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1.

PRC2.1- and PRC2.2-specific accessory proteins drive recruitment of different forms of canonical PRC1.

Glancy, Eleanor; Wang, Cheng; Tuck, Ellen; Healy, Evan; Amato, Simona; Neikes, Hannah K; Mariani, Andrea; Mucha, Marlena; Vermeulen, Michiel; Pasini, Diego; Bracken, Adrian P.

Mol Cell ; 83(9): 1393-1411.e7, 2023 05 04.

Artículo en Inglés | MEDLINE | ID: mdl-37030288

2.

The corepressors GPS2 and SMRT control enhancer and silencer remodeling via eRNA transcription during inflammatory activation of macrophages.

Huang, Zhiqiang; Liang, Ning; Goñi, Saioa; Damdimopoulos, Anastasios; Wang, Cheng; Ballaire, Raphaelle; Jager, Jennifer; Niskanen, Henri; Han, Hongya; Jakobsson, Tomas; Bracken, Adrian P; Aouadi, Myriam; Venteclef, Nicolas; Kaikkonen, Minna U; Fan, Rongrong; Treuter, Eckardt.

Mol Cell ; 81(5): 953-968.e9, 2021 03 04.

Artículo en Inglés | MEDLINE | ID: mdl-33503407

3.

If You Like It Then You Shoulda Put Two "RINGs" on It: Delineating the Roles of vPRC1 and cPRC1.

Healy, Evan; Bracken, Adrian P.

Mol Cell ; 77(4): 685-687, 2020 02 20.

Artículo en Inglés | MEDLINE | ID: mdl-32084351

4.

PRC2.1 and PRC2.2 Synergize to Coordinate H3K27 Trimethylation.

Healy, Evan; Mucha, Marlena; Glancy, Eleanor; Fitzpatrick, Darren J; Conway, Eric; Neikes, Hannah K; Monger, Craig; Van Mierlo, Guido; Baltissen, Marijke P; Koseki, Yoko; Vermeulen, Michiel; Koseki, Haruhiko; Bracken, Adrian P.

Mol Cell ; 76(3): 437-452.e6, 2019 11 07.

Artículo en Inglés | MEDLINE | ID: mdl-31521505

5.

Dangerous liaisons: interplay between SWI/SNF, NuRD, and Polycomb in chromatin regulation and cancer.

Bracken, Adrian P; Brien, Gerard L; Verrijzer, C Peter.

Genes Dev ; 33(15-16): 936-959, 2019 08 01.

Artículo en Inglés | MEDLINE | ID: mdl-31123059

6.

The H3K36me2 Methyltransferase Nsd1 Demarcates PRC2-Mediated H3K27me2 and H3K27me3 Domains in Embryonic Stem Cells.

Streubel, Gundula; Watson, Ariane; Jammula, Sri Ganesh; Scelfo, Andrea; Fitzpatrick, Darren J; Oliviero, Giorgio; McCole, Rachel; Conway, Eric; Glancy, Eleanor; Negri, Gian Luca; Dillon, Eugene; Wynne, Kieran; Pasini, Diego; Krogan, Nevan J; Bracken, Adrian P; Cagney, Gerard.

Mol Cell ; 70(2): 371-379.e5, 2018 04 19.

Artículo en Inglés | MEDLINE | ID: mdl-29606589

7.

A Family of Vertebrate-Specific Polycombs Encoded by the LCOR/LCORL Genes Balance PRC2 Subtype Activities.

Conway, Eric; Jerman, Emilia; Healy, Evan; Ito, Shinsuke; Holoch, Daniel; Oliviero, Giorgio; Deevy, Orla; Glancy, Eleanor; Fitzpatrick, Darren J; Mucha, Marlena; Watson, Ariane; Rice, Alan M; Chammas, Paul; Huang, Christine; Pratt-Kelly, Indigo; Koseki, Yoko; Nakayama, Manabu; Ishikura, Tomoyuki; Streubel, Gundula; Wynne, Kieran; Hokamp, Karsten; McLysaght, Aoife; Ciferri, Claudio; Di Croce, Luciano; Cagney, Gerard; Margueron, Raphaël; Koseki, Haruhiko; Bracken, Adrian P.

Mol Cell ; 70(3): 408-421.e8, 2018 05 03.

Artículo en Inglés | MEDLINE | ID: mdl-29628311

8.

Corrigendum: The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells.

Bracken, Adrian P; Kleine-Kohlbrecher, Daniela; Dietrich, Nikolaj; Pasini, Diego; Gargiulo, Gaetano; Beekman, Chantal; Theilgaard-Mönch, Kim; Minucci, Saverio; Porse, Bo T; Marine, Jean-Christophe; Hansen, Klaus H; Helin, Kristian.

Genes Dev ; 37(17-18): 861, 2023 Sep 01.

Artículo en Inglés | MEDLINE | ID: mdl-37852794

9.

Dual functionality of cis-regulatory elements as developmental enhancers and Polycomb response elements.

Erceg, Jelena; Pakozdi, Tibor; Marco-Ferreres, Raquel; Ghavi-Helm, Yad; Girardot, Charles; Bracken, Adrian P; Furlong, Eileen E M.

Genes Dev ; 31(6): 590-602, 2017 03 15.

Artículo en Inglés | MEDLINE | ID: mdl-28381411

10.

