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Int J Infect Dis ; 104: 276-281, 2021 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-33359947

RESUMEN

OBJECTIVE: To compare the prevalence of hepatitis B virus (HBV) in pregnant women with and without human immunodeficiency virus (HIV) in Jos, Nigeria. METHODS: This comparative cross-sectional study of pregnant women was undertaken between 1 November 2017 and 30 April 2018. Informed consent was obtained, demographic data and predictors for HBV were collected, and all women were screened for HIV and HBV. Descriptive statistics and multivariate analyses using STATA Version 15 were performed. RESULTS: Of 3238 women enrolled, 12.6% and 7.2% of those with and without HIV had HBV, respectively (P = 0.01). Women with HIV, higher parity [adjusted odds ratio (aOR) 0.68, P < 0.01], lower gestational age (aOR 1.04, P < 0.01) and without prior HBV vaccination (aOR 0.40, P < 0.01) were significantly more likely to have HBV infection. CONCLUSIONS: Among pregnant women, the prevalence of HBV was higher among those with HIV. Predictors of HBV included being multigravida or grand-multigravida, registration for antenatal care before 20 weeks of gestation, and no prior HBV vaccination. In settings with endemic HBV and HIV, integration of effective HBV and HIV prevention services could greatly decrease the transmission and prevalence of HBV.


Asunto(s)
Infecciones por VIH/epidemiología , Hepatitis B/epidemiología , Complicaciones Infecciosas del Embarazo/epidemiología , Adolescente , Adulto , Coinfección/virología , Estudios Transversales , Femenino , Virus de la Hepatitis B , Humanos , Análisis Multivariante , Nigeria/epidemiología , Embarazo , Complicaciones Infecciosas del Embarazo/virología , Mujeres Embarazadas , Atención Prenatal , Prevalencia , Factores de Riesgo , Adulto Joven
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