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1.
Br J Dermatol ; 189(4): 459-466, 2023 09 15.
Artículo en Inglés | MEDLINE | ID: mdl-37291902

RESUMEN

BACKGROUND: Psychological and mental health difficulties are common in children and young people (CYP) living with skin conditions and can have a profound impact on wellbeing. There is limited guidance on how best to assess and support the mental health of this population, who are at risk of poor health outcomes. OBJECTIVES: To provide consensus-based recommendations on the assessment and monitoring of and support for mental health difficulties in CYP with skin conditions (affecting the skin, hair and nails); to address practical clinical implementation questions relating to consensus guidance; and to provide audit and research recommendations. METHODS: This set of recommendations was developed with reference to the AGREE II instrument. A systematic review and literature appraisal was carried out. A multidisciplinary consensus group was convened, with two virtual panel meetings held: an initial meeting to discuss the scope of the study, to review the current evidence and to identify areas for development; and a second meeting to agree on the content and wording of the recommendations. Recommendations were then circulated to stakeholders, following which amendments were made and agreed by email. RESULTS: The expert panel achieved consensus on 11 recommendations for healthcare workers managing CYP with skin conditions. A new patient-completed history-taking aid ('You and Your Skin') was developed and is being piloted. CONCLUSIONS: The recommendations focus on improved mental health assessments for CYP presenting with a skin condition, with clinical guidance and suggested screening measures included. Information on accessing psychological support for CYP, when required, is given, and recommendations for staff training in mental health and neurodiversity provided. Embedding a psychosocial approach within services treating CYP with skin disease should ensure that CYP with psychological needs are able to be identified, listened to, supported and treated. This is likely to improve health outcomes.


Asunto(s)
Dermatología , Salud Mental , Humanos , Niño , Adolescente , Personal de Salud , Consenso
2.
Behav Cogn Psychother ; 48(4): 419-431, 2020 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-32178754

RESUMEN

BACKGROUND: Despite their use in clinical practice, there is little evidence to support the use of therapist written goodbye letters as therapeutic tools. However, preliminary evidence suggests that goodbye letters may have benefits in the treatment of anorexia nervosa (AN). AIMS: This study aimed to examine whether therapist written goodbye letters were associated with improvements in body mass index (BMI) and eating disorder symptomology in patients with AN after treatment. METHOD: Participants were adults with AN (n = 41) who received The Maudsley Model of Anorexia Treatment for Adults (MANTRA) in a clinical trial evaluating two AN out-patient treatments. As part of MANTRA, therapists wrote goodbye letters to patients. A rating scheme was developed to rate letters for structure and quality. Linear regression analyses were used to examine associations between goodbye letter scores and outcomes after treatment. RESULTS: Higher quality letters and letters that adopted a more affirming stance were associated with greater improvements in BMI at 12 months. Neither the overall quality nor the style of goodbye letters were associated with improvements in BMI at 24 months or reductions in eating disorder symptomology at either 12 or 24 months. CONCLUSIONS: The results highlight the potential importance of paying attention to the overall quality of therapist written goodbye letters in the treatment of AN, and adopting an affirming stance.


Asunto(s)
Anorexia Nerviosa , Trastornos de Alimentación y de la Ingestión de Alimentos , Adulto , Atención Ambulatoria , Anorexia Nerviosa/terapia , Humanos , Pacientes Ambulatorios , Psicoterapia
3.
Eur Eat Disord Rev ; 26(3): 197-206, 2018 05.
Artículo en Inglés | MEDLINE | ID: mdl-29687578

RESUMEN

People with anorexia nervosa (AN) report socioemotional difficulties; however, measurement has been criticised for lacking ecological validity and the state or trait nature of difficulties remains unclear. Participants (n = 122) were recruited across 3 groups: people who are currently ill with AN (n = 40); people who recovered (RecAN, n = 18); healthy-control participants (n = 64). Participants completed clinical questionnaires and the Social Attribution Task. The Social Attribution Task involves describing an animation of moving shapes, scored for number of propositions offered, accuracy, and social relevance. Groups were compared cross-sectionally. Those with current AN were assessed prepsychological and postpsychological treatments. People with AN provided fewer propositions than other groups and fewer salient social attributions than healthy-control participants. Those who recovered scored intermediately and not significantly different from either group. Following treatment, people with AN demonstrated (nonsignificant) improvements, and no significance between group differences were observed. Findings suggest difficulties for people with AN in providing spontaneous social narrative and in identifying social salience.


