Búsqueda | Portal de Búsqueda de la BVS

1.

Energy-driven genome regulation by ATP-dependent chromatin remodellers.

Eustermann, Sebastian; Patel, Avinash B; Hopfner, Karl-Peter; He, Yuan; Korber, Philipp.

Nat Rev Mol Cell Biol ; 25(4): 309-332, 2024 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-38081975

2.

Lysosomal endonuclease RNase T2 and PLD exonucleases cooperatively generate RNA ligands for TLR7 activation.

Bérouti, Marleen; Lammens, Katja; Heiss, Matthias; Hansbauer, Larissa; Bauernfried, Stefan; Stöckl, Jan; Pinci, Francesca; Piseddu, Ignazio; Greulich, Wilhelm; Wang, Meiyue; Jung, Christophe; Fröhlich, Thomas; Carell, Thomas; Hopfner, Karl-Peter; Hornung, Veit.

Immunity ; 2024 Apr 26.

Artículo en Inglés | MEDLINE | ID: mdl-38697119

3.

Molecular mechanisms and cellular functions of cGAS-STING signalling.

Hopfner, Karl-Peter; Hornung, Veit.

Nat Rev Mol Cell Biol ; 21(9): 501-521, 2020 09.

Artículo en Inglés | MEDLINE | ID: mdl-32424334

4.

Cryo-EM structure of the Mre11-Rad50-Nbs1 complex reveals the molecular mechanism of scaffolding functions.

Rotheneder, Matthias; Stakyte, Kristina; van de Logt, Erik; Bartho, Joseph D; Lammens, Katja; Fan, Yilan; Alt, Aaron; Kessler, Brigitte; Jung, Christophe; Roos, Wynand P; Steigenberger, Barbara; Hopfner, Karl-Peter.

Mol Cell ; 83(2): 167-185.e9, 2023 Jan 19.

Artículo en Inglés | MEDLINE | ID: mdl-36577401

5.

Viral unmasking of cellular 5S rRNA pseudogene transcripts induces RIG-I-mediated immunity.

Chiang, Jessica J; Sparrer, Konstantin M J; van Gent, Michiel; Lässig, Charlotte; Huang, Teng; Osterrieder, Nikolaus; Hopfner, Karl-Peter; Gack, Michaela U.

Nat Immunol ; 19(1): 53-62, 2018 Jan.

Artículo en Inglés | MEDLINE | ID: mdl-29180807

6.

Structural mechanism of endonucleolytic processing of blocked DNA ends and hairpins by Mre11-Rad50.

Gut, Fabian; Käshammer, Lisa; Lammens, Katja; Bartho, Joseph D; Boggusch, Anna-Maria; van de Logt, Erik; Kessler, Brigitte; Hopfner, Karl-Peter.

Mol Cell ; 82(18): 3513-3522.e6, 2022 09 15.

Artículo en Inglés | MEDLINE | ID: mdl-35987200

7.

Structure and subunit topology of the INO80 chromatin remodeler and its nucleosome complex.

Tosi, Alessandro; Haas, Caroline; Herzog, Franz; Gilmozzi, Andrea; Berninghausen, Otto; Ungewickell, Charlotte; Gerhold, Christian B; Lakomek, Kristina; Aebersold, Ruedi; Beckmann, Roland; Hopfner, Karl-Peter.

Cell ; 154(6): 1207-19, 2013 Sep 12.

Artículo en Inglés | MEDLINE | ID: mdl-24034245

8.

Sequence-specific activation of the DNA sensor cGAS by Y-form DNA structures as found in primary HIV-1 cDNA.

Herzner, Anna-Maria; Hagmann, Cristina Amparo; Goldeck, Marion; Wolter, Steven; Kübler, Kirsten; Wittmann, Sabine; Gramberg, Thomas; Andreeva, Liudmila; Hopfner, Karl-Peter; Mertens, Christina; Zillinger, Thomas; Jin, Tengchuan; Xiao, Tsan Sam; Bartok, Eva; Coch, Christoph; Ackermann, Damian; Hornung, Veit; Ludwig, Janos; Barchet, Winfried; Hartmann, Gunther; Schlee, Martin.

Nat Immunol ; 16(10): 1025-33, 2015 Oct.

Artículo en Inglés | MEDLINE | ID: mdl-26343537

9.

Measuring DNA mechanics on the genome scale.

Basu, Aakash; Bobrovnikov, Dmitriy G; Qureshi, Zan; Kayikcioglu, Tunc; Ngo, Thuy T M; Ranjan, Anand; Eustermann, Sebastian; Cieza, Basilio; Morgan, Michael T; Hejna, Miroslav; Rube, H Tomas; Hopfner, Karl-Peter; Wolberger, Cynthia; Song, Jun S; Ha, Taekjip.

