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1.

Individualised neoantigen therapy mRNA-4157 (V940) plus pembrolizumab versus pembrolizumab monotherapy in resected melanoma (KEYNOTE-942): a randomised, phase 2b study.

Weber, Jeffrey S; Carlino, Matteo S; Khattak, Adnan; Meniawy, Tarek; Ansstas, George; Taylor, Matthew H; Kim, Kevin B; McKean, Meredith; Long, Georgina V; Sullivan, Ryan J; Faries, Mark; Tran, Thuy T; Cowey, C Lance; Pecora, Andrew; Shaheen, Montaser; Segar, Jennifer; Medina, Theresa; Atkinson, Victoria; Gibney, Geoffrey T; Luke, Jason J; Thomas, Sajeve; Buchbinder, Elizabeth I; Healy, Jane A; Huang, Mo; Morrissey, Manju; Feldman, Igor; Sehgal, Vasudha; Robert-Tissot, Celine; Hou, Peijie; Zhu, Lili; Brown, Michelle; Aanur, Praveen; Meehan, Robert S; Zaks, Tal.

Lancet ; 403(10427): 632-644, 2024 Feb 17.

Artículo en Inglés | MEDLINE | ID: mdl-38246194

2.

Five-Year Survival with Combined Nivolumab and Ipilimumab in Advanced Melanoma.

Larkin, James; Chiarion-Sileni, Vanna; Gonzalez, Rene; Grob, Jean-Jacques; Rutkowski, Piotr; Lao, Christopher D; Cowey, C Lance; Schadendorf, Dirk; Wagstaff, John; Dummer, Reinhard; Ferrucci, Pier F; Smylie, Michael; Hogg, David; Hill, Andrew; Márquez-Rodas, Ivan; Haanen, John; Guidoboni, Massimo; Maio, Michele; Schöffski, Patrick; Carlino, Matteo S; Lebbé, Céleste; McArthur, Grant; Ascierto, Paolo A; Daniels, Gregory A; Long, Georgina V; Bastholt, Lars; Rizzo, Jasmine I; Balogh, Agnes; Moshyk, Andriy; Hodi, F Stephen; Wolchok, Jedd D.

N Engl J Med ; 381(16): 1535-1546, 2019 10 17.

Artículo en Inglés | MEDLINE | ID: mdl-31562797

3.

Real-World Clinical Outcomes in Patients with Locally Advanced or Metastatic Merkel Cell Carcinoma Treated in U.S. Oncology Clinical Practices: Results from SPEAR-Merkel.

Bhanegaonkar, Abhijeet; Liu, Frank X; Boyd, Marley; Fulcher, Nicole; Kim, Ruth; Krulewicz, Stan; Smith, Jodi; Cowey, C Lance.

Oncologist ; 26(9): e1633-e1643, 2021 09.

Artículo en Inglés | MEDLINE | ID: mdl-34101298

4.

Adjuvant nivolumab versus ipilimumab in resected stage IIIB-C and stage IV melanoma (CheckMate 238): 4-year results from a multicentre, double-blind, randomised, controlled, phase 3 trial.

Ascierto, Paolo A; Del Vecchio, Michele; Mandalá, Mario; Gogas, Helen; Arance, Ana M; Dalle, Stephane; Cowey, C Lance; Schenker, Michael; Grob, Jean-Jacques; Chiarion-Sileni, Vanna; Márquez-Rodas, Iván; Butler, Marcus O; Maio, Michele; Middleton, Mark R; de la Cruz-Merino, Luis; Arenberger, Petr; Atkinson, Victoria; Hill, Andrew; Fecher, Leslie A; Millward, Michael; Khushalani, Nikhil I; Queirolo, Paola; Lobo, Maurice; de Pril, Veerle; Loffredo, John; Larkin, James; Weber, Jeffrey.

Lancet Oncol ; 21(11): 1465-1477, 2020 11.

Artículo en Inglés | MEDLINE | ID: mdl-32961119

5.

Adjuvant Nivolumab versus Ipilimumab in Resected Stage III or IV Melanoma.