Asunto(s)
Anorexia Nerviosa , Conducta Social , Adulto , Anorexia Nerviosa/psicología , Emociones , Humanos , Encuestas y Cuestionarios
4.
Int J Eat Disord ; 49(9): 874-82, 2016 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-27257748

RESUMEN

OBJECTIVE: Case formulation is a core component of many psychotherapies and formulation letters may provide an opportunity to enhance the therapeutic alliance and improve treatment outcomes. This study aimed to determine if formulation letters predict treatment satisfaction, session attendance, and symptom reductions in anorexia nervosa (AN). It was hypothesized that higher quality formulation letters would predict greater treatment satisfaction, a greater number of attended sessions, and greater improvement in eating disorder symptoms. METHOD: Patients were adult outpatients with AN (n = 46) who received Maudsley Anorexia Nervosa Treatment for Adults (MANTRA) in the context of a clinical trial. A Case Formulation Rating Scheme was used to rate letters for adherence to the MANTRA model and use of a collaborative, reflective, affirming stance. Analyses included linear regression and mixed models. RESULTS: Formulation letters that paid attention to the development of the AN predicted greater treatment acceptability ratings (p = 0.002). More reflective and respectful letters predicted greater reductions in Eating Disorder Examination scores (p = 0.003). DISCUSSION: Results highlight the potential significance of a particular style of written formulation as part of treatment for AN. Future research should examine applicability to other psychiatric disorders. © 2016 Wiley Periodicals, Inc.(Int J Eat Disord 2016; 49:874-882).


Asunto(s)
Anorexia Nerviosa/terapia , Psicoterapia/métodos , Adolescente , Adulto , Atención Ambulatoria/métodos , Anorexia Nerviosa/psicología , Índice de Masa Corporal , Comunicación , Femenino , Humanos , Masculino , Escritura Médica , Persona de Mediana Edad , Motivación , Pacientes Ambulatorios , Satisfacción del Paciente , Encuestas y Cuestionarios , Resultado del Tratamiento , Adulto Joven
5.
Int J Eat Disord ; 49(8): 793-800, 2016 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-27061709

RESUMEN

OBJECTIVE: This study reports follow-up data from a multicenter randomized controlled trial (n = 142) comparing the Maudsley Model of Anorexia Nervosa Treatment for Adults (MANTRA) with Specialist Supportive Clinical Management (SSCM) in outpatients with broadly defined anorexia nervosa (AN). At 12 months postrandomization, all patients had statistically significant improvements in body mass index (BMI), eating disorder (ED) symptomatology and other outcomes with no differences between groups. MANTRA was more acceptable to patients. The present study assessed whether gains were maintained at 24 months postrandomization. METHODS: Follow-up data at 24 months were obtained from 73.2% of participants. Outcome measures included BMI, ED symptomatology, distress, impairment, and additional service utilization during the study period. Outcomes were analyzed using linear mixed models. RESULTS: There were few differences between groups. In both treatment groups, improvements in BMI, ED symptomatology, distress levels, and clinical impairment were maintained or increased further. Estimated mean BMI change from baseline to 24 months was 2.16 kg/m(2) for SSCM and 2.25 kg/m(2) for MANTRA (effect sizes of 1.75 and 1.83, respectively). Most participants (83%) did not require any additional intensive treatments (e.g., hospitalization). Two SSCM patients became overweight through binge-eating. DISCUSSION: Both treatments have value as outpatient interventions for patients with AN. © 2016 Crown copyright. International Journal of Eating Disorders. (Int J Eat Disord 2016; 49:793-800).