Nature ; 589(7842): 462-467, 2021 01.

Artículo en Inglés | MEDLINE | ID: mdl-33328628

10.

Mechanism of DNA End Sensing and Processing by the Mre11-Rad50 Complex.

Käshammer, Lisa; Saathoff, Jan-Hinnerk; Lammens, Katja; Gut, Fabian; Bartho, Joseph; Alt, Aaron; Kessler, Brigitte; Hopfner, Karl-Peter.

Mol Cell ; 76(3): 382-394.e6, 2019 11 07.

Artículo en Inglés | MEDLINE | ID: mdl-31492634

11.

Rad50-CARD9 interactions link cytosolic DNA sensing to IL-1ß production.

Roth, Susanne; Rottach, Andrea; Lotz-Havla, Amelie S; Laux, Verena; Muschaweckh, Andreas; Gersting, Søren W; Muntau, Ania C; Hopfner, Karl-Peter; Jin, Lei; Vanness, Katelynd; Petrini, John H J; Drexler, Ingo; Leonhardt, Heinrich; Ruland, Jürgen.

Nat Immunol ; 15(6): 538-45, 2014 Jun.

Artículo en Inglés | MEDLINE | ID: mdl-24777530

12.

The Mre11:Rad50 structure shows an ATP-dependent molecular clamp in DNA double-strand break repair.

Lammens, Katja; Bemeleit, Derk J; Möckel, Carolin; Clausing, Emanuel; Schele, Alexandra; Hartung, Sophia; Schiller, Christian B; Lucas, Maria; Angermüller, Christof; Söding, Johannes; Strässer, Katja; Hopfner, Karl-Peter.

Cell ; 145(1): 54-66, 2011 Apr 01.

Artículo en Inglés | MEDLINE | ID: mdl-21458667

13.

Structural basis for sequestration and autoinhibition of cGAS by chromatin.

Michalski, Sebastian; de Oliveira Mann, Carina C; Stafford, Che A; Witte, Gregor; Bartho, Joseph; Lammens, Katja; Hornung, Veit; Hopfner, Karl-Peter.

Nature ; 587(7835): 678-682, 2020 11.

Artículo en Inglés | MEDLINE | ID: mdl-32911480

14.

Nuclear cGAS: guard or prisoner?

de Oliveira Mann, Carina C; Hopfner, Karl-Peter.

EMBO J ; 40(16): e108293, 2021 08 16.

Artículo en Inglés | MEDLINE | ID: mdl-34250619

15.

DNA double-strand breaks come into focus.

Hopfner, Karl-Peter.

Cell ; 139(1): 25-7, 2009 Oct 02.

Artículo en Inglés | MEDLINE | ID: mdl-19804750

16.

Structural basis for ATP-dependent chromatin remodelling by the INO80 complex.

Eustermann, Sebastian; Schall, Kevin; Kostrewa, Dirk; Lakomek, Kristina; Strauss, Mike; Moldt, Manuela; Hopfner, Karl-Peter.

Nature ; 556(7701): 386-390, 2018 04.

Artículo en Inglés | MEDLINE | ID: mdl-29643509

17.

RPA Mediates Recruitment of MRX to Forks and Double-Strand Breaks to Hold Sister Chromatids Together.

Seeber, Andrew; Hegnauer, Anna Maria; Hustedt, Nicole; Deshpande, Ishan; Poli, Jérôme; Eglinger, Jan; Pasero, Philippe; Gut, Heinz; Shinohara, Miki; Hopfner, Karl-Peter; Shimada, Kenji; Gasser, Susan M.

Mol Cell ; 64(5): 951-966, 2016 12 01.

Artículo en Inglés | MEDLINE | ID: mdl-27889450

18.

Structural and biochemical characterization of human Schlafen 5.

Metzner, Felix J; Huber, Elisabeth; Hopfner, Karl-Peter; Lammens, Katja.

Nucleic Acids Res ; 50(2): 1147-1161, 2022 01 25.

Artículo en Inglés | MEDLINE | ID: mdl-35037067

19.

Mec1, INO80, and the PAF1 complex cooperate to limit transcription replication conflicts through RNAPII removal during replication stress.

Poli, Jérôme; Gerhold, Christian-Benedikt; Tosi, Alessandro; Hustedt, Nicole; Seeber, Andrew; Sack, Ragna; Herzog, Franz; Pasero, Philippe; Shimada, Kenji; Hopfner, Karl-Peter; Gasser, Susan M.

Genes Dev ; 30(3): 337-54, 2016 Feb 01.

Artículo en Inglés | MEDLINE | ID: mdl-26798134

20.

Mre11-Rad50: the DNA end game.