[Familial aggregation of arterial pressure figures and weight indices: study in Cuenca]. / Agregación familiar de cifras de presión arterial e índices ponderales: estudio de Cuenca.

BACKGROUND: The aim of this study was to assess the familial aggregation of blood pressure and body mass index levels in schoolchildren of Cuenca city, Spain. SUBJECTS AND METHODS: A cross sectional study was made including 307 both sexes schoolchildren 9-12 years old recruited in three schools of Cuenca city, and 346 of their parents. There were determined sociodemographics variables, weight, height, body mass index, SBP, DBP and fasting plasma total cholesterol, cLDL, cHDL and triglyceride concentrations. RESULTS: Parents-children correlation coefficients in blood pressure levels ranged between -0.1 and 0.2. Parents-daughters correlations were stronger than parents-sons in ponderal indexes. The relationship of ponderal indexes and blood pressure between spouses was weak, with correlation coefficients between 0.08 y 0.1. By stepwise multiple regression analysis it was found that the only variable that explained a significant percentage of blood pressure variability (both systolic and diastolic) was the weight of the schoolchildren in both sexes. Parents body mass index explained more than 32% of body mass index daughter's variability. In sons any variable explained a significant percentage of variability. CONCLUSIONS: The parents-children aggregation of blood pressure is weak. Parents-children aggregation of ponderal indexes is stronger, though there are considerable sex-differences. Spouses relationship, though positive, is weak in all variables.

[Familial aggregation of lipid and lipoprotein levels: the Cuenca study]. / Agregación familiar de las concentraciones plasmáticas de lípidos y lipoproteínas: estudio de Cuenca.

BACKGROUND: The aim of this study was to assess the familial aggregation of lipid levels in schoolchildren of Cuenca city, Spain. SUBJECTS AND METHODS: A cross sectional study was made including 307 both sexes schoolchildren 9-12 years old recruited in three schools of Cuenca city, and 346 of their parents. Sociodemographics variables, weight, height, body mass index, systolic blood pressure, diastolic blood pressure and fasting plasma total cholesterol, LDL-C, HDL-C and triglyceride concentrations were determined. RESULTS: Father-daughter and mother-daughter Spearman rank correlations coefficients in total cholesterol and LDL-C levels showed values ranging from 0.34 to 0.42 (p < 0.01). Correlation coefficients between both parents and between parents and sons were not significant. By stepwise multiple regression analysis it was found that parents' total cholesterol levels explained almost 30% of cholesterol variability in daughters and 10% in sons. This proportion was about 25% for LDL-C in daughters and was not significant in sons. Parent-children aggregation of HLD-C and triglycerides was weak. CONCLUSIONS: Parent-daughter aggregation of lipid and lipoprotein levels was stronger than parent-son, which has been evidenced mainly in total cholesterol and LDL-C. It has been found no evidence of relation between parents.

Familial aggregation of cardiovascular disease risk factors: the Cuenca Study.

OBJECTIVE: The familial aggregation of lipid levels, blood pressure, and body mass index (BMI) was studied in schoolchildren in Cuenca, Spain. METHODS: A cross-sectional observation study was made of 307 schoolchildren of both sexes, age range 9-12 years, from three schools in Cuenca, Spain, and of 346 parents. Social and demographic variables, weight, height, body mass index, systolic blood pressure, diastolic blood pressure, and fasting plasma concentrations of total cholesterol, LDL-cholesterol, HDL-cholesterol, and triglycerides were evaluated. RESULTS: The Spearman coefficients of correlation for total cholesterol, LDL-cholesterol, and BMI for parents and daughters were 0.34-0.42 (P < 0.01). These coefficients of correlation for parents and sons were lower (P > 0.05). The coefficient of correlation for blood pressure in parents and sons was low (P < 0.05). None of the variables showed any coefficient of correlation between spouses. The sexual differences in the correlations between the levels of the different variables were confirmed by multiple regression analysis. Total cholesterol and LDL-cholesterol levels and BMI accounted for larger percentages of variability in these parameters in daughters than in sons. The paternofilial aggregation of HDL-cholesterol and triglyceride levels was weak. The only variable that accounted for a significant variability in blood pressure (systolic and diastolic) was weight in children of both sexes. CONCLUSIONS: The familial aggregation of lipid levels and body mass index showed sex differences. The paternofilial aggregation of blood pressure was weak. There was no relation between spouses.

[Prevalence of alcoholism in the population attending a urban health center]. / Prevalencia de alcoholismo entre la población que acude a un centro de salud urbano.

OBJECTIVE: To find out the prevalence of alcoholism among those attending an urban Health Centre. To establish the level of concordance between the CAGE and MALT-O tests in the detection of alcoholism and to assess the effectiveness of the joint use of the above tests. DESIGN: Observational, crossover study. SITE. San Ignacio de Loyola Health Centre (Cuenca). PARTICIPANTS: A sample of 499 people of both sexes and over 18 years old was chosen from among the people attending the Centre. Systematic sampling from a random starting-point was used. MAIN MEASUREMENTS AND RESULTS: Each person was interviewed with a questionnaire containing the CAGE and MALT-O items and sociodemographic data. The person who gave at least two positive answers in both tests was considered an alcoholic. A total of 402 filled-in questionnaires were returned. 27 people were found to have two or more positive items, which mean a 6.7% prevalence of alcoholism (CI 95% = 4.2-9.1). This broke down into a prevalence of 1.33% among women and 13.63% among men (p < 0.0001). The concordance level, determined by the Kappa coefficient, between the two tests was 0.29 (CI 95% = 0.11-0.47). CONCLUSIONS: The prevalence of alcoholism found is greater than in other national studies on the out-patient population, although it continues to be low in comparison with several foreign surveys. On the other hand, we seem to gain nothing in the detection of alcoholism by adding the MALT-O to the CAGE test, even when the concordance level between the two tests has come out low.