Asunto(s)
Anorexia Nerviosa/terapia , Psicoterapia/métodos , Adulto , Atención Ambulatoria/métodos , Anorexia Nerviosa/psicología , Centros de Día/estadística & datos numéricos , Femenino , Estudios de Seguimiento , Hospitalización , Humanos , Masculino , Pacientes Ambulatorios , Resultado del Tratamiento
6.
Int J Eat Disord ; 48(1): 26-34, 2015 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-25363476

RESUMEN

OBJECTIVE: This study aimed to explore the neuro- and social-cognitive profile of a consecutive series of adult outpatients with anorexia nervosa (AN) when compared with widely available age and gender matched historical control data. The relationship between performance profiles, clinical characteristics, service utilization, and treatment adherence was also investigated. METHOD: Consecutively recruited outpatients with a broad diagnosis of AN (restricting subtype AN-R: n = 44, binge-purge subtype AN-BP: n = 33 or Eating Disorder Not Otherwise Specified-AN subtype EDNOS-AN: n = 23) completed a comprehensive set of neurocognitive (set-shifting, central coherence) and social-cognitive measures (Emotional Theory of Mind). Data were subjected to hierarchical cluster analysis and a discriminant function analysis. RESULTS: Three separate, meaningful clusters emerged. Cluster 1 (n = 45) showed overall average to high average neuro- and social- cognitive performance, Cluster 2 (n = 38) showed mixed performance characterized by distinct strengths and weaknesses, and Cluster 3 (n = 17) showed poor overall performance (Autism Spectrum disorder (ASD) like cluster). The three clusters did not differ in terms of eating disorder symptoms, comorbid features or service utilization and treatment adherence. A discriminant function analysis confirmed that the clusters were best characterized by performance in perseveration and set-shifting measures. DISCUSSION: The findings suggest that considerable neuro- and social-cognitive heterogeneity exists in patients with AN, with a subset showing ASD-like features. The value of this method of profiling in predicting longer term patient outcomes and in guiding development of etiologically targeted treatments remains to be seen.


Asunto(s)
Anorexia Nerviosa/psicología , Cognición , Adolescente , Adulto , Trastornos Generalizados del Desarrollo Infantil/psicología , Análisis por Conglomerados , Comorbilidad , Femenino , Humanos , Pruebas Neuropsicológicas , Adulto Joven
7.
Int J Eat Disord ; 45(5): 635-47, 2012 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-22684990

RESUMEN

OBJECTIVE: Dropout from treatment has serious implications for patients, clinicians, and researchers. The aim of this study was to examine rates of dropout from outpatient treatment for anorexia nervosa (AN) and critically examine the various definitions of dropout used. METHOD: A systematic review was conducted, including pharmacological and psychological interventions. All articles in PubMed, Web of Science, and the Cochrane Library were considered, and screened against a priori inclusion/exclusion criteria. Relationships between treatment outcome and dropout rate were examined across studies. RESULTS: Nineteen relevant studies were identified, with dropout rates ranging from 4.8% (family therapy) to 100% (dietary advice). In most cases, dropout was in the range of 20-40%. Definitions of dropout used varied widely. A significant negative correlation was found between rate of dropout and body mass index (BMI) at 1 year, but this did not remain significant when differences in BMI at baseline were taken into account. DISCUSSION: High rates of dropout from treatment for AN have serious implications for recovery, research, and the development of new treatments. A suggested reporting structure is proposed, with the aim of increasing the consistency of dropout reporting and facilitating greater understanding of this phenomenon.


Asunto(s)
Anorexia Nerviosa/terapia , Pacientes Ambulatorios/psicología , Pacientes Desistentes del Tratamiento/psicología , Atención Ambulatoria/estadística & datos numéricos , Anorexia Nerviosa/psicología , Humanos , Pacientes Ambulatorios/estadística & datos numéricos , Pacientes Desistentes del Tratamiento/estadística & datos numéricos , Resultado del Tratamiento
8.
Int J Eat Disord ; 45(3): 377-84, 2012 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-22212956

RESUMEN

OBJECTIVE: This study aimed to investigate theory of mind (ToM) in individuals with bulimia nervosa (BN), an area neglected by empirical research despite social functioning difficulties in this disorder and evidence of ToM deficits in people with anorexia nervosa (AN). METHOD: ToM was assessed in 48 BN and 34 Eating Disorder Not Otherwise Specified BN-type (EDNOS-BN) outpatients and 57 healthy controls (HCs) using the Reading the Mind in the Eyes and the Reading the Mind in the Films (RMF), an ecologically valid task novel to BN research. RESULTS: Overall performance in BN and EDNOS-BN groups was equivalent to HCs on both tasks. Individuals with BN had enhanced negative emotion recognition on the RMF. DISCUSSION: Individuals with AN and BN have distinct socio-cognitive profiles. Further research into social cognition is required to establish the link between interpersonal difficulties and psychopathology in people with BN.


