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1.
Circ J ; 87(2): 268-276, 2023 01 25.
Artículo en Inglés | MEDLINE | ID: mdl-36123011

RESUMEN

BACKGROUND: This study evaluated the association of body mass index (BMI) with adverse clinical outcomes during chronic maintenance antiplatelet monotherapy after percutaneous coronary intervention (PCI) with drug-eluting stents (DES).Methods and Results: Overall, 5,112 patients were stratified (in kg/m2) into underweight (BMI ≤18.4), normal weight (18.5-22.9), overweight (23.0-24.9), obesity (25.0-29.9) and severe obesity (≥30.0) categories with randomized antiplatelet monotherapy of aspirin 100 mg or clopidogrel 75 mg once daily for 24 months. The primary endpoint was the composite of all-cause death, non-fatal myocardial infarction, stroke, readmission due to acute coronary syndrome and major bleeding of Bleeding Academic Research Consortium type ≥3. Compared with normal weight, the risk of primary composite outcomes was higher in the underweight (hazard ratio [HR] 2.183 [1.199-3.974]), but lower in the obesity (HR 0.730 [0.558-0.954]) and severe obesity (HR 0.518 [0.278-0.966]) categories, which is partly driven by the difference in all-cause death. The risk of major bleeding was significantly higher in the underweight (HR 4.140 [1.704-10.059]) than in the normal weight category. A decrease in categorical BMI was independently associated with the increased risk of primary composite outcomes. CONCLUSIONS: Lower BMI is associated with a higher risk of primary composite outcomes, which is primarily related to the events of all-cause death or major bleeding during chronic maintenance antiplatelet monotherapy after PCI with DES.


Asunto(s)
Stents Liberadores de Fármacos , Obesidad Mórbida , Intervención Coronaria Percutánea , Humanos , Inhibidores de Agregación Plaquetaria/uso terapéutico , Aspirina , Índice de Masa Corporal , Stents Liberadores de Fármacos/efectos adversos , Intervención Coronaria Percutánea/efectos adversos , Intervención Coronaria Percutánea/métodos , Obesidad Mórbida/tratamiento farmacológico , Obesidad Mórbida/etiología , Delgadez/inducido químicamente , Delgadez/tratamiento farmacológico , Quimioterapia Combinada , Hemorragia/inducido químicamente , Hemorragia/epidemiología , Obesidad/complicaciones , Resultado del Tratamiento
2.
Catheter Cardiovasc Interv ; 98(4): E548-E554, 2021 10.
Artículo en Inglés | MEDLINE | ID: mdl-34137484

RESUMEN

OBJECTIVES: To evaluate the safety and technical utility of the short track sliding (STS) balloon catheter. BACKGROUND: An STS balloon catheter is designed to ensure a low profile at the shaft and perform distal anchoring using a single guidewire. However, its clinical practice with the STS balloon catheter has not been reported. METHODS: This prospective multi-center registry enrolled 100 patients with significant coronary artery disease who had undergone percutaneous coronary intervention using an STS balloon catheter at three hospitals in Korea from March 2019 to July 2020. Overall safety was assessed as any occurrences of device-related malfunction during the pre-dilation of the lesions. Its technical success rates of the kissing balloon technique or the distal anchoring technique using a single guidewire were also evaluated. RESULTS: Of the 118 lesions pre-dilated using the STS balloon, no significant complication was observed except for three significant coronary dissections, which were completely covered with stents. There was no incidence of balloon catheter malfunction, such as fracture, entrapment, or perforation. With 13 attempts of kissing ballooning techniques with the STS balloon with a 6F guiding catheter, all cases were successful. The distal anchoring techniques were attempted in 10 cases, the stent was successfully crossed to the target lesion in all 10 cases. CONCLUSIONS: The novel STS balloon catheter can be safely applied in routine coronary intervention with minimal complications. In addition, this catheter could be useful for performing the kissing balloon technique with a small-caliber guiding catheter and distal anchoring technique with a single guidewire.


