Potential Interactions Between Complementary and Alternative Therapies, Over-the-Counter, and Prescription Medications in the Older Population.

BACKGROUND: The escalating use of complementary and alternative medicine (CAM) raises concerns, particularly among geriatric patients taking multiple medications. Notably, the doubled chance of major drug interactions between prescription and over-the-counter (OTC) drugs in older adults underscores the need for further research. This study aimed to evaluate clinically significant CAM and prescription medication interactions in a geriatric clinic, emphasizing the growing importance of understanding CAM implications in health care. METHODS: A 2-year cross-sectional study, approved by the Institutional Review Board, enrolled 420 participants aged 65 and older from a geriatric primary care clinic. Participants completed a survey, and pharmacy students conducted chart reviews to evaluate potential CAM products and prescription medication interactions. RESULTS: Among the 420 participants-who were predominantly White females and who were taking supplements, OTC medications, or both-15.6% experienced potential drug interactions. Ginkgo biloba, garlic, and calcium were common contributors to major, moderate, and minor interactions, respectively, among supplements. Meanwhile, ibuprofen was among the contributors to major and moderate interactions among OTC medications. Most supplements and OTC medications were disclosed to health care professionals. However, there was a lack of investigation by health care professionals regarding CAM use, emphasizing a discrepancy between patient-reported and physician-inquired CAM usage. CONCLUSION: This study highlighted the significant use of CAM and/or OTC medications, particularly among vulnerable older adults, revealing a concerning 15.6% rate of potential drug interactions. The findings emphasized the need for awareness among health care practitioners and standardized CAM surveys to enhance accuracy and patient safety.

Oral sucrose for heel lance increases adenosine triphosphate use and oxidative stress in preterm neonates.

OBJECTIVE: To examine the effects of sucrose on pain and biochemical markers of adenosine triphosphate (ATP) degradation and oxidative stress in preterm neonates experiencing a clinically required heel lance. STUDY DESIGN: Preterm neonates that met study criteria (n = 131) were randomized into 3 groups: (1) control; (2) heel lance treated with placebo and non-nutritive sucking; and (3) heel lance treated with sucrose and non-nutritive sucking. Plasma markers of ATP degradation (hypoxanthine, xanthine, and uric acid) and oxidative stress (allantoin) were measured before and after the heel lance. Pain was measured with the Premature Infant Pain Profile. Data were analyzed by the use of repeated-measures ANOVA and Spearman rho. RESULTS: We found significant increases in plasma hypoxanthine and uric acid over time in neonates who received sucrose. We also found a significant negative correlation between pain scores and plasma allantoin concentration in a subgroup of neonates who received sucrose. CONCLUSION: A single dose of oral sucrose, given before heel lance, significantly increased ATP use and oxidative stress in premature neonates. Because neonates are given multiple doses of sucrose per day, randomized trials are needed to examine the effects of repeated sucrose administration on ATP degradation, oxidative stress, and cell injury.

In vitro comparison of the tensile bond strength of denture adhesives on denture bases.

STATEMENT OF PROBLEM: With several denture adhesives available, it is important for dentists to make appropriate patient recommendations. PURPOSE: The purpose of this study was to evaluate the tensile bond strength of denture adhesives on denture base materials at time intervals of up to 24 hours. MATERIAL AND METHODS: Fixodent, Super Poligrip, Effergrip, and SeaBond denture adhesives were tested with 3 denture base materials: 2 heat-polymerized (Lucitone 199 and SR Ivocap) and 1 visible-light-polymerized (shade-stable Eclipse). Artificial saliva with mucin was used as a control. Tensile bond strength was tested in accordance with American Dental Association specifications at 5 minutes, 3 hours, 6 hours, 12 hours, and 24 hours after applying the adhesive. Maximum forces before failure were recorded in megapascals (MPa), and the data were subjected to a 2-way analysis of variance (α=.05). RESULTS: All 4 adhesives had greater tensile bond strength than the control. Fixodent, Super Poligrip, and SeaBond had higher tensile bond strength values than Effergrip. All adhesives had the greatest tensile bond strength at 5 minutes and the least at 24 hours. The 3 denture bases produced significantly different results with each adhesive (P<.001). Lucitone 199 with the adhesives had the greatest tensile bond strength, followed by Ivocap and Eclipse. CONCLUSIONS: All 4 adhesives had greater tensile bond strength than the control, and all 4 adhesives were strongest at the 5-minute interval. On all 3 types of denture bases, Effergrip produced significantly lower tensile bond strength, and Fixodent, Super Poligrip, and SeaBond produced significantly higher tensile bond strength. At 24 hours, the adhesive-base combinations with the highest tensile bond strength were Fixodent on Lucitone 199, Fixodent on Eclipse, Fixodent on Ivocap, and Super Poligrip on Ivocap.

Potential Association of Holidays on Internationalized Normalized Ratio in Warfarin-Users at a Multidisciplinary Clinic.