Asunto(s)
Bulimia Nerviosa/psicología , Teoría de la Mente/fisiología , Ansiedad/psicología , Cognición/fisiología , Depresión/psicología , Femenino , Humanos , Masculino , Pruebas Neuropsicológicas , Escalas de Valoración Psiquiátrica , Encuestas y Cuestionarios
9.
Eur Eat Disord Rev ; 20(6): 502-9, 2012 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-22241653

RESUMEN

OBJECTIVE: Evidence suggests that poor emotional processing perpetuates anorexia nervosa (AN); however, emotional processing following recovery and interactions between aspects of processing remain unknown. This study examined beliefs about emotions, emotional tolerance and avoidance and emotion suppression to preserve relationships in recovered AN patients. It also explored whether beliefs about emotion are related to emotional avoidance. DESIGN: A cross-sectional between-groups design was employed. METHOD: Currently ill (n = 40), recovered AN patients (n = 24) and a sample of healthy controls (n = 48) completed measures of clinical and demographic background in addition to the Beliefs About Emotions, Distress Tolerance and Silencing the Self emotional processing questionnaires. RESULTS: Recovered and healthy control groups were comparable (except for higher externalised self-perception in recovered participants) and both had better emotional processing than current AN patients. Beliefs about emotions correlated with level of emotional avoidance. CONCLUSIONS: This study demonstrates functional levels of emotional processing following recovery from AN. It substantiates models proposing that maladaptive beliefs about emotions link to emotional avoidance and supports inclusion of these factors as treatment foci.


Asunto(s)
Adaptación Psicológica , Anorexia Nerviosa/psicología , Emociones/fisiología , Estudios Transversales , Cultura , Femenino , Humanos , Masculino , Autoimagen , Encuestas y Cuestionarios
10.
Int J Eat Disord ; 44(7): 661-4, 2011 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-21997430

RESUMEN

OBJECTIVE: This study examined the prevalence of irritable bowel syndrome (IBS) in patients with bulimia nervosa (BN), and the relationship between these disorders. METHOD: Sixty-four participants with a diagnosis of BN or a related condition were recruited from an outpatient eating disorders service. Questionnaire and interview measures were used to assess bulimic symptoms and attitudes, IBS symptoms, anxiety and depression. Cases of IBS were identified using the Manning criteria. RESULTS: There was a high prevalence of IBS in the patient group (68.8%), but IBS status was not predicted by any of the other variables measured. Patients who met criteria for IBS reported more frequent self-induced vomiting than those who did not (U = 256.0, p = 0.038). DISCUSSION: There is evidence of an high incidence of IBS in outpatients with BN, but the relationship between these conditions remains unclear. Future research should consider possible common risk factors.


Asunto(s)
Bulimia Nerviosa/epidemiología , Síndrome del Colon Irritable/epidemiología , Adulto , Índice de Masa Corporal , Comorbilidad , Femenino , Humanos , Síndrome del Colon Irritable/diagnóstico , Masculino , Pacientes Ambulatorios , Prevalencia , Factores de Riesgo , Índice de Severidad de la Enfermedad , Factores Sexuales , Encuestas y Cuestionarios
11.
J Behav Ther Exp Psychiatry ; 63: 28-35, 2019 06.
Artículo en Inglés | MEDLINE | ID: mdl-30639915