Weber, Jeffrey; Mandala, Mario; Del Vecchio, Michele; Gogas, Helen J; Arance, Ana M; Cowey, C Lance; Dalle, Stéphane; Schenker, Michael; Chiarion-Sileni, Vanna; Marquez-Rodas, Ivan; Grob, Jean-Jacques; Butler, Marcus O; Middleton, Mark R; Maio, Michele; Atkinson, Victoria; Queirolo, Paola; Gonzalez, Rene; Kudchadkar, Ragini R; Smylie, Michael; Meyer, Nicolas; Mortier, Laurent; Atkins, Michael B; Long, Georgina V; Bhatia, Shailender; Lebbé, Celeste; Rutkowski, Piotr; Yokota, Kenji; Yamazaki, Naoya; Kim, Tae M; de Pril, Veerle; Sabater, Javier; Qureshi, Anila; Larkin, James; Ascierto, Paolo A.

N Engl J Med ; 377(19): 1824-1835, 2017 11 09.

Artículo en Inglés | MEDLINE | ID: mdl-28891423

6.

Overall Survival with Combined Nivolumab and Ipilimumab in Advanced Melanoma.

Wolchok, Jedd D; Chiarion-Sileni, Vanna; Gonzalez, Rene; Rutkowski, Piotr; Grob, Jean-Jacques; Cowey, C Lance; Lao, Christopher D; Wagstaff, John; Schadendorf, Dirk; Ferrucci, Pier F; Smylie, Michael; Dummer, Reinhard; Hill, Andrew; Hogg, David; Haanen, John; Carlino, Matteo S; Bechter, Oliver; Maio, Michele; Marquez-Rodas, Ivan; Guidoboni, Massimo; McArthur, Grant; Lebbé, Celeste; Ascierto, Paolo A; Long, Georgina V; Cebon, Jonathan; Sosman, Jeffrey; Postow, Michael A; Callahan, Margaret K; Walker, Dana; Rollin, Linda; Bhore, Rafia; Hodi, F Stephen; Larkin, James.

N Engl J Med ; 377(14): 1345-1356, 2017 10 05.

Artículo en Inglés | MEDLINE | ID: mdl-28889792

7.

A phase 2 study of glembatumumab vedotin, an antibody-drug conjugate targeting glycoprotein NMB, in patients with advanced melanoma.

Ott, Patrick A; Pavlick, Anna C; Johnson, Douglas B; Hart, Lowell L; Infante, Jeffrey R; Luke, Jason J; Lutzky, Jose; Rothschild, Neal E; Spitler, Lynn E; Cowey, C Lance; Alizadeh, Aaron R; Salama, April K; He, Yi; Hawthorne, Thomas R; Bagley, Rebecca G; Zhang, Joshua; Turner, Christopher D; Hamid, Omid.

Cancer ; 125(7): 1113-1123, 2019 04 01.

Artículo en Inglés | MEDLINE | ID: mdl-30690710

8.

Combined Nivolumab and Ipilimumab or Monotherapy in Untreated Melanoma.

Larkin, James; Chiarion-Sileni, Vanna; Gonzalez, Rene; Grob, Jean Jacques; Cowey, C Lance; Lao, Christopher D; Schadendorf, Dirk; Dummer, Reinhard; Smylie, Michael; Rutkowski, Piotr; Ferrucci, Pier F; Hill, Andrew; Wagstaff, John; Carlino, Matteo S; Haanen, John B; Maio, Michele; Marquez-Rodas, Ivan; McArthur, Grant A; Ascierto, Paolo A; Long, Georgina V; Callahan, Margaret K; Postow, Michael A; Grossmann, Kenneth; Sznol, Mario; Dreno, Brigitte; Bastholt, Lars; Yang, Arvin; Rollin, Linda M; Horak, Christine; Hodi, F Stephen; Wolchok, Jedd D.

N Engl J Med ; 373(1): 23-34, 2015 Jul 02.

Artículo en Inglés | MEDLINE | ID: mdl-26027431

9.

Real-world treatment outcomes in patients with metastatic Merkel cell carcinoma treated with chemotherapy in the USA.

