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1.

Entirely noninvasive outcome prediction in central nervous system lymphomas using circulating tumor DNA.

Heger, Jan-Michel; Mattlener, Julia; Schneider, Jessica; Gödel, Philipp; Sieg, Noëlle; Ullrich, Fabian; Lewis, Richard; Bucaciuc-Mracica, Teodora; Schwarz, Roland F; Rueß, Daniel; Ruge, Maximilian I; Montesinos-Rongen, Manuel; Deckert, Martina; Blau, Tobias; Kutsch, Nadine; Balke-Want, Hyatt; Weiss, Jonathan; Becker, Kerstin; Reinhardt, H Christian; Hallek, Michael; Borchmann, Peter; von Tresckow, Bastian; Borchmann, Sven.

Blood ; 143(6): 522-534, 2024 Feb 08.

Artículo en Inglés | MEDLINE | ID: mdl-37946299

2.

Noninvasive minimal residual disease assessment in relapsed/refractory large B-cell lymphoma using digital droplet PCR.

Heger, Jan-Michel; d'Hargues, Yannick; Kleinert, Fanni; Mattlener, Julia; Weiss, Jonathan; Franzen, Fabian; Becker, Christian; Becker, Kerstin; Gödel, Philipp; Schmiel, Marcel; Meinel, Jörn; Flümann, Ruth; Simon, Florian; Reinhardt, H Christian; Borchmann, Peter; Borchmann, Sven; Balke-Want, Hyatt; Knittel, Gero; von Tresckow, Bastian.

Eur J Haematol ; 112(6): 957-963, 2024 Jun.

Artículo en Inglés | MEDLINE | ID: mdl-38369814

3.

Homology-independent targeted insertion (HITI) enables guided CAR knock-in and efficient clinical scale CAR-T cell manufacturing.

Balke-Want, Hyatt; Keerthi, Vimal; Gkitsas, Nikolaos; Mancini, Andrew G; Kurgan, Gavin L; Fowler, Carley; Xu, Peng; Liu, Xikun; Asano, Kyle; Patel, Sunny; Fisher, Christopher J; Brown, Annie K; Tunuguntla, Ramya H; Patel, Shabnum; Sotillo, Elena; Mackall, Crystal L; Feldman, Steven A.

Mol Cancer ; 22(1): 100, 2023 06 26.

Artículo en Inglés | MEDLINE | ID: mdl-37365642

4.

Impact of timing and precision of histopathological diagnosis on outcomes of patients with Burkitt lymphoma and high-grade B-cell lymphoma.

Graef, Claus Moritz; Gödel, Philipp; Falderbaum, Philipp; Balke-Want, Hyatt; Simon, Florian; Sieg, Noëlle; Naendrup, Jan-Hendrik; Neumann, Marie Anne-Catherine; Gillessen, Sarah; Bröckelmann, Paul J; Eichenauer, Dennis A; Borchmann, Peter; von Tresckow, Bastian; Heger, Jan-Michel.

Eur J Haematol ; 108(5): 403-412, 2022 May.

Artículo en Inglés | MEDLINE | ID: mdl-35090068

5.

Treatment patterns and disease course of previously untreated Primary Central Nervous System Lymphoma: Feasibility of MTX-based regimens in clinical routine.

Sieg, Noëlle; Naendrup, Jan-Hendrik; Gödel, Philipp; Balke-Want, Hyatt; Simon, Florian; Deckert, Martina; Gillessen, Sarah; Kreissl, Stefanie; Bröckelmann, Paul J; Borchmann, Peter; von Tresckow, Bastian; Heger, Jan-Michel.

Eur J Haematol ; 107(2): 202-210, 2021 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-33960535

6.

Putting the pedal to the metal: axi-cel for LBCL.

Balke-Want, Hyatt.

Blood ; 141(19): 2285-2286, 2023 05 11.

Artículo en Inglés | MEDLINE | ID: mdl-37166931

7.

A framework for identification of actionable cancer genome dependencies in small cell lung cancer.

Sos, Martin L; Dietlein, Felix; Peifer, Martin; Schöttle, Jakob; Balke-Want, Hyatt; Müller, Christian; Koker, Mirjam; Richters, André; Heynck, Stefanie; Malchers, Florian; Heuckmann, Johannes M; Seidel, Danila; Eyers, Patrick A; Ullrich, Roland T; Antonchick, Andrey P; Vintonyak, Viktor V; Schneider, Peter M; Ninomiya, Takashi; Waldmann, Herbert; Büttner, Reinhard; Rauh, Daniel; Heukamp, Lukas C; Thomas, Roman K.

Proc Natl Acad Sci U S A ; 109(42): 17034-9, 2012 Oct 16.

Artículo en Inglés | MEDLINE | ID: mdl-23035247

8.

An anti-CD19/CTLA-4 switch improves efficacy and selectivity of CAR T cells targeting CD80/86-upregulated DLBCL.

Prinz, Lars Fabian; Riet, Tobias; Neureuther, Daniel Felix; Lennartz, Simon; Chrobok, Danuta; Hübbe, Hanna; Uhl, Gregor; Riet, Nicole; Hofmann, Petra; Hösel, Marianna; Simon, Adrian Georg; Tetenborg, Luis; Segbers, Paul; Shimono, Joji; Gödel, Philipp; Balke-Want, Hyatt; Flümann, Ruth; Knittel, Gero; Reinhardt, Hans Christian; Scheid, Christoph; Büttner, Reinhard; Chapuy, Björn; Ullrich, Roland Tillmann; Hallek, Michael; Chmielewski, Markus Martin.

