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1.
BMC Public Health ; 24(1): 15, 2024 01 02.
Artículo en Inglés | MEDLINE | ID: mdl-38167012

RESUMEN

Young adults (18-24 years) in universities are frequently exposed to an environment that promotes unhealthy eating behaviors. Using a validated tool, the Chinese Nutrition Environment Measurement Survey for Stores (C-NEMS-S), we assess the food availability and healthier options in a large, urban Chinese university. We employed C-NEMS-S for scoring criteria and weighting. A total of 52 on-campus canteen outlets were audited in an urban university located in Shijiazhuang City, China. General food outlets (n 43) and self-served food outlets (n 7) were further categorized into eight subtypes. Beverage outlets (n 2) were discussed separately from food outlets. C-NEMS-S scores were significantly different across food outlet types (P = 0.0024), especially between noodle and rice outlets (P = 0.0415). Food availability scores for starchy tubers (P < 0.001), dry beans (P < 0.001), vegetables (P = 0.0225), and fruits (P < 0.001) were significantly different across food outlet subtypes. Healthier options were scarce and only appeared in "grains" (n 2) and "meat and poultry" (n 2) categories. Further research on improving the accustomed audit tool and assessing university student diet quality is warranted.


Asunto(s)
Dieta , Estado de Salud , Adulto Joven , Humanos , Universidades , Encuestas Nutricionales , Verduras , Abastecimiento de Alimentos , Comercio
2.
Eur J Appl Physiol ; 124(1): 343-352, 2024 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-37517068

RESUMEN

PURPOSE: Polluted environments can adversely affect lung function and exercise performance. Evidence suggests that some nutrient supplements may offset pollution's detrimental effects. This study examined the effect of polyphenol supplementation on lung function and exercise performance in an ozone-polluted environment. METHODS: Ten male cyclists (mean ± SD: age, 43.8 ± 12.4 years; height, 177.8 ± 7.1 cm; weight, 76.03 ± 7.88 kg; VO2max 4.12 ± 0.72 L min-1) initially completed a baseline maximal incremental test and maximal effort 4 km time trial in ambient air. Thereafter cyclists completed two trials in an ozone-polluted environment (0.25 ppm) following seven days of supplementation with either polyphenol (PB) or placebo (PL). Experimental trials consisted of a three-stage submaximal test (50%, 60% and 70% incremental peak power) followed by a 4 km time trial. Lung function was measured pre- and post-exercise via spirometry and adverse respiratory symptoms with a Likert scale. RESULTS: Ozone exposure significantly reduced (p < 0.05) lung function relative to ambient air. There were no significant differences (p > 0.05) in measured variables across the three submaximal intensities. There was a small (d = 0.31) non-significant difference (p = 0.09) in 4 km performance in PB (406.43 ± 50.29 s) vs. PL (426.20 ± 75.06 s). Oxygen consumption during the time trial was greater in PB (3.49 ± 0.71 L min-1) vs PL (3.32 ± 0.71 L min-1, p = 0.01, d = 0.24). Cough severity (SOC) was lower (p = 0.03) with PB relative to PL. CONCLUSION: PB supplementation may provide small benefits to performance and reduce cough symptoms during high-intensity exercise in ozone-polluted environments.


Asunto(s)
Rendimiento Atlético , Ozono , Adulto , Humanos , Masculino , Persona de Mediana Edad , Ciclismo , Tos/inducido químicamente , Suplementos Dietéticos , Pulmón , Consumo de Oxígeno , Ozono/efectos adversos , Polvos
3.
BMC Geriatr ; 22(1): 905, 2022 11 25.
Artículo en Inglés | MEDLINE | ID: mdl-36434542