Cowey, C Lance; Mahnke, Lisa; Espirito, Janet; Helwig, Christoph; Oksen, Dina; Bharmal, Murtuza.

Future Oncol ; 13(19): 1699-1710, 2017 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-28605939

10.

Phase II LEAP-004 Study of Lenvatinib Plus Pembrolizumab for Melanoma With Confirmed Progression on a Programmed Cell Death Protein-1 or Programmed Death Ligand 1 Inhibitor Given as Monotherapy or in Combination.

Arance, Ana; de la Cruz-Merino, Luis; Petrella, Teresa M; Jamal, Rahima; Ny, Lars; Carneiro, Ana; Berrocal, Alfonso; Márquez-Rodas, Ivan; Spreafico, Anna; Atkinson, Victoria; Costa Svedman, Fernanda; Mant, Andrew; Khattak, Muhammad A; Mihalcioiu, Catalin; Jang, Sekwon; Cowey, C Lance; Smith, Alan D; Hawk, Natalyn; Chen, Ke; Diede, Scott J; Krepler, Clemens; Long, Georgina V.

J Clin Oncol ; 41(1): 75-85, 2023 01 01.

Artículo en Inglés | MEDLINE | ID: mdl-35867951

11.

Long-Term Outcomes With Nivolumab Plus Ipilimumab or Nivolumab Alone Versus Ipilimumab in Patients With Advanced Melanoma.

Wolchok, Jedd D; Chiarion-Sileni, Vanna; Gonzalez, Rene; Grob, Jean-Jacques; Rutkowski, Piotr; Lao, Christopher D; Cowey, C Lance; Schadendorf, Dirk; Wagstaff, John; Dummer, Reinhard; Ferrucci, Pier Francesco; Smylie, Michael; Butler, Marcus O; Hill, Andrew; Márquez-Rodas, Ivan; Haanen, John B A G; Guidoboni, Massimo; Maio, Michele; Schöffski, Patrick; Carlino, Matteo S; Lebbé, Céleste; McArthur, Grant; Ascierto, Paolo A; Daniels, Gregory A; Long, Georgina V; Bas, Tuba; Ritchings, Corey; Larkin, James; Hodi, F Stephen.

J Clin Oncol ; 40(2): 127-137, 2022 01 10.

Artículo en Inglés | MEDLINE | ID: mdl-34818112

12.

Adjuvant nivolumab versus ipilimumab (CheckMate 238 trial): Reassessment of 4-year efficacy outcomes in patients with stage III melanoma per AJCC-8 staging criteria.

Larkin, James; Weber, Jeffrey; Del Vecchio, Michele; Gogas, Helen; Arance, Ana M; Dalle, Stephane; Cowey, C Lance; Schenker, Michael; Grob, Jean-Jacques; Chiarion-Sileni, Vanna; Márquez-Rodas, Iván; Butler, Marcus O; Di Giacomo, Anna Marie; Middleton, Mark R; De la Cruz-Merino, Luis; Arenberger, Petr; Atkinson, Victoria; Hill, Andrew; Fecher, Leslie A; Millward, Michael; Khushalani, Nikhil I; Queirolo, Paola; Long, Georgina V; Lobo, Maurice; Askelson, Margarita; Ascierto, Paolo A; Mandalá, Mario.

Eur J Cancer ; 173: 285-296, 2022 09.

Artículo en Inglés | MEDLINE | ID: mdl-35964471

13.

Adjuvant nivolumab for stage III/IV melanoma: evaluation of safety outcomes and association with recurrence-free survival.

Mandala, Mario; Larkin, James; Ascierto, Paolo Antonio; Del Vecchio, Michele; Gogas, Helen; Cowey, C Lance; Arance, Ana; Dalle, Stéphane; Schenker, Michael; Grob, Jean-Jacques; Chiarion-Sileni, Vanna; Marquez-Rodas, Ivan; Butler, Marcus O; Di Giacomo, Anna Maria; Lutzky, Jose; De La Cruz-Merino, Luis; Atkinson, Victoria; Arenberger, Petr; Hill, Andrew; Fecher, Leslie; Millward, Michael; Khushalani, Nikhil I; de Pril, Veerle; Lobo, Maurice; Weber, Jeffrey.