Asunto(s)
Angioplastia Coronaria con Balón , Enfermedad de la Arteria Coronaria , Angioplastia Coronaria con Balón/efectos adversos , Catéteres , Angiografía Coronaria , Enfermedad de la Arteria Coronaria/diagnóstico por imagen , Enfermedad de la Arteria Coronaria/cirugía , Humanos , Estudios Prospectivos , Stents , Resultado del Tratamiento
3.
Environ Sci Technol ; 55(10): 6984-6994, 2021 05 18.
Artículo en Inglés | MEDLINE | ID: mdl-33949853

RESUMEN

A new optimized ultraviolet (UV) technique induced a photooxidation surface modification on thin-film composite (TFC) polyamide (PA) brackish water reverse osmosis (BWRO) membranes that improved membrane performance (i.e., permeability and organic fouling propensity). Commercial PA membranes were irradiated with UV-B light (285 nm), and the changes in the membrane performance were assessed through dead-end and cross-flow tests. UV-B irradiation at 12 J·cm-2 enhanced the pure water permeability by 34% in the dead-end tests without decreasing the mono- or divalent ion rejections, as compared with the pristine PA membrane, and led to less fouling by natural organic matter in the cross-flow tests. Scanning electron microscopy (SEM), attenuated total reflection Fourier transform infrared (ATR-FTIR) spectroscopy, and X-ray photoelectron spectroscopy (XPS) confirmed that UV-B irradiation opened the pore structure and created carboxylic and amine groups on the PA surface, leading to increased membrane surface charge and hydrophilicity. Thus, an optimal UV-B dose appears to modify only a thin layer of the PA membrane surface, which favorably enhances the membrane performance. UV-B did not alter the structure, flux, or salt rejection for cellulose triacetate (CTA)-based membranes. While other membrane surface modifications include oxidants, strong acids, and bases, the UV-B facile treatment is chemical-free, thus reducing chemical wastes, and easy to apply in roll-to-roll fabrication processes of PA membranes. The results also showed that a low UV irradiation dose could be applied to PA or CTA membranes for disinfection or photocatalytic oxidation.


Asunto(s)
Membranas Artificiales , Nylons , Filtración , Ósmosis , Permeabilidad
4.
Bull Environ Contam Toxicol ; 100(1): 120-126, 2018 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-29164274

RESUMEN

Single particle inductively coupled plasma mass spectrometry (spICP-MS) was used to detect Ti-containing particles in heavily-used bathing areas of a river (Salt River) and five swimming pools. Ti-containing particle concentrations in swimming pools ranged from 2.8 × 103 to 4.4 × 103 particles/mL and were an order of magnitude lower than those detected in the Salt River. Measurements from the Salt River showed an 80% increase in Ti-containing particle concentration over baseline concentration during peak recreational activity (at 16:00 h) in the river. Cloud point extraction followed by transmission electron microscopy with energy dispersive X-ray analysis confirmed presence of aggregated TiO2 particles in river samples, showing morphological similarity to particles present in an over-the-counter sunscreen product. The maximum particle mass concentration detected in a sample from the Salt River (659 ng/L) is only slightly lower than the predicted no effect concentration for TiO2 to aquatic organisms (< 1 µg/L).


Asunto(s)
Monitoreo del Ambiente/métodos , Titanio/análisis , Contaminantes Químicos del Agua/análisis , Espectrometría de Masas/métodos , Microscopía Electrónica de Transmisión , Ríos , Análisis Espectral , Protectores Solares/análisis
5.
Environ Sci Technol ; 49(16): 9479-88, 2015 Aug 18.
Artículo en Inglés | MEDLINE | ID: mdl-25581264

