Detalles de la búsqueda
1.
Targeting inflammation: a potential approach for the treatment of depression.
Metab Brain Dis
; 38(1): 45-59, 2023 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-36239867
2.
QCM-4, a 5-HT3 receptor antagonist ameliorates plasma HPA axis hyperactivity, leptin resistance and brain oxidative stress in depression and anxiety-like behavior in obese mice.
Biochem Biophys Res Commun
; 456(1): 74-9, 2015 Jan 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-25446100
3.
Anxiolytic-like effect of N-n-butyl-3-methoxyquinoxaline-2-carboxamide (60) in experimental mouse models of anxiety.
Indian J Exp Biol
; 51(7): 510-4, 2013 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-23898549
4.
Anti-depressant like activity of N-n-butyl-3-methoxyquinoxaline-2-carboxamide (6o) a 5-HT3 receptor antagonist.
Indian J Exp Biol
; 51(6): 435-43, 2013 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-23926691
5.
Ligand-based design, synthesis, and pharmacological evaluation of 3-Methoxyquinoxalin-2-carboxamides as structurally novel serotonin type-3 receptor antagonists.
Arch Pharm (Weinheim)
; 345(9): 687-94, 2012 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-22674774
6.
Antidepressant and anxiolytic-like effects of 4n, a novel 5-HT3 receptor antagonist using behaviour based rodent models.
Indian J Exp Biol
; 50(9): 625-32, 2012 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-23140020
7.
Discovery of new anti-depressants from structurally novel 5-HT3 receptor antagonists: design, synthesis and pharmacological evaluation of 3-ethoxyquinoxalin-2-carboxamides.
Bioorg Med Chem Lett
; 21(4): 1253-6, 2011 Feb 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-21256009
8.
Quinoxalin-2-carboxamides: synthesis and pharmacological evaluation as serotonin type-3 (5-HT3) receptor antagonists.
J Enzyme Inhib Med Chem
; 26(5): 610-5, 2011 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-21222509
9.
Anti-depressant-like activity of a novel serotonin type-3 (5-HT3) receptor antagonist in rodent models of depression.
Indian J Exp Biol
; 49(8): 619-26, 2011 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-21870430
10.
5-HT3 receptor antagonism a potential therapeutic approach for the treatment of depression and other disorders.
Curr Neuropharmacol
; 19(9): 1545-1559, 2021.
Artículo
en Inglés
| MEDLINE | ID: mdl-33059577
11.
Design, synthesis and structure-activity relationship of novel quinoxalin-2-carboxamides as 5-HT3 receptor antagonists for the management of depression.
Bioorg Med Chem Lett
; 20(22): 6773-6, 2010 Nov 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-20851599
12.
Construction of a novel quinoxaline as a new class of Nrf2 activator.
BMC Chem
; 13(1): 117, 2019 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-31572984
13.
Novel 5-HT3 receptor antagonist QCM-4 attenuates depressive-like phenotype associated with obesity in high-fat-diet-fed mice.
Psychopharmacology (Berl)
; 234(7): 1165-1179, 2017 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-28238069
14.
Neuropharmacological evaluation of a novel 5-HT3 receptor antagonist (4-benzylpiperazin-1-yl)(3-methoxyquinoxalin-2-yl) methanone (6g) on lipopolysaccharide-induced anxiety models in mice.
J Basic Clin Physiol Pharmacol
; 28(2): 101-106, 2017 Mar 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-27664773
15.
Neuropharmacological and neurochemical evaluation of N-n-propyl-3-ethoxyquinoxaline-2-carboxamide (6n): a novel serotonergic 5-HT3 receptor antagonist for co-morbid antidepressant- and anxiolytic-like potential using traumatic brain injury model in rats.
J Basic Clin Physiol Pharmacol
; 28(2): 93-100, 2017 Mar 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-27662644
16.
Antidepressant-like effect of a novel 5-HT3 receptor antagonist N-(benzo[d] thiazol-2-yl)-3-ethoxyquinoxalin-2-carboxamide 6k using rodents behavioral battery tests.
J Pharmacol Pharmacother
; 5(3): 197-202, 2014 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-25210400
17.
QCM-4 a novel 5-HT3 antagonist attenuates the behavioral and biochemical alterations on chronic unpredictable mild stress model of depression in Swiss albino mice.
J Pharm Pharmacol
; 66(1): 122-32, 2014 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-24180368
18.
Neuropharmacological effect of novel 5-HT3 receptor antagonist, N-n-propyl-3-ethoxyquinoxaline-2-carboxamide (6n) on chronic unpredictable mild stress-induced molecular and cellular response: Behavioural and biochemical evidences.
Pharmacol Rep
; 66(5): 804-10, 2014 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-25149984
19.
QCM-4, a serotonergic type 3 receptor modulator attenuates depression co-morbid with obesity in mice: an approach based on behavioral and biochemical investigations.
Eur J Pharmacol
; 740: 611-8, 2014 Oct 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-24973694
20.
Protective effects of a novel 5-HT3 receptor antagonist, N-n-butyl-3-methoxy quinoxaline-2-carboxamide (6o) against chronic unpredictable mild stress-induced behavioral changes and biochemical alterations.
Pharmacol Biochem Behav
; 122: 234-9, 2014 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-24769308