Background: Warfarin is approved by the United States Food and Drug Administration for numerous clinical indications. The effectiveness of warfarin is highly dependent on the time-in-therapeutic range based on the international normalized ratio (INR) goal, which may be altered by changes in diet, alcohol intake, concomitant drugs, and travel, all of which are prevalent during the holidays. At this time, there are no published studies assessing the impact of holidays on INR in warfarin-users. Methods: A retrospective chart review was conducted on all adult patients taking warfarin and managed at a multidisciplinary clinic. Patients were included if they were taking warfarin at home regardless of indication for anticoagulation. The INR pre- and post-holiday was assessed. Results: Of a total of 92 patients, the mean age was 71.5 ± 14.3 years, and most patients were on warfarin with an INR goal of 2 - 3 (89%). There were significant differences in INR before and after Independence Day (2.55 vs. 2.81, P = 0.043) and Columbus Day (2.39 vs. 2.82, P < 0.001). The remaining holidays showed no significant differences in INR before and after each respective holiday. Conclusions: There may be factors related to Independence and Columbus Day that are increasing the level of anticoagulation in warfarin-users. Although the mean post-holiday INR values, in essence, maintained within the typical target of 2 - 3, our study underscores the specialized care that is warranted in higher risk patients to prevent a continued increase in INR and subsequent toxicities. We hope our results would be hypothesis-generating and aid in the development of larger, prospective evaluations to validate the findings of our present study.

Ethanol Lock for Prevention of CVC-Related Bloodstream Infection in Pediatric Patients: A Systematic Review and Meta-Analysis.

Ethanol lock therapy (ELT) can be used in patients with an indwelling central line to assist in the prevention of central venous catheter (CVC)-associated infections. However, its efficacy has not been consistently demonstrated in the pediatric population. The primary objective of this review and meta-analysis was to determine the efficacy and safety of ELT in prevention of central line-associated bloodstream infection (CLABSI) in the pediatric population. A search was conducted with the PubMed, CINAHL, PSCYInfo, Cochrane Library, and Academic Search Premier databases from inception through January 21, 2022. Studies were included if they reported incidence of CVC-related infections with ELT in pediatric patients. Meta-analyses used random-effects models according to the heterogeneity of all included studies. Of 736 studies, 25 met inclusion criteria for review and 10 for inclusion in the meta-analysis. Meta-analysis with pre- and post-ELT treatment showed that use of ELT significantly decreased mean CVC-related infections when compared with pre-treatment with no ELT with a mean difference of -5.79 (95% CI, -9.08 to -2.51; p < 0.001). The number of CVC infections also significantly decreased (OR, 0.42; 95% CI, 0.23-0.75; p = 0.004). Increased risk of thrombosis and increased frequency of catheter breakage, repair, and replacement were noted in several studies. Ethanol lock therapy is effective in preventing infection related to central venous catheter use in pediatric patients. Further study is warranted to determine the optimal protocol for, and incidence of, adverse events related to use of ELT.

The effect of the COVID-19 pandemic on the prescribing of opioid and opioid use disorder medications within an academic medical center in California.

Introduction: The COVID-19 pandemic impacted healthcare operations affecting many patients with chronic pain and substance use disorder. Our study aimed to evaluate the effects of the COVID-19 pandemic on opioid and opioid use disorder (OUD) medication prescribing practices within a large academic health system in southern California. Methods: This retrospective cohort study included patients who received a prescription for chronic opioids or therapy for OUD between November 1, 2019 and September 1, 2020. The date range was divided into five specific time periods during the pandemic: November through December 2019 (pre-COVID and reference period), January through February 2020 (early COVID), March through April 2020 (policy/guidance change period), May through June 2020 (early post-guidance period), and July through August 2020 (late post-guidance period). The primary outcome was change in morphine milligram equivalents (MME) prescribed. Secondary outcomes included encounter type, mode of prescription ordering, naloxone prescriptions, and urine drug screen obtainment. Results: The cohort included 100 patients divided among the designated time periods. Seventy-percent of patients received opioids for chronic non-malignant pain and 10% received therapy for OUD. Although there were numerical increases in MMEs prescribed, no significant changes were seen in the MMEs prescribed at any timepoint relative to the pre-COVID timeframe despite reduced in-person visits, increased video and telephone encounters and increased electronic prescription utilization. Subgroup analyses of those with chronic pain only or OUD had similar findings. Conclusion: It appears that, generally, prescribing practices were sustained despite the various phases of the pandemic including transitions to and from telemedicine.

National survey of educational impact on pharmacy learners by volunteering at camps for children with diabetes.