RESUMEN

BACKGROUND AND OBJECTIVES: It has been suggested that impaired attentional control (AC) promotes the use of maladaptive emotional regulation strategies, such as rumination, with subsequent increase in risk of depression. METHOD: This study examined this hypothesis in a healthy community sample. Questionnaire measures of depression, anxiety, rumination and self-reported AC (shifting and focusing) were used, as well as an attention performance task (Attention Network Task; ANT). RESULTS: While self-report and performance measures of AC were not significantly related, both depression and rumination were associated with reduced self-reported AC. Depression was specifically associated with poorer attentional shifting. Depression and brooding were also associated with better performance on the conflict component of the ANT. Importantly, the relationships of ANT conflict and self-reported AC to depression were mediated by brooding. LIMITATIONS: The current study used a community sample, and it is unclear if results would generalise to a clinical population. All measures were taken concurrently and so it is not possible to confidently ascertain causality or direction of effects. CONCLUSIONS: These results are consistent with the suggestion that impaired AC, particularly a narrow and inflexible attentional focus, may increase risk of depression by promoting ruminative thinking. The results highlight the importance of considering both self-report and performance measures of AC, as well as different components of attentional performance.


Asunto(s)
Atención , Depresión/diagnóstico , Depresión/psicología , Rumiación Cognitiva , Autocontrol , Adolescente , Adulto , Ansiedad/psicología , Femenino , Humanos , Masculino , Desempeño Psicomotor , Autoinforme , Adulto Joven
12.
J Affect Disord ; 256: 364-372, 2019 09 01.
Artículo en Inglés | MEDLINE | ID: mdl-31207560

RESUMEN

BACKGROUND: Depressive recurrence is highly prevalent and adds significantly to the burden of depressive disorder. Whilst some clinical predictors of recurrence have been clearly demonstrated (e.g. residual symptoms, previous episodes), the cognitive and psychological processes that may contribute to recurrence risk are less well established. In this study we examine whether cognitive flexibility deficits and rumination are related to recurrence in a remitted clinical sample. METHOD: We compared remitted patients with 2 or more previous depressive episodes (N = 69) to a matched group of healthy controls (N = 43). Cognitive flexibility was measured using the Internal Shift Task (IST) and a version of the Exogenous Cueing Task (ECT); rumination was assessed with the Ruminative Responses Scale. RESULTS: IST and ECT performance did not differ between remitted patients and controls. Remitted patients had higher levels of rumination than controls. Within the remitted patient group, faster disengagement from angry and happy faces on the ECT was predictive of shorter time to recurrence (hazard ratio for 1 standard deviation, (HRSD) = 0.563 [CI, 0.381-0.832], p = 0.004, (HRSD) = 0.561 [CI, 0.389-0.808], p = 0.002, respectively). Rumination predicted recurrence (HRSD = 1.526 [CI, 1.152-2.202]; p = 0.003) but was not related to emotional disengagement. LIMITATIONS: We had low power to detect small effects for the analysis within remitted patients. CONCLUSIONS: Whilst cognitive flexibility in remitted patients was not impaired relative to controls, rapid disengagement from emotional stimuli and rumination were independently associated with time to recurrence. Cognitive flexibility may be an important indicator of recurrence risk, and a target for interventions to reduce recurrence.


Asunto(s)
Atención , Trastorno Depresivo/psicología , Rumiación Cognitiva , Estudios de Casos y Controles , Emociones , Femenino , Humanos , Masculino , Procesos Mentales , Persona de Mediana Edad , Pruebas Neuropsicológicas , Prevalencia , Recurrencia , Inducción de Remisión
13.
Behav Res Ther ; 82: 38-49, 2016 07.
Artículo en Inglés | MEDLINE | ID: mdl-27203622

RESUMEN

Postnatal depression (PND) confers risk for a range of negative child developmental outcomes, at least in part through its impact on parenting behaviour. Whilst the behavioural effects of depression on parenting are well established, the cognitive mechanisms that may mediate this effect are less well understood. The current paper proposes that rumination may be a key cognitive mechanism through which parenting is affected in PND, and provides a systematic review of the existing literature on rumination in the context of perinatal depression. The review identifies ten relevant papers. Eight are questionnaire-based studies examining the role of rumination in predicting future depression and/or mother-infant relationship outcomes, such as bonding. Two are experimental studies examining the effects of induced rumination on parenting behaviours. The results of the review are discussed, and remaining questions highlighted. We then present a new theoretical model, developed specifically for the perinatal context, and informed by existing models of rumination and worry. Our cognitive model emphasises the relationship between rumination, cognitive biases and cognitive control, and the impact of these variables on infant cue processing and subsequent parenting responses. The model provides a potential framework for future work in this area, and to guide the development of treatment interventions.


