[Single center analysis of the dermatosurgical patient cohort of a tumor center in Germany]. / Betrachtung des dermatochirurgischen Patientenkollektivs an einem Hauttumorzentrum in Deutschland.

BACKGROUND: The incidence of skin cancer continues to increase. However, little is known about the dermatosurgical characteristics of the patients. PATIENTS AND METHODS: In this single center, retrospective study, dermatosurgical reports of all patients treated because of basal cell carcinomas (BCC), squamous cell carcinomas (SCC), and malignant melanoma (MM) between 2004 and 2013 were analyzed. RESULTS: During the observed period, the number of operated BCC rose by a factor of 1.86 and the number of MM by a factor of 2.3. In comparison to BCC/MM, there was a disproportionately high increase of SCC by a factor of 4.02. The average age was 71.5 ± 13.4 years (minimum: 14 years; maximum: 104 years), whereupon a significant increase of male age and a significant decrease of female age occurred. Almost 70% of all tumors were located in the head and neck area. The nose was most commonly treated. CONCLUSIONS: During the last 10 years, the cohort of dermatosurgical patients changed in the tumor center. This should be verified in multicenter studies.

[Effect of occupational lead exposure on the immunoglobulin concentration and cellular immune function in man]. / Influencia de la exposición ocupacional al plomo sobre la concentración de inmunoglobulinas y la función celular inmune en el hombre.

The evaluation of immunological conditions of 14 workers occupationally exposed to lead and comparison of these results with those of a non-exposed control group with similar age and sex were the aims of this study. It was determined the mean values of lead in blood. In exposed workers it was 46.9 ug/dl while in the control group it was 10.9 ug/dl. Levels of immunoglobulin decreasing while increasing lead concentration in blood were found in those exposed. It was also found a significant diminishment in the formation of rosette in relation to the control group.

[Effect of occupational lead exposure on immunoglobulin concentration and cellular immune function in man]. / Influencia de la exposición laboral al plomo sobre la concentración de inmunoglobulinas y la función celular inmunitaria en el hombre.

The evaluation of immunological conditions of 14 workers occupationally exposed to lead and the comparison of these results with those of a non-exposed control group with similar age and sex were the aims of this study. It was determined the mean values of lead in blood. In exposed workers it was 46.9 micrograms/dl while in the control group it was 10.9 micrograms/dl. Levels of immunoglobulin decreasing while increasing lead concentration in blood were found in those exposed. It was also found a significant decrease in the formation for rosette in relation to the control group.

[Value of delayed skin test in elderly patients]. / Valor de la prueba cutánea tardía en pacientes de la tercera edad.

BACKGROUND: Retarded cutaneous hypersensitivity to several antigens has been studied in human of different ages and in people older than 60 years a diminishment in response to tests measuring retarded hypersensitivity has been observed. OBJECTIVE: To determine the pattern of response to tests of retarded hypersensitivity in an apparently healthy sample of Cuban population resident at La Habana City, by application of a group of cutaneous tests with national antigens. MATERIAL AND METHODS: Intradermal tests were applied to 87 subjects (69 women and 18 men) between 60 and 89 years old, without frequent infection antecedents. All subjects were submitted to clinical history and analysis in order to discard diseases that may alter the study proposal. Response grade was determined by summing media of induration diameters, which was denominated total media punctuation. RESULTS: In all age groups total media punctuation was lightly higher in women, in both control and study groups, excepting age group of 80-89 years. CONCLUSION: By virtue of there are few indicators of health for old people, the group of tests proposed in this article may be a good predictive indicator of morbidity and mortality in old patients.

[Influence of occupational lead exposure on the concentration of immunoglobins and immune cellular functions in humans]. / Influencia de la exposición ocupacional al plomo sobre la concentración de inmunoglobulinas y la función celular inmune en el hombre.

The evaluation of immunological conditions of 14 workers occupationally exposed to lead, and the comparison of these results with those of a non-exposed control group, with similar age and sex, were the aims of this study. It was determined the mean values of lead in blood. In exposed workers it was 46.9 micrograms/dl; while in the control group it was 10.9 micrograms/dl. Levels of immunoglobulin decreasing while increasing lead concentration in blood were found in those exposed. It was also found a significant lessening in the formation of rosette in relation to the control group.

Influencia de la exposición laboral al plomo sobre la concentración de inmunoglobulinas y la función celular inmunitaria en el hombre / Influence of the ocupational exposed to lead on the inmunoglobulins concentration and cellular inmune function in man

Se evaluó el estado inmunológico de 14 trabajadores expuestos por razones de su ocupación al plomo, los sujetos estudiados se compararon con otros no expuestos, de edad y sexo similares (grupo testigo). La concentración medida de plomo en la sangre de la población expuesta fue 46,9 ñ 2,3 µg/dl. No hubo diferencias significativas en las concentraciones del suero IgG, IgA e IgM entre las poblaciones estudiadas. Se comprobó la correlación entre la concentración de plomo en sangre y el inmunoglobulinas G

Influencia de la exposición ocupacional el plomo sobre la concentración de inmunoglobulinas y la función celular inmune en el hombre / Influency of the lead occupational exposition over inmunoglobulins leucls and the immunocellular function in the worker

La evaluación del estado inmunológico en trabajadores expuestos en razón de su trabajo al plomo fue el motivo de este estudio realizado a 14 trabajadores, los que fueron comparados con otros no expuestos, de edad y sexos similares (grupo control).La concentración media de plomo en sangre de la población expuesta fue de 46.9+- 2.3 ng/dl. No hubo diferencias significativas en las concentraciones del suero IgC, IgA e IgM entre las poblaciones estudiadas. Se comprobó la correlación entre la concentración de plomo en la sangre y los niveles de inmunoglobulinas G. Encontramos alteraciones significativas en las pruebas de formación de rosetas (R A y R E)

Estrés y alteraciones de la reacción inmunitaria en sujetos de la tercera edad / Stress and alterations of the immune reaction in elderly subjects

La evaluación de algunos aspectos de la reacción inmunitaria en el anciano estresado fue la finalidad de este estudio que se realizó a 96 personas de la tercera edad. Los sujetos de estudio se dividieron por grupos de edades a partir de los 60 años, tomándose el grupo de edades a partir de los 60 años, tomándose el grupo de ancianos no estresados como grupo testigo. No hubo diferencias significativas en las concentraciones de inmunoglobulina A, G, M, en el seno de la población estudiada. Se encontraron elteraciones significativas en la prueba de formación de roseta espontánea del grupo estresado