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1.
Int J Mol Sci ; 25(13)2024 Jul 01.
Artículo en Inglés | MEDLINE | ID: mdl-39000363

RESUMEN

Foods enriched with insects can potentially prevent several health disorders, including cardiovascular diseases, by reducing inflammation and improving antioxidant status. In this study, Tenebrio molitor and Gryllus assimilis were selected to determine the effect on the development of atherosclerosis in ApoE/LDLR-/- mice. Animals were fed AIN-93G-based diets (control) with 10% Tenebrio molitor (TM) and 10% Gryllus assimilis (GA) for 8 weeks. The nutritional value as well as antioxidant activity of selected insects were determined. The lipid profile, liver enzyme activity, and the fatty acid composition of liver and adipose tissue of model mice were evaluated. Quantitative analysis of atherosclerotic lesions in the entire aorta was performed using the en face method, and for aortic roots, the cross-section method was used. The antioxidant status of the GA cricket was significantly higher compared to the TM larvae. The results showed that the area of atherosclerosis (en face method) was not significantly different between groups. Dietary GA reduced plaque formation in the aortic root; additionally, significant differences were observed in sections at 200 and 300 µm compared to other groups. Furthermore, liver enzyme ALT activity was lower in insect-fed groups compared to the control group. The finding suggests that a diet containing edible insect GA potentially prevents atherosclerotic plaque development in the aortic root, due to its high antioxidant activity.


Asunto(s)
Apolipoproteínas E , Aterosclerosis , Receptores de LDL , Animales , Aterosclerosis/patología , Aterosclerosis/metabolismo , Ratones , Receptores de LDL/genética , Receptores de LDL/metabolismo , Apolipoproteínas E/deficiencia , Apolipoproteínas E/genética , Insectos Comestibles , Ratones Noqueados , Hígado/metabolismo , Hígado/patología , Antioxidantes/metabolismo , Masculino , Tenebrio , Dieta , Aorta/patología , Aorta/metabolismo , Modelos Animales de Enfermedad , Alimentación Animal , Placa Aterosclerótica/patología , Placa Aterosclerótica/metabolismo , Gryllidae
2.
Food Sci Nutr ; 11(12): 7534-7545, 2023 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-38107123

RESUMEN

Every living thing requires food to survive. Clean, fresh, and healthy foods are important to human health. Today, food is affected by various counterfeits. Adulteration of food is the intentional deterioration of the quality of food offered for sale by either the addition or substitution of an inferior substance or by the omission of a valuable ingredient. Economically motivated adulteration is the intentional adulteration of food for financial gain, and has enormous public health implications, making it an important issue in food science. Almost every food, including milk and dairy products, fats and oils, fruits and vegetables, grain foods, coffee, tea, honey, etc., is susceptible to adulteration. It is difficult to find food that is free from adulteration. Consumption of adulterated food contributes to numerous diseases in society, ranging from mild to life threatening. Therefore, detection of adulteration in food is essential to ensure the safety of the food we consume. To provide consumers with food that is free of adulterants, various detection methods such as physical, chemical, biochemical, and molecular techniques are used to identify adulterants in food. This review aims to provide up-to-date information on food adulteration, its impact on health, and the analytical techniques used to detect adulteration in food.

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