1.
Yao Xue Xue Bao
; 50(6): 658-67, 2015 Jun.
Artículo
en Zh
| MEDLINE
| ID: mdl-26521434
RESUMEN
Estrogen receptors (ERs) are members of nuclear receptors and related to several diseases such as cancer, inflammation and osteoporosis. ERs have two forms, ERα and ERß, which have different functions and organism distributions. Compounds selectively targeting ERß can regulate important physiological functions and avoid the side effects caused by targeting ERα. Therefore, selective ERß ligands have received considerable research interest in recent years. In this article, different kinds of selective ERß ligands were summarized and their structure-activity relationships were also analyzed.