RESUMEN
INTRODUCTION: The purpose of this study was to characterize the incidence of growth disturbance following intra-articular distal radius fractures in skeletally immature patients and to assess early radiographic and functional outcomes. METHODS: A retrospective investigation of pediatric patients with intra-articular distal radius fractures between 1997 and 2012 at a single institution was performed. Pathologic fractures and fractures in patients with closed physes were excluded. In total, 28 patients (24 males, 4 females), with a mean age of 13.8 years and mean follow-up of 31.7 months, met inclusion criteria. Fractures were categorized according to the Salter-Harris classification, and all radiographs were assessed for evidence of physeal disturbance. Information regarding treatment and early clinical results were obtained from a medical record review. Functional outcomes using the Disabilities of the Arm, Shoulder, and Hand (DASH) and Modified Mayo Wrist Score (MMWS) were collected. Fisher exact test was used to compare the incidence of physeal arrest in the study population to previously published rates of physeal arrest in extra-articular fractures involving the distal radius. Because the data were not parametrically distributed, the Mann-Whitney-Wilcoxon test was used to compare those who did and did not develop physeal arrest. RESULTS: Of the 28 patients, 9 (32%) sustained Salter-Harris III fractures and 19 (68%) sustained Salter-Harris IV fractures. Growth disturbance occurred in 12 (43%) patients, comprised of 3 Salter-Harris III fractures and 9 Salter-Harris IV fractures; 7 of these patients underwent surgical intervention to address deformity. All 4 children age 10 years or younger had growth arrests that underwent subsequent procedures for a skeletal rebalancing of the wrist. No significant differences in DASH or MMWS were seen in the short term between patients who did or did not have physeal arrest. CONCLUSIONS: Intra-articular distal radius fractures in skeletally immature patients have a considerably higher rate of physeal growth arrest than extra-articular physeal fractures. Following acute management aimed at restoring and preserving anatomic physeal and articular alignment, follow-up radiographs should be obtained to evaluate for physeal arrest in skeletally immature children. Patients and families should be counseled regarding the high rate of growth disturbance and the potential need for deformity correction in the future, particularly in younger children. LEVEL OF EVIDENCE: IV-case series.
Asunto(s)
Placa de Crecimiento/fisiopatología , Fracturas del Radio/fisiopatología , Radio (Anatomía)/fisiopatología , Fracturas de Salter-Harris/fisiopatología , Traumatismos de la Muñeca/fisiopatología , Adolescente , Niño , Femenino , Humanos , Masculino , Radiografía , Radio (Anatomía)/cirugía , Fracturas del Radio/diagnóstico por imagen , Fracturas del Radio/cirugía , Estudios Retrospectivos , Fracturas de Salter-Harris/diagnóstico por imagen , Articulación de la MuñecaAsunto(s)
Anticuerpos Monoclonales , Protocolos de Quimioterapia Combinada Antineoplásica , Trasplante de Células Madre Hematopoyéticas , Retinoblastoma , Preescolar , Humanos , Anticuerpos Monoclonales/uso terapéutico , Anticuerpos Monoclonales/administración & dosificación , Protocolos de Quimioterapia Combinada Antineoplásica/uso terapéutico , Terapia Combinada , Inmunoterapia/métodos , Recurrencia Local de Neoplasia/tratamiento farmacológico , Recurrencia Local de Neoplasia/patología , Neoplasias de la Retina/patología , Neoplasias de la Retina/tratamiento farmacológico , Neoplasias de la Retina/terapia , Retinoblastoma/tratamiento farmacológico , Retinoblastoma/terapia , Retinoblastoma/patología , Trombopoyetina/uso terapéutico , Trasplante AutólogoRESUMEN