RESUMEN

U.S. sewage sludges were analyzed for 58 regulated and nonregulated elements by ICP-MS and electron microscopy to explore opportunities for removal and recovery. Sludge/water distribution coefficients (KD, L/kg dry weight) spanned 5 orders of magnitude, indicating significant metal accumulation in biosolids. Rare-earth elements and minor metals (Y, La, Ce, Pr, Nd, Sm, Eu, Gd, Tb, Dy, Ho, Er, Tm, Yb, Lu) detected in sludges showed enrichment factors (EFs) near unity, suggesting dust or soils as likely dominant sources. In contrast, most platinum group elements (i.e., Ru, Rh, Pd, Pt) showed high EF and KD values, indicating anthropogenic sources. Numerous metallic and metal oxide colloids (<100-500 nm diameter) were detected; the morphology of abundant aggregates of primary particles measuring <100 nm provided clues to their origin. For a community of 1 million people, metals in biosolids were valued at up to US$13 million annually. A model incorporating a parameter (KD × EF × $Value) to capture the relative potential for economic value from biosolids revealed the identity of the 13 most lucrative elements (Ag, Cu, Au, P, Fe, Pd, Mn, Zn, Ir, Al, Cd, Ti, Ga, and Cr) with a combined value of US $280/ton of sludge.


Asunto(s)
Metales/análisis , Aguas del Alcantarillado/química , Aguas Residuales/química , Purificación del Agua/métodos , Arizona , Biomasa , Coloides/química , Microscopía Electrónica de Rastreo , Material Particulado/química , Espectrofotometría Atómica , Estados Unidos , United States Environmental Protection Agency
6.
Environ Sci Technol ; 48(17): 10291-300, 2014 Sep 02.
Artículo en Inglés | MEDLINE | ID: mdl-25122540

RESUMEN

The quantification and characterization of natural, engineered, and incidental nano- to micro-size particles are beneficial to assessing a nanomaterial's performance in manufacturing, their fate and transport in the environment, and their potential risk to human health. Single particle inductively coupled plasma mass spectrometry (spICP-MS) can sensitively quantify the amount and size distribution of metallic nanoparticles suspended in aqueous matrices. To accurately obtain the nanoparticle size distribution, it is critical to have knowledge of the size detection limit (denoted as Dmin) using spICP-MS for a wide range of elements (other than a few available assessed ones) that have been or will be synthesized into engineered nanoparticles. Herein is described a method to estimate the size detection limit using spICP-MS and then apply it to nanoparticles composed of 40 different elements. The calculated Dmin values correspond well for a few of the elements with their detectable sizes that are available in the literature. Assuming each nanoparticle sample is composed of one element, Dmin values vary substantially among the 40 elements: Ta, U, Ir, Rh, Th, Ce, and Hf showed the lowest Dmin values, ≤10 nm; Bi, W, In, Pb, Pt, Ag, Au, Tl, Pd, Y, Ru, Cd, and Sb had Dmin in the range of 11-20 nm; Dmin values of Co, Sr, Sn, Zr, Ba, Te, Mo, Ni, V, Cu, Cr, Mg, Zn, Fe, Al, Li, and Ti were located at 21-80 nm; and Se, Ca, and Si showed high Dmin values, greater than 200 nm. A range of parameters that influence the Dmin, such as instrument sensitivity, nanoparticle density, and background noise, is demonstrated. It is observed that, when the background noise is low, the instrument sensitivity and nanoparticle density dominate the Dmin significantly. Approaches for reducing the Dmin, e.g., collision cell technology (CCT) and analyte isotope selection, are also discussed. To validate the Dmin estimation approach, size distributions for three engineered nanoparticle samples were obtained using spICP-MS. The use of this methodology confirms that the observed minimum detectable sizes are consistent with the calculated Dmin values. Overall, this work identifies the elements and nanoparticles to which current spICP-MS approaches can be applied, in order to enable quantification of very small nanoparticles at low concentrations in aqueous media.


