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1.

Alternative donor BMT with posttransplant cyclophosphamide as initial therapy for acquired severe aplastic anemia.

DeZern, Amy E; Zahurak, Marianna; Symons, Heather J; Cooke, Kenneth R; Huff, Carol Ann; Jain, Tania; Swinnen, Lode J; Imus, Philip H; Wagner-Johnston, Nina D; Ambinder, Richard F; Levis, Mark; Luznik, Leo; Bolaños-Meade, Javier; Fuchs, Ephraim J; Jones, Richard J; Brodsky, Robert A.

Blood ; 141(25): 3031-3038, 2023 06 22.

Artículo en Inglés | MEDLINE | ID: mdl-37084383

2.

A bispecific inhibitor of complement and coagulation blocks activation in complementopathy models via a novel mechanism.

Andersen, John F; Lei, Haotian; Strayer, Ethan C; Kanai, Tapan; Pham, Van; Pan, Xiang-Zuo; Alvarenga, Patricia Hessab; Gerber, Gloria F; Asojo, Oluwatoyin A; Francischetti, Ivo M B; Brodsky, Robert A; Valenzuela, Jesus G; Ribeiro, José M C.

Blood ; 141(25): 3109-3121, 2023 06 22.

Artículo en Inglés | MEDLINE | ID: mdl-36947859

3.

Silent cerebral infarction during immune TTP remission: prevalence, predictors, and impact on cognition.

Chaturvedi, Shruti; Yu, Jia; Brown, Jenna; Wei, Aria; Selvakumar, Sruthi; Gerber, Gloria F; Moliterno, Alison R; Streiff, Michael B; Kraus, Peggy; Logue, Claire M; Yui, Jennifer C; Naik, Rakhi P; Latif, Hira; Lanzkron, Sophie M; Braunstein, Evan M; Brodsky, Robert A; Gottesman, Rebecca F; Lin, Doris D.

Blood ; 142(4): 325-335, 2023 07 27.

Artículo en Inglés | MEDLINE | ID: mdl-37216688

4.

Pegcetacoplan for paroxysmal nocturnal hemoglobinuria.

Gerber, Gloria F; Brodsky, Robert A.

Blood ; 139(23): 3361-3365, 2022 06 09.

Artículo en Inglés | MEDLINE | ID: mdl-35349667

5.

How I treat paroxysmal nocturnal hemoglobinuria.

Brodsky, Robert A.

Blood ; 137(10): 1304-1309, 2021 03 11.

Artículo en Inglés | MEDLINE | ID: mdl-33512400

6.

Phase 2 study of danicopan in patients with paroxysmal nocturnal hemoglobinuria with an inadequate response to eculizumab.

Kulasekararaj, Austin G; Risitano, Antonio M; Maciejewski, Jaroslaw P; Notaro, Rosario; Browett, Peter; Lee, Jong Wook; Huang, Mingjun; Geffner, Michael; Brodsky, Robert A.

Blood ; 138(20): 1928-1938, 2021 11 18.

Artículo en Inglés | MEDLINE | ID: mdl-34314483

7.

Concomitant Immunosuppressive Therapy and Eculizumab Use in Patients with Paroxysmal Nocturnal Hemoglobinuria: An International PNH Registry Analysis.

Hill, Anita; de Latour, Régis Peffault; Kulasekararaj, Austin G; Griffin, Morag; Brodsky, Robert A; Maciejewski, Jaroslaw P; Marantz, Jing L; Gustovic, Philippe; Schrezenmeier, Hubert.

Acta Haematol ; 146(1): 1-13, 2023.

Artículo en Inglés | MEDLINE | ID: mdl-36108594

8.

Direct activation of the alternative complement pathway by SARS-CoV-2 spike proteins is blocked by factor D inhibition.

Yu, Jia; Yuan, Xuan; Chen, Hang; Chaturvedi, Shruti; Braunstein, Evan M; Brodsky, Robert A.

Blood ; 136(18): 2080-2089, 2020 10 29.

Artículo en Inglés | MEDLINE | ID: mdl-32877502

9.

Complement activity and complement regulatory gene mutations are associated with thrombosis in APS and CAPS.

Chaturvedi, Shruti; Braunstein, Evan M; Yuan, Xuan; Yu, Jia; Alexander, Alice; Chen, Hang; Gavriilaki, Eleni; Alluri, Ravi; Streiff, Michael B; Petri, Michelle; Crowther, Mark A; McCrae, Keith R; Brodsky, Robert A.

Blood ; 135(4): 239-251, 2020 01 23.

Artículo en Inglés | MEDLINE | ID: mdl-31812994

10.

Complement dysregulation is associated with severe COVID-19 illness.

Yu, Jia; Gerber, Gloria F; Chen, Hang; Yuan, Xuan; Chaturvedi, Shruti; Braunstein, Evan M; Brodsky, Robert A.

Haematologica ; 107(5): 1095-1105, 2022 05 01.

Artículo en Inglés | MEDLINE | ID: mdl-34289657

11.

Maternal and fetal outcomes of pregnancy occurring after a diagnosis of immune-mediated thrombotic thrombocytopenic purpura.

Brown, Jenna; Potugari, Bindu; Mazepa, Marshall A; Kohli, Ruhail; Moliterno, Alison R; Brodsky, Robert A; Vaught, Jason A; Burwick, Richard; Chaturvedi, Shruti.

Ann Hematol ; 101(10): 2159-2167, 2022 Oct.

Artículo en Inglés | MEDLINE | ID: mdl-35932324

12.

Reduced ADAMTS13 activity during TTP remission is associated with stroke in TTP survivors.