RESUMEN

BACKGROUND: As a result of the high prevalence of dysphagia in aged care facilities, demand for pureed diets is increasing. One of the biggest challenges for pureed diets is the reduced nutritional density due to the cooking process, such as when blending or softening with liquid. This study aimed to investigate the impact of innovative energy and protein-enriched meat puree on the nutrition intake and nutritional status of aged care residents requiring pureed diets. METHODS: This is a single-blinded randomised controlled trial conducted in two aged care facilities using a crossover design. Twenty-two residents aged 83.2 ± 7.3 years participated in a 12-week study. Participants were blocked randomised into two groups and received a 6-week of either control (unaltered freshly made pureed diets by facilities) or intervention diet, followed by a 2-week washout and then 6-week of alternative treatment. During the intervention, freshly made meat pureed portions were swapped to hydrolysed meat, which contained 144 -392 kcal and 5.6-6.8 g more energy and protein per 100 g. Nutrition intake was collected using a validated visual estimation method over 24 h on two non-consecutive days during the control and intervention phases. A two-tailed t-test was used to compare the significance. RESULTS: The intervention diet significantly increased energy (147 ± 285 kcal, p = .02), protein (4 ± 7 g, p = .04), and fat (3 ± 8 g, p = .07) intake in comparison to the control diet. Nutritional status was improved by the end of the intervention as evidenced by a higher nutritional assessment score using Mini-Nutritional Assessment - Short Form (9.1 ± 1.8) and a weight gain of 1.3 ± 1.7 g, p = .04. No significant differences were found in body composition using bioelectrical impedance analysis, calf circumference and mid-upper arm circumference. Though handgrip strength did not differ at the end of control and intervention, significance was found between the changes in control and intervention period. Plasma branched-chain amino acid increased significantly with hydrolysed meat consumption. CONCLUSIONS: As a dietary enrichment, hydrolysed meat is a promising intervention for pureed diet consumers in aged care facilities, improving residents' dietary intake and reducing malnutrition risk. Future larger multicentre studies with longer intervention periods are required to confirm the effectiveness and residents' acceptance. TRIAL REGISTRATION: Australian New Zealand Clinical Trials Registry (ACTRN12622000888763).


Asunto(s)
Fuerza de la Mano , Estado Nutricional , Humanos , Estudios Cruzados , Ingestión de Energía , Australia , Ingestión de Alimentos , Carne , Dieta
4.
Dysphagia ; 37(5): 1314-1325, 2022 10.
Artículo en Inglés | MEDLINE | ID: mdl-34993611

RESUMEN

Texture-modified diets (TMDs) are commonly prescribed for older adults with swallowing difficulties to improve swallowing safety. The International Dysphagia Diet Standardization Initiative (IDDSI) provides a framework for terminology, definitions and testing of TMDs. This observational mixed-method study used the consolidated framework for implementation research (CFIR) to establish the barriers and enablers to IDDSI adoption in aged-care facilities (ACFs). Five New Zealand ACFs who had adopted IDDSI > 12 months previously were recruited. Evaluation tools were developed based on CFIR constructs, integrating data from (i) mealtime observations; (ii) manager interviews and (iii) staff (nursing, carers and kitchen) self-administrated surveys. All facility and kitchen managers were IDDSI aware and had access to online resources. Three sites had changed to commercially compliant products post-IDDSI adoption, which had cost implications. Awareness of IDDSI amongst staff ranged from 5 to 79% and < 50% of staff surveyed felt sufficiently trained. Awareness was greater in large sites and where IDDSI was mandated by head office. Managers had not mandated auditing and they felt this had led to reduced perceived importance. Managers felt staff required more training and staff wanted more training, believing it would improve food safety and quality of care. Lack of a dedicated project leader and no speech pathologist on-site were perceived barriers. Collaboration between healthcare assistants, kitchen staff and allied health assisted implementation. ACF staff were aware of IDDSI but staff awareness was low. Using the CFIR, site specific and generic barriers and enablers were identified to improve future implementation effectiveness. Managers and staff want access to regular training. Multidisciplinary collaboration and improving communication are essential. ACFs should consider TMD auditing regularly. Successful implementation of IDDSI allows improvement of quality of care and patient safety but requires a systematic, site-specific implementation plan.


Asunto(s)
Trastornos de Deglución , Anciano , Deglución , Dieta , Humanos , Comidas , Estándares de Referencia
5.
Int J Sport Nutr Exerc Metab ; 32(6): 462-467, 2022 Nov 01.
Artículo en Inglés | MEDLINE | ID: mdl-35981712

RESUMEN

Blackcurrant juices and extracts containing anthocyanin may provide ergogenic benefits to sports performance. However, there are no studies examining the effects of coingestion of blackcurrant and caffeine. This investigation examined the effects of acute supplementation with a proprietary blackcurrant beverage administered in isolation or in combination with caffeine on repeated high-intensity cycling. Twelve well-trained male cyclists (mean ± SD: age, 39.5 ± 11.4 years; height, 177.9 ± 5.7 cm; weight, 78.2 ± 8.9 kg; and peak oxygen consumption, 4.71 ± 0.61 L/min) completed experimental sessions consisting of repeated (8 × 5 min) maximal intensity efforts. Four experimental treatments were administered in a double-blind, balanced Latin square design: blackcurrant + caffeine, blackcurrant + placebo, caffeine + placebo and placebo + placebo. Differences in power output, heart rate, oxygen consumption, muscle oxygen saturation, rate of perceived exertion, and cognitive function (Stroop) were compared between treatments using two-way repeated-measures analysis of variance and effect size analysis. There were no significant differences (p > .05) in either physiological or cognitive variables with any supplement treatment (blackcurrant + caffeine, blackcurrant + placebo, and caffeine + placebo) relative to placebo + placebo. Moreover, any observed differences were deemed trivial (d < 0.2) in magnitude. However, power output was lower (p < .05) in blackcurrant + placebo compared with blackcurrant + caffeine. A blackcurrant extract beverage administered in isolation or combination with caffeine provided no beneficial effect on cycling performance or physiological measures relative to a placebo control.