INTRODUCTION: Current literature on pharmacy students' and residents' experience attending camps for children with diabetes focuses on the experience at an individual campsite. The objective of this study was to examine the demographics and gains in understanding that pharmacy learners achieve when volunteering as medical staff at camps for children with type 1 diabetes (T1D). METHODS: National listservs were used to identify pharmacists who precept pharmacy students and residents at diabetes camps. These self-identified pharmacists shared pre- and post-camp electronic surveys with their respective pharmacy learners. Statistical analysis was completed using SPSS Version 25 (IBM, Corp.). RESULTS: Eighty-six pharmacy learners completed the pre-camp survey and 69 completed the post-camp survey. Most were Caucasian, in their fourth professional year, and participated in residential camps that lasted six and one-half days on average. Learners consistently engaged in patient care activities including: carbohydrate counting (87%), bolus insulin dose calculations (86%), treatment of hypo/hyperglycemic episodes (86%), blood glucose testing (83%), blood sugar trend evaluation (78%), basal insulin dosing calculations (74%), and insulin pump site changes (72%). Learners demonstrated statistically significant gains in every index measured with the exception of glucometer use. Eighty-seven percent indicated they learned how to appropriately manage T1D, 37% gained empathy for those living with T1D, and 13% learned how to work in a medical team. CONCLUSIONS: Pharmacy learners who volunteered at diabetes camps experienced large gains in their understanding of concepts and devices, comfort with performing patient care tasks, and compassion for children and their families living with T1D.

Why Can't I Stop Smoking: Predictors of Tobacco Use and Quit Rates in the Freedom From Tobacco Program.

Introduction  As the leading cause of preventable chronic diseases in adults 18 years and older, tobacco usage in the U.S. results in over 20 million premature deaths annually. Current smokers might need extra support on the path to successfully quitting.  Aim To evaluate the influence of predictors of smoking-on-smoking cessation in the Freedom From Tobacco Program (FFT) offered by Southern California Permanente Medical Group (SCPMG). Methods This was a quasi-experimental study to evaluate rates of smoking cessation among participants in the FFT program. There were 471 participants in the study. Factors of the Social Ecological Model (SEM) and demographics were examined to determine if they could predict tobacco cessation. The SEM suggests that an individual's behavior is integrated into a network of intrapersonal characteristics, interpersonal processes, institutional factors, community features, and public policy. In particular, the study mainly addressed the institutional factor. It was promoted within a Health Management Organization and the interpersonal process because it was a group intervention.  Findings  After multiple regression analyses with all predictors from the SEM and demographics, the only significant predictor was the number of previous attempts to quit. Smokers who tried to stop four or more times in the past were 2.6 times (p<0.03) more likely to quit than those who tried fewer times. As we are aware, this was the first time this result was found for programs implemented by Health Management Organizations. The general quit rate at 12 months for the FFT program was 43.1%. Conclusion As the only predictor of quitting in this study was the number of previous attempts to quit smoking, the recommendation is to develop longer-term smoking cessation programs or a longer follow-up to facilitate smokers who relapse to go back and try to quit again. Another recommendation is to identify the main reasons for relapse and try to address these factors in further interventions.

Knowledge, Attitude, and Psychological Impacts of COVID-19 in Saudi Arabia.

Background: The world has been facing an unprecedented pandemic of COVID-19 with over 336 million people infected and millions of deaths. This required an enormous communication effort response from governments, international, and individuals to keep the public informed about the outbreak. When a pandemic affects communities, individuals' knowledge and attitude are important factors to contain the outbreak. Thus, the purpose of this study is to measure individuals' knowledge and attitude toward COVID-19 and ascertain whether a need exists for mental health services for those who were affected by the pandemic. Methods: A cross-sectional design was used to measure the knowledge, attitude, and psychological impacts about the COVID-19 pandemic among the Saudi population. Research participants were recruited using a snowball sampling technique through the social media platform WhatsApp. A total of 482 eligible individuals participated from various locations in Saudi Arabia represented almost all Saudi regions. The questionnaire consisted of seven questions evaluating knowledge, seven gauging attitudes, and 16 questions assessing anxiety and perceived need for mental healthcare services. Results: A modest level of knowledge (59%) was found among the Saudi population sampled about the COVID-19 pandemic, and satisfactory knowledge (>80%) about its preventive measures. Anxiety and stress existed among the participants (79% obsessed with COVID-19), with an 88% approval rate for obtaining mental health services for individuals highly affected by the pandemic. Conclusion: There is a need to increase awareness and provide continuous updates regarding the pandemic situation. Promoting access to mental health services is critical, as well as finding creative and suitable strategies to deliver mental health services to those who need them.

Student perception of academic advising in a school of pharmacy.

OBJECTIVES: Literature assessing the optimal means of providing academic advisement in pharmacy education is limited. The objective of this study was to describe students' perception of advising within a school of pharmacy. METHODS: A 27-question survey was developed utilizing Qualtrics and sent to all students at one school of pharmacy. Baseline descriptive data regarding frequency and format of meeting with the assigned advisor were collected, as well as students' opinions of these meetings. KEY FINDINGS: Of 282 students who were sent the survey, 90 responded (31.9%). The majority of students preferred to meet with their faculty advisor in a group as compared with one-on-one (59 versus 29, 67%). Most students found the advisor/advisee relationship beneficial (n = 77, 85%). CONCLUSIONS: There was no statistically significant difference in student perception of the quality or value of advisor/advisee meetings between students who met in a group or one-on-one with their advisors.