RESUMEN
We report the first case of anaphylaxis to oral vancomycin in a cystic fibrosis patient with severe and relapsing Clostridium difficile infection (CDI) refractory to metronidazole. The patient's colitis has been successfully treated with a combination of intravenous metronidazole and tigecycline.
Asunto(s)
Anafilaxia/inducido químicamente , Antibacterianos/efectos adversos , Infecciones por Clostridium/tratamiento farmacológico , Vancomicina/efectos adversos , Administración Oral , Adulto , Antibacterianos/uso terapéutico , Clostridioides difficile , Fibrosis Quística/complicaciones , Diarrea/microbiología , Enterocolitis Seudomembranosa/tratamiento farmacológico , Humanos , Masculino , Metronidazol/uso terapéutico , Minociclina/análogos & derivados , Minociclina/uso terapéutico , Índice de Severidad de la Enfermedad , TigeciclinaRESUMEN
Over 1500 population database samples comprising African Americans, Caucasians, Hispanics, Native Americans, Chamorros and Filipinos were typed using the PowerPlex 16 and the Profiler Plus/COfiler kits. Except for the D8S1179 locus in Chamorros and Filipinos from Guam, there were eight examples in which a typing difference due to allele dropout was observed. At the D8S1179 locus in the population samples from Guam, there were 13 examples of allele dropout observed when using the Profiler Plus kit. The data support that the primers used in the PowerPlex 16, Profiler Plus, and COfiler kits are reliable for typing reference samples that are for use in CODIS. In addition, allele frequency databases have been established for the STR loci Penta D and Penta E. Both loci are highly polymorphic.
Asunto(s)
Medicina Legal , Genética de Población , Grupos Raciales/genética , Secuencias Repetidas en Tándem , Alelos , Bases de Datos Factuales , Humanos , Estados UnidosRESUMEN
Using scanning tunneling microscopy and infrared reflection absorption spectroscopy we have observed that the alpha-Fe2O3(0001) surface exhibits ferryl (Fe=O) groups, which may coexist with domains of the Fe-terminated surface. We therefore fully support ab initio calculations recently reported in the literature [W. Bergmeyer, H. Schweiger, and E. Wimmer, Phys. Rev. B 69, 195409 (2004)]. The close similarity to the results on the (0001) surfaces of Cr2O3 and V2O3 strongly suggests that the M=O termination under certain oxygen pressure conditions is the most stable for the close-packed surfaces of transition metal oxides with the corundum structure.