Asunto(s)
Rendimiento Atlético , Ribes , Masculino , Humanos , Adulto , Persona de Mediana Edad , Cafeína , Antocianinas/farmacología , Ciclismo/fisiología , Rendimiento Atlético/fisiología , Método Doble Ciego , Extractos Vegetales/farmacología , Estudios Cruzados
6.
Scand J Med Sci Sports ; 31(1): 140-152, 2021 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-32969535

RESUMEN

This study examined the effect of short-term adaptation to a ketogenic diet (KD) on resting and post-exercise immune markers. Using a randomized, repeated-measures, crossover design, eight trained, male, endurance athletes ingested a 31-day low carbohydrate (CHO), KD (energy intake: 4% CHO; 78% fat) or their habitual diet (HD) (energy intake: 43% CHO; 38% fat). On days 0 and 31, participants ran to exhaustion at 70% VO2max . A high-CHO (2 g·kg-1 ) meal was ingested prior to the pre-HD, post-HD, and pre-KD trials, with CHO (~55 g·h-1 ) ingested during exercise, whereas a low-CHO (<10 g) meal was ingested prior to the post-KD trial, with fat ingested during exercise. Blood and saliva samples were collected at pre-exercise, exhaustion, and 1 hour post-exhaustion. T-cell-related cytokine gene expression within peripheral blood mononuclear cells (PBMCs) and whole-blood inflammatory cytokine production were determined using 24-hour multi-antigen-stimulated whole-blood cultures. Multi-antigen-stimulated PBMC IFN-γ mRNA expression and the IFN-γ/IL-4 mRNA expression ratio were higher at exhaustion in the post-KD compared with pre-KD trial (P = 0.003 and P = 0.004); however, IL-4 and IL-10 mRNA expression were unaltered (P > 0.05). Multi-antigen-stimulated whole-blood IL-10 production was higher in the post-KD compared with pre-KD trial (P = 0.028), whereas IL-1ß, IL-2, IL-8, and IFN-γ production was lower in the post-HD compared with pre-HD trial (P < 0.01). Salivary immunoglobulin A (SIgA) secretion rate was higher in the post-KD compared with pre-KD trial (P < 0.001). In conclusion, short-term adaptation to a KD in endurance athletes may alter the pro- and anti-inflammatory immune cell cytokine response to a multi-antigen in vitro and SIgA secretion rate.


Asunto(s)
Inmunidad Adaptativa , Dieta Cetogénica , Inmunidad Mucosa , Resistencia Física/inmunología , Ácido 3-Hidroxibutírico/sangre , Biomarcadores/sangre , Glucemia/metabolismo , Estudios Cruzados , Citocinas/sangre , Expresión Génica , Humanos , Hidrocortisona/sangre , Inmunoglobulina A/metabolismo , Interferón gamma/genética , Interleucina-10/genética , Interleucina-4/genética , Leucocitos Mononucleares/inmunología , Masculino , ARN Mensajero/genética , Saliva/inmunología
7.
Eur J Appl Physiol ; 120(1): 191-202, 2020 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-31729600

RESUMEN

PURPOSE: We investigated the effect of the racemic ß-hydroxybutyrate precursor, R,S-1,3-butanediol (BD), on T-cell-related cytokine gene expression within stimulated peripheral blood mononuclear cells (PBMC) following prolonged, strenuous exercise. METHODS: A repeated-measures, randomised, crossover study was conducted in nine healthy, trained male cyclists (age, 26.7 ± 5.2 years; VO2peak, 63.9 ± 2.5 mL kg-1 min-1). Participants ingested 0.35 g kg-1 of BD or placebo 30 min before and 60 min during 85 min of steady-state (SS) exercise, which preceded a ~ 30 min time-trial (TT) (7 kJ kg-1). Blood samples were collected at pre-supplement, pre-exercise, post-SS, post-TT and 1-h post-TT. Whole blood cultures were stimulated with Staphylococcal enterotoxin B (SEB) for 24 h to determine T-cell-related interleukin (IL)-4, IL-10 and interferon (IFN)-γ mRNA expression within isolated PBMCs in vitro. RESULTS: Serum cortisol, total circulating leukocyte and lymphocyte, and T-cell subset concentrations were similar between trials during exercise and recovery (all p > 0.05). BD ingestion increased T-cell-related IFN-γ mRNA expression compared with placebo throughout exercise and recovery (p = 0.011); however, IL-4 and IL-10 mRNA expression and the IFN-γ/IL-4 mRNA expression ratio were unaltered (all p > 0.05). CONCLUSION: Acute hyperketonaemia appears to transiently amplify the initiation of the pro-inflammatory T-cell-related IFN-γ response to an immune challenge in vitro during and following prolonged, strenuous exercise; suggesting enhanced type-1 T-cell immunity at the gene level.