Asunto(s)
Elementos Químicos , Límite de Detección , Nanopartículas/química , Tamaño de la Partícula , Espectrofotometría Atómica/métodos , Ambiente , Humanos , Nanotecnología , Ríos/química , Eliminación de Residuos Líquidos , Aguas Residuales/química , Agua/química
7.
JACC Cardiovasc Interv ; 17(3): 329-340, 2024 Feb 12.
Artículo en Inglés | MEDLINE | ID: mdl-38355261

RESUMEN

BACKGROUND: Distal radial access (DRA) as an alternative access route lacks evidence, despite its recent reputation. OBJECTIVES: The aim of this study was to evaluate the safety and feasibility of DRA on the basis of daily practice. METHODS: The KODRA (Korean Prospective Registry for Evaluating the Safety and Efficacy of Distal Radial Approach) trial was a prospective multicenter registry conducted at 14 hospitals between September 2019 and September 2021. The primary endpoints were the success rates of coronary angiography (CAG) and percutaneous coronary intervention (PCI). The secondary endpoints included successful distal radial artery puncture, access-site crossover, access site-related complications, bleeding events, and predictors of puncture failure. RESULTS: A total of 4,977 among 5,712 screened patients were recruited after the exclusion of 735 patients. The primary endpoints, the success rates of CAG and PCI via DRA, were 100% and 98.8%, respectively, among successful punctures of the distal radial artery (94.4%). Access-site crossover occurred in 333 patients (6.7%). The rates of distal radial artery occlusion and radial artery occlusion by palpation were 0.8% (36 of 4,340) and 0.8% (33 of 4,340) at 1-month follow-up. DRA-related bleeding events were observed in 3.3% of patients, without serious hematoma. Multilevel logistic regression analysis identified weak pulse (OR: 9.994; 95% CI: 7.252-13.774) and DRA experience <100 cases (OR: 2.187; 95% CI: 1.383-3.456) as predictors of puncture failure. CONCLUSIONS: In this large-scale prospective multicenter registry, DRA demonstrated high success rates of CAG and PCI, with a high rate of puncture success but low rates of distal radial artery occlusion, radial artery occlusion, bleeding events, and procedure-related complications. Weak pulse and DRA experience <100 cases were predictors of puncture failure. (Korean Prospective Registry for Evaluating the Safety and Efficacy of Distal Radial Approach [KODRA]; NCT04080700).


Asunto(s)
Arteriopatías Oclusivas , Intervención Coronaria Percutánea , Humanos , Intervención Coronaria Percutánea/efectos adversos , Intervención Coronaria Percutánea/métodos , Resultado del Tratamiento , Arteria Radial/diagnóstico por imagen , Angiografía Coronaria/métodos , Hemorragia/etiología , Arteriopatías Oclusivas/complicaciones , Sistema de Registros
8.
Chemosphere ; 335: 139032, 2023 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-37236275

RESUMEN

Although spectroscopic methods provide a fast and cost-effective means of monitoring dissolved organic carbon (DOC) in natural and engineered water systems, the prediction accuracy of these methods is limited by the complex relationship between optical properties and DOC concentration. In this study, we developed DOC prediction models using multiple linear/log-linear regression and feedforward artificial neural network (ANN) and investigated the effectiveness of spectroscopic properties, such as fluorescence intensity and UV absorption at 254 nm (UV254), as predictors. Optimum predictors were identified based on correlation analysis to construct models using single and multiple predictors. We compared the peak-picking and parallel factor analysis (PARAFAC) methods for selecting appropriate fluorescence wavelengths. Both methods had similar prediction capability (p-values >0.05), suggesting PARAFAC was not necessary for choosing fluorescence predictors. Fluorescence peak T was identified as a more accurate predictor than UV254. Combining UV254 and multiple fluorescence peak intensities as predictors further improved the prediction capability of the models. The ANN models outperformed the linear/log-linear regression models with multiple predictors, achieving higher prediction accuracy (peak-picking: R2 = 0.8978, RMSE = 0.3105 mg/L; PARAFAC: R2 = 0.9079, RMSE = 0.2989 mg/L). These findings suggest the potential to develop a real-time DOC concentration sensor based on optical properties using an ANN for signal processing.