Asunto(s)
Depresión Posparto/psicología , Pensamiento , Femenino , Humanos , Modelos Psicológicos , Relaciones Madre-Hijo/psicología , Responsabilidad Parental/psicología
14.
J Eat Disord ; 4: 2, 2016.
Artículo en Inglés | MEDLINE | ID: mdl-26865980

RESUMEN

BACKGROUND: This study is part of a series of process evaluations within the MOSAIC Trial (Maudsley Outpatient Study of Treatments for Anorexia Nervosa and Related Conditions). This randomised controlled trial (RCT) compared two psychological treatments, the Maudsley Model for Treatment of Adults with Anorexia Nervosa (MANTRA) and Specialist Supportive Clinical Management (SSCM) for adult outpatients with Anorexia Nervosa. The present process study integrates quantitative (treatment acceptability and credibility) and qualitative (written) feedback to evaluate patients' treatment experiences. METHOD: All 142 MOSAIC participants were asked to (a) rate treatment acceptability and credibility on visual analogue scales (VAS) at six and 12 months post-randomisation, and (b) provide written feedback regarding their views on their treatment at 12 months. Transcripts were first analysed thematically and then rated according to the global valence of feedback (positive, mixed/negative). RESULTS: 114/142 (80.3 %) MOSAIC participants provided VAS data and 82 (57.7 %) provided written feedback. At 12 months, MANTRA patients gave significantly higher acceptability and credibility ratings compared to SSCM patients. A significantly higher proportion of MANTRA patients provided written feedback. MANTRA patients also tended to write in more detail and to give globally more positive feedback when compared to individuals receiving SSCM. Qualitative themes suggest that patients experienced the two treatments differently in terms of characteristics and outcomes. CONCLUSIONS: This study highlights the benefits of incorporating qualitative and quantitative data into RCT process evaluations. MANTRA patients were more willing to express their views on treatment and generally felt more positively about this than those receiving SSCM.

15.
J Consult Clin Psychol ; 83(4): 796-807, 2015 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-25984803

RESUMEN

OBJECTIVE: Anorexia nervosa (AN) in adults has poor outcomes, and treatment evidence is limited. This study evaluated the efficacy and acceptability of a novel, targeted psychological therapy for AN (Maudsley Model of Anorexia Nervosa Treatment for Adults; MANTRA) compared with Specialist Supportive Clinical Management (SSCM). METHOD: One hundred forty-two outpatients with broadly defined AN (body mass index [BMI] ≤ 18.5 kg/m²) were randomly allocated to receive 20 to 30 weekly sessions (depending on clinical severity) plus add-ons (4 follow-up sessions, optional sessions with dietician and with carers) of MANTRA (n = 72) or SSCM (n = 70). Assessments were administered blind to treatment condition at baseline, 6 months, and 12 months after randomization. The primary outcome was BMI at 12 months. Secondary outcomes included eating disorders symptomatology, other psychopathology, neuro-cognitive and social cognition, and acceptability. Additional service utilization was also assessed. Outcomes were analyzed using linear mixed models. RESULTS: Both treatments resulted in significant improvements in BMI and reductions in eating disorders symptomatology, distress levels, and clinical impairment over time, with no statistically significant difference between groups at either 6 or 12 months. Improvements in neuro-cognitive and social-cognitive measures over time were less consistent. One SSCM patient died. Compared with SSCM, MANTRA patients rated their treatment as significantly more acceptable and credible at 12 months. There was no significant difference between groups in additional service consumption. CONCLUSIONS: Both treatments appear to have value as first-line outpatient interventions for patients with broadly defined AN. Longer term outcomes remain to be evaluated.