Asunto(s)
Citocinas/metabolismo , Cetosis/sangre , Acondicionamiento Físico Humano/métodos , Linfocitos T/inmunología , Adulto , Butileno Glicoles/farmacología , Citocinas/genética , Enterotoxinas/farmacología , Humanos , Cetosis/etiología , Masculino , Monocitos/metabolismo , Linfocitos T/efectos de los fármacos
8.
Health Promot Int ; 35(5): 892-906, 2020 Oct 01.
Artículo en Inglés | MEDLINE | ID: mdl-31504507

RESUMEN

Workplace wellness programmes have increased over the past years, but as yet has not been investigated in food and grocery organizations in New Zealand (NZ). The study aim was to explore the commitment of NZ Food and Grocery Council (FGC) companies in altering the workplace environment for employee health and the efficacy of the current wellness policies. Using a mixed-methods approach, FGC companies (n = 22) completed a workplace environment audit (WEA) survey. Three focus groups were held, consisting of employees (n = 20) from four of the FGC companies that completed the WEA survey. Two sets of data were then compared via methodological triangulation. The mean WEA score was 46% (p = 0.00), indicating an 'average' commitment by the FGC to health-promotion in their own workplaces. Significantly more initiatives related to improving nutrition were offered (p = 0.00) and larger food companies scored higher than smaller companies (p = 0.063). During the focus groups, employees revealed they felt workplace wellness programmes increased productivity, improved their physical health, allowed work-life balance, promoted social interaction and provided health-related education. Barriers to participating in wellness activities were identified as lack of time, working in a blue-collar position and working externally to the main office. The results of this study have large implications for companies and employers in NZ for future planning, implementation and monitoring of health initiatives in the workplace.


Asunto(s)
Salud Laboral , Lugar de Trabajo , Industria de Alimentos , Promoción de la Salud , Humanos , Nueva Zelanda
9.
Clin Exp Ophthalmol ; 47(1): 106-127, 2019 01.
Artículo en Inglés | MEDLINE | ID: mdl-29927057

RESUMEN

A systematic literature review was conducted to evaluate the role of diet and food intake in age-related macular degeneration (AMD). Eighteen high-quality studies were identified. Adherence to a Mediterranean diet had decreased risk of AMD progression. An Oriental diet pattern had decreased association with AMD prevalence, whereas a Western diet pattern had increased association with AMD prevalence. High consumption of vegetables rich in carotenoids and fatty fish containing omega-3 fatty acids was beneficial for those at risk of AMD. Vegetable oils and animal fats containing omega-6 fatty acids, and red/processed meat should be consumed minimally to reduce the risk of AMD progression. High glycaemic index diets and alcohol consumption of greater than two drinks a day had increased association with AMD. As the quality of diet and food intake had a vital role in AMD, the provision of appropriate nutritional advice to those at risk of AMD is recommended.


Asunto(s)
Dieta/métodos , Ingestión de Alimentos/fisiología , Degeneración Macular/terapia , Progresión de la Enfermedad , Humanos
10.
Int J Sport Nutr Exerc Metab ; 29(4): 364­370, 2019 07 01.
Artículo en Inglés | MEDLINE | ID: mdl-30160556

RESUMEN

Social media contains a wealth of nutrition information and proposes a cost-effective, highly engaging platform to deliver nutrition information to athletes. This study used an online questionnaire to determine whether New Zealand athletes are using social media as a source of nutrition information and to understand perceptions of social media as a nutrition resource. Quantitative data were analyzed using t tests, chi-squared tests, and logistic regression analysis. Inductive thematic analysis was adopted for the qualitative data. From the 306 athletes who completed the questionnaire, 65% reported social media use for nutrition purposes in the past 12 months. Social media use was predicted by both athlete status and gender. Female athletes were more likely to have used social media for nutrition purposes (odds ratio = 2.7, 95% confidence interval [1.52, 4.62], p = .001) than males. Elite athletes were less likely to have used social media for nutrition (odds ratio = 0.44, 95% confidence interval [0.24, 0.83], p = .011) than recreational athletes. Athletes commonly used social media for practical nutrition purposes, including recipes and information about restaurants/cafes. Perceived advantages of social media as a nutrition resource included ease of access, well-presented information, personal connectedness, and information richness. Athletes' primary concern for obtaining nutrition information from social media was information unreliability.