Asunto(s)
Contaminantes Químicos del Agua , Purificación del Agua , Materia Orgánica Disuelta , Espectrometría de Fluorescencia/métodos , Contaminantes Químicos del Agua/análisis , Purificación del Agua/métodos , Agua
9.
Materials (Basel) ; 16(8)2023 Apr 18.
Artículo en Inglés | MEDLINE | ID: mdl-37110028

RESUMEN

In this study, the characteristics of the SKD61 material used for the stem of an extruder were analyzed through structural analysis, tensile testing, and fatigue testing. The extruder works by pushing a cylindrical billet into a die with a stem to reduce its cross-sectional area and increase its length, and it is currently used to extrude complex and diverse shapes of products in the field of plastic deformation processes. Finite element analysis was used to determine the maximum stress on the stem, which was found to be 1152 MPa, lower than the yield strength of 1325 MPa obtained from tensile testing. Fatigue testing was conducted using the stress-life (S-N) method, considering the characteristics of the stem, and statistical fatigue testing was employed to create an S-N curve. The predicted minimum fatigue life of the stem at room temperature was 424,998 cycles at the location with the highest stress, and the fatigue life decreased with increasing temperature. Overall, this study provides useful information for predicting the fatigue life of extruder stems and improving their durability.

10.
J Clin Hypertens (Greenwich) ; 25(9): 828-844, 2023 09.
Artículo en Inglés | MEDLINE | ID: mdl-37584254

RESUMEN

The authors performed this study to investigate the efficacy and safety of a rosuvastatin (RSV)/amlodipine (AML) polypill compared with those of atorvastatin (ATV)/AML polypill. We included 259 patients from 21 institutions in Korea. Patients were randomly assigned to 1 of 3 treatment groups: RSV 10 mg/AML 5 mg, RSV 20 mg/AML 5 mg, or ATV 20 mg /AML 5 mg. The primary endpoint was the efficacy of the RSV 10.20 mg/AML 5 mg via percentage changes in LDL-C after 8 weeks of treatment, compared with the ATV 20 mg /AML 5 mg. There was a significant difference in the mean percentage change of LDL-C at 8 weeks between the RSV 10 mg/AML 5 mg and the ATV 20 mg/AML 5 mg (full analysis set [FAS]: -7.08%, 95% CI: -11.79 to -2.38, p = .0034, per-protocol analysis set [PPS]: -6.97%, 95% CI: -11.76 to -2.19, p = .0046). Also, there was a significant difference in the mean percentage change of LDL-C at 8 weeks between the RSV 20 mg/AML 5 mg and the ATV 20 mg/AML 5 mg (FAS: -10.13%, 95% CI: -15.41 to -4.84, p = .0002, PPS: -10.96%, 95% CI: -15.98 to -5.93, p < .0001). There was no significant difference in the adverse events rates between RSV 10 mg/AML 5 mg, RSV 20 mg/AML 5 mg, and ATV 20 mg/AML 5 mg. In conclusion, while maintaining safety, RSV 10 mg/AML 5 mg and the RSV 20 mg/AML 5 mg more effectively reduced LDL-C compared with the ATV 20 mg /AML 5 mg (Clinical trial: NCT03951207).