Upreti, Harshvardhan; Kasmani, Jamil; Dane, Kathryn; Braunstein, Evan M; Streiff, Michael B; Shanbhag, Satish; Moliterno, Alison R; Sperati, C John; Gottesman, Rebecca F; Brodsky, Robert A; Kickler, Thomas S; Chaturvedi, Shruti.

Blood ; 134(13): 1037-1045, 2019 09 26.

Artículo en Inglés | MEDLINE | ID: mdl-31431443

13.

Characterization of breakthrough hemolysis events observed in the phase 3 randomized studies of ravulizumab versus eculizumab in adults with paroxysmal nocturnal hemoglobinuria.

Brodsky, Robert A; Peffault de Latour, Régis; Rottinghaus, Scott T; Röth, Alexander; Risitano, Antonio M; Weitz, Ilene C; Hillmen, Peter; Maciejewski, Jaroslaw P; Szer, Jeff; Lee, Jong Wook; Kulasekararaj, Austin G; Volles, Lori; Damokosh, Andrew I; Ortiz, Stephan; Shafner, Lori; Liu, Peng; Hill, Anita; Schrezenmeier, Hubert.

Haematologica ; 106(1): 230-237, 2021 01 01.

Artículo en Inglés | MEDLINE | ID: mdl-31949012

14.

One-year outcomes from a phase 3 randomized trial of ravulizumab in adults with paroxysmal nocturnal hemoglobinuria who received prior eculizumab.

Kulasekararaj, Austin G; Hill, Anita; Langemeijer, Saskia; Wells, Richard; González Fernández, F Ataúlfo; Gaya, Anna; Ojeda Gutierrez, Emilio; Piatek, Caroline I; Mitchell, Lindsay; Usuki, Kensuke; Bosi, Alberto; Brodsky, Robert A; Ogawa, Masayo; Yu, Ji; Ortiz, Stephan; Röth, Alexander; Lee, Jong Wook; Peffault de Latour, Régis.

Eur J Haematol ; 106(3): 389-397, 2021 Mar.

Artículo en Inglés | MEDLINE | ID: mdl-33301613

15.

Major adverse cardiovascular events in survivors of immune-mediated thrombotic thrombocytopenic purpura.

Brodsky, Max A; Sukumar, Senthil; Selvakumar, Sruthi; Yanek, Lisa; Hussain, Sarah; Mazepa, Marshall A; Braunstein, Evan M; Moliterno, Alison R; Kickler, Thomas S; Brodsky, Robert A; Cataland, Spero R; Chaturvedi, Shruti.

Am J Hematol ; 96(12): 1587-1594, 2021 12 01.

Artículo en Inglés | MEDLINE | ID: mdl-34460124

16.

Pain Experiences of Adults With Sickle Cell Disease and Hematopoietic Stem Cell Transplantation: A Qualitative Study.

Abu Al Hamayel, Nebras; Waldfogel, Julie M; Hannum, Susan M; Brodsky, Robert A; Bolaños-Meade, Javier; Gamper, Christopher J; Jones, Richard J; Dy, Sydney M.

Pain Med ; 22(8): 1753-1759, 2021 08 06.

Artículo en Inglés | MEDLINE | ID: mdl-33674866

17.

Diagnostic utility of telomere length testing in a hospital-based setting.

Alder, Jonathan K; Hanumanthu, Vidya Sagar; Strong, Margaret A; DeZern, Amy E; Stanley, Susan E; Takemoto, Clifford M; Danilova, Ludmila; Applegate, Carolyn D; Bolton, Stephen G; Mohr, David W; Brodsky, Robert A; Casella, James F; Greider, Carol W; Jackson, J Brooks; Armanios, Mary.

Proc Natl Acad Sci U S A ; 115(10): E2358-E2365, 2018 03 06.

Artículo en Inglés | MEDLINE | ID: mdl-29463756

18.

Shortened-Duration Immunosuppressive Therapy after Nonmyeloablative, Related HLA-Haploidentical or Unrelated Peripheral Blood Grafts and Post-Transplantation Cyclophosphamide.

DeZern, Amy E; Elmariah, Hany; Zahurak, Marianna; Rosner, Gary L; Gladstone, Douglas E; Ali, Syed Abbas; Huff, Carol Ann; Swinnen, Lode J; Imus, Phil; Borrello, Ivan; Wagner-Johnston, Nina D; Ambinder, Richard F; Brodsky, Robert A; Cooke, Kenneth; Luznik, Leo; Fuchs, Ephraim J; Bolaños-Meade, Javier; Jones, Richard J.

Biol Blood Marrow Transplant ; 26(11): 2075-2081, 2020 11.

Artículo en Inglés | MEDLINE | ID: mdl-32818556

19.

Ex vivo assays to detect complement activation in complementopathies.

Yuan, Xuan; Yu, Jia; Gerber, Gloria; Chaturvedi, Shruti; Cole, Michael; Chen, Hang; Metjian, Ara; Sperati, C John; Braunstein, Evan M; Brodsky, Robert A.

Clin Immunol ; 221: 108616, 2020 12.

Artículo en Inglés | MEDLINE | ID: mdl-33148511

20.

Pharmacokinetic and pharmacodynamic effects of ravulizumab and eculizumab on complement component 5 in adults with paroxysmal nocturnal haemoglobinuria: results of two phase 3 randomised, multicentre studies.

Peffault de Latour, Régis; Brodsky, Robert A; Ortiz, Stephan; Risitano, Antonio M; Jang, Jun H; Hillmen, Peter; Kulagin, Alexander D; Kulasekararaj, Austin G; Rottinghaus, Scott T; Aguzzi, Rasha; Gao, Xiang; Wells, Richard A; Szer, Jeff.

Br J Haematol ; 191(3): 476-485, 2020 11.

Artículo en Inglés | MEDLINE | ID: mdl-32449174

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