Asunto(s)
Atletas , Dieta Saludable , Conducta en la Búsqueda de Información , Medios de Comunicación Sociales , Adulto , Estudios Transversales , Femenino , Humanos , Masculino , Nueva Zelanda , Encuestas y Cuestionarios , Adulto Joven
11.
Int J Sport Nutr Exerc Metab ; 29(5): 466-473, 2019 Sep 01.
Artículo en Inglés | MEDLINE | ID: mdl-30632425

RESUMEN

This study investigated the effect of the racemic ß-hydroxybutyrate (ßHB) precursor, R,S-1,3-butanediol (BD), on time-trial (TT) performance and tolerability. A repeated-measures, randomized, crossover study was conducted in nine trained male cyclists (age, 26.7 ± 5.2 years; body mass, 69.6 ± 8.4 kg; height, 1.82 ± 0.09 m; body mass index, 21.2 ± 1.5 kg/m2; VO2peak,63.9 ± 2.5 ml·kg-1·min-1; Wmax, 389.3 ± 50.4 W). Participants ingested 0.35 g/kg of BD or placebo 30 min before and 60 min during 85 min of steady-state exercise, which preceded a ∼25- to 35-min TT (i.e., 7 kJ/kg). The ingestion of BD increased blood D-ßHB concentration throughout exercise (0.44-0.79 mmol/L) compared with placebo (0.11-0.16 mmol/L; all p < .001), which peaked 1 hr following the TT (1.38 ± 0.35 vs. 0.34 ± 0.24 mmol/L; p < .001). Serum glucose and blood lactate concentrations were not different between trials (all p > .05). BD ingestion increased oxygen consumption and carbon dioxide production after 20 min of steady-state exercise (p = .002 and p = .032, respectively); however, no further effects on cardiorespiratory parameters were observed. Within the BD trial, moderate to severe gastrointestinal symptoms were reported in five participants, and low levels of dizziness, nausea, and euphoria were reported in two participants. However, this had no effect on TT duration (placebo, 28.5 ± 3.6 min; BD, 28.7 ± 3.2 min; p = .62) and average power output (placebo, 290.1 ± 53.7 W; BD, 286.4 ± 45.9 W; p = .50). These results suggest that BD has no benefit for endurance performance.


Asunto(s)
Rendimiento Atlético/fisiología , Ciclismo/fisiología , Butileno Glicoles/administración & dosificación , Ácido 3-Hidroxibutírico/sangre , Adulto , Glucemia/análisis , Estudios Cruzados , Humanos , Ácido Láctico/sangre , Masculino , Consumo de Oxígeno , Sustancias para Mejorar el Rendimiento/administración & dosificación , Adulto Joven
12.
Cytokine ; 104: 136-142, 2018 04.
Artículo en Inglés | MEDLINE | ID: mdl-29021092

RESUMEN

Strenuous exercise bouts and heavy training are associated with a heightened anti-inflammatory state and a transient suppression of several immune components. In turn, many athletes are susceptible to illness, particularly upper respiratory symptoms (e.g. cough, sore throat, running nose). T-lymphocytes (T-cells) are important for orchestrating the immune response and can be categorised into subsets according to their phenotypical characteristics resulting from polarisation (i.e. type-1, type-2 and regulatory T-cells). Each T-cell subset has a unique functional role, including their capacity to produce pro- and anti-inflammatory cytokines in response to an immune challenge. Prolonged and exhaustive exercise typically reduces peripheral blood type-1 T-cell number and their capacity to produce the pro-inflammatory cytokine, interferon-γ. Moreover, heavy training loads are associated with elevated numbers of resting peripheral blood type-2 and regulatory T-cells, which characteristically produce the anti-inflammatory cytokines, interleukin-4 and interleukin-10, respectively. This appears to increase the risk of upper respiratory symptoms, potentially due to the cross-regulatory effect of interleukin-4 on interferon-γ production and immunosuppressive action of IL-10. Catecholamines significantly influence the number of peripheral blood T-cells in response to exercise. Whereas, glucocorticoids and prostaglandin E2 promote the production of anti-inflammatory cytokines by T-cells. In summary, strenuous exercise bouts and heavy training shifts T-cell immunity towards an anti-inflammatory state. This impairs the ability of the immune system to mount an inflammatory response to an immune challenge, which may weaken defences against intracellular pathogens (e.g. viruses), and increase the risk of infection and viral reactivation.