Asunto(s)
Dislipidemias , Hipertensión , Leucemia Mieloide Aguda , Humanos , Rosuvastatina Cálcica/efectos adversos , Atorvastatina/efectos adversos , Amlodipino/efectos adversos , Hipertensión/tratamiento farmacológico , Hipertensión/inducido químicamente , LDL-Colesterol , Dislipidemias/tratamiento farmacológico , Leucemia Mieloide Aguda/inducido químicamente , Método Doble Ciego , Resultado del Tratamiento
11.
Membranes (Basel) ; 12(2)2022 Feb 09.
Artículo en Inglés | MEDLINE | ID: mdl-35207124

RESUMEN

Due to advances in desalination technology, desalination has been considered as a practical method to meet the increasing global fresh water demand. This paper explores the status of the desalination industry and research work in South Korea. Desalination plant designs, statistics, and the roadmap for desalination research were analyzed. To reduce energy consumption in desalination, seawater reverse osmosis (SWRO) has been intensively investigated. Recently, alternative desalination technologies, including forward osmosis, pressure-retarded osmosis, membrane distillation, capacitive deionization, renewable-energy-powered desalination, and desalination batteries have also been actively studied. Related major consortium-based desalination research projects and their pilot plants suggest insights into lowering the energy consumption of desalination and mitigation of the environmental impact of SWRO brine as well. Finally, considerations concerning further development are suggested based on the current status of desalination technology in South Korea.

12.
Water Res ; 226: 119300, 2022 Nov 01.
Artículo en Inglés | MEDLINE | ID: mdl-36323221

RESUMEN

Interplays between microalgae and clay minerals enhance biologically mediated flocculation, thereby affecting the sedimentation and transportation of suspended particulate matter (SPM) in water and benthic environments. This interaction forms larger flocs with a higher settling velocity and enhances SPM sinking. The aim of this study was to investigate the flocculation kinetics of microalgae and clay in suspension and to elucidate the mechanisms associated with such interactions. Standard jar test experiments were conducted using various mixtures of kaolinite and microalgal samples from batch cultures (Chlorella vulgaris) to estimate biologically mediated flocculation kinetics. The organic matter (OM) composition secreted by the microalgae was characterized using a liquid chromatography - organic carbon detection system, and quantitative analysis of transparent exopolymer particles was conducted separately. A two-class flocculation kinetic model, based on the interaction between flocculi and flocs, was also adopted to quantitatively analyze the experimental data from flocculation. Results from the flocculation kinetic tests and OM analyses, in association with other data analyses (i.e., floc size distribution and flocculation kinetic model), showed that flocculation increased with OM concentration during the growth phase (10-20 d). However, on day 23 during the early stationary phase, flocculation kinetics started decreasing and substantially declined on day 30, even though the amount of OM (mainly biopolymers) continued to increase. Our results indicate that an adequate quantity of biopolymers produced by the microalgal cells in the growth phase enhanced floc-to-floc attachment and hence flocculation kinetics. In contrast, an excessive quantity of biopolymers and humic substances in the stationary phase enhanced the formation of polymeric backbone structures and flocculation via scavenging particles but simultaneously increased steric stabilization with the production of a large number of fragmented particles.


Asunto(s)
Chlorella vulgaris , Microalgas , Floculación , Arcilla , Suspensiones , Cinética
13.
Membranes (Basel) ; 10(11)2020 Oct 30.
Artículo en Inglés | MEDLINE | ID: mdl-33143029

RESUMEN

We compared two representative forward osmosis (FO) modules-spiral-wound (SW) and plate-and-frame (PF)-to provide practical information for the selection of FO element for a large-scale FO process. The FO operating performance of commercially available SW FO and PF FO was explored under different membrane area and flow rate conditions. The performance trend as a function of the membrane was obtained by adjusting the number of serially connected elements. Although SW FO and PF FO elements exhibited comparable feed pressure drops, SW FO demonstrated a significantly higher draw channel pressure drop than PF FO. Furthermore, the significant draw pressure drop in SW FO increased the draw inlet pressure, consequently limiting the number of serially connected elements. For example, the maximum number of serially connected elements for the normal operation was three elements for SW FO (45.9 m2) but nine elements for PF FO (63 m2) when the flow rate of 10 LMP was applied for feed and draw streams. Additionally, a footprint analysis indicated that SW FO module exhibited a slightly larger footprint than PF FO. Under investigated conditions, PF FO exhibited relatively better performance than SW FO. Therefore, this pilot-scale FO study highlighted the need to reduce the flow resistance of SW FO draw channel to take advantage of the high packing density of the SW element.