BACKGROUND: Malunion is the most common complication of distal radius fracture. It has previously been demonstrated that there is a correlation between the quality of anatomical correction and overall wrist function. However, surgical correction can be difficult because of the often complex anatomy associated with this condition. Computer assisted surgical planning, combined with patient-specific surgical guides, has the potential to improve pre-operative understanding of patient anatomy as well as intra-operative accuracy. For patients with malunion of the distal radius fracture, this technology could significantly improve clinical outcomes that largely depend on the quality of restoration of normal anatomy. Therefore, the objective of this study is to compare patient outcomes after corrective osteotomy for distal radius malunion with and without preoperative computer-assisted planning and peri-operative patient-specific surgical guides. METHODS/DESIGN: This study is a multi-center randomized controlled trial of conventional planning versus computer-assisted planning for surgical correction of distal radius malunion. Adult patients with extra-articular malunion of the distal radius will be invited to enroll in our study. After providing informed consent, subjects will be randomized to two groups: one group will receive corrective surgery with conventional preoperative planning, while the other will receive corrective surgery with computer-assisted pre-operative planning and peri-operative patient specific surgical guides. In the computer-assisted planning group, a CT scan of the affected forearm as well as the normal, contralateral forearm will be obtained. The images will be used to construct a 3D anatomical model of the defect and patient-specific surgical guides will be manufactured. Outcome will be measured by DASH and PRWE scores, grip strength, radiographic measurements, and patient satisfaction at 3, 6, and 12 months postoperatively. DISCUSSION: Computer-assisted surgical planning, combined with patient-specific surgical guides, is a powerful new technology that has the potential to improve the accuracy and consistency of orthopaedic surgery. To date, the role of this technology in upper extremity surgery has not been adequately investigated, and it is unclear whether its use provides any significant clinical benefit over traditional preoperative imaging protocols. Our study will represent the first randomized controlled trial investigating the use of computer assisted surgery in corrective osteotomy for distal radius malunions. TRIAL REGISTRATION: NCT01193010.
Asunto(s)
Fracturas Mal Unidas/cirugía , Osteotomía/métodos , Fracturas del Radio/cirugía , Cirugía Asistida por Computador/métodos , Adulto , Fracturas Mal Unidas/diagnóstico por imagen , Humanos , Evaluación de Resultado en la Atención de Salud , Fracturas del Radio/diagnóstico por imagen , Tomografía Computarizada por Rayos X , Resultado del TratamientoRESUMEN
BACKGROUND: In vitro data suggest that injury to the posterior cruciate ligament stresses the posterolateral structures of the knee, placing them at greater risk of secondary injury. However, it is not known how isolated posterior cruciate ligament deficiency affects these soft tissue stabilizers of the knee joint in vivo. HYPOTHESIS: Posterior cruciate ligament deficiency will alter the apparent length patterns of the lateral collateral ligament (LCL) and popliteus. STUDY DESIGN: Controlled laboratory study. METHODS: The apparent length changes in the lateral collateral ligament and popliteus muscle-tendon unit during weightbearing knee flexion were studied in 14 patients with isolated, unilateral posterior cruciate ligament deficiency using magnetic resonance imaging, dual-orthogonal fluoroscopy, and 3-dimensional modeling. Data of the injured and uninjured contralateral sides were compared. RESULTS: Posterior cruciate ligament deficiency caused significant increases in the apparent length of both posterolateral structures (P < .05). The differences between injured and uninjured contralateral side were greatest at 120 degrees of knee flexion in the lateral collateral ligament (48.2 +/- 6.1 mm and 51.6 +/- 6.1 mm, respectively) and at 30 degrees of knee flexion in the popliteus (101.2 +/- 9.3 mm and 110.4 +/- 10.2 mm, respectively). CONCLUSION: Deficiency of the posterior cruciate ligament alters the length patterns of posterolateral structures in vivo and might place them at greater risk of secondary injury. CLINICAL RELEVANCE: Reestablishment of normal kinematics after posterior cruciate ligament injury is critical for restoring normal function of posterolateral structures of the knee.