Asunto(s)
Antiinflamatorios/metabolismo , Citocinas/biosíntesis , Ejercicio Físico/fisiología , Terapia de Inmunosupresión , Linfocitos T/metabolismo , Humanos , Estrés Fisiológico
13.
Dysphagia ; 31(3): 407-15, 2016 06.
Artículo en Inglés | MEDLINE | ID: mdl-26803776

RESUMEN

This study evaluated hospital readiness and interprofessional clinical reasoning in speech-language pathology and dietetics students following a simulation-based teaching package. Thirty-one students participated in two half-day simulation workshops. The training included orientation to the hospital setting, part-task skill learning and immersive simulated cases. Students completed workshop evaluation forms. They filled in a 10-question survey regarding confidence, knowledge and preparedness for working in a hospital environment before and immediately after the workshops. Students completed written 15-min clinical vignettes at 1 month prior to training, immediately prior to training and immediately after training. A marking rubric was devised to evaluate the responses to the clinical vignettes within a framework of interprofessional education. The simulation workshops were well received by all students. There was a significant increase in students' self-ratings of confidence, preparedness and knowledge following the study day (p < .001). There was a significant increase in student overall scores in clinical vignettes after training with the greatest increase in clinical reasoning (p < .001). Interprofessional simulation-based training has benefits in developing hospital readiness and clinical reasoning in allied health students.


Asunto(s)
Competencia Clínica , Dietética/educación , Entrenamiento Simulado/métodos , Patología del Habla y Lenguaje/educación , Estudiantes del Área de la Salud/psicología , Adulto , Trastornos de Deglución , Evaluación Educacional , Femenino , Conocimientos, Actitudes y Práctica en Salud , Humanos , Masculino , Encuestas y Cuestionarios
14.
Graefes Arch Clin Exp Ophthalmol ; 253(11): 1841-50, 2015 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-26340868

RESUMEN

BACKGROUND: Glaucoma is a leading cause of irreversible blindness worldwide. A major symptom of this pathology is the loss to the visual field in a peripheral to central pattern. Flavonoids are polyphenol compounds sourced from plants, commonly found in green tea, red wine and cocoa, and they have neuroprotective and antioxidant characteristics proposed to be advantageous within the context of glaucoma. Currently, the literature presents conflicting evidence regarding the effect of flavonoids on patients with glaucoma and ocular hypertension; hence a systematic review and meta-analysis was conducted. METHOD: Databases included in our literature search were EMBASE (1980-present), MEDLINE Ovid, Alternative and Complementary Medicine Database (AMED), Cumulative Index to Nursing and Allied Health Literature (CINAHL) and Cochrane Central Register of Controlled Trials (CENTRAL). Meta-analysis was performed using RevMan 5 (Review Manager) 5 software, version 5.3 (The Nordic Cochrane Centre, The Cochrane Collaboration, Copenhagen). The primary outcomes were visual field mean deviation (MD) and intraocular pressure (IOP). Secondary outcomes were ocular blood flow and blood pressure (BP). CONCLUSION: Meta-analyses showed that flavonoids have a promising role in improving visual function in patients with glaucoma and ocular hypertension (OHT), and appear to play a part in both improving and slowing the progression of visual field loss.


Asunto(s)
Flavonoides/uso terapéutico , Glaucoma/tratamiento farmacológico , Agudeza Visual/efectos de los fármacos , Presión Sanguínea/efectos de los fármacos , Glaucoma/fisiopatología , Humanos , Presión Intraocular/efectos de los fármacos , Hipertensión Ocular/tratamiento farmacológico , Hipertensión Ocular/fisiopatología , Campos Visuales/efectos de los fármacos
15.
Nutrients ; 16(2)2024 Jan 11.
Artículo en Inglés | MEDLINE | ID: mdl-38257125