J Immunother Cancer ; 9(8)2021 08.

Artículo en Inglés | MEDLINE | ID: mdl-34452930

14.

Identifying treatment options for BRAFV600 wild-type metastatic melanoma: A SU2C/MRA genomics-enabled clinical trial.

LoRusso, Patricia M; Sekulic, Aleksandar; Sosman, Jeffrey A; Liang, Winnie S; Carpten, John; Craig, David W; Solit, David B; Bryce, Alan H; Kiefer, Jeffrey A; Aldrich, Jessica; Nasser, Sara; Halperin, Rebecca; Byron, Sara A; Pilat, Mary Jo; Boerner, Scott A; Durecki, Diane; Hendricks, William P D; Enriquez, Daniel; Izatt, Tyler; Keats, Jonathan; Legendre, Christophe; Markovic, Svetomir N; Weise, Amy; Naveed, Fatima; Schmidt, Jessica; Basu, Gargi D; Sekar, Shobana; Adkins, Jonathan; Tassone, Erica; Sivaprakasam, Karthigayini; Zismann, Victoria; Calvert, Valerie S; Petricoin, Emanuel F; Fecher, Leslie Anne; Lao, Christopher; Eder, J Paul; Vogelzang, Nicholas J; Perlmutter, Jane; Gorman, Mark; Manica, Barbara; Fox, Lisa; Schork, Nicholas; Zelterman, Daniel; DeVeaux, Michelle; Joseph, Richard W; Cowey, C Lance; Trent, Jeffrey M.

PLoS One ; 16(4): e0248097, 2021.

Artículo en Inglés | MEDLINE | ID: mdl-33826614

15.

Molecularly targeted agents for renal cell carcinoma: the next generation.

Cowey, C Lance; Hutson, Thomas E.

Clin Adv Hematol Oncol ; 8(5): 357-60, 361-4, 2010 May.

Artículo en Inglés | MEDLINE | ID: mdl-20551895

16.

Clinical outcomes among unresectable, locally advanced, and metastatic cutaneous squamous cell carcinoma patients treated with systemic therapy.

Cowey, C Lance; Robert, Nicholas J; Espirito, Janet L; Davies, Kalatu; Frytak, Jennifer; Lowy, Israel; Fury, Matthew G.

Cancer Med ; 9(20): 7381-7387, 2020 10.

Artículo en Inglés | MEDLINE | ID: mdl-32578965

17.

Renal cell carcinoma.

Garcia, Jorge A; Cowey, C Lance; Godley, Paul A.

Curr Opin Oncol ; 21(3): 266-71, 2009 May.

Artículo en Inglés | MEDLINE | ID: mdl-19339887

18.

VHL gene mutations in renal cell carcinoma: role as a biomarker of disease outcome and drug efficacy.

Cowey, C Lance; Rathmell, W Kimryn.

Curr Oncol Rep ; 11(2): 94-101, 2009 Mar.

Artículo en Inglés | MEDLINE | ID: mdl-19216840

19.

Efficacy, Safety, and Tolerability of Approved Combination BRAF and MEK Inhibitor Regimens for BRAF-Mutant Melanoma.

Hamid, Omid; Cowey, C Lance; Offner, Michelle; Faries, Mark; Carvajal, Richard D.

Cancers (Basel) ; 11(11)2019 Oct 24.

Artículo en Inglés | MEDLINE | ID: mdl-31653096

20.

Real-world treatment patterns and clinical outcomes among patients with advanced melanoma: A retrospective, community oncology-based cohort study (A STROBE-compliant article).

Cowey, C Lance; Liu, Frank Xiaoqing; Boyd, Marley; Aguilar, Kathleen M; Krepler, Clemens.

Medicine (Baltimore) ; 98(28): e16328, 2019 Jul.

Artículo en Inglés | MEDLINE | ID: mdl-31305421

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