Cell Rep Med ; 5(2): 101421, 2024 Feb 20.

Artículo en Inglés | MEDLINE | ID: mdl-38340727

9.

Dissecting intratumour heterogeneity of nodal B-cell lymphomas at the transcriptional, genetic and drug-response levels.

Roider, Tobias; Seufert, Julian; Uvarovskii, Alexey; Frauhammer, Felix; Bordas, Marie; Abedpour, Nima; Stolarczyk, Marta; Mallm, Jan-Philipp; Herbst, Sophie A; Bruch, Peter-Martin; Balke-Want, Hyatt; Hundemer, Michael; Rippe, Karsten; Goeppert, Benjamin; Seiffert, Martina; Brors, Benedikt; Mechtersheimer, Gunhild; Zenz, Thorsten; Peifer, Martin; Chapuy, Björn; Schlesner, Matthias; Müller-Tidow, Carsten; Fröhling, Stefan; Huber, Wolfgang; Anders, Simon; Dietrich, Sascha.

Nat Cell Biol ; 22(7): 896-906, 2020 07.

Artículo en Inglés | MEDLINE | ID: mdl-32541878

10.

Systematic Kinase Inhibitor Profiling Identifies CDK9 as a Synthetic Lethal Target in NUT Midline Carcinoma.

Brägelmann, Johannes; Dammert, Marcel A; Dietlein, Felix; Heuckmann, Johannes M; Choidas, Axel; Böhm, Stefanie; Richters, André; Basu, Debjit; Tischler, Verena; Lorenz, Carina; Habenberger, Peter; Fang, Zhizhou; Ortiz-Cuaran, Sandra; Leenders, Frauke; Eickhoff, Jan; Koch, Uwe; Getlik, Matthäus; Termathe, Martin; Sallouh, Muhammad; Greff, Zoltán; Varga, Zoltán; Balke-Want, Hyatt; French, Christopher A; Peifer, Martin; Reinhardt, H Christian; Örfi, László; Kéri, György; Ansén, Sascha; Heukamp, Lukas C; Büttner, Reinhard; Rauh, Daniel; Klebl, Bert M; Thomas, Roman K; Sos, Martin L.

Cell Rep ; 20(12): 2833-2845, 2017 Sep 19.

Artículo en Inglés | MEDLINE | ID: mdl-28930680

11.

Identification and further development of potent TBK1 inhibitors.

Richters, André; Basu, Debjit; Engel, Julian; Ercanoglu, Meryem S; Balke-Want, Hyatt; Tesch, Roberta; Thomas, Roman K; Rauh, Daniel.

ACS Chem Biol ; 10(1): 289-98, 2015 Jan 16.

Artículo en Inglés | MEDLINE | ID: mdl-25540906

12.

Differential protein stability and ALK inhibitor sensitivity of EML4-ALK fusion variants.

Heuckmann, Johannes M; Balke-Want, Hyatt; Malchers, Florian; Peifer, Martin; Sos, Martin L; Koker, Mirjam; Meder, Lydia; Lovly, Christine M; Heukamp, Lukas C; Pao, William; Küppers, Ralf; Thomas, Roman K.

Clin Cancer Res ; 18(17): 4682-90, 2012 Sep 01.

Artículo en Inglés | MEDLINE | ID: mdl-22912387

13.

ALK mutations conferring differential resistance to structurally diverse ALK inhibitors.

Heuckmann, Johannes M; Hölzel, Michael; Sos, Martin L; Heynck, Stefanie; Balke-Want, Hyatt; Koker, Mirjam; Peifer, Martin; Weiss, Jonathan; Lovly, Christine M; Grütter, Christian; Rauh, Daniel; Pao, William; Thomas, Roman K.

Clin Cancer Res ; 17(23): 7394-401, 2011 Dec 01.

Artículo en Inglés | MEDLINE | ID: mdl-21948233

14.

Frequent and focal FGFR1 amplification associates with therapeutically tractable FGFR1 dependency in squamous cell lung cancer.

Weiss, Jonathan; Sos, Martin L; Seidel, Danila; Peifer, Martin; Zander, Thomas; Heuckmann, Johannes M; Ullrich, Roland T; Menon, Roopika; Maier, Sebastian; Soltermann, Alex; Moch, Holger; Wagener, Patrick; Fischer, Florian; Heynck, Stefanie; Koker, Mirjam; Schöttle, Jakob; Leenders, Frauke; Gabler, Franziska; Dabow, Ines; Querings, Silvia; Heukamp, Lukas C; Balke-Want, Hyatt; Ansén, Sascha; Rauh, Daniel; Baessmann, Ingelore; Altmüller, Janine; Wainer, Zoe; Conron, Matthew; Wright, Gavin; Russell, Prudence; Solomon, Ben; Brambilla, Elisabeth; Brambilla, Christian; Lorimier, Philippe; Sollberg, Steinar; Brustugun, Odd Terje; Engel-Riedel, Walburga; Ludwig, Corinna; Petersen, Iver; Sänger, Jörg; Clement, Joachim; Groen, Harry; Timens, Wim; Sietsma, Hannie; Thunnissen, Erik; Smit, Egbert; Heideman, Daniëlle; Cappuzzo, Federico; Ligorio, Claudia; Damiani, Stefania.

Sci Transl Med ; 2(62): 62ra93, 2010 Dec 15.

Artículo en Inglés | MEDLINE | ID: mdl-21160078

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