Asunto(s)
Atención Ambulatoria , Anorexia Nerviosa/terapia , Índice de Masa Corporal , Psicoterapia/métodos , Adolescente , Adulto , Manejo de la Enfermedad , Femenino , Humanos , Masculino , Pacientes Ambulatorios , Aceptación de la Atención de Salud , Autoinforme , Índice de Severidad de la Enfermedad , Resultado del Tratamiento
16.
J Autism Dev Disord ; 44(9): 2127-36, 2014 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-24643578

RESUMEN

A systematic review was conducted to examine the efficacy of a range of treatments for autistic catatonia. The review identified 22 relevant papers, reporting a total of 28 cases including both adult and paediatric patients. Treatment methods included electroconvulsive therapy (ECT), medication, behavioural and sensory interventions. Quality assessment found the standard of the existing literature to be generally poor, with particular limitations in treatment description and outcome measurement. There is some limited evidence to support the use of ECT, high dose lorazepam and behavioural interventions for people with autistic catatonia. However, there is a need for controlled, high-quality trials. Reporting of side effects and adverse events should also be improved, in order to better evaluate the safety of these treatments.


Asunto(s)
Catatonia/terapia , Trastornos Generalizados del Desarrollo Infantil/fisiopatología , Terapia Electroconvulsiva , Adulto , Catatonia/fisiopatología , Niño , Terapia Electroconvulsiva/efectos adversos , Humanos , Masculino
17.
J Eat Disord ; 1: 43, 2013.
Artículo en Inglés | MEDLINE | ID: mdl-24999421

RESUMEN

BACKGROUND: This study aimed to assess differences in Quality of Life (QoL) across eating disorder (ED) diagnoses, and to examine the relationship of QoL to specific clinical features. RESULTS: 199 patients with a diagnosed ED completed the Clinical Impairment Assessment (CIA) [Cognitive Behavior Therapy and Eating Disorders, 315-318, 2008] and the Eating Disorders Examination (EDE) [Int J Eat Disord 6:1-8]. Differences between diagnostic groups were examined, as were differences between restrictive and binge-purge subtypes. CIA scores and EDE scores were positively correlated and higher in groups with binge-purge behaviours. CIA scores were not correlated with BMI, illness duration or frequency of bingeing/purging behaviours, except in the binge-purge AN group, where CIA scores negatively correlated with BMI. CONCLUSIONS: Patients with EDs have poor QoL and impairment increases with illness severity. Patients with binge/purge diagnoses are particularly impaired. It remains unclear which clinical features best predict the degree of impairment experienced by patients with EDs.

18.
Trials ; 14: 160, 2013 May 30.
Artículo en Inglés | MEDLINE | ID: mdl-23721562

RESUMEN

BACKGROUND: Anorexia nervosa (AN) is a biologically based serious mental disorder with high levels of mortality and disability, physical and psychological morbidity and impaired quality of life. AN is one of the leading causes of disease burden in terms of years of life lost through death or disability in young women. Psychotherapeutic interventions are the treatment of choice for AN, but the results of psychotherapy depend critically on the stage of the illness. The treatment response in adults with a chronic form of the illness is poor and drop-out from treatment is high. Despite the seriousness of the disorder the evidence-base for psychological treatment of adults with AN is extremely limited and there is no leading treatment. There is therefore an urgent need to develop more effective treatments for adults with AN. The aim of the Maudsley Outpatient Study of Treatments for Anorexia Nervosa and Related Conditions (MOSAIC) is to evaluate the efficacy and cost effectiveness of two outpatient treatments for adults with AN, Specialist Supportive Clinical Management (SSCM) and the Maudsley Model of Treatment for Adults with Anorexia Nervosa (MANTRA). METHODS/DESIGN: 138 patients meeting the inclusion criteria are randomly assigned to one of the two treatment groups (MANTRA or SSCM). All participants receive 20 once-weekly individual therapy sessions (with 10 extra weekly sessions for those who are severely ill) and four follow-up sessions with monthly spacing thereafter. There is also optional access to a dietician and extra sessions involving a family member or a close other. Body weight, eating disorder- related symptoms, neurocognitive and psychosocial measures, and service use data are measured during the course of treatment and across a one year follow up period. The primary outcome measure is body mass index (BMI) taken at twelve months after randomization. DISCUSSION: This multi-center study provides a large sample size, broad inclusion criteria and a follow-up period. However, the study has to contend with difficulties directly related to running a large multi-center randomized controlled trial and the psychopathology of AN. These issues are discussed.