14.
Membranes (Basel) ; 10(3)2020 Mar 24.
Artículo en Inglés | MEDLINE | ID: mdl-32213880

RESUMEN

Forward osmosis (FO) technology has increasingly attracted attention owing to its low operational energy and low fouling propensity. Despite extensive investigations on FO, very few module-scale FO studies on the operation and design of the FO process have been conducted. In this paper, a simple and practical FO process design parameter called normalized membrane area is suggested based on a performance analysis of spiral-wound FO elements. The influence of operation factors on operating pressures and water recovery was investigated using 8-inch spiral wound elements in the continuous operation mode. The membrane area was adjusted by series connection of FO elements to a maximum value of 46 m2 (three elements). The feed and draw flow rates were varied between 5 and 15 LPM under various feed (10, 20, and 30 g/L) and draw (58.4 and 233.8 g/L) concentration combinations. The analysis of flow rates (feed, draw, and permeate flow rates) indicated not only high flow channel resistance on the draw side but also high permeate flow rates can induce higher operating pressures owing to strong mutual interaction of the feed and the draw streams. Feed water recovery was focused on as a key performance index, and the experimental recovery (RExp) and theoretical maximum recovery (RTh) values were compared. The results revealed the significance of the feed flow rate and the membrane area in terms of enhancing the water recovery performance. In addition, a clear relationship was observed between the membrane area normalized by the initial feed flow rates and the water recovery ratio (RExp/RTh), even though the applied operation conditions were different. Finally, an empirical equation to estimate the required membrane area of spiral-wound FO was proposed for the FO process design. The equation can be used to predict water recovery of FO systems as well, for example, if an FO system is operated at 0.08 m2L-1h of the normalized membrane area, the system is expected to offer 78% of the RTh value.

15.
Materials (Basel) ; 13(24)2020 Dec 09.
Artículo en Inglés | MEDLINE | ID: mdl-33317047

RESUMEN

Recently, mechanical joining processes have received much attention for joining multi-materials. In particular, these processes have a great demand in the automobile industry for weight reduction. The press-fitting process is a representative mechanical joining process. In this process, the shape of the interfacial serration on the joining plane is very important because it has a significant effect on the joining strength. In this study, the characteristics of the aluminum-steel press joining process were investigated according to the shape of the interfacial serration of the joining plane. The deformation of the material and the forming load were investigated by conducting finite element analysis. In addition, the unfilled height of the material, joining force, and torque were measured experimentally.

16.
Sci Rep ; 10(1): 7104, 2020 04 28.
Artículo en Inglés | MEDLINE | ID: mdl-32346022

RESUMEN

Medical radiation exposure is a significant concern for interventional cardiologists (IC). This study was aimed at estimating the radiation exposure of IC operators and assistants in real clinical practice. The radiation exposure of the operator and assistant was evaluated by conducting two types of procedures via coronary angiography (CAG) and percutaneous coronary intervention (PCI) on 1090 patients in 11-cardiovascular centers in Korea. Radiation exposure was measured using an electronic personal dosimeter (EPD). EPD were attached at 3 points on each participant: on the apron on the left anterior chest (A1), under the apron on the sternum (A2), and on the thyroid shield (T). Average radiation exposure (ARE) of operators at A1, A2, and T was 19.219 uSv, 4.398 uSv, and 16.949 uSv during CAG and 68.618 uSv, 15.213 uSv, and 51.197 uSv during PCI, respectively. ARE of assistants at A1, A2, and T was 4.941 uSv, 0.860 uSv, and 5.232 uSv during CAG and 20.517 uSv, 4.455 uSv, and 16.109 uSv during PCI, respectively. AED of operator was 3.4 times greater during PCI than during CAG.