RESUMEN

The neurotoxic effects of ozone exposure are related to neuroinflammation and increases in reactive oxygen species (ROS). This study aimed to assess inflammation, Brain-Derived Neurotrophic Factor (BDNF), and cognition in healthy male cyclists following polyphenol supplementation and exercise in an ozone-polluted environment. Ten male cyclists initially completed a maximal incremental test and maximal effort 4 km time trial in ambient air. Cyclists then completed two trials in an ozone-polluted environment (0.25 ppm) following 7 days of supplementation with either polyphenol (POLY) or placebo (PL). Experimental trials consisted of a three-stage submaximal test followed by a 4 km time trial. Blood samples were drawn pre- and post-exercise, and analyzed for BDNF, interleukin 6 (IL-6), interleukin 10 (IL-10) and tumor necrosis factor (TNF-α). The Stroop test and serial subtraction task were performed before ozone exposure and again after the 4 km TT. Serum BDNF increased post-exercise (p < 0.0001), and positive differences were observed post-exercise in the ozone POLY group relative to PL (p = 0.013). Plasma IL-6 increased post-exercise (p = 0.0015), and TNF-α increased post-ozone exposure (p = 0.0018). There were no differences in Stroop or serial subtraction tasks pre- or post-exercise. Exercise increases BDNF in ozone.


Asunto(s)
Citocinas , Ozono , Masculino , Humanos , Interleucina-6 , Factor de Necrosis Tumoral alfa , Factor Neurotrófico Derivado del Encéfalo , Cognición , Anticuerpos , Polifenoles/farmacología , Suplementos Dietéticos
16.
Curr Dev Nutr ; 8(5): 102158, 2024 May.
Artículo en Inglés | MEDLINE | ID: mdl-38716086

RESUMEN

The microbiota-gut-brain axis is a promising target to alleviate the growing burden of neurologic and mental health disorders. Dietary polyphenols act on multiple components of the microbiota-gut-brain axis, but this complex relationship requires further attention. This randomized, placebo-controlled, double-blind, crossover trial (ACTRN12622000850774) compared 4 wk of a commercially available flavonoid-rich blackcurrant beverage (FBB; 151 mg anthocyanins, 308 mg total polyphenols) with placebo in 40 healthy females (18-45 y). The primary outcome of stress reactivity was assessed by change in present feelings of stress, mood, and fatigue before and after completing a 20-min cognitive stressor [Purple multitasking framework (MTF)]. Secondary end points included cognitive performance (MTF), mood [profile of mood states (POMS)], sleep (Pittsburgh Sleep Quality Index), fecal microbiome composition and functional potential (shotgun sequencing), and blood biomarker concentrations (brain-derived neurotrophic factor, tryptophan, kynurenine, and interleukin 6). Statistical analyses were conducted on an intention-to-treat basis using linear mixed-effect models. Thirty-eight participants completed both intervention arms. There was no significant treatment effect on the primary outcome of stress reactivity. Compared with placebo, working memory (letter retrieval scores from MTF), and anxiety/tension and anger/hostility domains of the POMS improved with FBB supplementation (time × intervention interaction; P < 0.05). There were no treatment effects on gut microbiome composition or functional potential. Baseline abundances of Bifidobacterium genera and species (Bifidobacterium longum and Bifidobacterium bifidum) tended to be higher in participants with the greatest improvements in letter retrieval scores with FBB supplementation (nominally significant, P < 0.05). In conclusion, 4-wk FBB supplementation improved secondary outcomes of working memory performance during multitasking and mood outcomes in healthy adult females. These results should be confirmed in a larger cohort with a longer duration of follow-up.

17.
Curr Opin Otolaryngol Head Neck Surg ; 31(6): 350-356, 2023 Dec 01.
Artículo en Inglés | MEDLINE | ID: mdl-37523160

RESUMEN

PURPOSE OF REVIEW: This review aims to deliver expert insights on the current advances and challenges in managing malnutrition in aged care settings, with a specific emphasis on the interaction between dysphagia and diet. RECENT FINDINGS: Several reviews identify the high prevalence of dysphagia in aged care facilities and highlight the correlation between dysphagia and malnutrition. Recent studies underscore the importance of nutrition and cancer screening and assessment, yet highlight the lack of consensus on the definitive tools to be used. There is a growth in employing innovative implementations for enhancing swallowing function and optimizing texture-modified foods. SUMMARY: Early identification and strategic interventions are vital for managing malnutrition and dysphagia in aged care facilities, as these conditions are widespread and lead to a higher risk of complications. Although nutritional strategies have shown potential in enhancing oral intake for residents requiring texture-modified foods, lack of investigation on functional outcomes and long-term impact have been highlighted, emphasizing the need for continued research and development of effective assessment tools and targeted interventions to optimize the care for this at-risk group.