Author Correction: EZH2 is downstream of the pRB-E2F pathway, essential for proliferation and amplified in cancer.

Bracken, Adrian P; Pasini, Diego; Capra, Maria; Prosperini, Elena; Colli, Elena; Helin, Kristian.

EMBO J ; 43(5): 886, 2024 Mar.

Artículo en Inglés | MEDLINE | ID: mdl-38347304

11.

A chromatin-independent role of Polycomb-like 1 to stabilize p53 and promote cellular quiescence.

Brien, Gerard L; Healy, Evan; Jerman, Emilia; Conway, Eric; Fadda, Elisa; O'Donovan, Darragh; Krivtsov, Andrei V; Rice, Alan M; Kearney, Conor J; Flaus, Andrew; McDade, Simon S; Martin, Seamus J; McLysaght, Aoife; O'Connell, David J; Armstrong, Scott A; Bracken, Adrian P.

Genes Dev ; 29(21): 2231-43, 2015 Nov 01.

Artículo en Inglés | MEDLINE | ID: mdl-26494712

12.

PRC2 functions in development and congenital disorders.

Deevy, Orla; Bracken, Adrian P.

Development ; 146(19)2019 10 01.

Artículo en Inglés | MEDLINE | ID: mdl-31575610

13.

Analytical Validation of a Novel 6-Gene Signature for Prediction of Distant Recurrence in Estrogen Receptor-Positive, HER2-Negative, Early-Stage Breast Cancer.

Loughman, Tony; Barron, Stephen; Wang, Chan-Ju Angel; Dynoodt, Peter; Fender, Bozena; Lopez-Ruiz, Cesar; Stapleton, Sharon; Fabre, Aurelie; Quinn, Cecily; Nodin, Bjorn; Jirström, Karin; Razmara, Fatemeh; O'Grady, Anthony; Baird, Anne-Marie; Gray, Steven G; Freixo, Ana; Moelans, Cathy B; van Diest, Paul J; Duffy, Michael J; O'Leary, Desmond; Crown, John; Bracken, Adrian P; Gallagher, William M.

Clin Chem ; 68(6): 837-847, 2022 06 01.

Artículo en Inglés | MEDLINE | ID: mdl-35312747

14.

Fam60a defines a variant Sin3a-Hdac complex in embryonic stem cells required for self-renewal.

Streubel, Gundula; Fitzpatrick, Darren J; Oliviero, Giorgio; Scelfo, Andrea; Moran, Bruce; Das, Sudipto; Munawar, Nayla; Watson, Ariane; Wynne, Kieran; Negri, Gian Luca; Dillon, Eugene T; Jammula, SriGanesh; Hokamp, Karsten; O'Connor, Darran P; Pasini, Diego; Cagney, Gerard; Bracken, Adrian P.

EMBO J ; 36(15): 2216-2232, 2017 08 01.

Artículo en Inglés | MEDLINE | ID: mdl-28554894

15.

MED23: a new Mediator of H2B monoubiquitylation.

Streubel, Gundula; Bracken, Adrian P.

EMBO J ; 34(23): 2863-4, 2015 Dec 02.

Artículo en Inglés | MEDLINE | ID: mdl-26438725

16.

Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.

Oliviero, Giorgio; Brien, Gerard L; Waston, Ariane; Streubel, Gundula; Jerman, Emilia; Andrews, Darrell; Doyle, Benjamin; Munawar, Nayla; Wynne, Kieran; Crean, John; Bracken, Adrian P; Cagney, Gerard.

Mol Cell Proteomics ; 15(11): 3450-3460, 2016 11.

Artículo en Inglés | MEDLINE | ID: mdl-27634302

17.

Myeloid cell nuclear differentiation antigen controls the pathogen-stimulated type I interferon cascade in human monocytes by transcriptional regulation of IRF7.

Gu, Lili; Casserly, David; Brady, Gareth; Carpenter, Susan; Bracken, Adrian P; Fitzgerald, Katherine A; Unterholzner, Leonie; Bowie, Andrew G.

Nat Commun ; 13(1): 14, 2022 01 10.

Artículo en Inglés | MEDLINE | ID: mdl-35013241

18.

Macrophage innate training induced by IL-4 and IL-13 activation enhances OXPHOS driven anti-mycobacterial responses.

Lundahl, Mimmi L E; Mitermite, Morgane; Ryan, Dylan Gerard; Case, Sarah; Williams, Niamh C; Yang, Ming; Lynch, Roisin I; Lagan, Eimear; Lebre, Filipa M; Gorman, Aoife L; Stojkovic, Bojan; Bracken, Adrian P; Frezza, Christian; Sheedy, Frederick J; Scanlan, Eoin M; O'Neill, Luke A J; Gordon, Stephen V; Lavelle, Ed C.

Elife ; 112022 09 29.

Artículo en Inglés | MEDLINE | ID: mdl-36173104

19.

Transcriptomics: unravelling the biology of transcription factors and chromatin remodelers during development and differentiation.

Brien, Gerard L; Bracken, Adrian P.

Semin Cell Dev Biol ; 20(7): 835-41, 2009 Sep.

Artículo en Inglés | MEDLINE | ID: mdl-19682593

20.

Profiling cancer.

Ciro, Marco; Bracken, Adrian P; Helin, Kristian.

Curr Opin Cell Biol ; 15(2): 213-20, 2003 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-12648678

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