Asunto(s)
Angiografía Coronaria , Arteria Femoral/diagnóstico por imagen , Exposición Profesional , Intervención Coronaria Percutánea , Arteria Radial/diagnóstico por imagen , Dosis de Radiación , Exposición a la Radiación , Femenino , Humanos , Masculino , Persona de Mediana Edad
17.
J Nanosci Nanotechnol ; 19(12): 7753-7757, 2019 Dec 01.
Artículo en Inglés | MEDLINE | ID: mdl-31196285

RESUMEN

Si nanoparticles uniformly coated with Co-containing N-doped carbon were investigated as an anode material for Li-ion batteries. The Si nanoparticle surfaces were modified with conductive and matrix, N-doped carbon and cobalt element and prepared by a simple pyrolysis process using an ionic liquid that contained nitrogen with metal complex. After a simple annealing process, the N-doped carbon containing cobalt element was uniformly coated onto the Si nanoparticles. The smooth carbon layer connected the Si nanoparticles without any morphological changes. Si nanoparticles containing 34 wt% N-doped carbon and cobalt element exhibited a stable electrochemical performance with a capacity of ~1133 mAh g-1 and excellent capacity retention over 60 cycles. The high electrochemical performances was attributed to the synergistic effect by presence cobalt in N-doped carbon matrix, which alleviated the lithium-silicon alloying reaction-induced volume expansion and enhanced electrical conductivity during cycling.

18.
Materials (Basel) ; 12(23)2019 Nov 27.
Artículo en Inglés | MEDLINE | ID: mdl-31783542

RESUMEN

In the multi-pass wire drawing process, the diameter of a wire is decreased by continuously passing it through progressively smaller drawing dies. Although the deformation depends on the process variables, in most wire drawing processes, the wire deformation is concentrated on the surface by its direct contact with the drawing dies, causing a nonlinear distribution of radial direction effective strain from the center to the surface. In this study, a new model for predicting this effective strain in two-pass drawn wire was derived based on the upper bound method, and a finite element analysis and drawing experiment were conducted to validate its effectiveness. The proposed model offers a promising approach to determining and thus controlling the strain in multi-pass drawn wire.

19.
Materials (Basel) ; 12(13)2019 Jul 08.
Artículo en Inglés | MEDLINE | ID: mdl-31288416

RESUMEN

Rhodium is a rare material that is widely used in electrical and electronic components due to its excellent mechanical and electrical properties. Ultra-fine rhodium wires in particular are widely used in electronic components. In this study, a multi-pass wire drawing process was designed to fabricate ultra-fine pure rhodium wire with a diameter of 50.0 µm from an initial diameter of 80.0 µm, which is used as probe card pins. An elastic-plastic finite element (FE) analysis was performed to validate the pass schedule that was designed for this study. A fine wire drawing experiment was also carried out to verify the effectiveness of the designed process. As a result, the ultra-fine rhodium wire was fabricated using the design process without wire breaks and the diameter of the final drawn wire was 47.80 µm.

20.
Materials (Basel) ; 11(12)2018 Dec 03.
Artículo en Inglés | MEDLINE | ID: mdl-30513918

RESUMEN

The process design of a multi-pass steel profile drawing depends mainly on the experience of the industrial experts. Therefore, in the actual industrial field, a systematic design method is required to improve the efficiency of process design. Development of such a method will result in a reduction in production cost and time. In this study, a process design system that can be installed in AutoCAD V14 was developed. By using the developed design system, the drawing load, stress, and strain, among other parameters, can be calculated. In addition, intermediate die shapes can be designed. After the process design, both process information and drawings of dies can be obtained. In order to verify the effectiveness of the developed process design system, it was used to design multi-pass profile drawing processes. Finally, finite element (FE) analysis and a drawing experiment were carried out to verify the designed processes.

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