Asunto(s)
Trastornos de Deglución , Desnutrición , Humanos , Anciano , Trastornos de Deglución/diagnóstico , Trastornos de Deglución/etiología , Trastornos de Deglución/terapia , Dieta , Desnutrición/diagnóstico , Desnutrición/etiología , Desnutrición/prevención & control , Factores de Riesgo , Deglución
18.
J Nutr Educ Behav ; 55(1): 38-47, 2023 01.
Artículo en Inglés | MEDLINE | ID: mdl-36372660

RESUMEN

Implementing behavior strategies into nutrition research requires consideration. The Nine Principles framework was used to develop an eHealth behavior change support (BCS) program to enhance young adults' adherence to (1) eating healthily and (2) recording dietary intake when participating in a randomized control trial. The Theory of Planned Behavior and qualitative focus group data informed a 10-week pilot of the BCS delivered on Facebook and texts. The BCS appeared to support optimal dietary recording and maintained dietary behaviors, suggesting using a framework underpinned by theory and user-centered design may be a promising avenue to enhance adherence in randomized control trials.


Asunto(s)
Dieta , Telemedicina , Humanos , Adulto Joven , Ingestión de Alimentos , Conductas Relacionadas con la Salud , Conducta Alimentaria
19.
BMC Nutr ; 9(1): 134, 2023 Nov 21.
Artículo en Inglés | MEDLINE | ID: mdl-37990250

RESUMEN

BACKGROUND: Behaviour change science is proposed to improve participant retention and enhance the validity of trials. However, researchers seldom systematically consider and implement behaviour change strategies within trials for this purpose. The objective of this article is to evaluate how an eHealth behaviour change support (BCS) program enhances young adults' adherence to behaviours required within a dietary intervention. METHODS: The Nine Principles framework was used to develop BCS to implement across both arms of a 10-week randomised parallel-group intervention to enhance adherence to (i) eating healthily and (ii) reporting dietary intake. Key components of the BCS included access to a dietitian-led Facebook group, text reminders, and food delivery. Effectiveness was measured using the following analyses of the 78 participants who completed the study; pre-post change in targeted dietary habits over time using a subscore of the Healthy Diet Habits Index, questionnaire to assess change in perception of barriers to eating healthily over time, Facebook group engagement, and impact evaluation of the BCS. Participants received a dietary reporting score out of 100 to assess adherence across the 10 weeks. RESULTS: The total Healthy Diet Habits Index subscore out of 16 significantly increased from baseline to week 10 (10.6 ± 2.6 to 11.2 ± 2.6, p value < 0.05), driven primarily by an increase in vegetable consumption. Overall adherence to reporting was high across the 10 weeks, with the total population mean reporting score 90.4 ± 14.6 out of 100. Relatively low Facebook engagement was observed. Adding objects to the environment, prompts/cues and removing reward appeared to be effective components of the BCS for enhancing adherence to the target behaviours. CONCLUSION: Using a behaviour change framework to support the design of randomised trials is a promising way to enhance participant adherence to study requirements that are typically considered burdensome, such as dietary reporting. It also enables researchers to identify and replicate effective components of BCS, including behaviour change techniques and modes of delivery. Further research into the use of different behaviour change frameworks for this purpose is warranted. TRIAL REGISTRATION: ClinicalTrials.gov Identifier: NCT04869163; https://clinicaltrials.gov/ct2/show/NCT04869163 . (03/05/2021).

20.
Curr Dev Nutr ; 7(11): 102018, 2023 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-38026570

RESUMEN

Background: Genetic variation may significantly impact an individual's susceptibility to diseases, particularly when combined with specific nutrients. Additionally, genetic variations can lead to interindividual differences in metabolic responses. Objective: The present study explores the association between gene variants and observed interindividual differences in metabolic responses. Methods: The study included 30 healthy males (aged 20-34) who underwent a fasting period and subsequently consumed a standardized meal. Blood samples were collected both before and after the meal to assess metabolic changes. BMI served as an indirect measure for assessing physiological responses associated with body composition. Appetite changes were assessed using an online Visual Analog 100-point Scale. Buccal swabs were collected to analyze genetic variants in single nucleotide polymorphisms (SNPs). Results: The data underwent multiple regression analysis, revealing significant associations with 3 SNPs and their metabolic status: the insulin-receptor substrate 1 (IRS1) gene variant rs2943641, genotypes CT and CC, with elevated fasting insulin levels (R2 = 0.639, P = < 0.0001); the mitochondrial uncoupling protein 1 (UCP1) gene variant rs1800592, genotypes GG and GA, with increased BMI (R2 = 0.261, P = 0.007); and the peroxisome proliferator-activated receptor γ2 (PPARγ2) gene variant rs1801282, genotypes GG and GC, with increased BMI (R2 = 0.200, P = 0.024). Conclusions: Therefore, our study established significant associations between these 3 SNPs and differences in fasting insulin levels and BMI within our cohort.

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