Asunto(s)
Atención Ambulatoria , Anorexia Nerviosa/terapia , Trastornos de Alimentación y de la Ingestión de Alimentos/terapia , Servicios de Salud Mental , Proyectos de Investigación , Adulto , Atención Ambulatoria/economía , Anorexia Nerviosa/diagnóstico , Anorexia Nerviosa/economía , Anorexia Nerviosa/psicología , Índice de Masa Corporal , Protocolos Clínicos , Análisis Costo-Beneficio , Dietética , Terapia Familiar , Trastornos de Alimentación y de la Ingestión de Alimentos/diagnóstico , Trastornos de Alimentación y de la Ingestión de Alimentos/economía , Trastornos de Alimentación y de la Ingestión de Alimentos/psicología , Objetivos , Conductas Relacionadas con la Salud , Costos de la Atención en Salud , Conocimientos, Actitudes y Práctica en Salud , Humanos , Londres , Servicios de Salud Mental/economía , Entrevista Motivacional , Estado Nutricional , Educación del Paciente como Asunto , Tamaño de la Muestra , Factores de Tiempo , Resultado del Tratamiento , Aumento de Peso
19.
J Health Psychol ; 17(3): 399-408, 2012 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-21859799

RESUMEN

The study was designed to extend our understanding of illness perceptions in patients with bulimia nervosa (BN). Seventy-eight participants with BN or BN-type Eating Disorder Not Otherwise Specified (EDNOS-BN) completed the Revised Illness Perception Questionnaire (IPQ-R) (Moss-Morris et al., 2002). Clinical variables were also assessed. Participants experienced their ED as chronic, with serious consequences and high associated levels of anxiety and depression. The disorder was attributed primarily to psychological causes. The results indicate the perceived severity of BN, and high level of associated distress. These findings highlight the potential for targeting illness perceptions in treatment.


Asunto(s)
Actitud Frente a la Salud , Bulimia Nerviosa/psicología , Enfermedad/psicología , Adolescente , Adulto , Bulimia Nerviosa/etiología , Femenino , Humanos , Masculino , Persona de Mediana Edad , Percepción , Escalas de Valoración Psiquiátrica , Encuestas y Cuestionarios , Adulto Joven
20.
J Behav Ther Exp Psychiatry ; 43(2): 758-64, 2012 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-22104657

RESUMEN

BACKGROUND AND OBJECTIVES: Involuntary autobiographical memories that spring unbidden into conscious awareness form part of everyday experience. In psychopathology, involuntary memories can be associated with significant distress. However, the cognitive mechanisms associated with the development of involuntary memories require further investigation and understanding. Since involuntary autobiographical memories are image-based, we tested predictions that visuospatial (but not other) established cognitive tasks could disrupt their consolidation when completed post-encoding. METHODS: In Experiment 1, participants watched a stressful film then immediately completed a visuospatial task (complex pattern tapping), a control-task (verbal task) or no-task. Involuntary memories of the film were recorded for 1-week. In Experiment 2, the cognitive tasks were administered 30-min post-film. RESULTS: Compared to both control and no-task conditions, completing a visuospatial task post-film reduced the frequency of later involuntary memories (Expts 1 and 2) but did not affect voluntary memory performance on a recognition task (Expt 2). LIMITATIONS: Voluntary memory was assessed using a verbal recognition task and a broader range of memory tasks could be used. The relative difficulty of the cognitive tasks used was not directly established. CONCLUSIONS: An established visuospatial task after encoding of a stressful experience selectively interferes with sensory-perceptual information processing and may therefore prevent the development of involuntary autobiographical memories.


Asunto(s)
Imágenes en Psicoterapia/métodos , Memoria Episódica , Películas Cinematográficas , Pruebas Neuropsicológicas , Trastornos por Estrés Postraumático , Adolescente , Adulto , Factores de Edad , Análisis de Varianza , Femenino , Humanos , Imaginación , Masculino , Persona de Mediana Edad , Dimensión del Dolor , Estimulación Luminosa/efectos adversos , Escalas de Valoración Psiquiátrica , Percepción Espacial , Trastornos por Estrés Postraumático/etiología , Trastornos por Estrés Postraumático/psicología , Trastornos por Estrés Postraumático/rehabilitación , Adulto Joven
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